X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (48341) 48341
Publication (5943) 5943
Book Review (3266) 3266
Book Chapter (315) 315
Conference Proceeding (138) 138
Newsletter (124) 124
Book / eBook (32) 32
Dissertation (18) 18
Journal / eJournal (4) 4
Newspaper Article (3) 3
Web Resource (3) 3
Data Set (2) 2
Magazine Article (2) 2
Reference (2) 2
Paper (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (46672) 46672
animals (30474) 30474
phosphoproteins - metabolism (25061) 25061
humans (23326) 23326
phosphorylation (17843) 17843
biochemistry & molecular biology (13743) 13743
mice (12023) 12023
phosphoproteins - genetics (10429) 10429
cell biology (9969) 9969
rats (8281) 8281
male (8028) 8028
signal transduction (7652) 7652
molecular sequence data (7319) 7319
phosphoprotein phosphatases - metabolism (7058) 7058
proteins (6913) 6913
amino acid sequence (6499) 6499
female (6462) 6462
cell line (6196) 6196
cells, cultured (5378) 5378
expression (5259) 5259
protein binding (4994) 4994
research (4170) 4170
activation (4123) 4123
phosphoproteins - chemistry (3711) 3711
cells (3658) 3658
phosphoproteins (3621) 3621
mutation (3478) 3478
kinetics (3405) 3405
membrane proteins - metabolism (3368) 3368
gene expression (3315) 3315
base sequence (3247) 3247
binding sites (3046) 3046
protein kinases - metabolism (2977) 2977
transfection (2965) 2965
protein (2958) 2958
physiological aspects (2866) 2866
blotting, western (2849) 2849
cell line, tumor (2842) 2842
oncology (2833) 2833
article (2822) 2822
nuclear proteins - metabolism (2805) 2805
dna-binding proteins - metabolism (2729) 2729
identification (2651) 2651
molecular weight (2628) 2628
multidisciplinary sciences (2625) 2625
apoptosis (2588) 2588
analysis (2582) 2582
enzyme activation (2497) 2497
phosphoproteins - physiology (2446) 2446
adaptor proteins, signal transducing - metabolism (2434) 2434
carrier proteins - metabolism (2417) 2417
rna, messenger - metabolism (2411) 2411
time factors (2402) 2402
neurosciences (2382) 2382
phosphoprotein phosphatases - antagonists & inhibitors (2371) 2371
enzyme inhibitors - pharmacology (2360) 2360
phosphoprotein phosphatases - genetics (2347) 2347
endocrinology & metabolism (2330) 2330
abridged index medicus (2328) 2328
transcription factors - metabolism (2307) 2307
protein-serine-threonine kinases - metabolism (2267) 2267
biophysics (2191) 2191
tumor cells, cultured (2174) 2174
immunohistochemistry (2145) 2145
gene-expression (2114) 2114
phosphoproteins - biosynthesis (2107) 2107
binding (2100) 2100
protein structure, tertiary (2096) 2096
cancer (2089) 2089
gene (2085) 2085
kinases (2050) 2050
signal transduction - physiology (2038) 2038
gene expression regulation (2011) 2011
insulin receptor substrate proteins (2006) 2006
adaptor proteins, signal transducing (1985) 1985
hela cells (1977) 1977
phosphatases (1972) 1972
rats, sprague-dawley (1958) 1958
phosphoproteins - analysis (1948) 1948
immunology (1927) 1927
tyrosine - metabolism (1923) 1923
protein-tyrosine kinases - metabolism (1918) 1918
kinase (1906) 1906
mice, inbred c57bl (1897) 1897
mice, knockout (1878) 1878
phosphorylation - drug effects (1852) 1852
genetic aspects (1835) 1835
models, biological (1812) 1812
proteins - metabolism (1795) 1795
electrophoresis, polyacrylamide gel (1782) 1782
sequence homology, amino acid (1772) 1772
transcription, genetic (1762) 1762
adult (1740) 1740
in vitro techniques (1740) 1740
in-vivo (1729) 1729
genetics & heredity (1709) 1709
research article (1700) 1700
genes (1698) 1698
signal transduction - drug effects (1692) 1692
rna, messenger - genetics (1675) 1675
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (22) 22
Collection Dvlpm't (Acquisitions) - Vendor file (4) 4
Gerstein Science - Periodical Stacks (4) 4
Online Resources - Online (4) 4
Collection Dvlpm't (Acquisitions) - Closed Orders (2) 2
Chemistry (A D Allen) - Stacks (1) 1
UofT at Mississauga - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (47959) 47959
Chinese (233) 233
Japanese (176) 176
Russian (97) 97
French (39) 39
Polish (17) 17
Spanish (11) 11
German (7) 7
Swedish (6) 6
Italian (5) 5
Ukrainian (5) 5
Croatian (2) 2
Czech (1) 1
Dutch (1) 1
Korean (1) 1
Serbian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Cell Biology, ISSN 1465-7392, 2014, Volume 16, Issue 4, pp. 357 - 366
The YAP and TAZ mediators of the Hippo pathway ( hereafter called YAP/TAZ) promote tissue proliferation and organ growth. However, how their biological... 
