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1. Full Text Isoflavones: estrogenic activity, biological effect and bioavailability
by Vitale, Daniela Cristina and Piazza, Cateno and Melilli, Barbara and Drago, Filippo and Salomone, Salvatore
European Journal of Drug Metabolism and Pharmacokinetics, ISSN 0378-7966, 3/2013, Volume 38, Issue 1, pp. 15 - 25
Isoflavones are phytoestrogens with potent estrogenic activity; genistein, daidzein and glycitein are the most active isoflavones found in soy beans.... 
Phytoestrogens | Human Physiology | Genistein | Medical Biochemistry | Bioavailability | Biomedicine | Pharmacy | Pharmaceutical Sciences/Technology | Biological effect | Daidzein | Pharmacology/Toxicology | Estrogenic activity | Isoflavones | SOYBEAN ISOFLAVONES | SMALL-INTESTINE | IN-VITRO | BONE LOSS | ORAL BIOAVAILABILITY | PROSTATE-CANCER | DOUBLE-BLIND | SOY ISOFLAVONES | PHYTO-ESTROGENS | PHARMACOLOGY & PHARMACY | DIETARY PHYTOESTROGENS | Drug Administration Routes | Humans | Isoflavones - pharmacokinetics | Isoflavones - pharmacology | Phytoestrogens - chemistry | Solubility | Phytoestrogens - pharmacokinetics | Biological Availability | Isoflavones - chemistry | Permeability | Chemistry, Pharmaceutical | Intestinal Absorption | Tissue Distribution | Animals | Biotransformation | Drug Design | Drug Compounding | Dosage Forms | Phytoestrogens - administration & dosage | Isoflavones - administration & dosage | Phytoestrogens - pharmacology
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2. Phytoestrogens and health
by Hughes, I. A and Food Standards Agency (Great Britain) and Woods, H. Frank and Great Britain. Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment
2003, 441
Phytoestrogens -- Health aspects | Phytoestrogens -- Physiological effect
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3. Full Text Soy, phytoestrogens and their impact on reproductive health
by Cederroth, Christopher Robin and Zimmermann, Céline and Nef, Serge
Molecular and Cellular Endocrinology, ISSN 0303-7207, 05/2012, Volume 355, Issue 2, pp. 192 - 200
There is growing interest in the potential health threats posed by endocrine-disrupting chemicals (EDCs) to the reproductive system. Soybean is the most... 
Phytoestrogens | Reproduction | Endocrine disruptor | Soy | Fertility | Isoflavones | MARMOSET MONKEYS | NEONATAL EXPOSURE | INHIBIT LIPID-ACCUMULATION | ISOFLAVONE INTAKE | CELL BIOLOGY | OOCYTE NEST BREAKDOWN | IN-VITRO | PERINATAL EXPOSURE | HORMONE CONCENTRATIONS | ENDOCRINOLOGY & METABOLISM | PHYTO-ESTROGENS | DIETARY PHYTOESTROGENS | Reproductive Health | Humans | Isoflavones - biosynthesis | Isoflavones - pharmacology | Isoflavones - metabolism | Reproductive Physiological Phenomena - drug effects | Soybeans - metabolism | Soybeans - chemistry | Absorption | Animals | Endocrine Disruptors - pharmacology | Phytoestrogens - metabolism | Phytoestrogens - pharmacology | Endocrine disruptors | Estrogen
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4. Full Text Phytoestrogens and their effects
by Sirotkin, Alexander V and Harrath, Abdel Halim
European Journal of Pharmacology, ISSN 0014-2999, 10/2014, Volume 741, Issue 1, pp. 230 - 236
The chemical structure, classification, source, metabolism, physiological and health effects of plant phytoestrogens and mechanisms of their action are... 
