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Circulation Research, ISSN 0009-7330, 06/2008, Volume 102, Issue 12, pp. 1566 - 1574
A human-specific splicing variant of vascular endothelial growth factor (VEGF) receptor 1 (Flt1) was discovered, producing a soluble receptor (designated... 
Vascular smooth muscle cell | Splicing | Soluble VEGF receptor | Preeclampsia | VEGF | CARDIAC & CARDIOVASCULAR SYSTEMS | PLACENTA | soluble VEGF receptor | preeclampsia | REACTIVE OXYGEN | GENE-EXPRESSION | MALARIA | PERIPHERAL VASCULAR DISEASE | splicing | vascular smooth muscle cell | HYPERTENSION | HEMATOLOGY | Muscle, Smooth, Vascular - metabolism | Humans | Recombinant Fusion Proteins - physiology | Vascular Endothelial Growth Factor Receptor-1 - physiology | Homeostasis | Molecular Sequence Data | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Protein Isoforms - blood | RNA Splicing - physiology | Protein Processing, Post-Translational - drug effects | Protein Isoforms - chemistry | Female | Phosphorylation - drug effects | Myocytes, Smooth Muscle - metabolism | Vascular Endothelial Growth Factor A - pharmacology | Vascular Endothelial Growth Factor Receptor-1 - genetics | Amino Acid Sequence | Trophoblasts - metabolism | Endothelial Cells - metabolism | Cornea - chemistry | Muscle, Smooth, Vascular - cytology | Organ Specificity | Vascular Endothelial Growth Factor Receptor-1 - chemistry | Protein Isoforms - physiology | Placenta - metabolism | Pregnancy | Neovascularization, Physiologic - physiology | Placenta - blood supply | Animals | Pre-Eclampsia - blood | Signal Transduction - physiology | Cells, Cultured - metabolism | Vascular Endothelial Growth Factor Receptor-1 - blood | Sus scrofa | Protein Isoforms - genetics | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 02/2013, Volume 152, Issue 5, pp. 1065 - 1076
Journal Article
Journal Article
Placenta, ISSN 0143-4004, 2014, Volume 36, Issue 3, pp. 270 - 278
Abstract Introduction The epidermal growth factor (EGF) signaling system regulates trophoblast differentiation, and its disruption could contribute to... 
Internal Medicine | Obstetrics and Gynecology | Epidermal growth factors | Preeclampsia | Placenta | CELLS | OXIDATIVE STRESS | CYTOTROPHOBLASTS | EGF | HUMAN-PLACENTA | TROPHOBLAST APOPTOSIS | DEVELOPMENTAL BIOLOGY | FACTOR RECEPTOR | OBSTETRICS & GYNECOLOGY | RETARDATION | REPRODUCTIVE BIOLOGY | EARLY-PREGNANCY | ENDOMETRIAL | Receptor, Epidermal Growth Factor - genetics | Humans | Trophoblasts - pathology | Young Adult | Receptor, Epidermal Growth Factor - metabolism | Protein Isoforms - metabolism | Protein Isoforms - chemistry | Transforming Growth Factor alpha - blood | Epidermal Growth Factor - chemistry | Heparin-binding EGF-like Growth Factor - blood | Peptide Fragments - blood | Adult | Female | Pre-Eclampsia - metabolism | Transforming Growth Factor alpha - metabolism | Peptide Fragments - metabolism | Trophoblasts - metabolism | Placentation | Down-Regulation | Epidermal Growth Factor - metabolism | Chorionic Villi - metabolism | Pre-Eclampsia - pathology | Epidermal Growth Factor - blood | Receptor, Epidermal Growth Factor - chemistry | Heparin-binding EGF-like Growth Factor - metabolism | Placenta - metabolism | Pregnancy | Chorionic Villi - pathology | Pre-Eclampsia - blood | Placenta - pathology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Cell Line, Transformed | Apoptosis | Cohort Studies | Protein Isoforms - genetics | Physiological aspects | Medical colleges | Epidermal growth factor | Cells | Index Medicus | placenta | epidermal growth factors | preeclampsia
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2011, Volume 55, Issue 6, pp. 1339 - 1345
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 4, pp. 1451 - 1455
Preeclampsia is a relatively common pregnancy-related disorder. Both maternal and fetal lives will be endangered if it proceeds unabated. Recently, the... 
