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1. Full Text The Plasmodium translocon of exported proteins (PTEX) component thioredoxin‐2 is important for maintaining normal blood‐stage growth
by Matthews, Kathryn and Kalanon, Ming and Chisholm, Scott A and Sturm, Angelika and Goodman, Christopher D and Dixon, Matthew W. A and Sanders, Paul R and Nebl, Thomas and Fraser, Fiona and Haase, Silvia and McFadden, Geoffrey I and Gilson, Paul R and Crabb, Brendan S and Koning‐Ward, Tania F
Molecular microbiology, ISSN 0950-382X, 09/2013, Volume 89, Issue 6, pp. 1167 - 1186
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virulence Factors - genetics | Malaria, Cerebral - parasitology | Mice, Inbred C57BL | Plasmodium berghei - genetics | Virulence | Animals | Thioredoxins - genetics | Gene Deletion | Plasmodium berghei - enzymology | Survival Analysis | Parasitemia - parasitology | Plasmodium berghei - growth & development | Thioredoxins - metabolism | Virulence Factors - metabolism | Mice | Mice, Inbred BALB C | Plasmodium berghei - pathogenicity | Disease Models, Animal | Malaria | Thioredoxin | Growth | Analysis | Proteins | Survival analysis | Parasitology | Parasites | Molecular biology | Bacterial proteins | Index Medicus
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2. Full Text Upregulation of TGF-β, FOXP3, and CD4 +CD25 + Regulatory T Cells Correlates with More Rapid Parasite Growth in Human Malaria Infection
by Walther, Michael and Tongren, Jon Eric and Andrews, Laura and Korbel, Daniel and King, Elizabeth and Fletcher, Helen and Andersen, Rikke F and Bejon, Philip and Thompson, Fiona and Dunachie, Susanna J and Edele, Fanny and de Souza, J. Brian and Sinden, Robert E and Gilbert, Sarah C and Riley, Eleanor M and Hill, Adrian V.S
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2005, Volume 23, Issue 3, pp. 287 - 296
Life Sciences & Biomedicine | Immunology | Science & Technology | Transforming Growth Factor beta - immunology | CD4 Antigens - immunology | Up-Regulation | DNA-Binding Proteins - immunology | Humans | T-Lymphocytes - parasitology | Clinical Trials as Topic | Plasmodium falciparum - immunology | Receptors, Interleukin-2 - immunology | Transforming Growth Factor beta - blood | DNA-Binding Proteins - metabolism | Malaria, Falciparum - parasitology | Animals | Malaria, Falciparum - immunology | T-Lymphocytes - immunology | Forkhead Transcription Factors | Index Medicus
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3. Full Text Placental Malaria-Associated Inflammation Disturbs the Insulin-like Growth Factor Axis of Fetal Growth Regulation
by Alexandra J. Umbers and Philippe Boeuf and Caroline Clapham and Danielle I. Stanisic and Francesca Baiwog and Ivo Mueller and Peter Siba and Christopher L. King and James G. Beeson and Jocelyn Glazier and Stephen J. Rogerson
The Journal of infectious diseases, ISSN 0022-1899, 2/2011, Volume 203, Issue 4, pp. 561 - 569
Women | Pregnancy | PARASITES | Somatomedins | Monocytes | Placenta | Malaria | Birth weight | Infants | Inflammation | Infections | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Infectious diseases | Parasitic diseases | Protozoal diseases | Biological and medical sciences | Human protozoal diseases | Medical sciences | Papua New Guinea | RNA, Messenger - isolation & purification | Humans | Malaria, Falciparum - pathology | RNA, Messenger - genetics | Insulin-Like Growth Factor Binding Proteins - blood | Gene Expression Profiling | Insulin-Like Growth Factor I - analysis | Pregnancy Complications, Infectious - pathology | Fetal Growth Retardation - pathology | Insulin-Like Growth Factor II - analysis | Plasma - chemistry | Placenta - pathology | Insulin-Like Growth Factor Binding Protein 3 | Plasmodium falciparum - pathogenicity | Adult | Female | Insulin-Like Growth Factor Binding Protein 1 - blood | Complications and side effects | Growth | Physiological aspects | Fetus | Research | Insulin-like growth factor 1 | Risk factors | Index Medicus | Abridged Index Medicus | Major and Brief Reports
