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Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 45, pp. 32720 - 32730
Background: The expression of PAC1, a specific receptor for PACAP, is decreased in brain ischemia. Results:PAC1 expression was attenuated by inactivation of... 
APOPTOSIS | Gene Expression | Neurons | Pituitary Adenylate Cyclase-activating Polypeptide | ER-STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSIENT FOCAL ISCHEMIA | INDUCTION | Neuropeptide | Transglutaminase 2 | NERVE GROWTH-FACTOR | ER Stress | Ischemia | Sp1 | PAC1 | ENDOPLASMIC-RETICULUM | G Protein-coupled Receptors (GPCRs) | PC12 CELLS | TISSUE TRANSGLUTAMINASE | EXPRESSION | GTP-Binding Proteins - antagonists & inhibitors | Transglutaminases - genetics | Sp1 Transcription Factor - metabolism | Thiourea - pharmacology | GTP-Binding Proteins - genetics | MAP Kinase Signaling System | Enzyme Induction - drug effects | Cystamine - pharmacology | Transglutaminases - antagonists & inhibitors | Cell Hypoxia - drug effects | Response Elements | Enzyme Inhibitors - pharmacology | Transglutaminases - biosynthesis | Enzyme Activation - drug effects | Cinnamates - pharmacology | Enzyme Induction - genetics | Animals | Sp1 Transcription Factor - genetics | Tunicamycin - pharmacology | Endoplasmic Reticulum Stress | Cell Line, Tumor | Enzyme Repression - genetics | Anti-Bacterial Agents - pharmacology | GTP-Binding Proteins - biosynthesis | Mice | Enzyme Repression - drug effects | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Cell Hypoxia - genetics | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - biosynthesis | Thiourea - analogs & derivatives | Neurobiology
Journal Article
Neurotoxicology, ISSN 0161-813X, 09/2017, Volume 62, pp. 30 - 38
Journal Article
Journal Article
Regulatory Peptides, ISSN 0167-0115, 12/2004, Volume 123, Issue 1-3, pp. 107 - 116
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2000, Volume 277, Issue 1, pp. 270 - 279
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2013, Volume 33, Issue 9, pp. 3865 - 3878
During corticogenesis, pituitary adenylate cyclase-activating polypeptide (PACAP; ADCYAP1) may contribute to proliferation control by activating PAC1 receptors... 
SIGNAL-TRANSDUCTION | PROGENITOR CELLS | NEURAL STEM-CELLS | CORTICAL NEUROGENESIS | RETINOIC ACID | VASOACTIVE-INTESTINAL-PEPTIDE | NUMB ISOFORMS | GENE-EXPRESSION | FIBROBLAST-GROWTH-FACTOR | SPLICE VARIANTS | NEUROSCIENCES | RNA, Small Interfering - genetics | Mitogens - pharmacology | Calcium - metabolism | Embryo, Mammalian | Humans | Cell Survival - genetics | Male | Neurogenesis - genetics | Protein Kinase C - metabolism | Estrenes - pharmacology | RNA Isoforms - metabolism | Neurons - metabolism | Gene Expression Regulation, Developmental - physiology | Tretinoin - pharmacology | Cell Survival - drug effects | RNA Isoforms - genetics | Enzyme Inhibitors - pharmacology | Gene Expression Regulation, Developmental - drug effects | Rats | Rats, Sprague-Dawley | Cell Division - drug effects | Mice, Knockout | Mitogens - deficiency | Mice | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Cell Cycle - drug effects | Cerebral Ventricles - cytology | RNA, Small Interfering - metabolism | Cell Cycle - genetics | Age Factors | Gene Expression Regulation, Developmental - genetics | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Flow Cytometry | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Pyrrolidinones - pharmacology | Female | Neurogenesis - drug effects | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Bromodeoxyuridine - metabolism | Cerebral Ventricles - embryology | Neurons - drug effects | Cell Division - genetics | In Situ Nick-End Labeling | Pituitary Adenylate Cyclase-Activating Polypeptide - genetics | Mice, Inbred C57BL | Cells, Cultured | Nerve Tissue Proteins - metabolism | Pregnancy | Animals | MAP Kinase Signaling System - drug effects | Cerebral Cortex - embryology | Mitogens - genetics | Cell Proliferation - drug effects | Pyridines - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - deficiency
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 11/2005, Volume 19, Issue 11, pp. 2798 - 2811
Pituitary adenylate cyclase-activating polypeptide (PACAP) acts as a feed-forward, paracrine/autocrine factor in the hypothalamic ventromedial nucleus (VMN)... 
MESSENGER-RNA | NEURITE OUTGROWTH | ANTERIOR-PITUITARY | PROTEIN-KINASE | ENDOCRINOLOGY & METABOLISM | INTESTINAL POLYPEPTIDE | SEXUAL-BEHAVIOR | CENTRAL-NERVOUS-SYSTEM | REPRODUCTIVE-BEHAVIOR | HYPOTHALAMIC NEURONS | EXPRESSION | Ventromedial Hypothalamic Nucleus - drug effects | Receptors, Vasoactive Intestinal Polypeptide, Type I - antagonists & inhibitors | Dopamine and cAMP-Regulated Phosphoprotein 32 - genetics | RNA, Messenger - analysis | RNA, Messenger - metabolism | Estradiol | Receptors, Vasoactive Intestinal Peptide, Type II - genetics | Posture | Vasoactive Intestinal Peptide - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Cyclic AMP-Dependent Protein Kinase Type II | Female | Steroids - pharmacology | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - metabolism | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Progesterone - pharmacology | Sexual Behavior, Animal - drug effects | Arcuate Nucleus of Hypothalamus - chemistry | Cyclic AMP-Dependent Protein Kinases - metabolism | Receptors, Vasoactive Intestinal Peptide, Type II - antagonists & inhibitors | Arcuate Nucleus of Hypothalamus - metabolism | DNA, Antisense - pharmacology | Receptors, Vasoactive Intestinal Peptide, Type II - metabolism | Ventromedial Hypothalamic Nucleus - chemistry | Rats | Ventromedial Hypothalamic Nucleus - metabolism | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | Receptors, Vasoactive Intestinal Polypeptide, Type I - genetics | Cyclic AMP - antagonists & inhibitors | Animals | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - antagonists & inhibitors
Journal Article