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Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7323, pp. 557 - 561
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 11/2012, Volume 30, Issue 32, pp. 4017 - 4025
Therapeutic drug monitoring (TDM) provides valuable guidance for dose adjustment of antibiotics, immunosuppressives, antiepileptics, and other drugs, but its... 
ANTI-CD20 MONOCLONAL-ANTIBODY | ONCOLOGY | FC-GAMMA-RIIIA | PROGRESSION-FREE SURVIVAL | MULTICENTER PHASE-II | SQUAMOUS-CELL CARCINOMA | TYROSINE KINASE INHIBITOR | ENDOTHELIAL GROWTH-FACTOR | SUNITINIB MALATE SU11248 | CHRONIC MYELOID-LEUKEMIA | IMATINIB PLASMA-LEVELS | Neoplasms - metabolism | Niacinamide - analogs & derivatives | Piperazines - administration & dosage | Thiazoles - blood | Injections, Intravenous | Area Under Curve | Pyrimidines - blood | Humans | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Half-Life | Thiazoles - administration & dosage | Phenylurea Compounds | Antineoplastic Agents - administration & dosage | Benzenesulfonates - administration & dosage | Drug Monitoring - methods | Indoles - administration & dosage | Antibodies, Monoclonal - blood | Antibodies, Monoclonal, Humanized | Neoplasms - blood | Antineoplastic Agents - adverse effects | Pyrroles - administration & dosage | Benzenesulfonates - blood | Antineoplastic Agents - pharmacokinetics | Cetuximab | Piperazines - blood | Everolimus | Molecular Targeted Therapy - methods | Dasatinib | Sirolimus - analogs & derivatives | Pyridines - administration & dosage | Pyrimidines - administration & dosage | Indoles - blood | Rituximab | Pyrroles - blood | Sirolimus - blood | Evidence-Based Medicine | Imatinib Mesylate | Neoplasms - drug therapy | Sirolimus - administration & dosage | Antibodies, Monoclonal, Murine-Derived - blood | Pyridines - blood | Animals | Antibodies, Monoclonal - administration & dosage | Antineoplastic Agents - blood | Benzamides
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2017, Volume 37, Issue 8, pp. 1503 - 1512
OBJECTIVE—Phosphatidylserine exposure mediates platelet procoagulant function and regulates platelet life span. Apoptotic, necrotic, and integrin-mediated... 
phosphatidylserine | blood platelet | cell death | cytosol | mitochondrial membrane | PERMEABILITY TRANSITION PORE | ACTIVATION | BLOOD-COAGULATION | INTEGRIN ALPHA(IIB)BETA | PROCOAGULANT PLATELETS | CELL-DEATH | THROMBUS GROWTH | CALCIUM | SURFACE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPOSURE | Crotalid Venoms - pharmacology | Apoptosis - drug effects | Venous Thrombosis - blood | bcl-2 Homologous Antagonist-Killer Protein - genetics | Mitochondria - ultrastructure | Necrosis | Mitochondrial Membranes - drug effects | Cytochromes c - blood | Thrombin - pharmacology | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | bcl-2 Homologous Antagonist-Killer Protein - blood | Platelet Aggregation - drug effects | Blood Platelets - drug effects | Integrins - blood | bcl-2-Associated X Protein - blood | bcl-2-Associated X Protein - genetics | Disease Models, Animal | Cyclophilins - blood | Signal Transduction | Lectins, C-Type | Genotype | Cyclophilins - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Sulfonamides - pharmacology | Piperazines - pharmacology | Mice, Knockout | Mitochondrial Membranes - metabolism | Phenotype | Animals | Blood Coagulation - drug effects | Blood Platelets - metabolism | Blood Platelets - ultrastructure | Venous Thrombosis - genetics | Caspases - blood | Kinetics | Venous Thrombosis - pathology | Phosphatidylserines - blood | platelet | inner mitochondrial membrane
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 09/2007, Volume 102, Issue 6, pp. 1749 - 1757
Imatinib, a protein tyrosine kinase inhibitor, may prevent the growth of glioblastoma cells. Unfortunately, its brain distribution is restricted by... 
