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1. Full Text Alginate/CaCO3 Hybrid Nanoparticles for Efficient Codelivery of Antitumor Gene and Drug
by Zhao, Dong and Liu, Chuan-Jun and Zhuo, Ren-Xi and Cheng, Si-Xue
Molecular pharmaceutics, ISSN 1543-8384, 10/2012, Volume 9, Issue 10, pp. 2887 - 2893
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Nanoparticles - chemistry | Apoptosis - drug effects | Humans | Drug Carriers - administration & dosage | Hexuronic Acids - administration & dosage | Doxorubicin - chemistry | Antineoplastic Agents - administration & dosage | Calcium Carbonate - chemistry | Drug Carriers - chemistry | Plasmids - genetics | Calcium Carbonate - administration & dosage | Glucuronic Acid - administration & dosage | DNA Adducts - administration & dosage | Glucuronic Acid - chemistry | Doxorubicin - administration & dosage | Gene Transfer Techniques | DNA Adducts - chemistry | DNA - administration & dosage | Hexuronic Acids - chemistry | Antineoplastic Agents - chemistry | Alginates - administration & dosage | DNA - chemistry | Alginates - chemistry | Plasmids - chemistry | Cell Line, Tumor | Nanoparticles - administration & dosage | HeLa Cells | Drug Delivery Systems - methods | Plasmids - administration & dosage | Index Medicus
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2. Full Text DNA-based therapeutics and DNA delivery systems: A comprehensive review
by Patil, Siddhesh D and Rhodes, David G and Burgess, Diane J
The AAPS journal, ISSN 1522-1059, 3/2005, Volume 7, Issue 1, pp. E61 - E77
Biotechnology | liposomes | Pharmacy | DNA delivery systems | gene therapy | Pharmacology/Toxicology | nonviral vectors | nucleic acid therapeutics | viral vectors | Nonviral vectors | Nucleic acid therapeutics | Viral vectors | Liposomes | Gene therapy | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Genetic Vectors - administration & dosage | Liposomes - administration & dosage | DNA, Recombinant - administration & dosage | Humans | DNA - therapeutic use | DNA, Catalytic - administration & dosage | Aptamers, Nucleotide - administration & dosage | DNA, Recombinant - therapeutic use | Genetic Vectors - therapeutic use | RNA, Catalytic - pharmacokinetics | DNA, Catalytic - pharmacokinetics | Drug Delivery Systems | Antisense Elements (Genetics) - pharmacokinetics | Biological Transport | Drug Design | Plasmids - genetics | Antisense Elements (Genetics) - therapeutic use | RNA, Catalytic - administration & dosage | Dosage Forms | Transgenes | DNA - pharmacokinetics | DNA, Recombinant - genetics | DNA, Catalytic - therapeutic use | Genes, Transgenic, Suicide | DNA, Recombinant - pharmacokinetics | RNA, Small Interfering - pharmacokinetics | DNA - administration & dosage | Aptamers, Nucleotide - therapeutic use | Plasmids - therapeutic use | RNA, Catalytic - therapeutic use | DNA - genetics | RNA, Small Interfering - therapeutic use | Aptamers, Nucleotide - pharmacokinetics | Antisense Elements (Genetics) - administration & dosage | Genetic Vectors - pharmacokinetics | Liposomes - classification | RNA, Small Interfering - administration & dosage | Plasmids - administration & dosage | Genetic Therapy - methods | Index Medicus
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3. Full Text Intrarectal administration of mCRAMP-encoding plasmid reverses exacerbated colitis in Cnlp-/- mice
by Tai, E.K.K and Wu, W.K.K and Wang, X.J and Wong, H.P.S and Yu, L and Li, Z.J and Lee, C.W and Wong, C.C.M and Yu, J and Sung, J.J.Y and Gallo, R.L and Cho, C.H
Gene therapy, ISSN 0969-7128, 02/2013, Volume 20, Issue 2, pp. 187 - 193
Cathelicidin | Mucin | IL-1 | TNF | Antimicrobial peptide | Ulcerative colitis | Tumor Necrosis Factor-alpha - metabolism | Genetic Therapy | Gene Expression | Tumor Necrosis Factor-alpha - genetics | Colitis, Ulcerative - genetics | Administration, Rectal | Interleukin-1beta - genetics | Mice, Knockout | Animals | Interleukin-1beta - metabolism | Mucins - metabolism | Plasmids - genetics | Colitis, Ulcerative - therapy | Peroxidase - genetics | Mice | Antimicrobial Cationic Peptides - genetics | Genetic Vectors | Mucins - genetics | Plasmids - administration & dosage | Apoptosis | Intestinal Mucosa - pathology | Peroxidase - metabolism | Inflammatory bowel disease | Immunology | Peptides | Gene therapy | Cells | Index Medicus