Phytoestrogen | Nervous system | Reproduction | Bone | Cardiovascular | Immune system | SOY INFANT FORMULA | SIGNALING PATHWAYS | ALZHEIMERS-DISEASE | MENOPAUSAL SYMPTOMS | CELL-PROLIFERATION | HORMONE REPLACEMENT THERAPY | EFFERENT DUCTULES | ISOFLAVONES | CARDIOVASCULAR-DISEASE | PHARMACOLOGY & PHARMACY | PARKINSONS-DISEASE | Plant Preparations - chemistry | Receptors, Estrogen - metabolism | Cardiovascular Diseases - metabolism | Cardiovascular Diseases - drug therapy | Humans | Phytoestrogens - chemistry | Osteoporosis - drug therapy | Treatment Outcome | Breast Neoplasms - drug therapy | Phytoestrogens - therapeutic use | Breast Neoplasms - metabolism | Plant Preparations - metabolism | Animals | Osteoporosis - metabolism | Plant Preparations - therapeutic use | Female | Phytoestrogens - metabolism | Physiological aspects | Osteoporosis | Zoology | Estrogen | Isoflavones
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5. Full Text Endocrine Disrupters: A Review of Some Sources, Effects, and Mechanisms of Actions on Behaviour and Neuroendocrine Systems
by Frye, C and Bo, E and Calamandrei, G and Calzà, L and Dessì‐Fulgheri, F and Fernández, M and Fusani, L and Kah, O and Kajta, M and Le Page, Y and Patisaul, H. B and Venerosi, A and Wojtowicz, A. K and Panzica, G. C
Journal of Neuroendocrinology, ISSN 0953-8194, 01/2012, Volume 24, Issue 1, pp. 144 - 159
Some environmental contaminants interact with hormones and may exert adverse consequences as a result of their actions as endocrine disrupting chemicals... 
retinoid X receptor | tributyltin | xenoestrogens | diethylstilbestrol | dichloro diphenyl trichloroethane | ethinylestradiol | the peroxisome proliferator‐activated receptor | methoxychlor | bisphenol A | biocides | phytoestrogens | aryl hydrocarbon receptor | Ethinylestradiol | Aryl hydrocarbon receptor | Bisphenol A | Phytoestrogens | Retinoid X receptor | Xenoestrogens | The peroxisome proliferator-activated receptor | Diethylstilbestrol | Tributyltin | Methoxychlor | Biocides | Dichloro diphenyl trichloroethane | PARVOCELLULAR VASOTOCIN SYSTEM | RELEVANT NEURAL CIRCUITS | FUNCTIONAL AROMATASE GENE | the peroxisome proliferator-activated receptor | JAPANESE-QUAIL EMBRYOS | FEMALE SEXUAL-BEHAVIOR | NEUROSCIENCES | COMPARATIVE DEVELOPMENTAL NEUROTOXICITY | ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | ENVIRONMENTAL-LIKE EXPOSURE | BISPHENOL-A EXPOSURE | ARYL-HYDROCARBON RECEPTOR | ENDOCRINOLOGY & METABOLISM | Brain - drug effects | Puberty - drug effects | Reproduction - drug effects | Animals | Endocrine Disruptors - pharmacology | Benzhydryl Compounds | Humans | Environmental Pollutants - pharmacology | Behavior, Animal - drug effects | Phytoestrogens - pharmacology | Phenols - pharmacology | Enzymes | Herbicides | Neurosciences | Bisphenol-A | Evolutionary biology | Food contamination | Estrogen | Evolution | Tributylin | Chemicals | Isoflavones | Puberty | Index Medicus | Endocrine disruptors | Catalysts | Circuits | Occupational exposure | Neurotransmitter receptors | Signal transduction | Metabolites | Physiology | Lipid metabolism | Aryl hydrocarbon receptors | House dust | Pesticides | Cholesterol | Reviews | Contaminants | Critical period | Steroid hormones | Pharmaceuticals | Steroids | Brain | Environmental Pollutants | Endocrine Disruptors | Behavior, Animal | Life Sciences | Human health and pathology | Reproduction | Phenols | Endocrinology and metabolism | ethynilestradiol | diphenyl-dichloro-trichloroethane
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6. Full Text A robust analytical method for measurement of phytoestrogens and related metabolites in serum with liquid chromatography tandem mass spectrometry
by Jiang, Hongmei and Liao, Xiangjun and Wood, Carla M and Xiao, Chao-Wu and Feng, Yong-Lai
Journal of Chromatography B, ISSN 1570-0232, 02/2016, Volume 1012-1013, pp. 106 - 112
A sensitive and robust method using high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) was developed for quantitation of 13... 
