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Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6061, pp. 1372 - 1377
Most malaria drug development focuses on parasite stages detected in red blood cells, even though, to achieve eradication, next-generation drugs active against... 
Schizonts | Malaria | RESEARCH ARTICLES | Liver | Antimalarials | Infections | Parasites | Inhibitory concentration 50 | Scaffolds | Blood | Chemicals | INFECTIONS | FALCIPARUM | MULTIDISCIPLINARY SCIENCES | METHEMOGLOBINEMIA | RESISTANCE | MALARIA | TARGETS | MUTATIONS | Plasmodium berghei - physiology | Humans | Imidazoles - chemistry | Plasmodium - physiology | Piperazines - chemistry | Plasmodium falciparum - drug effects | Plasmodium - growth & development | Imidazoles - therapeutic use | Plasmodium falciparum - physiology | Antimalarials - pharmacokinetics | Antimalarials - therapeutic use | Imidazoles - pharmacology | Piperazines - therapeutic use | Random Allocation | Piperazines - pharmacology | Plasmodium berghei - cytology | Small Molecule Libraries | Malaria - parasitology | Cell Line, Tumor | Plasmodium berghei - growth & development | Mice | Mice, Inbred BALB C | Liver - parasitology | Erythrocytes - parasitology | Plasmodium berghei - drug effects | Plasmodium - cytology | Plasmodium falciparum - cytology | Plasmodium - drug effects | Imidazoles - pharmacokinetics | Plasmodium yoelii - growth & development | Protozoan Proteins - genetics | Sporozoites - growth & development | Protozoan Proteins - metabolism | Plasmodium yoelii - drug effects | Protozoan Proteins - chemistry | Molecular Structure | Piperazines - pharmacokinetics | Drug Evaluation, Preclinical | Sporozoites - drug effects | Drug Resistance | Plasmodium yoelii - physiology | Plasmodium yoelii - cytology | Drug Discovery | Antimalarials - pharmacology | Malaria - prevention & control | Animals | Antimalarials - chemistry | Polymorphism, Single Nucleotide | Malaria - drug therapy | Plasmodium falciparum - growth & development | Pharmaceutical research | Plasmodium | Care and treatment | Analysis | Research | Drug therapy
Journal Article
Science, ISSN 0036-8075, 1/2005, Volume 307, Issue 5706, pp. 82 - 86
Plasmodium berghei and Plasmodium chabaudi are widely used model malaria species. Comparison of their genomes, integrated with proteomic and microarray data,... 
Transcriptomes | Malaria | Genes | Rodents | Sporozoites | Genomes | Parasites | Gametocytes | Proteomes | Ookinetes | Research Article | PROTEIN FAMILY | FALCIPARUM | MULTIDISCIPLINARY SCIENCES | SEQUENCE | MOUSE | GENE FAMILY | MALARIA | SPOROZOITES | BERGHEI | SELECTION | EXPRESSION | RNA, Protozoan - genetics | Plasmodium chabaudi - growth & development | Genome, Protozoan | Oligonucleotide Array Sequence Analysis | Plasmodium berghei - genetics | Genes, Protozoan | Gene Expression Profiling | Plasmodium yoelii - growth & development | RNA, Messenger - metabolism | Plasmodium yoelii - metabolism | Life Cycle Stages | Plasmodium falciparum - genetics | Plasmodium - growth & development | Plasmodium falciparum - metabolism | Transcription, Genetic | 3' Untranslated Regions | Anopheles - parasitology | Plasmodium - genetics | Plasmodium - metabolism | RNA, Messenger - genetics | Computational Biology | Gene Silencing | Selection, Genetic | Proteome - analysis | Plasmodium chabaudi - metabolism | Plasmodium yoelii - genetics | RNA, Protozoan - metabolism | Plasmodium berghei - metabolism | Animals | Plasmodium chabaudi - genetics | Malaria - parasitology | Proteomics | Plasmodium berghei - growth & development | Plasmodium falciparum - growth & development | Protozoan Proteins - analysis | Evolution, Molecular | Plasmodium | Genetic aspects | Research | Parasitic protozoa | Comparative analysis | Genomics
Journal Article
Journal Article
International Journal for Parasitology, ISSN 0020-7519, 10/2016, Volume 46, Issue 11, pp. 685 - 696
Journal Article
Nature, ISSN 0028-0836, 2015, Volume 522, Issue 7556, pp. 315 - 320
Journal Article
Malaria Journal, ISSN 1475-2875, 2009, Volume 8, Issue 1, pp. 86 - 86
Journal Article
Nature, ISSN 0028-0836, 02/2016, Volume 530, Issue 7589, pp. 233 - 236
The proteasome is a multi-component protease complex responsible for regulating key processes such as the cell cycle and antigen presentation(1). Compounds... 
