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Seminars in immunopathology, ISSN 1863-2300, 10/2011, Volume 34, Issue 1, pp. 43 - 62
The interaction of coagulation factors with the perivascular environment affects the development of disease in ways that extend beyond their traditional roles... 
Autoimmunity | Complement receptor 3 | Multiple sclerosis | Stroke | Alzheimer’s disease | Internal Medicine | Macrophages | Blood brain barrier | Inflammatory disease | Microglia | Biomedicine | Immunology | Rheumatoid arthritis | CD11b/CD18 | Atherosclerosis | Plasminogen | Anticoagulant therapy | Alzheimer's disease | Pathology | Life Sciences & Biomedicine | Science & Technology | Colitis - genetics | Humans | Brain Injuries - metabolism | Arthritis, Rheumatoid - metabolism | Bacterial Infections - genetics | Inflammation - metabolism | Blood Coagulation - immunology | Muscular Dystrophy, Duchenne - immunology | Alzheimer Disease - immunology | Fibrinogen - immunology | Thromboplastin - immunology | Pulmonary Fibrosis - immunology | Vascular Diseases - genetics | Brain Injuries - genetics | Thrombin - genetics | Kidney Diseases - immunology | Arthritis, Rheumatoid - genetics | Neoplasms - immunology | Colitis - metabolism | Muscular Dystrophy, Duchenne - genetics | Bacterial Infections - metabolism | Neoplasms - metabolism | Pulmonary Fibrosis - genetics | Spinal Cord Injuries - genetics | Kidney Diseases - genetics | Stroke - genetics | Brain Injuries - immunology | Neoplasms - genetics | Bacterial Infections - immunology | Pulmonary Fibrosis - metabolism | Colitis - immunology | Thrombin - immunology | Stroke - immunology | Kidney Diseases - metabolism | Multiple Sclerosis - metabolism | Vascular Diseases - immunology | Spinal Cord Injuries - metabolism | Multiple Sclerosis - genetics | Inflammation - immunology | Fibrinogen - genetics | Stroke - metabolism | Animals | Thromboplastin - genetics | Alzheimer Disease - metabolism | Fibrinogen - metabolism | Inflammation - genetics | Multiple Sclerosis - immunology | Blood Coagulation - genetics | Spinal Cord Injuries - immunology | Muscular Dystrophy, Duchenne - metabolism | Thrombin - metabolism | Thromboplastin - metabolism | Alzheimer Disease - genetics | Arthritis, Rheumatoid - immunology | Vascular Diseases - metabolism | Nervous system diseases | Bacterial infections | Oncology, Experimental | Thrombin | Inflammation | Anticoagulants (Medicine) | Research | Rheumatoid factor | Fibrin | Fibrinogen | Genetic research | Colitis | Cancer | Index Medicus | Traumatic brain injury | Coagulation | Tissue factor | hemostasis | Spinal cord injury | Inflammatory diseases | Kidney | Signal transduction | Duchenne's muscular dystrophy | Neurodegenerative diseases | Therapeutic applications | Thrombosis | Coagulation factors | Infection | Molecular modelling | Fibrosis | Brain injury
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 04/2010, Volume 103, Issue 4, pp. 788 - 796
CD40L figures prominently in atherogenesis. Recent data demonstrate elevated levels of sCD40L in the serum of patients with the metabolic syndrome (MS). This... 
metabolic syndrome | CD40L | preadipocytes | inflammation | adipocytes | Cardiovascular Biology and Cell Signalling | Preadipocytes | Inflammation | Adipocytes | Metabolic syndrome | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Obesity - immunology | CD40 Ligand - blood | Humans | Metabolic Syndrome - metabolism | NF-kappa B - metabolism | PPAR gamma - metabolism | RNA, Messenger - metabolism | Cardiovascular Diseases - genetics | Obesity - genetics | Case-Control Studies | Inflammation - metabolism | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Plasminogen Activator Inhibitor 1 - metabolism | Time Factors | Interleukin-6 - blood | Inflammation Mediators - metabolism | Chemokine CCL2 - metabolism | Metabolic Syndrome - immunology | Interleukin-8 - metabolism | Adipocytes - immunology | Adipogenesis | CCAAT-Enhancer-Binding Proteins - metabolism | Recombinant Proteins - metabolism | Cardiovascular Diseases - metabolism | Signal Transduction | Endothelial Cells - metabolism | Inflammation - immunology | 3T3-L1 Cells | Obesity - metabolism | Endothelial Cells - immunology | Cardiovascular Diseases - immunology | Animals | CD40 Ligand - genetics | Metabolic Syndrome - genetics | Adipocytes - metabolism | Inflammation - genetics | Mice | Culture Media, Conditioned - metabolism | Mitogen-Activated Protein Kinases - metabolism
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2005, Volume 280, Issue 46, pp. 38247 - 38258
Journal Article
Aging cell, ISSN 1474-9718, 08/2015, Volume 14, Issue 4, pp. 644 - 658
Summary The healthspan of mice is enhanced by killing senescent cells using a transgenic suicide gene. Achieving the same using small molecules would have a... 
dasatinib | plasminogen‐activated inhibitor | dependence receptors | quercetin | ephrins | PI3K delta | p21 | Dasatinib | Dependence receptors | Ephrins | Plasminogen-activated inhibitor | Quercetin | P21 | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Cell Biology | Carotid Arteries - drug effects | Endonucleases - genetics | Plasminogen Activator Inhibitor 2 - genetics | Transcriptome | Gene Expression Profiling | Adipocytes - drug effects | Aging - genetics | Osteoporosis - metabolism | Ephrins - metabolism | Plasminogen Activator Inhibitor 2 - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Osteoporosis - genetics | Intervertebral Disc - pathology | Fibroblasts - metabolism | Endothelial Cells - metabolism | Intervertebral Disc - chemistry | Fibroblasts - pathology | Mesenchymal Stem Cells - pathology | Mice, Knockout | Dasatinib - pharmacology | Osteoporosis - pathology | Ephrins - genetics | Fibroblasts - drug effects | Mice | Endothelial Cells - pathology | bcl-X Protein - metabolism | Aging - metabolism | Aging - drug effects | bcl-X Protein - genetics | Cellular Senescence - drug effects | Phosphatidylinositol 3-Kinases - metabolism | Endonucleases - metabolism | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Mesenchymal Stem Cells - drug effects | Mesenchymal Stem Cells - metabolism | Heart - physiopathology | Cellular Senescence - genetics | Osteoporosis - prevention & control | DNA-Binding Proteins - genetics | Adipocytes - pathology | Aging - pathology | Phosphatidylinositol 3-Kinases - genetics | Animals | Quercetin - pharmacology | Adipocytes - metabolism | Heart - drug effects | Carotid Arteries - pathology | Intervertebral Disc - drug effects | Drug Combinations | Endothelial Cells - drug effects | Index Medicus | Original | plasminogen-activated inhibitor
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2007, Volume 98, Issue 3, pp. 512 - 520
Journal Article