X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (968) 968
Publication (71) 71
Book Review (5) 5
Conference Proceeding (2) 2
Book Chapter (1) 1
Data Set (1) 1
Paper (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
phthalimides - pharmacology (589) 589
animals (384) 384
index medicus (324) 324
humans (288) 288
phthalimides - chemistry (229) 229
chemistry, medicinal (219) 219
pharmacology & pharmacy (185) 185
structure-activity relationship (185) 185
male (167) 167
mice (165) 165
phthalimides - chemical synthesis (162) 162
phthalimide (151) 151
rats (135) 135
biochemistry & molecular biology (123) 123
plant sciences (113) 113
indoleacetic acids - metabolism (102) 102
molecular structure (89) 89
female (85) 85
derivatives (84) 84
thalidomide (80) 80
chemistry, organic (76) 76
phthalimides (76) 76
isoindoles (73) 73
plants (70) 70
auxins (68) 68
dose-response relationship, drug (66) 66
enzyme inhibitors - pharmacology (63) 63
inhibitors (61) 61
analysis (60) 60
chemistry, multidisciplinary (59) 59
research (59) 59
expression (58) 58
auxin (57) 57
design (56) 56
models, molecular (56) 56
biological transport - drug effects (55) 55
in vitro techniques (55) 55
plant roots - growth & development (55) 55
cell biology (54) 54
drug design (53) 53
phthalimides - metabolism (52) 52
arabidopsis (47) 47
indoleacetic acids - pharmacology (47) 47
analogs (46) 46
cancer (46) 46
growth (46) 46
mutation (46) 46
plant growth regulators - pharmacology (46) 46
binding sites (44) 44
chemistry (44) 44
arabidopsis - genetics (43) 43
plant roots - drug effects (43) 43
antineoplastic agents - pharmacology (42) 42
cell line, tumor (42) 42
indoleacetic acids - antagonists & inhibitors (40) 40
tryptophan - analogs & derivatives (40) 40
arabidopsis - growth & development (39) 39
cell line (39) 39
cells, cultured (39) 39
kinetics (39) 39
phthalimides - therapeutic use (38) 38
phthalimides - toxicity (38) 38
proteins (38) 38
seedlings (37) 37
article (36) 36
binding (36) 36
in-vitro (36) 36
time factors (36) 36
acid (35) 35
arabidopsis - metabolism (35) 35
thalidomide - analogs & derivatives (35) 35
thalidomide - pharmacology (35) 35
cells (34) 34
ligands (33) 33
physiological aspects (33) 33
transport (33) 33
gene expression regulation, plant - drug effects (32) 32
gravitropism (32) 32
heart rate - drug effects (32) 32
phthalimide derivatives (32) 32
plant roots (32) 32
rats, sprague-dawley (32) 32
arabidopsis - drug effects (31) 31
cell proliferation - drug effects (31) 31
docking (31) 31
guinea pigs (31) 31
inhibition (31) 31
oncology (31) 31
protein (31) 31
arabidopsis proteins - genetics (30) 30
dogs (30) 30
herbicides - pharmacology (30) 30
plant roots - metabolism (30) 30
thalidomide - chemistry (30) 30
tumor cells, cultured (30) 30
cell survival - drug effects (29) 29
synthesis (29) 29
antineoplastic agents - chemistry (28) 28
arabidopsis proteins - metabolism (28) 28
discovery (28) 28
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (911) 911
German (18) 18
Japanese (18) 18
Chinese (12) 12
Polish (5) 5
Russian (3) 3
French (2) 2
Italian (2) 2
Croatian (1) 1
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Neuroscience, ISSN 0270-6474, 11/2011, Volume 31, Issue 46, pp. 16619 - 16636
DNA methylation is an epigenetic mechanism for gene silencing engaged by DNA methyltransferase (Dnmt)-catalyzed methyl group transfer to cytosine residues in... 
