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1. Full Text Creatine biosynthesis and transport in health and disease
by Joncquel-Chevalier Curt, Marie and Voicu, Pia-Manuela and Fontaine, Monique and Dessein, Anne-Frédérique and Porchet, Nicole and Mention-Mulliez, Karine and Dobbelaere, Dries and Soto-Ares, Gustavo and Cheillan, David and Vamecq, Joseph
Biochimie, ISSN 0300-9084, 12/2015, Volume 119, pp. 146 - 165
GAMT | CRTR | SLC6A8 | AGAT | AMP activated protein kinase | Creatine | Secondary creatine disorders | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Transport Systems, Basic - genetics | Humans | Nerve Tissue Proteins - deficiency | Movement Disorders - diagnosis | Amidinotransferases - genetics | Intellectual Disability - metabolism | Biological Transport, Active | Gyrate Atrophy - enzymology | Amino Acid Metabolism, Inborn Errors - genetics | Intellectual Disability - enzymology | Brain Diseases, Metabolic, Inborn - genetics | Hyperammonemia - diagnosis | Hyperammonemia - genetics | Creatine - genetics | Urea Cycle Disorders, Inborn - metabolism | Creatine - biosynthesis | Gyrate Atrophy - genetics | Plasma Membrane Neurotransmitter Transport Proteins - metabolism | Guanidinoacetate N-Methyltransferase - metabolism | Amidinotransferases - metabolism | Plasma Membrane Neurotransmitter Transport Proteins - genetics | Language Development Disorders - enzymology | Urea Cycle Disorders, Inborn - diagnosis | Energy Metabolism | Urea Cycle Disorders, Inborn - enzymology | Movement Disorders - genetics | Mutation | Ornithine - deficiency | Amino Acid Transport Systems, Basic - metabolism | Amino Acid Metabolism, Inborn Errors - enzymology | S-Adenosylmethionine - metabolism | AMP-Activated Protein Kinases - metabolism | Hyperammonemia - metabolism | Developmental Disabilities - metabolism | Guanidinoacetate N-Methyltransferase - genetics | Ornithine - genetics | Developmental Disabilities - genetics | Language Development Disorders - metabolism | Brain Diseases, Metabolic, Inborn - enzymology | Brain Diseases, Metabolic, Inborn - diagnosis | Intellectual Disability - genetics | Amino Acid Metabolism, Inborn Errors - diagnosis | Amino Acid Metabolism, Inborn Errors - metabolism | Mental Retardation, X-Linked - genetics | Mental Retardation, X-Linked - enzymology | Developmental Disabilities - enzymology | Language Development Disorders - diagnosis | Mental Retardation, X-Linked - diagnosis | Movement Disorders - enzymology | Creatine - metabolism | Hyperammonemia - enzymology | Creatine - deficiency | Gyrate Atrophy - diagnosis | Developmental Disabilities - diagnosis | Speech Disorders - diagnosis | Plasma Membrane Neurotransmitter Transport Proteins - deficiency | Speech Disorders - metabolism | Amidinotransferases - deficiency | Brain Diseases, Metabolic, Inborn - metabolism | Language Development Disorders - genetics | Ornithine - metabolism | Gyrate Atrophy - metabolism | Prenatal Diagnosis | Speech Disorders - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Amino Acid Transport Systems, Basic - deficiency | Movement Disorders - metabolism | Animals | Urea Cycle Disorders, Inborn - genetics | Guanidinoacetate N-Methyltransferase - deficiency | Intellectual Disability - diagnosis | Movement Disorders - congenital | Speech Disorders - enzymology | Methylation | Mental Retardation, X-Linked - metabolism | Antioxidants | Phosphates | Algorithms | Animal behavior | Physiological aspects | GABA | Glycine | Phosphotransferases | Medical research | Medicine, Experimental | Protein kinases | Index Medicus | Life Sciences
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2. Full Text Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study
by Karacan, Ilker and Balamir, Ayse and Ugurlu, Serdal and Aydin, Asli Kirectepe and Everest, Elif and Zor, Seyit and Onen, Merve Ozkilinc and Dasdemir, Selcuk and Ozkaya, Ozan and Sozeri, Betul and Tufan, Abdurrahman and Yildirim, Deniz Gezgin and Yuksel, Selcuk and Ayaz, Nuray Aktay and Omeroglu, Rukiye Eker and Ozturk, Kubra and Cakan, Mustafa and Soylemezoglu, Oguz and Sahin, Sezgin and Barut, Kenan and Adrovic, Amra and Seyahi, Emire and Ozdogan, Huri and Kasapcopur, Ozgur and Turanli, Eda Tahir
Rheumatology international, ISSN 0172-8172, 05/2019, Volume 39, Issue 5, pp. 911 - 919
