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Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1492 - 1499
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 04/2012, Volume 158, Issue 4, pp. 203 - 210
The cost of the lignocellulose-hydrolyzing enzymes used in the saccharification process of ethanol production from biomass accounts for a relatively high... 
Bioethanol | Biomass | Lignocellulose | Cell surface display | XYLANASE | ACID | FUEL ETHANOL | CELLULOSIC BIOMASS | COFERMENTATION | LIQUID HOT-WATER | PRETREATMENT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LIGNOCELLULOSIC HYDROLYSATE | FERMENTATION | EXPRESSION | Aldehyde Reductase - genetics | Xylans - metabolism | D-Xylulose Reductase - genetics | Oryza - metabolism | Saccharomyces cerevisiae - genetics | Endo-1,4-beta Xylanases - genetics | Polysaccharides - genetics | Glucuronates - metabolism | D-Xylulose Reductase - metabolism | Pichia - enzymology | Xylose - genetics | Saccharomyces cerevisiae - metabolism | Pichia - metabolism | Lignin - metabolism | beta-Glucosidase - genetics | Glucuronates - genetics | Escherichia coli - metabolism | beta-Glucosidase - metabolism | Aldehyde Reductase - metabolism | Endo-1,4-beta Xylanases - metabolism | Metabolic Engineering - methods | Xylose - metabolism | Ethanol - metabolism | Phosphotransferases (Alcohol Group Acceptor) - genetics | Trichoderma - genetics | Oligosaccharides - metabolism | Saccharomyces cerevisiae Proteins - genetics | Fermentation | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Polysaccharides - metabolism | Hydrolysis | Xylans - genetics | Aspergillus oryzae - genetics | Escherichia coli - genetics | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae - enzymology | Lignin - genetics | Aspergillus oryzae - metabolism | Oligosaccharides - genetics | Trichoderma - metabolism | Xylitol | Enzymes | Alcohol, Denatured | Alcohol | Production processes | Sugars | Production data | Rice | Alcohols | Monosaccharides | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2010, Volume 39, Issue 6, pp. 839 - 850
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2009, Volume 5, Issue 8, pp. e1000559 - e1000559
The intraerythrocytic parasite Plasmodium-the causative agent of malaria-produces an inorganic crystal called hemozoin (Hz) during the heme detoxification... 
APOPTOSIS | INNATE IMMUNE RECEPTORS | INTERLEUKIN-1-BETA | MACROPHAGES | CASPASE-1 INFLAMMASOME | MICROBIOLOGY | KAPPA-B | NALP3 INFLAMMASOME | RESPONSES | VIROLOGY | IN-VIVO | MICE | PARASITOLOGY | Potassium - metabolism | Reactive Oxygen Species - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Protein-Tyrosine Kinases - metabolism | Humans | Caspase 1 - metabolism | Male | Caspase 1 - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Hemeproteins - immunology | Signal Transduction - immunology | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | src-Family Kinases - metabolism | Cytoskeletal Proteins - metabolism | Female | Interleukin-1beta - biosynthesis | Phosphorylation - immunology | Malaria - metabolism | Syk Kinase | Carrier Proteins - immunology | Disease Models, Animal | Neutrophil Infiltration - immunology | Calcium-Binding Proteins - metabolism | Carrier Proteins - physiology | Apoptosis Regulatory Proteins - immunology | Plasmodium chabaudi - chemistry | Hemeproteins - metabolism | Malaria - immunology | Mice, Inbred C57BL | Cathepsin B - metabolism | Inflammation - immunology | Plasmodium chabaudi - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | CARD Signaling Adaptor Proteins | Malaria - parasitology | Proteomics | HSP90 Heat-Shock Proteins - metabolism | Hemeproteins - physiology | Mice | Phagocytosis | Hostages | Inflammation | Malaria | Phosphotransferases | Index Medicus | Medical research | Salmonella | Phosphorylation | Lipids | Parasites | Experiments | Fever | Tropical diseases
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 131, Issue 2, pp. 501 - 511.e1
Background Sphingosine-1-phosphate (S1P), which is produced by 2 sphingosine kinase (SphK) isoenzymes, SphK1 and SphK2, has been implicated in IgE-mediated... 
