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1. Phthalate esters
: toxicity and metabolism
by Woodward, Kevin N and Woodward, K. N
1988, ISBN 084936695X, 2 v.
Phthalic Acids | Toxicology | Phthalate esters | Metabolism | Toxicity
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2. Full Text Organophosphorus flame retardants and plasticizers: Sources, occurrence, toxicity and human exposure
by Wei, Gao-Ling and Li, Jun-Jie and Li, Ding-Qiang and Zhuo, Mu-Ning and Liao, Yi-Shan and Xie, Zhen-Yue and Guo, Tai-Long and Zhang, Si-Yi and Liang, Zhi-Quan
Environmental Pollution, ISSN 0269-7491, 01/2015, Volume 196, pp. 29 - 46
Due to the restricted use and ban of brominated flame retardants, organophosphorus compounds (OPs), extensively used as flame retardants and plasticizers, are... 
Emission sources | Toxicity | Organophosphorus flame retardants and plasticizers | Occurrence | Human exposure | INDOOR DUST | EMERGING POLLUTANTS | MICROWAVE-ASSISTED EXTRACTION | WASTE-WATER CONTAMINANTS | CHEMICAL-IONIZATION | POLYBROMINATED DIPHENYL ETHERS | ENVIRONMENTAL SCIENCES | GAS-CHROMATOGRAPHY | HOUSE-DUST | PHASE MICROEXTRACTION | ORGANIC CONTAMINANTS | Dust - analysis | Flame Retardants - analysis | Flame Retardants - toxicity | Humans | Halogenation | Environment | Organophosphorus Compounds - analysis | Organophosphorus Compounds - toxicity | Plasticizers - toxicity | Environmental Exposure - statistics & numerical data | Plasticizers - analysis | Fireproofing agents | Organophosphorus compounds | Phthalates | Index Medicus
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3. Full Text Priority and emerging flame retardants in rivers: Occurrence in water and sediment, Daphnia magna toxicity and risk assessment
by Cristale, Joyce and García Vázquez, Alejandro and Barata, Carlos and Lacorte, Silvia
Environment International, ISSN 0160-4120, 09/2013, Volume 59, pp. 232 - 243
The occurrence, partitioning and risk of eight polybrominated diphenyl ethers (PBDEs), nine new brominated (NBFRs) and ten organophosphorus flame retardants... 
D. magna toxicity | River | Organophosphate flame retardant | New brominated flame retardants | PBDE | Risk assessment | PHARMACEUTICALS | ENVIRONMENTAL OCCURRENCE | CHINA | MIXTURE TOXICITY | POLYBROMINATED DIPHENYL ETHERS | DECABROMODIPHENYL ETHANE | ENVIRONMENTAL SCIENCES | TREATMENT PLANTS | SURFACE WATERS | ORGANOPHOSPHATE ESTERS | PLASTICIZERS | Flame Retardants - analysis | Environmental Monitoring | Risk Assessment | Humans | Bromobenzenes - toxicity | Halogenated Diphenyl Ethers - analysis | Water Pollutants, Chemical - analysis | Bromobenzenes - analysis | Halogenated Diphenyl Ethers - toxicity | Daphnia - drug effects | Flame Retardants - toxicity | Animals | Water Pollutants, Chemical - toxicity | Rivers - chemistry | Geologic Sediments - chemistry | Biological Assay | Organophosphorus Compounds - analysis | Organophosphorus Compounds - toxicity | Water | Rivers | Fireproofing agents | Sediments (Geology) | Index Medicus | Partitioning | Toxicity | Flame retardants | Risk | Mathematical models | Ethers | Sediments
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4. Full Text Toxicity of Hexamoll® DINCH® following intravenous administration
by David, Raymond M and White, Randy D and Larson, Michael J and Herman, Jay K and Otter, Rainer
Toxicology Letters, ISSN 0378-4274, 10/2015, Volume 238, Issue 2, pp. 100 - 109
Alternative plasticizers to di(2-ethylhexyl) phthalate (DEHP) for blood bags have been sought for many years. Cyclohexane-1,2-dicarboxylic acid,... 