ORGAN GROWTH | CHOLESTEROL | YAP/TAZ | TRANSCRIPTION | HIPPO PATHWAY | STATINS | CELL BIOLOGY | Phosphorylation - physiology | Cell Proliferation | Active Transport, Cell Nucleus - physiology | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Drosophila Proteins - metabolism | Phosphoproteins - metabolism | Sterol Regulatory Element Binding Proteins - genetics | Breast Neoplasms - metabolism | Drosophila melanogaster - metabolism | RNA Interference | Tumor Suppressor Proteins - genetics | HEK293 Cells | Trans-Activators - genetics | Female | Transcription, Genetic | Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | HCT116 Cells | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Sterol Regulatory Element Binding Proteins - metabolism | Transcription Factors - genetics | Mevalonic Acid - metabolism | Polyisoprenyl Phosphates - metabolism | Transcription Factors - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | rho GTP-Binding Proteins - metabolism | Trans-Activators - metabolism | Mice | Polyisoprenyl Phosphates - biosynthesis | Pyridines - pharmacology | RNA, Small Interfering | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cell metabolism | Genetic research | Genetic aspects | Research | Cellular control mechanisms | Index Medicus
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2016, Volume 99, Issue 5, pp. 1190 - 1198
Uveal melanoma (UM) is a rare intraocular tumor that, similar to cutaneous melanoma, originates from melanocytes. To gain insights into its genetics, we... 
OCULAR MELANOMA | CELLS | COLORECTAL-CANCER | PROTEINS DLK1 | METASTASES | GENETICS & HEREDITY | RISK | EXPRESSION | RADIATION | SF3B1 | SOMATIC MUTATIONS | Melanoma - diagnosis | Exons | Humans | Middle Aged | Male | Phosphoproteins - metabolism | Case-Control Studies | RNA Splicing Factors - metabolism | DNA Copy Number Variations | Melanoma - genetics | Melanocytes - pathology | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Ubiquitin Thiolesterase - metabolism | Adult | Female | Membrane Proteins - metabolism | Eukaryotic Initiation Factor-1 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Tumor Suppressor p53-Binding Protein 1 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Uveal Neoplasms - genetics | Genome-Wide Association Study | Tumor Suppressor Proteins - metabolism | GTP-Binding Protein alpha Subunits - metabolism | Tumor Suppressor p53-Binding Protein 1 - genetics | Membrane Proteins - genetics | Eukaryotic Initiation Factor-1 - genetics | Ubiquitin-Protein Ligases - metabolism | GTP-Binding Protein alpha Subunits - genetics | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Ubiquitin Thiolesterase - genetics | Skin Neoplasms | Uveal Neoplasms - diagnosis | Aged | Mutation | Ubiquitin-Protein Ligases - genetics | Genetic aspects | Nucleotide sequencing | Methods | Melanoma | DNA sequencing | Metastasis | Pathogenesis | Genomics | Deoxyribonucleic acid--DNA | Index Medicus | Report
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 47, Issue 6, pp. 817 - 831
The molecular mechanisms controlling the differentiation of neural progenitors into distinct subtypes of neurons during neocortical development are unknown.... 
AREA IDENTITY | NEOCORTICAL NEURONS | CELL FATE SPECIFICATION | CEREBRAL CORTICAL DEVELOPMENT | LAYER NEURONS | CENTRAL-NERVOUS-SYSTEM | SUBCORTICAL TARGETS | ZINC-FINGER GENE | SUBVENTRICULAR ZONE | NEUROSCIENCES | ZEBRAFISH FOREBRAIN | Membrane Glycoproteins - metabolism | Embryo, Mammalian | Homeodomain Proteins - metabolism | Nerve Tissue Proteins - deficiency | S100 Proteins - genetics | POU Domain Factors - genetics | Forkhead Transcription Factors - metabolism | In Situ Hybridization - methods | Repressor Proteins - metabolism | Gene Expression Regulation, Developmental - physiology | POU Domain Factors - metabolism | Animals, Newborn | DNA-Binding Proteins - physiology | Motor Neurons - physiology | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cell Cycle Proteins - metabolism | S100 Proteins - metabolism | In Situ Nick-End Labeling - methods | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Immunohistochemistry - methods | Annexin A2 - genetics | Cell Death - physiology | Green Fluorescent Proteins - biosynthesis | Mice | Annexin A2 - metabolism | Age Factors | Phosphopyruvate Hydratase - metabolism | Cell Movement - physiology | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | Amino Acids - metabolism | Motor Neurons - cytology | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Membrane Proteins - metabolism | Bromodeoxyuridine - metabolism | Cell Differentiation - physiology | Pyramidal Tracts - physiology | Nerve Tissue Proteins - physiology | Neocortex - growth & development | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cell Count - methods | Neocortex - cytology | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Neurosciences | Neurons | Developmental biology | Stem cells | Studies | Brain | Ultrasonic imaging | Transcription factors | Hybridization | Neurogenesis | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 35, pp. 29579 - 29588
Mammalian target of rapamycin complex 2 (mTORC2) is a key activator of protein kinases that act downstream of insulin and growth factor signaling. Here we... 
