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PLoS Pathogens, ISSN 1553-7366, 08/2009, Volume 5, Issue 8, p. e1000559
The intraerythrocytic parasite Plasmodium-the causative agent of malaria-produces an inorganic crystal called hemozoin (Hz) during the heme detoxification... 
APOPTOSIS | INNATE IMMUNE RECEPTORS | INTERLEUKIN-1-BETA | MACROPHAGES | CASPASE-1 INFLAMMASOME | MICROBIOLOGY | KAPPA-B | NALP3 INFLAMMASOME | RESPONSES | VIROLOGY | IN-VIVO | MICE | PARASITOLOGY | Potassium - metabolism | Reactive Oxygen Species - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Protein-Tyrosine Kinases - metabolism | Humans | Caspase 1 - metabolism | Male | Caspase 1 - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Hemeproteins - immunology | Signal Transduction - immunology | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | src-Family Kinases - metabolism | Cytoskeletal Proteins - metabolism | Female | Interleukin-1beta - biosynthesis | Phosphorylation - immunology | Malaria - metabolism | Syk Kinase | Carrier Proteins - immunology | Disease Models, Animal | Neutrophil Infiltration - immunology | Calcium-Binding Proteins - metabolism | Carrier Proteins - physiology | Apoptosis Regulatory Proteins - immunology | Plasmodium chabaudi - chemistry | Hemeproteins - metabolism | Malaria - immunology | Mice, Inbred C57BL | Cathepsin B - metabolism | Inflammation - immunology | Plasmodium chabaudi - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | CARD Signaling Adaptor Proteins | Malaria - parasitology | Proteomics | HSP90 Heat-Shock Proteins - metabolism | Hemeproteins - physiology | Mice | Phagocytosis | Hostages | Inflammation | Malaria | Phosphotransferases | Medical research | Salmonella | Phosphorylation | Lipids | Parasites | Experiments | Fever | Tropical diseases
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 05/2013, Volume 48, Issue 5, pp. 589 - 600
Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a deadly complication of malaria, and its pathophysiology is insufficiently understood.... 
Pulmonary inflammation | Plasmodium berghei NK65 | Malaria | Hemozoin | ARDS | ACTIVATION | FALCIPARUM | BIOCHEMISTRY & MOLECULAR BIOLOGY | pulmonary inflammation | MONOCYTES | INJURY | HAEMOZOIN | malaria | CELL BIOLOGY | PLASMODIUM-VIVAX MALARIA | ERYTHROCYTES | RESPIRATORY SYSTEM | PIGMENT HEMOZOIN | MICE | GROWTH-FACTOR | hemozoin | Pneumonia - parasitology | Tumor Necrosis Factor-alpha - metabolism | Plasmodium berghei - immunology | Species Specificity | Plasmodium berghei - physiology | Humans | Tumor Necrosis Factor-alpha - genetics | Vascular Endothelial Growth Factor A - metabolism | Respiratory Distress Syndrome, Adult - metabolism | Vascular Endothelial Growth Factor A - genetics | Respiratory Distress Syndrome, Adult - etiology | Macrophages - parasitology | Plasmodium chabaudi - immunology | Schizonts - immunology | Plasmodium chabaudi - physiology | Interleukin-10 - metabolism | Pneumonia - immunology | Chemokine CCL2 - metabolism | Lung - metabolism | Host-Parasite Interactions | Malaria - metabolism | Gene Expression | Hemeproteins - metabolism | Lung - parasitology | Schizonts - metabolism | Mice, Inbred C57BL | Organ Size | Chemokine CCL2 - genetics | CD4 Lymphocyte Count | Plasmodium chabaudi - metabolism | Macrophages - metabolism | Plasmodium berghei - metabolism | Animals | Interleukin-10 - genetics | Erythrocytes - metabolism | Malaria - parasitology | Hemeproteins - physiology | Malaria - complications | Mice | Bronchoalveolar Lavage Fluid - chemistry | Schizonts - physiology | Erythrocytes - parasitology | Pneumonia - metabolism | Lung - immunology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2005, Volume 280, Issue 9, pp. 8606 - 8616
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2009, Volume 183, Issue 8, pp. 5208 - 5220
The role of proinflammatory cytokine production in the pathogenesis of malaria is well established, but the identification of the parasite products that... 