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4. Full Text INF-γ encoding plasmid administration triggers bone loss and disrupts bone marrow microenvironment
by Agas, Dimitrios and Gusmão Silva, Guilherme and Laus, Fulvio and Marchegiani, Andrea and Capitani, Melania and Vullo, Cecilia and Catone, Giuseppe and Lacava, Giovanna and Concetti, Antonio and Marchetti, Luigi and Sabbieti, Maria Giovanna
Journal of endocrinology, ISSN 0022-0795, 02/2017, Volume 232, Issue 2, pp. 309 - 321
Editor's Choice | Bone marrow | Plasmid DNA | INF-γ bone loss | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Ovariectomy | Bone Marrow Cells - pathology | Cells, Cultured | Bone Diseases, Metabolic - pathology | Bone Remodeling - drug effects | Bone Diseases, Metabolic - metabolism | Bone Density - drug effects | Animals | Bone Marrow - metabolism | Interferon-gamma - administration & dosage | Bone Marrow Cells - drug effects | Female | Mice | Bone Marrow Cells - metabolism | Bone Marrow - drug effects | CXCL12 protein | Mesenchyme | Cytokines | Bone remodelling | Stem cell transplantation | Homeostasis | Inflammation | Bone (trabecular) | Rodents | γ-Interferon | Stem cells | Bone mineral density | Interferon | Bone loss | Bone (cortical) | Osteopenia | Index Medicus
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5. Full Text Dextran–protamine–solid lipid nanoparticles as a non-viral vector for gene therapy: In vitro characterization and in vivo transfection after intravenous administration to mice
by Delgado, Diego and Gascón, Alicia Rodríguez and del Pozo-Rodríguez, Ana and Echevarría, Enrique and Ruiz de Garibay, Aritz Pérez and Rodríguez, Juan Manuel and Solinís, Maria Ángeles
International journal of pharmaceutics, ISSN 0378-5173, 04/2012, Volume 425, Issue 1-2, pp. 35 - 43
Endocytosis | Non-viral vectors | Gene therapy | Solid lipid nanoparticles | Intracellular trafficking | In vivo transfection | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Hemolysis - drug effects | Injections, Intravenous | Genetic Vectors - administration & dosage | Nanoparticles - chemistry | Humans | Dextrans - chemistry | Green Fluorescent Proteins - genetics | Transfection | HEK293 Cells | Erythrocytes - pathology | Protamines - administration & dosage | Female | Diglycerides - administration & dosage | Cell Line | Protamines - chemistry | Genetic Vectors - chemistry | Endocytosis - drug effects | DNA - administration & dosage | Erythrocytes - drug effects | DNA - chemistry | Animals | Mice, Nude | Diglycerides - chemistry | Hemagglutination - drug effects | Plasmids - chemistry | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Dextrans - administration & dosage | Plasmids - administration & dosage | Genetic Therapy - methods | Nanoparticles | Genetic vectors | Genes | Genetic aspects | Universities and colleges | Virus diseases | Dextran | Drugstores | Index Medicus | Spleen | Clathrin | Particle size | Surface charge | Intravenous administration | Caveolae | Gene transfer | Liver | Lung | Erythrocytes | Lipids | protamine | nanoparticles | Plasmids | Green fluorescent protein | Agglutination | Expression vectors
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6. Full Text Biodegradable nanoparticles composed of dendrigraft poly-l-lysine for gene delivery
by Kodama, Yukinobu and Nakamura, Tadahiro and Kurosaki, Tomoaki and Egashira, Kanoko and Mine, Toyoharu and Nakagawa, Hiroo and Muro, Takahiro and Kitahara, Takashi and Higuchi, Norihide and Sasaki, Hitoshi
European journal of pharmaceutics and biopharmaceutics, ISSN 0939-6411, 08/2014, Volume 87, Issue 3, pp. 472 - 479
Gene delivery | Biodegradable | Dendrigraft poly-l-lysine | γ-Polyglutamic acid | Nanoparticle | Ternary complex | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Polymers - administration & dosage | Genetic Vectors - administration & dosage | Nanoparticles - chemistry | Polylysine - analogs & derivatives | Melanoma, Experimental - drug therapy | Polylysine - administration & dosage | Erythrocytes | Male | Polyglutamic Acid - administration & dosage | Polylysine - chemistry | Anions - chemistry | Polyglutamic Acid - analogs & derivatives | Transfection - methods | Plasmids - genetics | Anions - administration & dosage | Gene Transfer Techniques | Genetic Vectors - chemistry | Lysine - administration & dosage | Genetic Vectors - genetics | DNA - genetics | Particle Size | Polyglutamic Acid - chemistry | Animals | Melanoma, Experimental - genetics | Cell Line, Tumor | Polymers - chemistry | Mice | Nanoparticles - administration & dosage | Lysine - chemistry | Plasmids - administration & dosage | Genetic Therapy - methods | Lysine | Index Medicus