TRANSCRIPTION FACTORS | DIABETES-MELLITUS | LIPID-METABOLISM | AKT/PKB | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER | MOTIF PHOSPHORYLATION | RICTOR | MICE | KINASE-B | INDUCED INSULIN-RESISTANCE | Phosphorylation - physiology | Humans | Glycogen Synthase Kinase 3 beta | GTPase-Activating Proteins - metabolism | Phosphoproteins - metabolism | Cholesterol - genetics | Proto-Oncogene Proteins c-akt - genetics | Fatty Acids - genetics | Forkhead Transcription Factors - metabolism | Insulin Resistance - physiology | Tumor Suppressor Proteins - genetics | Trans-Activators - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Insulin - genetics | Proto-Oncogene Proteins c-akt - metabolism | Fatty Acids - metabolism | Lipogenesis - physiology | Sterol Regulatory Element Binding Protein 1 - metabolism | Tumor Suppressor Proteins - metabolism | Liver - metabolism | Gene Expression Regulation - physiology | Glucose - genetics | Mice, Transgenic | Phosphoproteins - genetics | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Glycogen Synthase Kinase 3 - metabolism | Hep G2 Cells | Transcription Factors - metabolism | Insulin - metabolism | Animals | Glycogen Synthase Kinase 3 - genetics | Sterol Regulatory Element Binding Protein 1 - genetics | Adaptor Proteins, Signal Transducing - genetics | Glucose - metabolism | Trans-Activators - metabolism | Forkhead Box Protein O1 | Mice | GTPase-Activating Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cholesterol - biosynthesis | Index Medicus | mTOR Complex (mTORC) | Liver Metabolism | mTOR Complex 2 (mTORC2) | Akt | Metabolism | Lipogenesis | Insulin | Gluconeogenesis
Journal Article
Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 216 - U107
Our understanding of Alzheimer's disease pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model... 
AMYLOID BETA-PROTEIN | APP | MICROTUBULE-BINDING | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DOWN-SYNDROME | MOUSE MODEL | TAU | DYSFUNCTION | FIBROBLASTS | SENILE PLAQUES | Neurons - pathology | Coculture Techniques | Humans | Middle Aged | Amyloid beta-Peptides - secretion | tau Proteins - metabolism | Male | Phosphoproteins - metabolism | Endosomes - metabolism | Synapsins - metabolism | Alzheimer Disease - pathology | Cellular Reprogramming | Protease Inhibitors - pharmacology | Amyloid beta-Protein Precursor - secretion | Proteolysis | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Aged, 80 and over | Female | Neurons - metabolism | Phosphorylation - drug effects | Neurons - drug effects | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Astrocytes - cytology | Biomarkers - metabolism | Induced Pluripotent Stem Cells - pathology | Peptide Fragments - metabolism | Cells, Cultured | Peptide Fragments - secretion | Glycogen Synthase Kinase 3 - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Models, Biological | Alzheimer Disease - metabolism | Fibroblasts - cytology | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Enzyme Activation | Messenger RNA | Synthesis | Glycogen | Stem cells | Physiological aspects | Research | Alzheimer's disease | Proteins | Phosphorylation | Neurons | Efficiency | Genomes | Mutation | Alzheimers disease | Index Medicus
Journal Article
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 05/2012, Volume 112, Issue 9, pp. 1529 - 1537
In this study, the coordinated activation of ubiquitin-proteasome pathway (UPP), autophagy-lysosomal pathway (ALP), and mitochondrial remodeling including... 