VISUALIZATION | FALCIPARUM MALARIA | MECHANISM | SPECIFICITY | ARTEMISININ RESISTANCE | MULTIDISCIPLINARY SCIENCES | VALIDATION | ELECTRON-MICROSCOPY | IDENTIFICATION | PARASITE | HUMAN 20S PROTEASOME | Plasmodium falciparum - enzymology | Plasmodium - enzymology | Plasmodium chabaudi - enzymology | Species Specificity | Humans | Proteasome Inhibitors - chemistry | Plasmodium - drug effects | Plasmodium falciparum - drug effects | Protein Subunits - metabolism | Dose-Response Relationship, Drug | Artemisinins - pharmacology | Plasmodium chabaudi - physiology | Drug Design | Plasmodium - growth & development | Female | Drug Resistance | Antimalarials - adverse effects | Catalytic Domain | Proteasome Inhibitors - pharmacology | Models, Molecular | Proteasome Endopeptidase Complex - chemistry | Proteasome Inhibitors - toxicity | Proteasome Inhibitors - adverse effects | Antimalarials - pharmacology | Cryoelectron Microscopy | Drug Synergism | Animals | Substrate Specificity - drug effects | Proteasome Endopeptidase Complex - ultrastructure | Antimalarials - chemistry | Plasmodium chabaudi - drug effects | Mice | Mice, Inbred BALB C | Protein Subunits - antagonists & inhibitors | Protein Subunits - chemistry | Antimalarials - toxicity | Enzyme Activation | Plasmodium falciparum - growth & development | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-proteasome system | Plasmodium | Health aspects | Proteins | Malaria | Protease inhibitors | Proteases | Erythrocytes | Ligands | Parasites | Drug dosages
Journal Article
Malaria Journal, ISSN 1475-2875, 11/2016, Volume 15, Issue 1, pp. 1 - 10
Background: The Greater Mekong Subregion is aiming to achieve regional malaria elimination by 2030. Though a shift in malaria parasite species predominance by... 
Plasmodium falciparum | Plasmodium vivax | Prevalence | Molecular identification | Plasmodium ovale | Genetic diversity | Plasmodium malariae | THYMIDYLATE SYNTHASE GENE | INFECTIOUS DISEASES | SEQUENCE VARIATION | PYRIMETHAMINE RESISTANCE | REPUBLIC-OF-CHINA | TROPICAL MEDICINE | POLYMERASE-CHAIN-REACTION | DIHYDROFOLATE-REDUCTASE | RIBOSOMAL-RNA GENE | IMPORTED MALARIA | HIGH PREVALENCE | RAPID DIAGNOSTIC-TESTS | PARASITOLOGY | Plasmodium vivax - classification | Humans | Plasmodium vivax - genetics | Male | Phylogeny | Protozoan Proteins - genetics | DNA, Ribosomal - chemistry | Plasmodium ovale - isolation & purification | Genetic Variation | Young Adult | Plasmodium falciparum - classification | Malaria - epidemiology | Plasmodium falciparum - genetics | Plasmodium falciparum - isolation & purification | Polymerase Chain Reaction | Adult | Female | Plasmodium ovale - genetics | DNA, Protozoan - chemistry | Child | Plasmodium ovale - classification | Drug Resistance | DNA, Ribosomal - genetics | Plasmodium malariae - classification | Cross-Sectional Studies | RNA, Ribosomal, 18S - genetics | Plasmodium malariae - isolation & purification | China - epidemiology | Sequence Analysis, DNA | Microscopy | Malaria - parasitology | Myanmar - epidemiology | Plasmodium vivax - isolation & purification | DNA, Protozoan - genetics | Plasmodium malariae - genetics | Cluster Analysis | Control | Care and treatment | Disease transmission | Malaria | Research | Genetic polymorphisms | Biological diversity
Journal Article