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7. Full Text Safety and Comparative Immunogenicity of an HIV-1 DNA Vaccine in Combination with Plasmid Interleukin 12 and Impact of Intramuscular Electroporation for Delivery
by Spyros A. Kalams and Scott D. Parker and Marnie Elizaga and Barbara Metch and Srilatha Edupuganti and John Hural and Stephen De Rosa and Donald K. Carter and Kyle Rybczyk and Ian Frank and Jonathan Fuchs and Beryl Koblin and Denny H. Kim and Patrice Joseph and Michael C. Keefer and Lindsey R. Baden and John Eldridge and Jean Boyer and Adam Sherwat and Massimo Cardinali and Mary Allen and Michael Pensiero and Chris Butler and Amir S. Khan and Jian Yan and Niranjan Y. Sardesai and James G. Kublin and David B. Weiner and NIAID HIV Vaccine Trials Network and the NIAID HIV Vaccine Trials Network
The Journal of infectious diseases, ISSN 0022-1899, 9/2013, Volume 208, Issue 5, pp. 818 - 829
T lymphocytes | HIV/AIDS | Body mass index | Immune response | HIV | Interleukins | Plasmids | Vaccination | Electroporation | DNA vaccines | HIV 1 | plasmid cytokine adjuvant | electroporation | vaccination | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Miscellaneous | Infectious diseases | Biological and medical sciences | Medical sciences | Virology | Adjuvants, Immunologic - administration & dosage | Interleukin-12 - genetics | Humans | Middle Aged | AIDS Vaccines - immunology | Male | DNA - adverse effects | AIDS Vaccines - adverse effects | CD4-Positive T-Lymphocytes - immunology | Young Adult | Vaccination - methods | Adjuvants, Immunologic - genetics | Adult | Female | Drug Administration Routes | DNA - immunology | DNA - administration & dosage | HIV-1 - genetics | HIV-1 - immunology | Interleukin-12 - administration & dosage | Adolescent | AIDS Vaccines - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Cytokines - biosynthesis | Usage | AIDS vaccines | Interleukin-12 | Dosage and administration | Research | Human immunogenetics | Index Medicus | Abridged Index Medicus | Major and Brief Reports
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8. Full Text Comparison of lacZ reporter gene expression in gilthead sea bream (Sparus aurata) following oral or intramuscular administration of plasmid DNA in chitosan nanoparticles
by Sáez, M.I and Vizcaíno, A.J and Alarcón, F.J and Martínez, T.F
Aquaculture, ISSN 0044-8486, 05/2017, Volume 474, pp. 1 - 10
Chitosan-nanoparticles | Transient gene expression | Tissue migration | Sparus aurata | Plasmid DNA | Oral gene delivery | Fisheries | Life Sciences & Biomedicine | Marine & Freshwater Biology | Science & Technology | Nanoparticles | Genetic research | Comparative analysis | Gene expression | Genes | DNA | Anopheles | Gastrointestinal system
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9. Full Text Novel polyethyleneimine-R8-heparin nanogel for high-efficiency gene delivery in vitro and in vivo
by Song, Linjiang and Liang, Xiuqi and Yang, Suleixin and Wang, Ning and He, Tao and Wang, Yan and Zhang, Lan and Wu, Qinjie and Gong, Changyang
Drug delivery, ISSN 1071-7544, 01/2018, Volume 25, Issue 1, pp. 122 - 131
heparin | gene delivery | Nanogel | polyethyleneimine | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cell Line | Gene Transfer Techniques | Apoptosis - drug effects | Colonic Neoplasms - drug therapy | Gels - administration & dosage | HCT116 Cells | Humans | Heparin - administration & dosage | Antineoplastic Agents - administration & dosage | Animals | Transfection - methods | Mice, Nude | Polyethyleneimine - administration & dosage | HEK293 Cells | Cell Line, Tumor | Female | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Oligopeptides - administration & dosage | Cell-Penetrating Peptides - administration & dosage | TNF-Related Apoptosis-Inducing Ligand - genetics | Plasmids - administration & dosage | Genetic Therapy - methods | Peptides | Gene therapy | Apoptosis | Index Medicus | nanogel
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