CGP74588 | mouse | p‐glycoprotein | imatinib | blood–brain barrier | breast cancer resistance protein | Imatinib | Blood-brain barrier | Mouse | Breast cancer resistance protein | p-glycoproteinz | blood-brain barrier | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | p-glycoprotein | C-KIT | DRUG-RESISTANCE | DEFICIENT MICE | GF120918 | NEUROSCIENCES | REVERSAL | IN-VITRO | PHARMACOKINETICS | TYROSINE KINASE INHIBITOR | MULTIDRUG-RESISTANCE | Male | Piperazines - metabolism | Cyclosporins - pharmacology | Pyrimidines - metabolism | Quinolines - pharmacology | Antineoplastic Agents - metabolism | Brain - metabolism | Dose-Response Relationship, Drug | Brain - blood supply | ATP Binding Cassette Transporter, Subfamily B, Member 1 | ATP-Binding Cassette Transporters - genetics | Biological Transport, Active - physiology | ATP-Binding Cassette Transporters - metabolism | Dibenzocycloheptenes - pharmacology | ATP Binding Cassette Transporter, Subfamily B - genetics | Piperazines - pharmacokinetics | Immunosuppressive Agents - pharmacology | ATP Binding Cassette Transporter, Subfamily G, Member 2 | Tetrahydroisoquinolines - pharmacology | Biological Transport, Active - drug effects | Enzyme Inhibitors - pharmacology | Blood-Brain Barrier - drug effects | Imatinib Mesylate | ATP Binding Cassette Transporter, Subfamily B - metabolism | Blood-Brain Barrier - metabolism | Mice, Knockout | Brain - drug effects | Animals | ATP Binding Cassette Transporter, Subfamily B - antagonists & inhibitors | Acridines - pharmacology | Pyrimidines - pharmacokinetics | Mice | Benzamides | ATP-Binding Cassette Transporters - antagonists & inhibitors | Physiological aspects | Breast cancer | Proteins | Neurosciences | Inhibitor drugs | Rodents | Biochemistry | Glycoproteins
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2008, Volume 14, Issue 7, pp. 731 - 737
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 10/2012, Volume 10, Issue 10, pp. 1999 - 2005
Background:  Post‐treatment platelet reactivity (PR) is associated with ischemic and bleeding events in patients receiving P2Y12 receptor antagonists.... 
Vasodilator‐Stimulated Phosphoprotein index | bleedings | platelet monitoring | stent thrombosis | P2Y12‐ADP receptor antagonist | P2Y12-ADP receptor antagonist | Stent thrombosis | Vasodilator-Stimulated Phosphoprotein index | Platelet monitoring | Bleedings | THERAPEUTIC WINDOW | DEFINITION | MYOCARDIAL-INFARCTION | CARDIOVASCULAR EVENTS | STENT PLACEMENT | TRIAL | PERCUTANEOUS CORONARY INTERVENTION | CLOPIDOGREL | BLOOD-TRANSFUSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ACTIVE METABOLITE | Prasugrel Hydrochloride | Predictive Value of Tests | Thiophenes - therapeutic use | Prospective Studies | Follow-Up Studies | Percutaneous Coronary Intervention - mortality | Humans | Middle Aged | Receptors, Purinergic P2Y12 - drug effects | Male | Purinergic P2Y Receptor Antagonists - adverse effects | Phosphoproteins - blood | Receptors, Purinergic P2Y12 - blood | Time Factors | Coronary Thrombosis - prevention & control | Odds Ratio | Coronary Thrombosis - blood | Platelet Aggregation Inhibitors - adverse effects | Risk Assessment | Risk Factors | Myocardial Ischemia - prevention & control | Piperazines - therapeutic use | Piperazines - adverse effects | Blood Platelets - metabolism | Acute Coronary Syndrome - therapy | Coronary Thrombosis - etiology | Hemorrhage - chemically induced | Percutaneous Coronary Intervention - adverse effects | Multivariate Analysis | Thiophenes - adverse effects | Acute Coronary Syndrome - mortality | Microfilament Proteins - blood | Platelet Function Tests | Female | Myocardial Ischemia - mortality | Platelet Aggregation - drug effects | Blood Platelets - drug effects | France | Platelet Aggregation Inhibitors - therapeutic use | Purinergic P2Y Receptor Antagonists - therapeutic use | Cell Adhesion Molecules - blood | Coronary Thrombosis - mortality | Kaplan-Meier Estimate | Myocardial Ischemia - blood | Proportional Hazards Models | Linear Models | Treatment Outcome | Acute Coronary Syndrome - blood | Myocardial Ischemia - etiology | Transluminal angioplasty | Coronary heart disease | Vasodilators | Analysis | Cardiac patients
Journal Article
Human brain mapping, ISSN 1065-9471, 02/2013, Volume 34, Issue 2, pp. 272 - 282
Journal Article
Annals of Neurology, ISSN 0364-5134, 12/2011, Volume 70, Issue 6, pp. 920 - 931
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2009, Volume 45, Issue 11, pp. 1959 - 1968
Journal Article
Journal Article