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ENDOCRINE PRACTICE, ISSN 1530-891X, 11/2011, Volume 17, Issue 6, pp. 941 - 948
Journal Article
Journal Article
Journal of Pediatric Endocrinology and Metabolism, ISSN 0334-018X, 02/2012, Volume 25, Issue 1, pp. 221 - 223
Decreased bone mineral density (BMD) has been documented in adults with Cushing disease (CD), and allelic variants of the vitamin D receptor (VDR) gene have... 
genetics | glucocorticoids | osteoporosis | Cushing syndrome | pediatrics | Osteoporosis | Pediatrics | Genetics | Glucocorticoids | ENDOCRINOLOGY & METABOLISM | SURGICAL CURE | Pituitary ACTH Hypersecretion - genetics | Bone Density | Pituitary ACTH Hypersecretion - metabolism | Humans | Adolescent | Female | Male | Child | Receptors, Calcitriol - genetics | Polymorphism, Genetic
Journal Article
Domestic Animal Endocrinology, ISSN 0739-7240, 01/2009, Volume 36, Issue 1, pp. 3 - 12
Cushing's disease caused by pituitary corticotroph adenoma is a common endocrine disease in dogs. A characteristic biochemical feature of corticotroph adenomas... 
Negative feedback | Dog | Corticotroph adenoma | Pituitary | Cushing's disease | AGRICULTURE, DAIRY & ANIMAL SCIENCE | RIBONUCLEIC-ACID LEVELS | MINERALOCORTICOID-RECEPTOR | TRANSSPHENOIDAL HYPOPHYSECTOMY | PITUITARY-DEPENDENT HYPERADRENOCORTICISM | MESSENGER-RNA LEVELS | 11-BETA-HYDROXYSTEROID DEHYDROGENASE | AGE-RELATED-CHANGES | RAT ANTERIOR-PITUITARY | ENDOCRINOLOGY & METABOLISM | MOLECULAR PATHOGENESIS | RECEPTOR-BINDING | Receptors, Mineralocorticoid - genetics | Gene Expression - genetics | 11-beta-Hydroxysteroid Dehydrogenases - genetics | RNA, Messenger - analysis | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Adrenocorticotropic Hormone - genetics | Pituitary ACTH Hypersecretion - genetics | ACTH-Secreting Pituitary Adenoma - genetics | Glucocorticoids - physiology | Female | Pro-Opiomelanocortin - genetics | ACTH-Secreting Pituitary Adenoma - veterinary | Pituitary Neoplasms - genetics | Dog Diseases - genetics | Adrenocorticotropic Hormone - biosynthesis | Reverse Transcriptase Polymerase Chain Reaction | ACTH-Secreting Pituitary Adenoma - chemistry | Feedback, Physiological | Animals | Dogs | Receptors, Glucocorticoid - genetics | Pituitary Neoplasms - chemistry | Pituitary ACTH Hypersecretion - veterinary | Pituitary Neoplasms - veterinary | Corticosteroids | RNA | Genes | Neurohormones | Genetic research | ACTH | Intermedin | Gene expression | Steroids
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2011, Volume 121, Issue 12, pp. 4712 - 4721
Cushing disease is a condition in which the pituitary gland releases excessive adrenocorticotropic hormone (ACTH) as a result of an adenoma arising from the... 
NUCLEAR-LOCALIZATION | MEDICINE, RESEARCH & EXPERIMENTAL | DEPENDENT CUSHINGS-SYNDROME | GEFITINIB INDUCES APOPTOSIS | CYCLE INHIBITOR P27(KIP1) | EPIDERMAL-GROWTH-FACTOR | CORTICOTROPH TUMORS | T-BOX FACTOR | FACTOR RECEPTOR | PROGNOSTIC VALUE | MICE LACKING | ACTH-Secreting Pituitary Adenoma - drug therapy | Neoplasm Transplantation | Humans | Cell Line, Tumor - drug effects | Molecular Targeted Therapy | Pituitary ACTH Hypersecretion - drug therapy | ACTH-Secreting Pituitary Adenoma - complications | Adenoma - enzymology | Adenoma - complications | Dog Diseases - drug therapy | Dog Diseases - etiology | Secretory Rate - drug effects | Adenoma - drug therapy | Corticosterone - blood | Gene Expression Regulation, Neoplastic - drug effects | Pro-Opiomelanocortin - genetics | Adenoma - veterinary | Promoter Regions, Genetic | Pituitary ACTH Hypersecretion - etiology | ACTH-Secreting Pituitary Adenoma - veterinary | Cell Line, Tumor - enzymology | Tumor Burden | Adrenocorticotropic Hormone - secretion | Pituitary ACTH Hypersecretion - blood | Adenoma - blood | Dog Diseases - blood | ACTH-Secreting Pituitary Adenoma - blood | Animals | Mice, Nude | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Dogs | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Protein Kinase Inhibitors - pharmacology | ACTH-Secreting Pituitary Adenoma - enzymology | Pituitary ACTH Hypersecretion - veterinary | Quinazolines - pharmacology | Drug Screening Assays, Antitumor | Care and treatment | Pituitary gland tumors | ACTH | Drug targeting | Adenoma | Diagnosis | Research | Properties
Journal Article
Journal Article
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 12/2013, Volume 98, Issue 12, pp. E1880 - E1890
Context: Corticotroph pituitary adenomas often highly express the dopamine 2 receptor (D2R) and somatostatin receptor subtype 5 (sst5). The sst2 expression is... 
POTENT INHIBITOR | OCTREOTIDE | ACTH-SECRETION | INTERNALIZATION | GLUCOCORTICOIDS | CORTICOTROPH ADENOMAS | ENDOCRINOLOGY & METABOLISM | ADRENOCORTICOTROPIN SECRETION | NELSONS SYNDROME | TUMOR-CELLS | PITUITARY-ADENOMAS | ACTH-Secreting Pituitary Adenoma - drug therapy | Pituitary Gland - metabolism | Humans | Middle Aged | Hydrocortisone - secretion | Hydrocortisone - urine | Male | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Receptors, Dopamine D2 - metabolism | ACTH-Secreting Pituitary Adenoma - physiopathology | Somatostatin - pharmacology | Receptors, Somatostatin - genetics | Young Adult | Receptors, Somatostatin - agonists | Protein Isoforms - metabolism | Adult | Female | Receptors, Somatostatin - antagonists & inhibitors | Adrenal Glands - secretion | Antineoplastic Agents - pharmacology | Receptors, Somatostatin - metabolism | Tumor Cells, Cultured | Adrenal Glands - drug effects | Neoplasm Proteins - genetics | Pituitary ACTH Hypersecretion - prevention & control | Dopamine Agonists - pharmacology | Somatostatin - analogs & derivatives | Pituitary ACTH Hypersecretion - etiology | ACTH-Secreting Pituitary Adenoma - metabolism | Pituitary Gland - pathology | Receptors, Dopamine D2 - genetics | Gene Expression Regulation - drug effects | Neoplasm Proteins - agonists | Adolescent | Aged | Dopamine D2 Receptor Antagonists | ACTH-Secreting Pituitary Adenoma - pathology | Pituitary Gland - drug effects | Protein Isoforms - genetics
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2002, Volume 99, Issue 5, pp. 3087 - 3092
Journal Article