Allergy and Immunology | airway hyperresponsiveness | asthma | nuclear factor κB | mast cells | sphingosine kinase | Sphingosine-1-phosphate | IMMUNITY | FC-EPSILON-RI | nuclear factor kappa B | FACTOR-KAPPA-B | IMMUNOLOGY | MULTIPLE FEATURES | REGULATES MUCIN PRODUCTION | RESPONSES | CYTOKINE PRODUCTION | ALLERGY | GENE-EXPRESSION | MICE | Tumor Necrosis Factor-alpha - metabolism | Lysophospholipids - metabolism | Asthma - metabolism | Bronchial Hyperreactivity - drug therapy | Humans | Goblet Cells - drug effects | NF-kappa B - metabolism | Amino Alcohols - pharmacology | Interferon-gamma - metabolism | Interleukins - metabolism | Inflammation - metabolism | Inflammation - drug therapy | Methacholine Chloride - pharmacology | Mast Cells - metabolism | Bronchial Hyperreactivity - metabolism | Female | Chemokine CCL2 - metabolism | Hyperplasia - drug therapy | Lung - metabolism | Sphingosine - metabolism | Hyperplasia - metabolism | Asthma - enzymology | Immunoglobulin E - metabolism | Mice, Inbred C57BL | Cells, Cultured | Ovalbumin - pharmacology | Asthma - drug therapy | Goblet Cells - metabolism | Mast Cells - drug effects | Asthma - chemically induced | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Bronchial Hyperreactivity - enzymology | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Bronchial Hyperreactivity - pathology | Sphingosine - analogs & derivatives | Animals | Lung - drug effects | Mice | Bronchoalveolar Lavage Fluid - chemistry | Phosphates | Medical colleges | Isoenzymes | Analysis | Sphingosine | Inflammation | Asthma | Studies | Cytokines | Lungs | Rodents | Kinases | Laboratory animals | Allergies | Index Medicus | Abridged Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2014, Volume 20, Issue 3, pp. 526 - 540
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2009, Volume 296, Issue 6, pp. 1248 - 1257
Loss of muscle mass occurs in a variety of diseases, including cancer, chronic heart failure, aquired immunodeficiency syndrome, diabetes, and renal failure,... 
Myostatin | Muscle atrophy | Akt | Hypertrophy | MYOBLAST DIFFERENTIATION | PHYSIOLOGY | hypertrophy | MYOSTATIN GENE | UBIQUITIN LIGASES | myostatin | CELL BIOLOGY | SKELETAL-MUSCLE | IN-VIVO | GROWTH | ATROPHY INVOLVE | MICE | muscle atrophy | EXPRESSION | Phosphorylation | Receptors, Transforming Growth Factor beta - genetics | Age Factors | Muscle Denervation | Male | Muscle, Skeletal - innervation | Muscle, Skeletal - metabolism | Smad3 Protein - metabolism | Proto-Oncogene Proteins c-akt - genetics | Tripartite Motif Proteins | Muscle Development | Muscular Atrophy - physiopathology | Transfection | RNA Interference | Muscle Proteins - metabolism | Cell Differentiation | Muscular Atrophy - prevention & control | Myostatin - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Muscular Atrophy - metabolism | Signal Transduction | Muscular Atrophy - pathology | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Smad2 Protein - metabolism | Ubiquitin-Protein Ligases - metabolism | Mice, Transgenic | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Animals | Carrier Proteins - metabolism | Receptors, Transforming Growth Factor beta - metabolism | Sciatic Nerve - surgery | Muscle, Skeletal - physiopathology | Mice | TOR Serine-Threonine Kinases | Muscle, Skeletal - pathology | Mutation | Transforming Growth Factor beta - metabolism | RNA, Small Interfering - metabolism | Proteins | Signal transduction | Musculoskeletal system | Adults | Cells | Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 06/2012, Volume 15, Issue 6, pp. 813 - 826
Immune cells are somewhat unique in that activation responses can alter quantitative phenotypes upwards of 100,000-fold. To date little is known about the... 
