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Cancer Cell, ISSN 1535-6108, 08/2012, Volume 22, Issue 2, pp. 153 - 166
Genomic profiling has identified a subtype of high-risk B-progenitor acute lymphoblastic leukemia (B-ALL) with alteration of , a gene expression profile... 
GROWTH-FACTOR RECEPTOR | BCR-JAK2 FUSION GENE | ONCOLOGY | NUCLEAR-PORE | MYELOPROLIFERATIVE NEOPLASMS | ACUTE MYELOID-LEUKEMIA | OF-FUNCTION MUTATIONS | FLT3 MUTATIONS | CHILDHOOD | B-PROGENITOR | CHRONIC MYELOMONOCYTIC LEUKEMIA | CELL BIOLOGY | Recurrence | Humans | Molecular Sequence Data | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Protein-Tyrosine Kinases - genetics | DNA Mutational Analysis | Base Sequence | Trans-Activators - genetics | Phosphorylation - drug effects | Philadelphia Chromosome | Receptors, Cytokine - genetics | Genetic Predisposition to Disease | RNA, Messenger - genetics | Risk Factors | Gene Expression Regulation, Leukemic - drug effects | Signal Transduction - genetics | Enzyme Activation - drug effects | Mutation - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Signal Transduction - drug effects | Cell Transformation, Neoplastic | Oncogene Proteins, Fusion - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - enzymology | Mice | Protein Kinase Inhibitors - pharmacology | Gene Rearrangement - genetics | Sequence Deletion - genetics | Tyrosine | Platelet-derived growth factor | Cytokines | Genes | Oncology, Experimental | Genomes | Research | Gene expression | Population genetics | Hunger | Medical genetics | Genetic research | Nucleotide sequencing | Acute lymphocytic leukemia | Cancer | DNA sequencing | Index Medicus
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 10/2008, Volume 15, Issue 10, pp. 1109 - 1118
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2015, Volume 125, Issue 4, pp. 1419 - 1432
The small GTPase RAP1 is critical for platelet activation and thrombus formation. RAP1 activity in platelets is controlled by the GEF CalDAG-GEFI and an... 
GENE-MUTATIONS | MEDICINE, RESEARCH & EXPERIMENTAL | PROTEIN-KINASE-C | ADENOSINE-DIPHOSPHATE | ALPHA-IIB-BETA-3 ACTIVATION | MICE | CALDAG-GEFI | PLASMA-MEMBRANE | ADENYLATE-CYCLASE | ADP | MOUSE MODELS | Thrombopoiesis | Ticlopidine - pharmacology | rap1 GTP-Binding Proteins - antagonists & inhibitors | Platelet Activation - physiology | Thrombocytopenia - surgery | Splenectomy | Thrombocytopenia - genetics | Cellular Senescence | Hemostasis | Platelet Aggregation Inhibitors - pharmacology | GTPase-Activating Proteins - physiology | Guanine Nucleotide Exchange Factors - deficiency | Mice, Inbred C57BL | Receptors, Purinergic P2Y12 - physiology | Proto-Oncogene Proteins c-akt - physiology | Ticlopidine - analogs & derivatives | Mice, Knockout | Platelet Activation - genetics | Animals | rap1 GTP-Binding Proteins - physiology | Saphenous Vein - injuries | Clopidogrel | Mice | Mice, Inbred BALB C | Platelet Activation - drug effects | GTPase-Activating Proteins - genetics | Lymphopenia - genetics | Cell receptors | Development and progression | Cellular signal transduction | Genetic aspects | Properties | Health aspects | Blood platelet disorders | Heart attacks | Laboratories | Cloning | Thrombosis | Embryos | Proteins | Studies | Blood platelets | Rodents | Technological change | Protein expression | Mutation | Infrared imaging systems | Veins & arteries | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1424 - 1432
Anaphylaxis is an acute, severe, life-threatening multisystem allergic reaction resulting from the sudden systemic release of biochemical mediators and... 