SUBCELLULAR REDISTRIBUTION | PERMEABILITY TRANSITION PORE | WESTERN-BLOT-ANALYSIS | DE-NOVO | SPINAL-CORD | CENTRAL-NERVOUS-SYSTEM | AMYOTROPHIC-LATERAL-SCLEROSIS | METHYLTRANSFERASES DNMT3A | CEREBRAL-ISCHEMIA | NEUROSCIENCES | TRANSGENIC MICE | Propionates - pharmacology | Amyloid Precursor Protein Secretases - genetics | Cytosine - analogs & derivatives | RNA, Small Interfering - genetics | Central Nervous System - metabolism | Age Factors | Apoptosis - drug effects | 5-Methylcytosine - analogs & derivatives | Humans | Caspase 3 - metabolism | Gene Expression Regulation, Developmental - genetics | Apoptosis - genetics | Green Fluorescent Proteins - genetics | Aspartic Acid Endopeptidases - genetics | Central Nervous System - growth & development | Transfection | Epigenomics - methods | Cytosine - metabolism | Tryptophan - analogs & derivatives | Indoles - pharmacology | Superoxide Dismutase - metabolism | Disease Models, Animal | Motor Neurons - physiology | DNA (Cytosine-5-)-Methyltransferase 1 | Enzyme Inhibitors - pharmacology | Gene Expression Regulation, Developmental - drug effects | Sciatic Neuropathy - pathology | Mice, Transgenic | Up-Regulation - genetics | DNA Methylation - genetics | Mutation - genetics | Up-Regulation - drug effects | DNA (Cytosine-5-)-Methyltransferases - genetics | Amyloid Precursor Protein Secretases - metabolism | Amyotrophic Lateral Sclerosis - pathology | Animals | Phthalimides | Aspartic Acid Endopeptidases - metabolism | Mice | Camptothecin - pharmacology | Sciatic Neuropathy - metabolism | Cell Line, Transformed | RNA, Small Interfering - metabolism
Journal Article
Plant Physiology, ISSN 0032-0889, 10/2008, Volume 148, Issue 2, pp. 881 - 893
Journal Article
Targeted Oncology, ISSN 1776-2596, 12/2015, Volume 10, Issue 4, pp. 523 - 533
After extensive research on radiochemotherapy, 5-year survival rates of children with high risk neuroblastoma still do not exceed 50%, owing to adverse... 
Screening system | Medicine & Public Health | F-box proteins | DNA methyltransferase inhibitors | Oncology | Neuroblastoma | Doxorubicin | Biomedicine general | RNA-interference | APOPTOSIS | TUMOR-SUPPRESSOR GENES | SENSITIVITY | BREAST-CANCER CELLS | GENOMICS | ONCOLOGY | METHYLTRANSFERASES | DRUGS | LEUKEMIA | EXPRESSION | RNA, Small Interfering - genetics | DNA Modification Methylases - antagonists & inhibitors | Humans | Aminoquinolines - administration & dosage | Neuroblastoma - therapy | Tryptophan - administration & dosage | Molecular Targeted Therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Enzyme Inhibitors - administration & dosage | Phthalimides - pharmacology | Phthalimides - administration & dosage | Tryptophan - analogs & derivatives | HEK293 Cells | Naphthoquinones - administration & dosage | Aminoquinolines - pharmacology | Neuroblastoma - pathology | Doxorubicin - administration & dosage | Pyrimidines - administration & dosage | Neuroblastoma - genetics | Enzyme Inhibitors - pharmacology | Naphthoquinones - pharmacology | Pyrimidines - pharmacology | Drug Synergism | Neuroblastoma - drug therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Tryptophan - pharmacology | RNA, Small Interfering - administration & dosage | DNA Methylation - drug effects | F-Box Proteins - genetics | Doxorubicin - pharmacology | Anthracyclines | Chromatin | RNA | Transferases | DNA | Cellular signal transduction | Methylation | Health aspects
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 04/2006, Volume 6, Issue 8, pp. 771 - 785
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 1998, Volume 5, Issue 12, pp. 1062 - 1075
It has been suggested that overexpression of the Bcl-2 oncoprotein in human cancer cells contributes to their resistance to apoptosis induced by chemotherapy,... 