Cyclohexane-1,2-dicarboxylic acid, diisononylester (Hexamoll® DINCH®) | Intravenous injection | Intravenous infusion | IN-VITRO | ALTERNATIVE PLASTICIZER | RATS | TOXICOLOGY | GUIDE | Cyclohexane-1,2-dicarboxylic acid, diisononylester (Hexamoll (R) DINCH (R)) | EXPOSURE | BLOOD | CHLORIDE | FIBRIN | Dicarboxylic Acids - pharmacokinetics | Dicarboxylic Acids - toxicity | Biomarkers - urine | Injections, Intravenous | Risk Assessment | Cyclohexanecarboxylic Acids - administration & dosage | Biological Availability | Male | Biomarkers - blood | Plasticizers - toxicity | Rats, Sprague-Dawley | Dicarboxylic Acids - administration & dosage | Plasticizers - pharmacokinetics | No-Observed-Adverse-Effect Level | Plasticizers - administration & dosage | Animals | Biotransformation | Cyclohexanecarboxylic Acids - toxicity | Female | Cyclohexanecarboxylic Acids - pharmacokinetics | Infusions, Intravenous | Index Medicus
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5. Full Text Mixture toxicity of water contaminants-effect analysis using the zebrafish embryo assay (Danio rerio)
by Schmidt, Susanne and Busch, Wibke and Altenburger, Rolf and Küster, Eberhard
Chemosphere, ISSN 0045-6535, 06/2016, Volume 152, pp. 503 - 512
Three water contaminants were selected to be tested in the zebrafish embryo toxicity test (DarT) in order to investigate the sensitivity of the zebrafish... 
Baseline toxicity | FET | DNA damage | Micro pollutant | AQUATIC TOXICITY | AMINO-ALPHA-CARBOLINES | POLLUTANTS | MODEL | ENVIRONMENTAL SCIENCES | CARBENDAZIM | CHEMICALS | TOXICOLOGY | RISK-ASSESSMENT | DRINKING-WATER | EXPOSURE | Benzimidazoles - toxicity | Embryo, Nonmammalian - metabolism | Fungicides, Industrial - toxicity | Zebrafish | Dinitrobenzenes - toxicity | Plasticizers - toxicity | Embryo, Nonmammalian - drug effects | Pigments, Biological - metabolism | Animals | Drug Interactions | Water Pollutants, Chemical - toxicity | Biological Assay | Toxicity Tests | Carbamates - toxicity | Carbolines - toxicity | Embryonic development | Embryo | Analysis | Index Medicus
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6. Full Text Ecotoxic pharmaceuticals, personal care products, and other emerging contaminants: A review of environmental, receptor-mediated, developmental, and epigenetic toxicity with discussion of proposed toxicity to humans
by Wilkinson, John L and Hooda, Peter S and Barker, James and Barton, Stephen and Swinden, Julian
Critical Reviews in Environmental Science and Technology, ISSN 1064-3389, 02/2016, Volume 46, Issue 4, pp. 336 - 381
Pharmaceuticals and personal care products (PPCPs), other emerging contaminants (ECs), and metabolites thereof are ubiquitous in the environment, both built... 
non-monotonicity | epigenetic toxicity | pharmaceutical and personal care product (PPCP) | Emerging contaminant (EC) | environmental toxicology | prenatal toxicity | toxicity | nonmonotonicity | pharmaceutical and personal | care product (PPCP); prenatal | ENDOCRINE-DISRUPTING CHEMICALS | ZEBRAFISH DANIO-RERIO | ANTIBIOTIC-RESISTANCE | BREAST-MILK | ENVIRONMENTAL SCIENCES | IN-VITRO | WASTE-WATER | HUMAN URINE | TRANSGENERATIONAL INHERITANCE | BISPHENOL-A CONCENTRATIONS | PERFLUORINATED COMPOUNDS | Endocrine disruptors | Precipitation (meteorology) | Drugs | Musk | Toxicity | Food contamination | Personal grooming | Epidemiology | Ingestion | Analgesics | Metabolites | Trace levels | Urine | Plasticizers | Endocrine system | Consumer products | Chemical wastewater | Rainfall | Exposure | Sediments | Detergents | Biological activity | Heart rate | Perfluoro compounds | Organic chemistry | Fragrances | Reviews | Antibiotics | Contaminants | Epigenetics | Disruption | Cancer | Pharmaceuticals | Human | Biological
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7. Determination, toxicity, and environmental levels of phthalate plasticizers
by Zitko, V and Fisheries Research Board of Canada
1972, 344., Volume 344., 37
The production, properties, uses, toxicity, and determination of phthalates are reviewed. A cleanup of biological samples is described for the determination of... 
quantitative distribution | environmental pollution | marine pollution | plasticizers | toxicity tests | phthalate plasticizers | phthalates | toxicants
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8. Full Text Assessing effects of germline exposure to environmental toxicants by high-throughput screening in C. elegans
by Shin, Nara and Cuenca, Luciann and Karthikraj, Rajendiran and Kannan, Kurunthachalam and Colaiácovo, Monica P
PLoS Genetics, ISSN 1553-7390, 02/2019, Volume 15, Issue 2, pp. e1007975 - e1007975
Chemicals that are highly prevalent in our environment, such as phthalates and pesticides, have been linked to problems associated with reproductive health.... 
