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Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 11/2010, Volume 49, Issue 47, pp. 10166 - 10178
Huntington’s disease (HD) is a currently incurable neurodegenerative disease caused by the expansion of a CAG trinucleotide repeat within the huntingtin (HTT)... 
RNA INTERFERENCE | NEURODEGENERATIVE DISEASE | NUCLEOSIDE ANALOGS | DISEASE GENE | LOCKED NUCLEIC-ACID | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SHOW IMPROVED POTENCY | MOUSE MODEL | APOLIPOPROTEIN-B | TRINUCLEOTIDE REPEAT | Oligonucleotides - genetics | Cell Line | Oligonucleotides, Antisense - pharmacology | Gene Expression - drug effects | Humans | Structure-Activity Relationship | Nerve Tissue Proteins - genetics | Huntingtin Protein | Oligonucleotides, Antisense - genetics | Nuclear Proteins - biosynthesis | Oligonucleotides - pharmacology | Oligonucleotides, Antisense - therapeutic use | Phosphorothioate Oligonucleotides - pharmacology | Alleles | Nerve Tissue Proteins - biosynthesis | Huntington Disease - genetics | Trinucleotide Repeat Expansion - drug effects | Huntington Disease - drug therapy | Nuclear Proteins - genetics | Ribonuclease H - metabolism | Huntington's chorea | Analysis | Oligonucleotides | Physiological aspects | Genetic aspects | Chemical properties | Gene expression | Structure | Huntington's Disease | antisense oligonucleotide | huntingtin | Locked nucleic acid (LNA) | allele-selective inhibition | CAG repeat | triplet repeat | Biological Sciences | Chemistry | Naturvetenskap | Biokemi och molekylärbiologi | Kemi | Biologiska vetenskaper | Biokemi | Biochemistry and Molecular Biology | Biochemistry | Natural Sciences
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 2, pp. 129 - 137
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 05/2017, Volume 45, Issue 9, pp. 5153 - 5169
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2, p. e0116703
Activation of TLR7 and TLR9 by endogenous RNA-or DNA-containing ligands, respectively, is thought to contribute to the complicated pathophysiology of systemic... 
PLASMACYTOID DENDRITIC CELLS | RNA | UNC93B1 | MULTIDISCIPLINARY SCIENCES | TOLL-LIKE RECEPTORS | TLR9 | CPG | IDENTIFICATION | TOLL-LIKE-RECEPTOR-7 | NUCLEIC-ACIDS | I INTERFERON | Leukocytes, Mononuclear - metabolism | Oligonucleotides - chemistry | Humans | Oligodeoxyribonucleotides - chemistry | Toll-Like Receptor 9 - genetics | Lupus Erythematosus, Systemic - metabolism | Male | Young Adult | Flow Cytometry | Oligonucleotides - pharmacology | Adult | Dendritic Cells - drug effects | Female | Guanine - chemistry | Interleukin-6 - metabolism | Dendritic Cells - metabolism | Toll-Like Receptor 7 - genetics | Leukocytes, Mononuclear - drug effects | Toll-Like Receptor 7 - metabolism | Cells, Cultured | Macrophages - metabolism | Animals | Macrophages - drug effects | Mice | Oligodeoxyribonucleotides - pharmacology | Toll-Like Receptor 9 - metabolism | Lupus | Autoimmunity | Purines | Immune response | Systemic lupus erythematosus | Dendritic cells | Disease susceptibility | Interferon | Imiquimod | Oligonucleotides | Antibodies | Macrophages | Guanine | Interleukin 6 | α-Interferon | Cell activation | Toll-like receptors | Peripheral blood mononuclear cells | Phosphorothioate | Inhibition | Deoxyribonucleic acid--DNA | CpG islands | Immune system | TLR7 protein | Secretion | Inflammation | T cell receptors | Ribonucleic acid--RNA | TLR9 protein | Chemical modification | Chronic conditions | Lymphocytes B | Ligands | Autoimmune diseases | Human behavior | Tetrads | Hygiene | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Journal Article