Bcl-2 | p27 | Human cancers | Anticancer drugs | Drug resistance | p21 | Proteasome inhibitors | Apoptosis | HUMAN LEUKEMIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | proteasome inhibitors | DRUG-RESISTANCE | KAPPA-B | CLEAVAGE | anticancer drugs | ICE-LIKE PROTEASE | CELL BIOLOGY | PROGRAMMED CELL-DEATH | ICE/CED-3 PROTEASE | RETINOBLASTOMA PROTEIN | human cancers | drug resistance | FLOW-CYTOMETRY | THYMOCYTE APOPTOSIS | Fibroblasts - enzymology | Jurkat Cells - cytology | Nucleic Acid Synthesis Inhibitors - pharmacology | Apoptosis - drug effects | Chymotrypsin - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Multienzyme Complexes - metabolism | Dimethyl Sulfoxide - pharmacology | Proteasome Endopeptidase Complex | Jurkat Cells - chemistry | Solvents - pharmacology | Phthalimides - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | Cysteine Endopeptidases - metabolism | Cyclins - metabolism | Amino Acid Chloromethyl Ketones - pharmacology | Dipeptides - metabolism | Cell Line, Transformed - cytology | Fibroblasts - chemistry | Cyclins - antagonists & inhibitors | Cyclin-Dependent Kinase Inhibitor p21 | Dipeptides - pharmacology | Etoposide - pharmacology | Microtubule-Associated Proteins - antagonists & inhibitors | Simian virus 40 - genetics | Caspase Inhibitors | Poly(ADP-ribose) Polymerase Inhibitors | Cyclin-Dependent Kinase Inhibitor p27 | Cell Line, Transformed - chemistry | HL-60 Cells - chemistry | Poly Adenosine Diphosphate Ribose - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Cell Line, Transformed - enzymology | HL-60 Cells - cytology | Gene Expression Regulation, Viral | Cysteine Proteinase Inhibitors - pharmacology | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Fibroblasts - cytology | Jurkat Cells - enzymology | Apoptosis - physiology | HL-60 Cells - enzymology | Cell Cycle Proteins | Tumor Suppressor Proteins
Journal Article
Journal Article
Functional & Integrative Genomics, ISSN 1438-793X, 11/2016, Volume 16, Issue 6, pp. 595 - 617
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2015, Volume 92, pp. 738 - 749
Journal Article
Journal Article
Journal Article
Molecular Oncology, ISSN 1574-7891, 06/2017, Volume 11, Issue 6, pp. 612 - 627
The transcription factor p53 plays a crucial role in cancer development and dissemination, and thus, p53‐targeted therapies are among the most encouraging... 
anticancer therapy | MDM2 | tryptophanol‐derived oxazoloisoindolinone | small‐molecule | MDMX | p53 | Small-molecule | Tryptophanol-derived oxazoloisoindolinone | Anticancer therapy | P53 | ACTIVATION | METASTASIS | ANGIOGENESIS | P53 PATHWAY | CANCER-THERAPY | ONCOLOGY | MUTANT P53 | small-molecule | PROTEINS | CARCINOMA | EXPRESSION | tryptophanol-derived oxazoloisoindolinone | Isoindoles - chemistry | Up-Regulation | Rats, Wistar | Tumor Suppressor Protein p53 - antagonists & inhibitors | Apoptosis - drug effects | Humans | Phthalimides - chemistry | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Oxazoles - chemistry | Phthalimides - pharmacology | MCF-7 Cells | Antineoplastic Agents - pharmacology | Isoindoles - pharmacology | Proto-Oncogene Proteins c-mdm2 - antagonists & inhibitors | Proto-Oncogene Proteins c-mdm2 - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | HCT116 Cells | Tumor Suppressor Protein p53 - metabolism | Angiogenesis Inhibitors - pharmacology | Rats | Nuclear Proteins - metabolism | Antineoplastic Agents - chemistry | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Animals | Nuclear Proteins - antagonists & inhibitors | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Oxazoles - pharmacology | Angiogenesis Inhibitors - chemistry | Index Medicus
Journal Article