IN-VITRO | BISPHENOL-A EXPOSURE | CAENORHABDITIS-ELEGANS | INDUCED APOPTOSIS | URINARY CONCENTRATIONS | DNA-DAMAGE | GENETICS & HEREDITY | GENE-EXPRESSION | DOUBLE-STRAND BREAKS | PYRETHROID INSECTICIDES | PHTHALATE METABOLITES | Drug Evaluation, Preclinical - methods | Aneugens - toxicity | Permethrin - toxicity | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Germ Cells - drug effects | Thiocyanates - toxicity | Aneuploidy | Environmental Exposure | Plasticizers - toxicity | Caenorhabditis elegans - embryology | DNA Breaks, Double-Stranded | Meiosis - drug effects | Animals | Caenorhabditis elegans - drug effects | Benzothiazoles - toxicity | Dibutyl Phthalate - toxicity | Environmental Pollutants - toxicity | Insecticides - toxicity | High-Throughput Screening Assays - methods | Caenorhabditis elegans | Genetic engineering | Genetic aspects | High-throughput screening (Biochemical assaying) | Teratogenic agents | Analysis | In vitro fertilization | Reproductive health | Permethrin | Toxicity | p53 Protein | DNA damage | Benzothiazole | High-throughput screening | Lethality | Kinases | Oocytes | Embryogenesis | Toxicants | Metabolites | Deoxyribonucleic acid--DNA | Urine | Pesticides | Meiosis | Mammals | Gene expression | Double-strand break repair | Embryos | Chemicals | Bisphenol A | Nematodes | Wood preservatives | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
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9. Full Text Effects of six priority controlled phthalate esters with long-term low-dose integrated exposure on male reproductive toxicity in rats
by Gao, Hai-Tao and Xu, Qian and Xu, Run and Cao, Wei-Xin and Qian, Liang-Liang and Wang, Min and Lu, Lingeng and Yu, Shu-Qin
Food and Chemical Toxicology, ISSN 0278-6915, 03/2017, Volume 101, pp. 94 - 104
Human beings are inevitably exposed to ubiquitous phthalate esters (PEs) surroundings. The purposes of this study were to investigate the effects of long-term... 
Steroidogenesis | Phthalate esters | Reproductive toxicity | Long-term low-dose exposure | Cell cycle | Apoptosis | DIETHYLHEXYL PHTHALATE | MIXTURE | OXIDATIVE STRESS | IN-UTERO EXPOSURE | FOOD SCIENCE & TECHNOLOGY | TESTOSTERONE PRODUCTION | SPRAGUE-DAWLEY | DEHP | TESTIS | GENE-EXPRESSION | TOXICOLOGY | Luteinizing Hormone - analysis | Teratogens - toxicity | Phthalic Acids - toxicity | Humans | Cell Cycle Proteins - metabolism | Rats | Male | Plasticizers - toxicity | Esters - toxicity | Rats, Sprague-Dawley | Blotting, Western | Testis - drug effects | Reproduction - drug effects | Organ Size - drug effects | Animals | Apoptosis Regulatory Proteins | Testosterone - analysis | Diethylhexyl Phthalate - toxicity | Dibutyl Phthalate - toxicity | Insect Repellents - toxicity | Testosterone | Medical colleges | Pituitary hormones | Cytochrome P-450 | Cellulose | Luteinizing hormone | Chronic diseases | Esters | Dosage and administration | Glycoproteins | Tumor proteins | Epidemiology | Proteins | Index Medicus
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10. Full Text Toxicity of phthalate esters to lettuce (Lactuca sativa) and the soil microbial community under different soil conditions
by Ma, Tingting and Zhou, Wei and Chen, Like and Wu, Longhua and Christie, Peter and Liu, Wuxing
PLoS ONE, ISSN 1932-6203, 12/2018, Volume 13, Issue 12, pp. e0208111 - e0208111
Phthalate esters (PAEs) are globally used plasticizers and typical endocrine disruptors that can readily accumulate in agricultural products and represent a... 
