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JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, ISSN 1567-567X, 08/2018, Volume 45, Issue 4, pp. 537 - 555
Journal Article
Journal Article
The Journal of Physiology, ISSN 0022-3751, 05/2004, Volume 556, Issue 3, pp. 739 - 754
Previous studies have outlined an important role for serotonin (5-HT) in the development of synaptic connectivity and function in the cerebral cortex. In this... 
MONOAMINE-OXIDASE | ACTIVATION | PHYSIOLOGY | V PYRAMIDAL CELLS | 5-HT2A RECEPTOR | NEURONS | MEDIODORSAL NUCLEUS | RECEPTORS MEDIATE | CONNECTIONS | LAYER 5 | NEUROSCIENCES | CEREBRAL-CORTEX | Receptors, Serotonin - physiology | Lidocaine - pharmacology | Serotonin - physiology | Amphetamines - pharmacology | Male | Serotonin - pharmacology | Serotonin 5-HT4 Receptor Antagonists | Fluorobenzenes - pharmacology | Serotonin 5-HT2 Receptor Antagonists | Pindolol - pharmacology | Prefrontal Cortex - drug effects | Piperidines - pharmacology | Time Factors | Pyramidal Cells - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Pyramidal Cells - drug effects | Tetrodotoxin - pharmacology | Phenols - pharmacology | Synapses - drug effects | GABA-A Receptor Antagonists | Glutamic Acid - pharmacology | Receptors, AMPA - physiology | Synapses - physiology | Rats | Sodium Channel Blockers - pharmacology | Bicuculline - pharmacology | Pindolol - analogs & derivatives | Prefrontal Cortex - cytology | Serotonin Antagonists - pharmacology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Lidocaine - analogs & derivatives | Patch-Clamp Techniques | Receptor, Serotonin, 5-HT2A - physiology | Animals | Receptors, Serotonin, 5-HT4 - physiology | Prefrontal Cortex - physiology | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Serotonin 5-HT1 Receptor Antagonists | Receptors, AMPA - antagonists & inhibitors | Research Papers
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 01/2012, Volume 674, Issue 2-3, pp. 307 - 314
We have recently shown that the ethanol extract of the leaves of exhibits an antidepressant-like effect in the tail suspension and forced swimming tests in... 
Forced swimming test | Hypnotic | Podoandin | Sesquiterpene lactone | Hedyosmum brasiliense | Antidepressant effect | DEPRESSION | TAIL SUSPENSION TEST | ELECTROCONVULSIVE-THERAPY | GUANOSINE-MONOPHOSPHATE PATHWAY | REUPTAKE INHIBITORS | 5-HT3 RECEPTOR | L-ARGININE | NITRIC-OXIDE | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | Cycloheptanes - pharmacology | Sesquiterpenes - isolation & purification | Plant Extracts - pharmacology | 4-Butyrolactone - isolation & purification | Male | Antidepressive Agents - isolation & purification | Lactones - pharmacology | Drug Interactions | Antidepressive Agents - pharmacology | Swimming | Dopamine - metabolism | Locomotion - drug effects | Fluoxetine - pharmacology | Lactones - isolation & purification | 4-Butyrolactone - pharmacology | Neurotransmitter Agents - metabolism | Plant Extracts - isolation & purification | Animals | Norepinephrine - metabolism | Cyclic GMP - metabolism | Serotonin - metabolism | Mice | 4-Butyrolactone - analogs & derivatives | Analgesics, Opioid - metabolism | Sesquiterpenes - pharmacology | Nitric Oxide - metabolism | Arginine - metabolism | Cycloheptanes - isolation & purification | Epinephrine - metabolism | Ferns - chemistry | Serotonin | Antidepressants | Analysis | Medicine, Botanic | GABA | Medicine, Herbal | Haloperidol | gamma -Aminobutyric acid | p-Chlorophenylalanine | Dopamine | Ethanol | yohimbine | sesquiterpenoids | Leaves | Naloxone | Arginine | pindolol | Opioids | Naltrindole | Norepinephrine | Bicuculline | prazosin | sulpiride
Journal Article
Hypertension, ISSN 0194-911X, 01/1999, Volume 33, Issue 1S Suppl, pp. 467 - 471
The mechanisms for the vascular actions of vasodilatory beta-blockers remain undetermined. For some kinds of beta-blockers, the involvement of nitric oxide... 