Muscle protein degradation | Mitochondrial remodelling | Mitophagy | LC3b | MuRF1 | MAMMALIAN TARGET | mitochondrial remodelling | SPORT SCIENCES | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | muscle protein degradation | EXERCISE-INDUCED MUSCLE | COORDINATE ACTIVATION | FOXO TRANSCRIPTION FACTORS | HUMAN SKELETAL-MUSCLE | MITOCHONDRIAL FISSION | mitophagy | RESISTANCE EXERCISE | GENE-EXPRESSION | C2C12 MYOTUBES | Protein Kinases - metabolism | AMP-Activated Protein Kinases - metabolism | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Serine | Ubiquitin - metabolism | Male | Physical Endurance | Insulin - blood | Phosphoproteins - metabolism | Autophagy | Tripartite Motif Proteins | Quadriceps Muscle - enzymology | Time Factors | Forkhead Transcription Factors - metabolism | Mitochondrial Proteins - metabolism | Muscle Proteins - metabolism | Adult | Proto-Oncogene Proteins c-akt - metabolism | Quadriceps Muscle - pathology | Autophagy-Related Protein 12 | Mitochondrial Membrane Transport Proteins - metabolism | Mitochondria, Muscle - enzymology | Signal Transduction | Mitochondria, Muscle - pathology | Small Ubiquitin-Related Modifier Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | SKP Cullin F-Box Protein Ligases - metabolism | Energy Intake | GTP Phosphohydrolases - metabolism | Autophagy-Related Protein 5 | Energy Metabolism | Biopsy | Running | Proteasome Endopeptidase Complex - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Blood Glucose - metabolism | Forkhead Box Protein O3 | Proteins | Musculoskeletal system | Signal transduction | Physiology | Athletes | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2005, Volume 280, Issue 43, pp. 35983 - 35991
Journal Article
Cell Metabolism, ISSN 1550-4131, 11/2013, Volume 18, Issue 5, pp. 698 - 711
mRNA translation is thought to be the most energy-consuming process in the cell. Translation and energy metabolism are dysregulated in a variety of diseases... 
MAMMALIAN TARGET | RAPAMYCIN | BINDING PARTNER | SKELETAL-MUSCLE | DIFFERENTIAL TRANSLATION | PROTEIN-KINASE | ENDOCRINOLOGY & METABOLISM | GENOME-WIDE | MOTIF PHOSPHORYLATION | CELL-GROWTH | COMPLEX 2 | CELL BIOLOGY | Protein Biosynthesis | Ribosomal Protein S6 Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Mitochondrial Turnover | Adenosine Triphosphate - biosynthesis | Mechanistic Target of Rapamycin Complex 2 | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Mechanistic Target of Rapamycin Complex 1 | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Cell Nucleus - metabolism | Cell Respiration | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Autophagy - genetics | DNA, Mitochondrial - biosynthesis | Eukaryotic Initiation Factors - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Mitochondria - metabolism | Genome, Human - genetics | Transcription Factors - metabolism | Animals | Models, Biological | Mice | Adaptor Proteins, Signal Transducing - metabolism | RNA | Physiological aspects | Biosynthesis | Mitochondrial DNA | Diabetes | Binding proteins | Heart diseases | Genetic translation | Protein binding | Index Medicus
Journal Article
Science, ISSN 0036-8075, 10/2004, Volume 306, Issue 5695, pp. 457 - 461
Obesity contributes to the development of type 2 diabetes, but the underlying mechanisms are poorly understood. Using cell culture and mouse models, we show... 
Obesity | Phosphorylation | Receptors | Quantification | Liver | Lead | Insulin resistance | Type 2 diabetes mellitus | Insulin | Research Article | Type 1 diabetes mellitus | UNFOLDED PROTEIN RESPONSE | MESSENGER-RNA | ER STRESS | JNK | MULTIDISCIPLINARY SCIENCES | KINASE | IRE1 | RESISTANCE | TRANSCRIPTION FACTOR | XBP-1 | TRANSLATIONAL CONTROL | eIF-2 Kinase - metabolism | Endoplasmic Reticulum - metabolism | Homeostasis | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Phosphoproteins - metabolism | X-Box Binding Protein 1 | DNA-Binding Proteins - metabolism | Adipose Tissue - metabolism | Insulin Receptor Substrate Proteins | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | Liver - metabolism | Cells, Cultured | Insulin Resistance | Rats | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Regulatory Factor X Transcription Factors | Obesity - metabolism | Insulin - metabolism | Animals | Mitogen-Activated Protein Kinase 8 | Tunicamycin - pharmacology | Glucose - metabolism | Mice, Obese | Receptor, Insulin - metabolism | Mice | Mice, Inbred BALB C | Transcription Factors | Mutation | Mitogen-Activated Protein Kinases - metabolism | Type 2 diabetes | Causes of | Stress (Physiology) | Research | Endoplasmic reticulum | Cell culture | Enzymes | Medical research | Diabetes | Index Medicus
Journal Article