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PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, pp. e77468 - e77468
Diabetic nephropathy is the most common cause of chronic kidney failure and end-stage renal disease in the Western World. One of the major characteristics of... 
MESSENGER-RNAS | SMAD PROTEINS | HB-EGF | INTRONIC MICRORNAS | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | KINASE | EXPRESSION | STAGE RENAL-DISEASE | PHYSICAL INTERACTION | BETA | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Humans | Transforming Growth Factor beta1 - metabolism | Extracellular Matrix - metabolism | MicroRNAs - metabolism | Mesangial Cells - drug effects | Plasminogen Activator Inhibitor 1 - metabolism | Plasminogen Activator Inhibitor 1 - genetics | Epithelial Cells - cytology | Transforming Growth Factor beta1 - pharmacology | Diabetic Nephropathies - pathology | Kidney Tubules, Proximal - pathology | Signal Transduction | Diabetic Nephropathies - metabolism | Cells, Cultured | Gene Expression Regulation | Diabetic Nephropathies - genetics | Mesangial Cells - cytology | Glucose - pharmacology | Transforming Growth Factor beta1 - genetics | Mesangial Cells - metabolism | Fibronectins - metabolism | Proteins - genetics | Proteins - metabolism | RNA, Long Noncoding | Kidney Tubules, Proximal - metabolism | Fibronectins - genetics | MicroRNAs - genetics | Extracellular Matrix - pathology | Type 2 diabetes | Fibronectins | Epigenetic inheritance | Genes | Development and progression | Glucose | Transforming growth factors | Dextrose | MicroRNA | Chronic kidney failure | Bone morphogenetic proteins | Lymphomas | Methylation | End-stage renal disease | Pathogenesis | Genomics | Kinases | Accumulation | Fibronectin | Proteins | Ultrasonic imaging | Rodents | DNA methylation | Mesangial cells | Extracellular matrix | Plasmacytoma | Growth factors | Deoxyribonucleic acid--DNA | Translocation | Transforming growth factor-b1 | Diabetes mellitus | Polyamide-imides | MiRNA | Chromosome 5 | Gene expression | Studies | Nephropathy | Ribonucleic acids | MicroRNAs | Plasminogen activator inhibitors | Renal failure | Epigenetics | Regulation | Kidney diseases | Diabetes | Non-coding RNA | Binding sites | Metabolic disorders | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Blood, ISSN 0006-4971, 08/2014, Volume 124, Issue 7, pp. 1099 - 1109
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2015, Volume 112, Issue 15, pp. E1888 - E1897
Posttranscriptional regulation is a major mechanism to rewire transcriptomes during differentiation. Heterogeneous nuclear RNA-binding protein LL (hnRNPLL) is... 
Plasma cells | Alternative splicing | PAR-CLIP | HnRNP | Rna binding proteins | hnRNP | alternative splicing | RIBONUCLEOPROTEIN | MULTIDISCIPLINARY SCIENCES | plasma cells | MICRORNA TARGET SITES | CLIP | REPRESSION | GENE | AUTOIMMUNITY | SWITCH | CD45 | EXPRESSION | T-CELLS | RNA binding proteins | Nucleotide Motifs - genetics | Transcriptome | 3' Untranslated Regions - genetics | Plasmacytoma - genetics | Plasmacytoma - pathology | RNA, Messenger - metabolism | Plasmacytoma - metabolism | RNA - genetics | Cell Differentiation - genetics | RNA Splicing | RNA Interference | Base Sequence | Plasma Cells - metabolism | RNA Precursors - metabolism | B-Lymphocytes - metabolism | RNA - metabolism | Introns - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | RNA Precursors - genetics | Binding Sites - genetics | RNA Stability | Reverse Transcriptase Polymerase Chain Reaction | Heterogeneous-Nuclear Ribonucleoproteins - genetics | Animals | Cell Line, Tumor | Protein Binding | Messenger RNA | Genetic research | Genetic aspects | Research | Properties | Binding proteins | Cell differentiation | RNA splicing | Proteins | Plasma | Lymphocytes | T cell receptors | Lymphomas | Ribonucleic acid--RNA | Binding sites | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, pp. e18671 - e18671
We previously observed association between variants in the plasmacytoma variant translocation 1 gene (PVT1) and end-stage renal disease (ESRD) attributed to... 
TGF-BETA | HUMAN MESANGIAL CELLS | MESSENGER-RNA | PIMA-INDIANS | MULTIDISCIPLINARY SCIENCES | ANGIOTENSIN-II | HIGH-GLUCOSE | MICRORNAS | KIDNEY | MAMMALIAN-CELLS | STAGE RENAL-DISEASE | Extracellular Matrix - drug effects | Extracellular Matrix Proteins - genetics | Humans | RNA, Messenger - genetics | Transforming Growth Factor beta1 - metabolism | Extracellular Matrix - metabolism | Diabetic Nephropathies - genetics | Glucose - pharmacology | Transforming Growth Factor beta1 - genetics | Mesangial Cells - metabolism | RNA, Messenger - metabolism | Gene Knockdown Techniques | Mesangial Cells - drug effects | Gene Expression Regulation - drug effects | Proteins - genetics | Proteins - metabolism | Plasminogen Activator Inhibitor 1 - metabolism | Models, Biological | RNA, Long Noncoding | Mesangial Cells - pathology | Plasminogen Activator Inhibitor 1 - genetics | Extracellular Matrix Proteins - metabolism | Type 2 diabetes | Fibronectins | Messenger RNA | Chronic kidney failure | Analysis | Genes | Diabetic nephropathies | Development and progression | Lymphomas | Plasmacytoma | Glucose | Dextrose | End-stage renal disease | Regulators | Genomics | Transforming growth factor-a | mRNA | Kinases | Fibronectin | Proteins | Rodents | Mesangial cells | Extracellular matrix | Collagen (type IV) | Enzyme-linked immunosorbent assay | Translocation | Transforming growth factor-b1 | RNA-mediated interference | Diabetes mellitus | Polyamide-imides | Gene expression | Molecular modelling | Nephropathy | Ribonucleic acids | Collagen | Plasminogen activator inhibitors | Kidney diseases | Clear cell-type renal cell carcinoma | Kidney transplantation | Index Medicus
Journal Article
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2004, Volume 173, Issue 2, pp. 1158 - 1165
We have identified two intronic regions of mouse prdm1, the gene encoding B lymphocyte-induced maturation protein-1 (Blimp-1), which confer transcriptional... 
GERMINAL-CENTER FORMATION | GENE | NEGATIVE AUTOREGULATION | BLIMP-1 EXPRESSION | IN-VIVO | C-MYC | B-CELL DIFFERENTIATION | TERMINAL DIFFERENTIATION | IMMUNOLOGY | LYMPHOCYTE DIFFERENTIATION | TRANSCRIPTIONAL REPRESSOR | Proto-Oncogene Proteins - metabolism | Humans