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4. Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites
by Raphemot, Rene and Eubanks, Amber Leigh and Toro-Moreno, Maria and Geiger, Rechel Anne and Hughes, Philip Floyd and Lu, Kuan-Yi and Haystead, Timothy Arthur James and Derbyshire, Emily Rose
Cell chemical biology, ISSN 2451-9456, 03/2019, Volume 26, Issue 3, pp. 411 - 419.e7
high-throughput screen | Plasmodium | kinase | malaria | atypical kinase | PK9 | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Kinases - metabolism | Cell Line | Antimalarials - metabolism | Protozoan Proteins - antagonists & inhibitors | Humans | Plasmodium - metabolism | Protein Kinases - chemistry | Plasmodium - drug effects | Benzimidazoles - chemistry | Antimalarials - pharmacology | Hepatocytes - parasitology | Life Cycle Stages | Hepatocytes - cytology | Protozoan Proteins - metabolism | Ubiquitination - drug effects | Protein Processing, Post-Translational - drug effects | Ubiquitin-Conjugating Enzymes - metabolism | Benzimidazoles - metabolism | Antimalarials - chemistry | Benzimidazoles - pharmacology | Benzamides - pharmacology | Benzamides - chemistry
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5. Full Text Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
by Stephan Meister and David M. Plouffe and Kelli L. Kuhen and Ghislain M. C. Bonamy and Tao Wu and S. Whitney Barnes and Selina E. Bopp and Rachel Borboa and A. Taylor Bright and Jianwei Che and Steve Cohen and Neekesh V. Dharia and Kerstin Gagaring and Montip Gettayacamin and Perry Gordon and Todd Groessl and Nobutaka Kato and Marcus C. S. Lee and Case W. McNamara and David A. Fidock and Advait Nagle and Tae-gyu Nam and Wendy Richmond and Jason Roland and Matthias Rottmann and Bin Zhou and Patrick Froissard and Richard J. Glynne and Dominique Mazier and Jetsumon Sattabongkot and Peter G. Schultz and Tove Tuntland and John R. Walker and Yingyao Zhou and Arnab Chatterjee and Thierry T. Diagana and Elizabeth A. Winzeler
Science (American Association for the Advancement of Science), ISSN 0036-8075, 12/2011, Volume 334, Issue 6061, pp. 1372 - 1377
Schizonts | Malaria | RESEARCH ARTICLES | Liver | Antimalarials | Infections | Parasites | Inhibitory concentration 50 | Scaffolds | Blood | Chemicals | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Pharmaceutical technology. Pharmaceutical industry | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Plasmodium berghei - physiology | Humans | Imidazoles - chemistry | Plasmodium - physiology | Piperazines - chemistry | Plasmodium falciparum - drug effects | Plasmodium - growth & development | Imidazoles - therapeutic use | Plasmodium falciparum - physiology | Antimalarials - pharmacokinetics | Antimalarials - therapeutic use | Imidazoles - pharmacology | Piperazines - therapeutic use | Random Allocation | Piperazines - pharmacology | Plasmodium berghei - cytology | Small Molecule Libraries | Malaria - parasitology | Cell Line, Tumor | Plasmodium berghei - growth & development | Mice | Mice, Inbred BALB C | Liver - parasitology | Erythrocytes - parasitology | Plasmodium berghei - drug effects | Plasmodium - cytology | Plasmodium falciparum - cytology | Plasmodium - drug effects | Imidazoles - pharmacokinetics | Plasmodium yoelii - growth & development | Protozoan Proteins - genetics | Sporozoites - growth & development | Protozoan Proteins - metabolism | Plasmodium yoelii - drug effects | Protozoan Proteins - chemistry | Molecular Structure | Piperazines - pharmacokinetics | Drug Evaluation, Preclinical | Sporozoites - drug effects | Drug Resistance | Plasmodium yoelii - physiology | Plasmodium yoelii - cytology | Drug Discovery | Antimalarials - pharmacology | Malaria - prevention & control | Animals | Antimalarials - chemistry | Polymorphism, Single Nucleotide | Malaria - drug therapy | Plasmodium falciparum - growth & development | Pharmaceutical research | Plasmodium | Care and treatment | Analysis | Research | Drug therapy | Index Medicus