Receptors, adrenergic, beta | 5-hydroxytryptamine | Nitric oxide | Kidney | nitric oxide | STIMULATION | TERTATOLOL | HEART-FAILURE | DILATION | CONSCIOUS DOGS | kidney | CANINE CORONARY-ARTERIES | RELAXATIONS | PERIPHERAL VASCULAR DISEASE | receptors, adrenergic, beta | RECEPTORS | HYPERTENSION | DILATATION | Kidney - physiology | Ethanolamines - pharmacology | Celiprolol - pharmacology | Rats, Wistar | Renal Circulation - physiology | Endothelium, Vascular - drug effects | Hypertension - drug therapy | Male | Endothelium, Vascular - physiology | Dose-Response Relationship, Drug | Adrenergic beta-Antagonists - pharmacology | Phenylephrine - pharmacology | Pindolol - pharmacology | Piperidines - pharmacology | Aorta, Thoracic - physiology | Hypertension - chemically induced | Platelet Aggregation Inhibitors - pharmacology | Renal Circulation - drug effects | Aorta, Thoracic - drug effects | Benzopyrans - pharmacology | Kidney - physiopathology | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | NG-Nitroarginine Methyl Ester - pharmacology | Nebivolol | Kidney - drug effects | Vasodilator Agents - pharmacology | Desoxycorticosterone | Metergoline - pharmacology | Nitric Oxide Synthase Type III | Rats | Pindolol - analogs & derivatives | Serotonin Antagonists - pharmacology | Piperazines - pharmacology | Vasoconstriction - drug effects | Hypertension - physiopathology | Animals | Nitric Oxide Synthase - metabolism | In Vitro Techniques | Quinazolines - pharmacology
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2011, Volume 54, Issue 19, pp. 6874 - 6887
The growing practice of exploiting noninvasive fluorescence-based techniques to study G protein-coupled receptor pharmacology at the single cell and single... 
NERVOUS-SYSTEM | CHEMISTRY, MEDICINAL | PROTEIN-COUPLED RECEPTOR | AGONIST ACTIONS | DRUG DISCOVERY | PROVIDE EVIDENCE | SINGLE LIVING CELLS | ADRENERGIC-RECEPTORS | NON-SPECIFIC BINDING | BETA-ADRENERGIC RECEPTOR | CORRELATION SPECTROSCOPY | Fluorescent Dyes - chemical synthesis | Pindolol - chemistry | Cricetulus | Stereoisomerism | Humans | Structure-Activity Relationship | Alprenolol - analogs & derivatives | Adrenergic beta-Agonists - chemistry | Adrenergic beta-Antagonists - pharmacology | Alprenolol - chemistry | Propranolol - pharmacology | Pindolol - pharmacology | Boron Compounds - chemical synthesis | Pindolol - chemical synthesis | Fluorescent Dyes - pharmacology | Adrenergic beta-Agonists - chemical synthesis | Propranolol - chemical synthesis | Radioligand Assay | Propranolol - analogs & derivatives | Single-Cell Analysis | Adrenergic beta-Antagonists - chemical synthesis | Alprenolol - pharmacology | Genes, Reporter | CHO Cells | Boron Compounds - chemistry | Boron Compounds - pharmacology | Fluorescent Dyes - chemistry | Cricetinae | Drug Partial Agonism | Adrenergic beta-Agonists - pharmacology | Receptors, Adrenergic, beta-1 - metabolism | Propranolol - chemistry | Receptors, Adrenergic, beta-3 - metabolism | Pindolol - analogs & derivatives | Receptors, Adrenergic, beta-2 - metabolism | Microscopy, Confocal | Animals | Adrenergic beta-Antagonists - chemistry | Ligands | Alprenolol - chemical synthesis
Journal Article
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2000, Volume 398, Issue 2, pp. 285 - 296
Journal Article
Journal Article
Journal of Clinical Psychiatry, ISSN 0160-6689, 2001, Volume 62, Issue 15, pp. 12 - 17
Although selective serotonin reuptake inhibitors (SSRIs) block serotonin (5-HT) reuptake rapidly, their therapeutic action is delayed. The increase in synaptic... 
ELECTROCONVULSIVE-THERAPY | PSYCHIATRY | DOUBLE-BLIND | PAROXETINE | PLACEBO-CONTROLLED TRIAL | MAJOR DEPRESSION | 5-HT NEUROTRANSMISSION | RAT-BRAIN | PINDOLOL | PSYCHOLOGY, CLINICAL | FLUOXETINE | ANTAGONIST MIRTAZAPINE | Pyramidal Cells - metabolism | Serotonin - physiology | Synaptic Transmission - physiology | Norepinephrine - physiology | Autoreceptors - metabolism | Humans | Mianserin - therapeutic use | Receptors, Serotonin - drug effects | Depressive Disorder - drug therapy | Hippocampus - drug effects | Receptor, Serotonin, 5-HT1B | Mianserin - analogs & derivatives | Mianserin - pharmacology | Pindolol - pharmacology | Receptors, Adrenergic, alpha - drug effects | Receptors, Adrenergic - drug effects | Pindolol - therapeutic use | Synaptic Transmission - drug effects | Pyramidal Cells - drug effects | Cyclohexanols - pharmacology | Drug Therapy, Combination | Receptors, Adrenergic, alpha - metabolism | Receptors, Adrenergic - metabolism | Serotonin Uptake Inhibitors - therapeutic use | Treatment Outcome | Hippocampus - cytology | Depressive Disorder - metabolism | Receptors, Serotonin - metabolism | Autoreceptors - drug effects | Drug Synergism | Venlafaxine Hydrochloride | Hippocampus - metabolism | Norepinephrine - metabolism | Raphe Nuclei - drug effects | Raphe Nuclei - physiology | Antidepressive Agents, Tricyclic - therapeutic use | Receptors, Serotonin, 5-HT1 | Antidepressive Agents, Tricyclic - pharmacology | Serotonin - metabolism | Serotonin Uptake Inhibitors - pharmacology
Journal Article
Journal Article