Hypertension | Pregnancy | Animal models | Reproduction | Placenta | Fetal growth retardation | Preeclampsia | Blastocyst | Blood pressure | Female animals | Hemolytic anemia, elevated liver enzymes, and low platelet count | Trophoblast | 3-hydroxy-3-methyl-glutaryl-CoA | LOVASTATIN | ANGIOGENESIS | LENTIVIRUS | MULTIDISCIPLINARY SCIENCES | SOLUBLE ENDOGLIN | hemolytic anemia, elevated liver enzymes, and low platelet count | PREGNANCY | GENE-TRANSFER | FETAL | trophoblast | SIMVASTATIN | HYPERTENSION | EXPOSURE | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Pre-Eclampsia - genetics | Humans | Pregnancy Proteins - genetics | Male | Pregnancy Proteins - metabolism | Pre-Eclampsia - prevention & control | HEK293 Cells | Female | Lentivirus - genetics | Pre-Eclampsia - metabolism | Disease Models, Animal | Vascular Endothelial Growth Factor Receptor-1 - genetics | Animals, Newborn | Pravastatin - pharmacology | Cell Line | Transduction, Genetic | Injections, Intraperitoneal | Mice, Transgenic | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Placenta - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Pravastatin - administration & dosage | Placenta Growth Factor | Mice | Development and progression | Models | Dosage and administration | Drug therapy | Pravastatin | Vascular endothelial growth factor | Health aspects | Enzymes | Animal reproduction | Cell growth | Rodents | Kinases | Gene expression | Index Medicus | Biological Sciences
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2019, Volume 143, pp. 300 - 308
Free heme activates erythroblasts to express and secrete Placenta Growth Factor (PlGF), an angiogenic peptide of the VEGF family. High circulating levels of... 
Oxidative stress | NRF2 | Sickle cell disease | Placenta growth factor | Pulmonary hypertension | Index Medicus
Journal Article
Journal Article
Science, ISSN 0036-8075, 01/2014, Volume 343, Issue 6173, pp. 885 - 888
Journal Article
Clinical Epigenetics, ISSN 1868-7075, 01/2016, Volume 8, Issue 1, pp. 11 - 11
Background: Insulin-like growth factors 1 and 2 (IGF1 and IGF2) and their binding proteins (IGFBPs) are expressed in the placenta and known to regulate fetal... 
DNA methylation | Placental expression | Small fetus | Large fetus | Insulin growth factor | HUMAN PLACENTA | FACTOR-II | GENE-EXPRESSION PATTERNS | BIRTH-WEIGHT | IMPRINTED GENES | HORMONE | MESSENGER-RNA | ONCOLOGY | INTRAUTERINE GROWTH | BINDING-PROTEIN 3 | IGF-II | Insulin-Like Growth Factor Binding Protein 3 - genetics | Insulin-Like Growth Factor Binding Proteins - physiology | Insulin-Like Growth Factor II - physiology | Humans | Fetal Growth Retardation - genetics | Insulin-Like Growth Factor I - genetics | Promoter Regions, Genetic - genetics | Case-Control Studies | DNA Methylation | Insulin-Like Growth Factor II - genetics | Fetal Growth Retardation - etiology | Adult | Female | Insulin-Like Growth Factor Binding Protein 4 - physiology | Insulin-Like Growth Factor Binding Protein 2 - physiology | Infant, Newborn | Insulin-Like Growth Factor Binding Protein 3 - physiology | Insulin-Like Growth Factor Binding Proteins - genetics | Insulin-Like Growth Factor Binding Protein 1 - physiology | Insulin-Like Growth Factor Binding Protein 4 - genetics | Insulin-Like Growth Factor Binding Protein 2 - genetics | Placenta - metabolism | Pregnancy | Insulin-Like Growth Factor I - physiology | Infant, Small for Gestational Age | Insulin-Like Growth Factor Binding Protein 1 - genetics | Infants (Newborn) | Epigenetic inheritance | RNA | Growth | Genes | Gene expression | Purines | Pyrimidines | Fetus | Binding proteins | Methylation | Protein binding | Index Medicus
Journal Article