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6. Full Text Plasmodium falciparum Bloom homologue, a nucleocytoplasmic protein, translocates in 3′ to 5′ direction and is essential for parasite growth
by Rahman, Farhana and Tarique, Mohammed and Tuteja, Renu
Biochimica et biophysica acta. Proteins and proteomics, ISSN 1570-9639, 05/2016, Volume 1864, Issue 5, pp. 594 - 608
DNA helicase | Plasmodium falciparum | Malaria | Repair | Gene disruption | ATPase | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Malaria, Falciparum - enzymology | Plasmodium falciparum - enzymology | Malaria, Falciparum - genetics | RecQ Helicases - metabolism | Humans | Adenosine Triphosphatases - metabolism | RecQ Helicases - genetics | Malaria, Falciparum - parasitology | Animals | Plasmodium falciparum - genetics | RNA, Double-Stranded - genetics | DNA, Protozoan - genetics | Plasmodium falciparum - metabolism | Adenosine Triphosphatases - genetics | RecQ Helicases - chemistry | Plasmodium falciparum - growth & development | Proteins | Parasitic diseases | Growth | Physiological aspects | Adenosine triphosphatase
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7. Full Text Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum
by Engelberg, Klemens and Spielmann, Tobias and Preiser, Peter R and Hu, Guangan and Cheemadan, Sabna and Cabrera, Ana and Mok, Sachel and Chaal, Balbir K and Bozdech, Zbynek and Haase, Silvia and Gilberger, Tim-W and Kono, Maya
Nature biotechnology, ISSN 1087-0156, 01/2010, Volume 28, Issue 1, pp. 91 - 98
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Transcription, Genetic - drug effects | Markov Chains | Humans | Gene Expression Profiling | Plasmodium falciparum - drug effects | Gene Regulatory Networks | Antimalarials - pharmacology | Gene Expression Regulation - drug effects | Malaria, Falciparum - parasitology | Algorithms | Animals | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Merozoites - drug effects | Plasmodium falciparum - pathogenicity | Plasmodium falciparum - growth & development | Merozoites - metabolism | Plasmodium falciparum | Malaria | Growth | Causes of | Genetic aspects | Research | Gene expression | Health aspects | Biotechnology | Parasites | Developmental biology | Index Medicus
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8. Full Text ALBA4 modulates its stage‐specific interactions and specific mRNA fates during Plasmodium yoelii growth and transmission
by Muñoz, Elyse E and Hart, Kevin J and Walker, Michael P and Kennedy, Mark F and Shipley, Mackenzie M and Lindner, Scott E
Molecular microbiology, ISSN 0950-382X, 10/2017, Volume 106, Issue 2, pp. 266 - 284
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Plasmodium yoelii - physiology | Anopheles - parasitology | Transcriptome | Parasites | Plasmodium yoelii - growth & development | RNA, Messenger - metabolism | Plasmodium yoelii - genetics | RNA, Messenger - biosynthesis | Animals | Protozoan Proteins - metabolism | Sporozoites - metabolism | Malaria - parasitology | Proteomics | Parasitic Diseases - genetics | Enzyme Repression | RNA-Binding Proteins - metabolism | Plasmodium falciparum | Mosquitoes | Messenger RNA | Disease transmission | Analysis | Protein binding | Vector-borne diseases | Repressing | RNA-binding protein | Malaria | Aquatic insects | Ribonucleic acid--RNA | Blood | Contamination | Index Medicus
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