TUMOR-NECROSIS-FACTOR | DENDRITIC CELLS | INTERFERON-GAMMA | TOLL-LIKE RECEPTOR-9 | PLASMODIUM-FALCIPARUM | EXPERIMENTAL CEREBRAL MALARIA | ENDOTHELIAL-CELLS | IMMUNOLOGY | NF-KAPPA-B | INNATE IMMUNE ACTIVATION | INTRACELLULAR COMPARTMENTS | Interleukin-1alpha - immunology | Chemokine CCL2 - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | NF-kappa B - metabolism | Inflammation - parasitology | Endothelial Cells - parasitology | Extracellular Signal-Regulated MAP Kinases - immunology | Plasmodium falciparum | Interleukin-1beta - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-8 - metabolism | Toll-Like Receptors - metabolism | Chemokine CXCL1 - metabolism | Interleukin-6 - metabolism | Carrier Proteins - immunology | Toll-Like Receptors - immunology | Chemokine CXCL1 - immunology | Signal Transduction - drug effects | Interleukin-6 - immunology | Malaria, Falciparum - immunology | Uric Acid - antagonists & inhibitors | Mice | Interleukin-8 - immunology | Inflammation - chemically induced | Tumor Necrosis Factor-alpha - metabolism | NF-kappa B - immunology | Interleukin-1alpha - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Hemeproteins - immunology | Macrophages - parasitology | Signal Transduction - immunology | Myeloid Differentiation Factor 88 - immunology | Cytoskeletal Proteins - metabolism | Chemokine CCL2 - metabolism | Macrophages - immunology | Uric Acid - metabolism | Interleukin-1beta - immunology | Hemeproteins - pharmacology | Inflammation - immunology | Endothelial Cells - immunology | Malaria, Falciparum - parasitology | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | CARD Signaling Adaptor Proteins | Allopurinol - pharmacology | Macrophages - drug effects | Myeloid Differentiation Factor 88 - metabolism | Interferon-gamma - pharmacology | Endothelial Cells - drug effects | Chemokine | TLR9 | Plasmodium | Inflammasome | NALP3 | Cytokine
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e90859
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2014, Volume 67, pp. 377 - 386
Red blood cells (RBCs) contain large amounts of iron and operate in highly oxygenated tissues. As a result, these cells encounter a continuous oxidative... 
Oxidative stress | Free radicals | Erythrocytes | Favism | Thalassemia | Methemoglobin | Pentose–phosphate pathway | Red blood cells | Hemolytic anemia | Sickle cell trait | Cytochrome b5 reductase | G6PD deficiency | Glutathione | Pentose-phosphate pathway | PLASMODIUM-FALCIPARUM MALARIA | NONSPHEROCYTIC HEMOLYTIC-ANEMIA | ENDOCRINOLOGY & METABOLISM | PENTOSE-PHOSPHATE SHUNT | LIPID-PEROXIDATION | OXIDATIVE STRESS PARAMETERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE-REDUCTASE DEFICIENCY | Cytochrome b reductase | 6-PHOSPHOGLUCONATE DEHYDROGENASE-DEFICIENCY | PYRIMIDINE 5'-NUCLEOTIDASE DEFICIENCY | PYRUVATE-KINASE DEFICIENCY | GLUCOSE-6-PHOSPHATE-DEHYDROGENASE DEFICIENCY | Erythropoiesis | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Oxidative Stress | Glutathione - metabolism | Anemia, Hemolytic - pathology | Antioxidants - metabolism | Humans | Sickle Cell Trait - metabolism | Glucosephosphate Dehydrogenase Deficiency - pathology | Thalassemia - pathology | Malaria - prevention & control | Erythrocytes - metabolism | Thalassemia - metabolism | Anemia, Hemolytic - metabolism | Erythrocytes - pathology | Glucosephosphate Dehydrogenase Deficiency - metabolism | NADP - metabolism | Sickle Cell Trait - pathology | Malaria - metabolism | Antioxidants | Phosphates | Glucose metabolism | Enzymes | Sickle cell anemia | Hemoglobin | Glucose | Dextrose
Journal Article
Blood, ISSN 0006-4971, 09/2007, Volume 110, Issue 6, pp. 2132 - 2139
Journal Article