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Nucleic Acid Therapeutics, ISSN 2159-3337, 12/2016, Volume 26, Issue 6, pp. 381 - 391
New advances in oligonucleotide (ON) chemistry emerge continuously, and over the last few years, several aspects of ON delivery have been improved. However,... 
pLuc 705 | gymnotic delivery | oligonucleotide chemistries | splice-switching oligonucleotides | Reporter cell lines | delivery vectors | THERAPEUTICS | MEDICINE, RESEARCH & EXPERIMENTAL | CHEMISTRY, MEDICINAL | HUMAN-DISEASE | PENETRATING PEPTIDE | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-14-LABELED PHOSPHOROTHIOATE OLIGONUCLEOTIDE | PHARMACOKINETICS | SOLID FORMULATION | THERAPIES | reporter cell lines | ANTISENSE OLIGONUCLEOTIDES | INTRACELLULAR TRAFFICKING | Luciferases - metabolism | Lipopeptides - pharmacology | Humans | Hepatocytes - metabolism | Transfection - standards | Luciferases - genetics | Cell-Penetrating Peptides - pharmacology | Hepatocytes - cytology | Myoblasts - metabolism | Neuroglia - cytology | Lipids - pharmacology | Transfection - methods | Base Sequence | Myoblasts - cytology | Osteoblasts - cytology | Genes, Reporter | Cell Line | Genetic Vectors - chemistry | Genetic Vectors - metabolism | Organ Specificity | Phosphorothioate Oligonucleotides - chemical synthesis | Oligonucleotides - chemical synthesis | Oligonucleotides - metabolism | Animals | Neuroglia - metabolism | Phosphorothioate Oligonucleotides - metabolism | Mice | HeLa Cells | Osteoblasts - metabolism | Medical research | Biotechnology | Peptides | Laboratories | Nucleic acids | Switching | Biological activity | Nanoparticles | Oligomers | Organic chemistry | Chemistry | Acids | Cell lines | Phosphorothioate | Comparative analysis
Journal Article
Nature Biotechnology, ISSN 1087-0156, 09/2017, Volume 35, Issue 9, pp. 845 - 851
Journal Article
Chemistry & Biodiversity, ISSN 1612-1872, 09/2011, Volume 8, Issue 9, pp. 1616 - 1641
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 03/2017, Volume 45, Issue 5, pp. 2294 - 2306
Journal Article
Molecular Therapy, ISSN 1525-0016, 07/2017, Volume 25, Issue 7, pp. 1710 - 1717
Delivery technologies are required for realizing the clinical potential of molecular medicines. This work presents an alternative technology to preformulated... 
pharmacokinetics | biodistribution | palmitoyl | antisense gapmer oligonucleotides | albumin | MEDICINE, RESEARCH & EXPERIMENTAL | OLIGODEOXYNUCLEOTIDES | DESIGN | APOLIPOPROTEIN B-100 | MOUSE | PROTEIN-BINDING | BIODISTRIBUTION | DELIVERY | GENE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | LOCKED NUCLEIC-ACIDS | SIRNA | Oligonucleotides - chemistry | Palmitic Acid - metabolism | Myocardium - chemistry | Humans | Lung - chemistry | Half-Life | Delayed-Action Preparations - chemistry | Phosphorothioate Oligonucleotides - pharmacokinetics | Tissue Distribution | Myocardium - metabolism | Delayed-Action Preparations - pharmacokinetics | Female | Electrophoretic Mobility Shift Assay | Lung - metabolism | Phosphorothioate Oligonucleotides - chemistry | Serum Albumin, Human - chemistry | Palmitic Acid - chemistry | Liver - metabolism | Mice, Inbred C57BL | Oligonucleotides, Antisense - pharmacokinetics | Oligonucleotides, Antisense - chemistry | Liver - chemistry | Spleen - chemistry | Myristic Acid - metabolism | Oligonucleotides - metabolism | Animals | Spleen - metabolism | Mice | Myristic Acid - chemistry | Serum Albumin, Human - metabolism | Patents | Human serum albumin | Albumin | Antisense oligonucleotides | Palmitic acid | Experiments | Fatty acids | Blood circulation | Electrophoretic mobility | Phosphorothioate | Pharmacokinetics | Binding sites | Veins & arteries | Original
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