Core–shell C18 column | Rat serum | Rapid separation | High performance liquid chromatography–tandem mass spectrometry | Phytoestrogens and metabolites | Core-shell C18 column | High performance liquid chromatography-tandem mass spectrometry | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | ISOFLAVONE METABOLITES | MS METHOD | IDENTIFICATION | QUANTITATIVE-ANALYSIS | BREAST-CANCER RISK | ELECTRODE ARRAY DETECTION | DAIDZEIN | HUMAN URINE | SOY | DIETARY PHYTOESTROGENS | Limit of Detection | Phytoestrogens - isolation & purification | Animals | Chromatography, High Pressure Liquid - methods | Phytoestrogens - chemistry | Rats | Female | Rats, Sprague-Dawley | Tandem Mass Spectrometry - methods | Phytoestrogens - blood | Measurement | Metabolites | Analysis | Estrogen | Liquid chromatography | Mass spectrometry | Methods | Biological monitoring | Isoflavones | Casein | High performance liquid chromatography | Diets | Analytical chemistry | Phytoestrogens | Serums | Chromatography
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7. Full Text Phytoestrogens and Breast Cancer Prevention: Possible Mechanisms of Action
by Sarah M. Mense and Tom K. Hei and Ramesh K. Ganju and Hari K. Bhat
Environmental Health Perspectives, ISSN 0091-6765, 4/2008, Volume 116, Issue 4, pp. 426 - 433
Objective: Phytoestrogens display an array of pharmacologic properties, and in recent years investigation of their potential as anticancer agents has increased... 
Enzymes | Phytoestrogens | Cell growth | Estrogens | Cell lines | Estrogen receptors | Breast cancer | Review | Carcinogenesis | Tumors | Isoflavones | Phytoestrogen | Catechol-O-methyltransferase | Estrogen receptor | Chemoprevention | Cytochrome P450 | Estrogen | Catechol estrogen | catechol estrogen | catechol-O-methyltransferase | SPRAGUE-DAWLEY RATS | estrogen | estrogen receptor | breast cancer | FACTOR-KAPPA-B | cytochrome P450 | PREMENOPAUSAL WOMEN | ESTRADIOL-INDUCED TUMORIGENESIS | phytoestrogen | ESTROGEN-RECEPTOR-BETA | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | chemoprevention | ARYL-HYDROCARBON RECEPTOR | HUMAN CYTOCHROME-P450 1A1 | AKT SIGNALING PATHWAY | SOY ISOFLAVONES | TOXICOLOGY | Receptors, Estrogen - metabolism | Estrogens - biosynthesis | Signal Transduction | Humans | Risk Factors | Aromatase - metabolism | Cytochrome P-450 Enzyme System - metabolism | Anticarcinogenic Agents - classification | Phytoestrogens - adverse effects | Breast Neoplasms - metabolism | Breast Neoplasms - prevention & control | Aromatase - genetics | Animals | Cell Enlargement - drug effects | Diet | Phytoestrogens - classification | Anticarcinogenic Agents - adverse effects | Cell Proliferation - drug effects | Breast Neoplasms - chemically induced | Anticarcinogenic Agents - pharmacology | Phytoestrogens - pharmacology | Women | Care and treatment | Diagnosis | Research | Health aspects | Risk factors | Index Medicus
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8. Developing phytoestrogens for breast cancer prevention
by Liu, Mandy M and Huang, Ying and Wang, Jeffrey
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 2012, Volume 12, Issue 10, pp. 1306 - 1313
Breast cancer is one of the most common types of cancer in women, and is the second leading cause of cancer-related deaths in the United States.... 
Phytoestrogens | Aromatase inhibitor | Enterolactone | Chemoprevention | Genistein | Equol | Glycitein | Breast cancer | Estrogen receptor modulator | Sesamin | Coumestrol | Matairesinol | Resveratrol | Daidzein | Enterodiol | Secoisolariciresinol | MAMMARY-TUMORS | POSTMENOPAUSAL WOMEN | SPRAGUE-DAWLEY RATS | CHEMISTRY, MEDICINAL | INHIBITS GROWTH | RESVERATROL CONTENT | PLASMA ENTEROLACTONE | ESTROGEN-RECEPTOR-BETA | ONCOLOGY | TRANS-RESVERATROL | PHYTO-ESTROGENS | DIETARY PHYTOESTROGENS | Estrogen Receptor Modulators - chemistry | Humans | Phytoestrogens - chemistry | Drug Discovery - trends | Drug Discovery - methods | Clinical Trials as Topic | Phytoestrogens - therapeutic use | Estrogen Receptor Modulators - pharmacology | Phytoestrogens - adverse effects | Breast Neoplasms - prevention & control | Estrogen Receptor Modulators - therapeutic use | Animals | Anticarcinogenic Agents - chemistry | Female | Anticarcinogenic Agents - adverse effects | Molecular Structure | Anticarcinogenic Agents - pharmacology | Estrogen Receptor Modulators - adverse effects | Phytoestrogens - pharmacology | Anticarcinogenic Agents - therapeutic use
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9. Full Text Implications of Phytoestrogen Intake for Breast Cancer
by Duffy, Christine and Perez, Kimberly and Partridge, Ann
CA: A Cancer Journal for Clinicians, ISSN 0007-9235, 09/2007, Volume 57, Issue 5, pp. 260 - 277
Phytoestrogens are a group of plant‐derived substances that are structurally or functionally similar to estradiol. Interest in phytoestrogens has been fueled... 