PROTEIN | GENE | CELL ACTIVATION | GLUTATHIONE | MURINE MACROPHAGES | TRANSCRIPTION | ENDOCRINOLOGY & METABOLISM | RECEPTOR | BINDING-ACTIVITY | DIFFERENTIATION | INFLAMMATORY RESPONSE | CELL BIOLOGY | Tumor Necrosis Factor-alpha - metabolism | Cell Polarity | Transcription Factors - chemistry | Endotoxemia - enzymology | Phosphotransferases (Alcohol Group Acceptor) - chemistry | Humans | Tumor Necrosis Factor-alpha - genetics | Male | Endotoxemia - immunology | Interleukin-6 - metabolism | Macrophages - immunology | Macrophages - physiology | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Double-Blind Method | Interleukin-6 - genetics | Down-Regulation | Mice, Inbred C57BL | Tumor Necrosis Factor-alpha - secretion | Carbohydrate Metabolism | Models, Molecular | Phosphotransferases (Alcohol Group Acceptor) - genetics | Transcription Factors - genetics | Interleukin-6 - secretion | Macrophages - enzymology | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Macrophages - metabolism | Phenotype | Animals | Energy Metabolism | Lipopolysaccharides - pharmacology | Glucose - metabolism | Mice | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Phosphates | Glucose metabolism | Medical colleges | Orphans | Physiological aspects | Glucose | Macrophages | Phosphotransferases | Dextrose | Sugars | Monosaccharides | Index Medicus | Adaptations | Carbohydrates | Polarization | Cell activation | Immunomodulation | Pentose phosphate pathway | Lipopolysaccharides
Journal Article
Plant Physiology and Biochemistry, ISSN 0981-9428, 12/2013, Volume 73, pp. 7 - 15
Journal Article
Nature Immunology, ISSN 1529-2908, 12/2013, Volume 14, Issue 12, pp. 1247 - 1255
The inflammasome adaptor ASC contributes to innate immunity through the activation of caspase-1. Here we found that signaling pathways dependent on the kinases... 
LISTERIA-MONOCYTOGENES | AIM2 INFLAMMASOME | PROTEIN | INNATE IMMUNE-RESPONSES | MACROPHAGES | KINASE | HOST-DEFENSE | NLRP3 INFLAMMASOME | IMMUNOLOGY | CASPASE-1 ACTIVATION | VIRAL-INFECTION | Interleukin-18 - immunology | Inflammasomes - metabolism | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Protein-Tyrosine Kinases - metabolism | Dendritic Cells - immunology | Humans | JNK Mitogen-Activated Protein Kinases - immunology | Caspase 1 - metabolism | Immunoblotting | Intracellular Signaling Peptides and Proteins - metabolism | RNA Interference | Bone Marrow Cells - immunology | Phosphorylation - immunology | JNK Mitogen-Activated Protein Kinases - genetics | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Carrier Proteins - immunology | DNA-Binding Proteins | Tyrosine - immunology | Mice, Knockout | Macrophages - metabolism | Tyrosine - metabolism | Lipopolysaccharides - pharmacology | Mice | Interleukin-18 - metabolism | Intracellular Signaling Peptides and Proteins - immunology | JNK Mitogen-Activated Protein Kinases - metabolism | Caspase 1 - immunology | Protein-Tyrosine Kinases - immunology | Protein-Tyrosine Kinases - genetics | HEK293 Cells | Cytoskeletal Proteins - metabolism | Female | Nuclear Proteins - genetics | Dendritic Cells - metabolism | Macrophages - immunology | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Nuclear Proteins - immunology | Inflammasomes - genetics | Carrier Proteins - genetics | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | CARD Signaling Adaptor Proteins | Inflammasomes - immunology | Macrophages - drug effects | Nigericin - pharmacology | Bone Marrow Cells - metabolism | Tyrosine - genetics | Cellular signal transduction | Inflammation | Genetic aspects | Research | Properties | Phosphotransferases | Index Medicus
Journal Article