Life Sciences & Biomedicine | Rheumatology | Science & Technology | Genetic Testing | Agammaglobulinemia - genetics | Cytoskeletal Proteins - genetics | Humans | Middle Aged | Osteomyelitis - genetics | Anemia, Dyserythropoietic, Congenital - diagnosis | Child, Preschool | Pyrin - genetics | Agammaglobulinemia - diagnosis | Male | Mevalonate Kinase Deficiency - genetics | CARD Signaling Adaptor Proteins - genetics | Young Adult | Adult | Female | Adenosine Deaminase - deficiency | Immunologic Deficiency Syndromes - diagnosis | Child | Cryopyrin-Associated Periodic Syndromes - genetics | Adenosine Deaminase - genetics | Severe Combined Immunodeficiency - diagnosis | Anemia, Dyserythropoietic, Congenital - genetics | Familial Mediterranean Fever - genetics | Intercellular Signaling Peptides and Proteins - genetics | Nucleoside Transport Proteins - genetics | Phosphotransferases (Alcohol Group Acceptor) - genetics | Hereditary Autoinflammatory Diseases - diagnosis | Sequence Analysis, DNA | Mevalonate Kinase Deficiency - diagnosis | Severe Combined Immunodeficiency - genetics | Cryopyrin-Associated Periodic Syndromes - diagnosis | Osteomyelitis - diagnosis | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Immunologic Deficiency Syndromes - genetics | Familial Mediterranean Fever - diagnosis | High-Throughput Nucleotide Sequencing | Calcium-Binding Proteins - genetics | Hereditary Autoinflammatory Diseases - genetics | Medicine, Experimental | Genetic research | Medical research | Genes | Index Medicus
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3. Full Text Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
by Wan, Paul T.C and Garnett, Mathew J and Roe, S.Mark and Lee, Sharlene and Niculescu-Duvaz, Dan and Good, Valerie M and Project, Cancer Genome and Jones, C.Michael and Marshall, Christopher J and Springer, Caroline J and Barford, David and Marais, Richard and Cancer Genome Project
Cell (Cambridge), ISSN 0092-8674, 2004, Volume 116, Issue 6, pp. 855 - 867
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphotransferases - metabolism | Xenopus | NIH 3T3 Cells | Mitogen-Activated Protein Kinase Kinases - genetics | Phosphorylation | Molecular Conformation | MAP Kinase Kinase 1 | Oocytes | Mitogen-Activated Protein Kinase Kinases - metabolism | MAP Kinase Signaling System - genetics | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Phosphotransferases - genetics | Proto-Oncogene Proteins B-raf | Oncogenes - genetics | Allosteric Regulation - genetics | Proto-Oncogene Proteins c-raf - genetics | Catalytic Domain - genetics | Enzyme Inhibitors - pharmacology | Models, Molecular | Neoplasms - enzymology | Up-Regulation - genetics | Mutation - genetics | Proto-Oncogene Proteins c-raf - metabolism | Animals | Gene Expression Regulation, Enzymologic - genetics | Mitogen-Activated Protein Kinases - genetics | Mice | Proto-Oncogene Proteins c-raf - antagonists & inhibitors | Research | Gene mutations | Human genetics | Oncogenes | Index Medicus
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4. Full Text PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer
by Guigon, C.J and Zhao, L and Willingham, M.C and Cheng, S.-Y
Oncogene, ISSN 0950-9232, 01/2009, Volume 28, Issue 4, pp. 509 - 517
Mutations | Mouse model | Thyroid cancer | Pten | Carcinogenesis | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Non tumoral diseases. Target tissue resistance. Benign neoplasms | Malignant tumors | Thyroid. Thyroid axis (diseases) | Biological and medical sciences | Endocrinopathies | Cell physiology | Molecular and cellular biology | Medical sciences | Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes | Cyclin D1 - metabolism | Cell Proliferation | Chromosomes, Mammalian - genetics | Lung Neoplasms - metabolism | Caspase 3 - metabolism | Cell Survival - genetics | Apoptosis - genetics | Lung Neoplasms - pathology | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Proto-Oncogene Proteins c-akt - genetics | Thyroid Hormone Receptors beta - genetics | Neoplasm Metastasis | Lung Neoplasms - secondary | Forkhead Transcription Factors - metabolism | Mice, Mutant Strains | Caspase 3 - genetics | Proto-Oncogene Proteins c-akt - metabolism | Disease Models, Animal | Lung Neoplasms - genetics | PTEN Phosphohydrolase - genetics | Thyroid Hormone Receptors beta - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Neoplasm Invasiveness | PTEN Phosphohydrolase - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - genetics | Mice, Transgenic | Phosphotransferases (Alcohol Group Acceptor) - genetics | Signal Transduction - genetics | Forkhead Transcription Factors - genetics | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Phosphatidylinositol 3-Kinases - genetics | Carrier Proteins - genetics | Thyroid Neoplasms - genetics | Animals | Carrier Proteins - metabolism | Cyclin D1 - genetics | NF-kappa B - genetics | Mice | TOR Serine-Threonine Kinases | Chromosomes, Mammalian - metabolism | Enzyme Activation - genetics | Forkhead Box Protein O3 | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Development and progression | Tumor suppressor genes | Cellular signal transduction | Genetic aspects | Research | Health aspects | Risk factors | Genetics | Rodents | Thyroid diseases | Tumors | Index Medicus | thyroid cancer | mutations | carcinogenesis | mouse model
