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Science, ISSN 0036-8075, 5/2013, Volume 340, Issue 6132, pp. 610 - 614
Serotonin or 5-hydroxytryptamine (5-HT) regulates a wide spectrum of human physiology through the 5-HT receptor family. We report the crystal structures of the... 
Receptors | Sand sheets | Hydrogen bonds | Serotonin receptors | REPORTS | Ligands | Agonists | Indoles | Grants | LSD | Binding sites | LIGANDS | PROTEIN-COUPLED RECEPTOR | PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | MUTATION | CARDIAC VALVULOPATHY | VALVULAR HEART-DISEASE | SCHIZOPHRENIA | DISORDERS | FENFLURAMINE | AGONIST | Pindolol - chemistry | Humans | Lysergic Acid Diethylamide - metabolism | Molecular Sequence Data | Crystallography, X-Ray | Propranolol - metabolism | Serotonin 5-HT1 Receptor Agonists - chemistry | Ergotamine - chemistry | Ergotamine - metabolism | Receptor, Serotonin, 5-HT1B - genetics | Receptor, Serotonin, 5-HT1B - metabolism | Binding Sites | Amino Acid Sequence | Tryptamines - chemistry | Norfenfluramine - metabolism | Dihydroergotamine - chemistry | Protein Structure, Secondary | Models, Molecular | Dihydroergotamine - metabolism | Lysergic Acid Diethylamide - chemistry | Propranolol - chemistry | Serotonin 5-HT1 Receptor Agonists - metabolism | Pindolol - analogs & derivatives | Protein Folding | Norfenfluramine - chemistry | Hydrogen Bonding | Mutagenesis | Tryptamines - metabolism | Receptor, Serotonin, 5-HT1B - chemistry | Hydrophobic and Hydrophilic Interactions | Protein Conformation | Molecular Docking Simulation | Pindolol - metabolism | Physiological aspects | Research | G proteins | Serotonin | Molecular biology | Ligands (Biochemistry) | Neurons | Index Medicus
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2011, Volume 54, Issue 19, pp. 6874 - 6887
The growing practice of exploiting noninvasive fluorescence-based techniques to study G protein-coupled receptor pharmacology at the single cell and single... 
NERVOUS-SYSTEM | CHEMISTRY, MEDICINAL | PROTEIN-COUPLED RECEPTOR | AGONIST ACTIONS | DRUG DISCOVERY | PROVIDE EVIDENCE | SINGLE LIVING CELLS | ADRENERGIC-RECEPTORS | NON-SPECIFIC BINDING | BETA-ADRENERGIC RECEPTOR | CORRELATION SPECTROSCOPY | Fluorescent Dyes - chemical synthesis | Pindolol - chemistry | Cricetulus | Stereoisomerism | Humans | Structure-Activity Relationship | Alprenolol - analogs & derivatives | Adrenergic beta-Agonists - chemistry | Adrenergic beta-Antagonists - pharmacology | Alprenolol - chemistry | Propranolol - pharmacology | Pindolol - pharmacology | Boron Compounds - chemical synthesis | Pindolol - chemical synthesis | Fluorescent Dyes - pharmacology | Adrenergic beta-Agonists - chemical synthesis | Propranolol - chemical synthesis | Radioligand Assay | Propranolol - analogs & derivatives | Single-Cell Analysis | Adrenergic beta-Antagonists - chemical synthesis | Alprenolol - pharmacology | Genes, Reporter | CHO Cells | Boron Compounds - chemistry | Boron Compounds - pharmacology | Fluorescent Dyes - chemistry | Cricetinae | Drug Partial Agonism | Adrenergic beta-Agonists - pharmacology | Receptors, Adrenergic, beta-1 - metabolism | Propranolol - chemistry | Receptors, Adrenergic, beta-3 - metabolism | Pindolol - analogs & derivatives | Receptors, Adrenergic, beta-2 - metabolism | Microscopy, Confocal | Animals | Adrenergic beta-Antagonists - chemistry | Ligands | Alprenolol - chemical synthesis
Journal Article
Journal Article
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 1998, Volume 800, Issue 2, pp. 161 - 169
Journal Article