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The Journal of biological chemistry, ISSN 0021-9258, 12/2010, Volume 285, Issue 49, pp. 37964 - 37975
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 10/2010, Volume 285, Issue 43, pp. 33054 - 33064
Journal Article
Nature (London), ISSN 0028-0836, 09/2016, Volume 538, Issue 7625, pp. 344 - 349
Antimalarial drugs have thus far been chiefly derived from two sources-natural products and synthetic drug-like compounds. Here we investigate whether... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Azabicyclo Compounds - pharmacology | Plasmodium falciparum - enzymology | Malaria, Falciparum - prevention & control | Male | Plasmodium falciparum - cytology | Azetidines - pharmacology | Plasmodium falciparum - drug effects | Cytosol - enzymology | Malaria, Falciparum - transmission | Liver - drug effects | Azabicyclo Compounds - chemical synthesis | Azabicyclo Compounds - therapeutic use | Female | Safety | Antimalarials - chemical synthesis | Disease Models, Animal | Life Cycle Stages - drug effects | Malaria, Falciparum - drug therapy | Azabicyclo Compounds - administration & dosage | Azetidines - adverse effects | Phenylurea Compounds - therapeutic use | Antimalarials - therapeutic use | Macaca mulatta - parasitology | Phenylalanine-tRNA Ligase - antagonists & inhibitors | Drug Discovery | Antimalarials - pharmacology | Animals | Azetidines - administration & dosage | Phenylurea Compounds - chemical synthesis | Antimalarials - administration & dosage | Azetidines - therapeutic use | Phenylurea Compounds - administration & dosage | Mice | Phenylurea Compounds - pharmacology | Liver - parasitology | Plasmodium falciparum - growth & development | Prevention | Antimalarials | Disease transmission | Health aspects | Transfer RNA | Proteins | Cytochrome | Malaria | Liver | Parasites | Kinases | Drug resistance | Drug dosages | Index Medicus
Journal Article
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 05/2010, Volume 328, Issue 5980, pp. 910 - 912
.... We have found that the plant-like calcium-dependent protein kinase PfCDPK5, which is expressed in invasive merozoite forms of Plasmodium falciparum, was critical for egress... 
Proteins | Medical research | Schizonts | REPORTS | Erythrocytes | Erythrocyte invasion | Antibodies | Ligands | Gene expression regulation | Parasites | Merozoites | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Plasmodium falciparum - enzymology | Protein Kinases - metabolism | Protein Kinases - genetics | Schizonts - enzymology | Humans | Protein Kinases - chemistry | Plasmodium falciparum - cytology | Protozoan Proteins - genetics | Cyclic GMP-Dependent Protein Kinases - metabolism | Recombinant Fusion Proteins - metabolism | Schizonts - cytology | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Protozoan Proteins - metabolism | Protozoan Proteins - chemistry | Host-Parasite Interactions | Plasmodium falciparum - physiology | Calcium-Binding Proteins - chemistry | Calcium-Binding Proteins - metabolism | Merozoites - physiology | Enzyme Inhibitors - pharmacology | Morpholines - metabolism | Merozoites - enzymology | Recombinant Fusion Proteins - chemistry | Pyrroles - pharmacology | Models, Biological | Pyridines - pharmacology | Plasmodium falciparum - growth & development | Schizonts - physiology | Erythrocytes - parasitology | Calcium-Binding Proteins - genetics | Physiological aspects | Plasmodium falciparum | Complications and side effects | Malaria | Health aspects | Biochemistry | Kinases | Protease | Replication | Egress | Index Medicus
Journal Article
Journal Article
Journal Article
Scientific reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, pp. 21802 - 21802
... and determines sexual stage commitment. Plasmodium falciparum encodes ten predicted SET domain-containing protein methyltransferases, six of which have been shown to be refractory to knock-out in blood stage parasites... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Plasmodium falciparum - enzymology | Baculoviridae - metabolism | Epigenesis, Genetic | Humans | Erythrocytes - ultrastructure | Substrate Specificity | Baculoviridae - genetics | Protozoan Proteins - genetics | Salivary Glands - parasitology | Spodoptera | Sf9 Cells | Sporozoites - enzymology | Protozoan Proteins - metabolism | Trophozoites - enzymology | Plasmodium falciparum - genetics | Cloning, Molecular | Trophozoites - ultrastructure | Plasmodium falciparum - ultrastructure | Recombinant Proteins - metabolism | Amino Acid Sequence | Gene Expression | Histone-Lysine N-Methyltransferase - genetics | Anopheles - parasitology | Recombinant Proteins - genetics | Sporozoites - ultrastructure | Sequence Homology, Amino Acid | Sequence Alignment | Animals | Histones - genetics | Histone-Lysine N-Methyltransferase - metabolism | Liver - cytology | Histones - metabolism | Kinetics | Liver - parasitology | Mutation | Erythrocytes - parasitology | Enzymes | Malaria | Gene families | Virulence | Liver | Salivary gland | Genomes | Parasites | Drug development | Nuclei | Proteins | Lysine | Antimalarial agents | Transcription activation | Sporozoites | DNA methylation | Histone methyltransferase | Nucleosomes | Acetylation | Localization | Cytoplasm | Histone H3 | Index Medicus | Life Sciences | Human health and pathology | Microbiology and Parasitology | Infectious diseases
Journal Article