BIODEGRADATION | SEED-GERMINATION | N-BUTYL PHTHALATE | MULTIDISCIPLINARY SCIENCES | GROWTH | PAES | VEGETABLES | PHYTOTOXICITY | RISK-ASSESSMENT | ACID ESTERS | WATER | Lettuce - chemistry | Lettuce - drug effects | Soil Microbiology | Food Safety | Microbiota - drug effects | Toxicity Tests, Subchronic | Plasticizers - toxicity | Vegetables - toxicity | Vegetables - chemistry | Crop Production | Soil - chemistry | Water - chemistry | Diethylhexyl Phthalate - toxicity | Dibutyl Phthalate - toxicity | Environmental Pollutants - toxicity | Hydrogen-Ion Concentration | Environmental aspects | Physiological aspects | Lettuce | Research | Soil microbiology | Phthalates | Butyl phthalate | Vegetables | Ascorbic acid | Soil sciences | Esters | Agricultural products | Biomass | pH effects | Leaf area | Soil pollution | Proteins | Microorganisms | Pollution | Soil testing | Food chains | Vitamin C | Food quality | Polymers | n-Butyl phthalate | Chlorophyll | Free radicals | Cell division | Metabolism | Organic chemistry | Soil microorganisms | Soil properties | Food safety | Photosynthesis | Endocrine disruptors | Microbial activity | Organic matter | Laboratories | Toxicity | Greenhouses | Soil investigations | Amino acids | Soil conditions | Soil environment | Biological effects | Carotenoids | Moisture content | Soils (organic) | pH | Chemical properties | Pollutants | Product safety | Sugar | Soil contamination | Soil chemistry | Biodegradation | Plasticizers | Soil moisture | Diversity indices | Health risks | Environmental impact | Soil pH | Phthalate esters | Soil organic matter | Environmental protection | Index Medicus
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11. Full Text Tris (1,3‐dichloro‐2‐propyl) phosphate induces toxicity by stimulating CaMK2 in PC12 cells
by Li, Chaonan and Li, Li and Lin, Bencheng and Fang, Yanjun and Yang, Honglian and Liu, Huanliang and Xi, Zhuge
Environmental Toxicology, ISSN 1520-4081, 06/2017, Volume 32, Issue 6, pp. 1784 - 1791
Tris (1,3‐dichloro‐2‐propyl) phosphate (TDCIPP) is one of the widely used organophosphorus flame retardants (OPFRs), which are regarded as suitable substitutes... 
toxicity | calmodulin dependent protein kinase | mitogen‐activated protein kinases | tris (1,3‐dichloro‐2‐propyl) phosphate | intracellular calcium ions | tris (1,3-dichloro-2-propyl) phosphate | mitogen-activated protein kinases | ORGANOPHOSPHORUS FLAME RETARDANTS | PATHWAYS | DEPENDENT PROTEIN-KINASE | WATER RESOURCES | TANDEM MASS-SPECTROMETRY | TDCPP | CHROMATOGRAPHY | ENVIRONMENTAL SCIENCES | HUMAN EXPOSURE | CALCIUM | TOXICOLOGY | TRIS(1,3-DICHLORO-2-PROPYL) PHOSPHATE | PLASTICIZERS | Cell Survival - drug effects | Phosphorylation | Rats | JNK Mitogen-Activated Protein Kinases - metabolism | Enzyme Activation - drug effects | PC12 Cells | Flame Retardants - toxicity | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Organophosphorus Compounds - toxicity | Protein-Serine-Threonine Kinases - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Phosphates | Fireproofing agents | Mitogens | Protein kinases | Calmodulin | Transcription factors | Toxicity | Bromination | Flame retardants | Cytotoxicity | Activation | Kinases | Proteins | Tubulin | Pathways | Calcium-binding protein | Retardants | Activation analysis | Fire retardant chemicals | Calcium (intracellular) | Extracellular signal-regulated kinase | c-Jun protein | MAP kinase | Extracellular | Cells | Protein kinase | Pheochromocytoma cells | Index Medicus
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12. Full Text Optical toxicity of triphenyl phosphate in zebrafish larvae
by Shi, Qipeng and Wang, Zongyi and Chen, Lianguo and Fu, Juanjuan and Han, Jian and Hu, Bing and Zhou, Bingsheng
Aquatic Toxicology, ISSN 0166-445X, 05/2019, Volume 210, pp. 139 - 147
Triphenyl phosphate (TPhP) has been shown to cause developmental neurotoxicty. Considering the visual system is a sensitive target, in the present study, we... 
Retina | Zebrafish | Opsin | Optical toxicity | Triphenyl phosphate | ORGANOPHOSPHORUS FLAME RETARDANTS | THYROID DISRUPTION | DEVELOPMENTAL NEUROTOXICITY | VISUAL-SYSTEM | ADULT | EARLY-LIFE STAGES | RESPONSES | MARINE & FRESHWATER BIOLOGY | ACUTE EXPOSURE | GENE-EXPRESSION | TOXICOLOGY | PLASTICIZERS | Retina - drug effects | Transcription, Genetic - drug effects | Phototaxis - drug effects | Retina - embryology | Vision, Ocular - drug effects | Embryo, Nonmammalian - drug effects | Dose-Response Relationship, Drug | Vision, Ocular - genetics | Animals | Water Pollutants, Chemical - toxicity | Larva | Organophosphates - toxicity | Retina - pathology | Phosphates | Gene expression | Analysis | Genes | Index Medicus
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