ESTROGEN-RECEPTOR-BETA | CONTROLLED CROSSOVER TRIAL | SUPPRESSES MAMMARY-CANCER | ONCOLOGY | CELLS IN-VITRO | PHYTO-ESTROGENS | PREMENOPAUSAL JAPANESE WOMEN | POSTMENOPAUSAL WOMEN | CHINESE-WOMEN | MMTV/C-NEU MICE | HOT FLASHES | Hot Flashes - drug therapy | United States - epidemiology | Postmenopause - drug effects | Humans | Antineoplastic Agents - therapeutic use | Phytoestrogens - therapeutic use | Breast Neoplasms - prevention & control | Lignans - administration & dosage | Premenopause - drug effects | Receptors, Estrogen - drug effects | Animals | Diet | Female | Genistein - therapeutic use | Phytoestrogens - classification | Phytoestrogens - metabolism | Phytoestrogens - administration & dosage | Isoflavones - administration & dosage | Phytoestrogens - pharmacology | Breast Neoplasms - epidemiology | Disease Models, Animal | Prevention | Relapse | Diet therapy | Soybean products | Breast cancer | Research | Health aspects | Isoflavones | Cancer | Women | Oncology | Hormones | Estrogen
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10. Full Text Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops
by van Breemen, Richard B and Yuan, Yang and Banuvar, Suzanne and Shulman, Lee P and Qiu, Xi and Alvarenga, René F. Ramos and Chen, Shao‐Nong and Dietz, Birgit M and Bolton, Judy L and Pauli, Guido F and Krause, Elizabeth and Viana, Marlos and Nikolic, Dejan
Molecular Nutrition & Food Research, ISSN 1613-4125, 10/2014, Volume 58, Issue 10, pp. 1962 - 1969
Scope Women seeking alternatives to hormone‐replacement therapy for menopausal symptoms often try botanical dietary supplements containing extracts of hops... 
Hops | Isoxanthohumol | 8‐Prenylnaringenin | Xanthohumol | Pharmacokinetics | 8-Prenylnaringenin | TRIFOLIUM-PRATENSE | PRENYLFLAVONOIDS | HUMULUS-LUPULUS L | FOOD SCIENCE & TECHNOLOGY | FLAVONOIDS | POTENT PHYTOESTROGEN | IN-VITRO | METABOLISM | Prenylation | Plant Extracts - chemistry | Humans | Middle Aged | Half-Life | Glucuronides - blood | Dietary Supplements - analysis | Intestinal Absorption | Phytoestrogens - adverse effects | Beer | Phytoestrogens - economics | Plant Extracts - administration & dosage | Plant Extracts - metabolism | Glucuronides - metabolism | Postmenopause | Female | Dietary Supplements - adverse effects | Phytoestrogens - administration & dosage | Humulus - chemistry | Biomarkers - metabolism | Phenols - economics | Biomarkers - blood | Phenols - metabolism | Industrial Waste - analysis | Industrial Waste - economics | Dietary Supplements - economics | Phenols - adverse effects | Inflorescence - chemistry | Phenols - administration & dosage | Phytoestrogens - metabolism | Aged | Kinetics | Methylation | Food-Processing Industry - economics | Enterohepatic Circulation | Plant Extracts - adverse effects | Women | Yuan (China) | Medical examination | Pituitary hormones | Hormone therapy | Menopause | Dietary supplements | Phenols | Thrombin | Hormones, Sex | Blood
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