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5. Full Text Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers
by Ricarte-Filho, Julio C and Li, Sheng and Garcia-Rendueles, Maria E.R and Montero-Conde, Cristina and Voza, Francesca and Knauf, Jeffrey A and Heguy, Adriana and Viale, Agnes and Bogdanova, Tetyana and Thomas, Geraldine A and Mason, Christopher E and Fagin, James A
The Journal of clinical investigation, ISSN 0021-9738, 11/2013, Volume 123, Issue 11, pp. 4935 - 4944
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | NIH 3T3 Cells | Receptors, Thyrotropin - genetics | Proto-Oncogene Proteins c-ets - genetics | Humans | Child, Preschool | Molecular Sequence Data | Male | Young Adult | Neoplasms, Radiation-Induced - genetics | MAP Kinase Signaling System - genetics | Receptor, trkC - genetics | Oncogene Fusion | Base Sequence | Female | Child | PPAR gamma - genetics | Chernobyl Nuclear Accident | Ukraine | Repressor Proteins - genetics | Phosphotransferases (Alcohol Group Acceptor) - genetics | Thyroid Cancer, Papillary | Phosphatidylinositol 3-Kinases - genetics | Thyroid Neoplasms - genetics | Animals | Carcinoma, Papillary | Proto-Oncogene Proteins B-raf - genetics | Gene Rearrangement | Adolescent | Carcinoma - genetics | Mice | DNA, Neoplasm - genetics | Mutation | Cohort Studies | Proto-Oncogene Proteins c-ret - genetics | Thyroid cancer | Development and progression | Genetic aspects | Research | Identification and classification | Health aspects | Oncogenes | Proteins | Pediatrics | Genes | Genomes | Kinases | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | Abridged Index Medicus
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6. Full Text Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa
by Wei, Li Q and Xu, Wen Y and Deng, Zhu Y and Su, Zhen and Xue, Yongbiao and Wang, Tai
BMC genomics, ISSN 1471-2164, 05/2010, Volume 11, Issue 1, pp. 338 - 338
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Pollen - growth & development | Cell Cycle - genetics | Stress, Physiological - genetics | Down-Regulation | Genomics | RNA, Messenger - genetics | Oryza - physiology | Gene Expression Profiling | Ubiquitin - genetics | Transcription Factors - genetics | Oryza - enzymology | Arabidopsis - genetics | Proteasome Endopeptidase Complex - genetics | Oryza - growth & development | Oryza - genetics | Genes, Plant - genetics | Germination - genetics | Pollen - genetics | Plant Growth Regulators - genetics | Phosphotransferases - genetics | Pollen - physiology | Regulatory Elements, Transcriptional - genetics | Usage | Transcription factors | DNA microarrays | Physiological aspects | Genetic aspects | Research | Gene expression | Rice | Proteins | Studies | Sperm | Technological change | Cell division | Pollen | Genomes | Software | Biology | Experiments | DNA repair | Index Medicus
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7. Full Text MASTL overexpression promotes chromosome instability and metastasis in breast cancer
by Rogers, Samuel and McCloy, Rachael A and Parker, Benjamin L and Gallego-Ortega, David and Law, Andrew M. K and Chin, Venessa T and Conway, James R. W and Fey, Dirk and Millar, Ewan K. A and O’Toole, Sandra and Deng, Niantao and Swarbrick, Alexander and Chastain, Paul D and Cesare, Anthony J and Timpson, Paul and Caldon, C. Elizabeth and Croucher, David R and James, David E and Watkins, D. Neil and Burgess, Andrew
Oncogene, ISSN 0950-9232, 08/2018, Volume 37, Issue 33, pp. 4518 - 4533
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Proliferation - genetics | Microtubule-Associated Proteins - genetics | Humans | Protein-Serine-Threonine Kinases - genetics | Signal Transduction - genetics | Epithelial-Mesenchymal Transition - genetics | Mice, SCID | Proto-Oncogene Proteins c-akt - genetics | Phosphatidylinositol 3-Kinases - genetics | Chromosomal Instability - genetics | Animals | Breast Neoplasms - genetics | MAP Kinase Signaling System - genetics | TOR Serine-Threonine Kinases - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | DNA Damage - genetics | Cell Cycle Checkpoints - genetics | Female | Mice, Inbred NOD | Mice | Actin Cytoskeleton - genetics | Care and treatment | Chromosome abnormalities | Development and progression | Breast cancer | Genetic aspects | Gene expression | Health aspects | Phosphotransferases | Risk factors | TOR protein | Cell proliferation | Contact inhibition | Cell culture | Mesenchyme | Interphase | Mitosis | Lung cancer | DNA damage | Desmosomes | AKT protein | Metastasis | Cytokinesis | Kinases | 1-Phosphatidylinositol 3-kinase | Metastases | Signal transduction | Actin | Micronuclei | Cytoskeleton | Mathematical models | Cell migration | Index Medicus
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