Allergy and Immunology | Allergy | signaling | mediators | receptor antagonists | anaphylaxis | platelet-activating factor | mast cells | acetylhydrolase | platelets | sepsis | PHOSPHOLIPASE A INHIBITOR | CLINICAL-TRIAL | IMMUNOLOGY | FACTOR ACETYLHYDROLASE ACTIVITY | PHASE-II TRIAL | FACTOR PAF | FACTOR RECEPTOR ANTAGONIST | DOUBLE-BLIND | HUMAN NASAL AIRWAY | CORONARY-ARTERY-DISEASE | SEVERE SEPSIS | Blood Platelets - pathology | Blood Platelets - immunology | Humans | Platelet Activation - immunology | Platelet Activating Factor - immunology | Eosinophils - immunology | 1-Alkyl-2-acetylglycerophosphocholine Esterase - immunology | Receptors, G-Protein-Coupled - immunology | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Sepsis - pathology | Asthma - immunology | Anaphylaxis - immunology | Eosinophils - pathology | Platelet Aggregation - genetics | Neutrophils - pathology | Mast Cells - immunology | Platelet Membrane Glycoproteins - immunology | Sepsis - immunology | Platelet Aggregation - immunology | Signal Transduction | Anaphylaxis - pathology | Gene Expression Regulation | Neutrophils - immunology | Platelet Activating Factor - genetics | Platelet Membrane Glycoproteins - genetics | Asthma - genetics | Sepsis - genetics | Anaphylaxis - genetics | Platelet Activation - genetics | Mast Cells - pathology | Receptors, G-Protein-Coupled - genetics | Asthma - pathology | Enzymes | Immune response | Anaphylaxis | Permeability | Metabolites | Analysis | Proteins | Antigens | Blood platelets | E coli | Rodents | Preeclampsia | Lipids | Smooth muscle | Carbon | Biological activity | Index Medicus | Abridged Index Medicus
Journal Article
Blood, ISSN 0006-4971, 09/2016, Volume 128, Issue 9, pp. 1282 - 1289
Journal Article
Science Signaling, ISSN 1945-0877, 08/2013, Volume 6, Issue 287, pp. ra66 - ra66
Journal Article
Circulation Research, ISSN 0009-7330, 02/2013, Volume 112, Issue 4, pp. 595 - 600
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2018, Volume 24, Issue 2, pp. 232 - 238
Rhabdomyolysis is a serious syndrome caused by skeletal muscle injury and the subsequent release of breakdown products from damaged muscle cells into systemic... 
MEDICINE, RESEARCH & EXPERIMENTAL | CONTRIBUTE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAC-1 | MONOCYTES | ATHEROSCLEROSIS | NEUTROPHILS | CELL BIOLOGY | CD11B/CD18 | INFLAMMATION | RENAL-FAILURE | MICE | SICKLE-CELL-DISEASE | Heme - metabolism | Reactive Oxygen Species - metabolism | Extracellular Traps - metabolism | Extracellular Traps - genetics | Humans | Myoglobin - genetics | Rhabdomyolysis - complications | Crush Syndrome - etiology | Acute Kidney Injury - genetics | Muscle, Skeletal - injuries | Crush Syndrome - pathology | Secretory Vesicles - genetics | Rhabdomyolysis - pathology | Citrullination - genetics | Acute Kidney Injury - etiology | Disease Models, Animal | Macrophages - pathology | Acute Kidney Injury - pathology | Crush Syndrome - genetics | DNA - metabolism | DNA - genetics | Platelet Activation - genetics | Macrophages - metabolism | Animals | Rhabdomyolysis - genetics | Mice | Histones - metabolism | Muscle, Skeletal - pathology | Complications and side effects | Blood platelets | Physiological aspects | Development and progression | Genetic aspects | Research | Rhabdomyolysis | Macrophages | Acute renal failure | Myoglobin | Drug abuse | Reactive oxygen species | Renal function | Man made disasters | Seismic activity | Pathogenesis | Fibers | Proteins | Cell activation | Earthquakes | Rodents | Heme | Damage | Injuries | Deoxyribonucleic acid--DNA | Kidneys | Terrorism | Complications | Medical treatment | Muscles | Citrulline | Natural disasters | Skeletal muscle | Cellular biology | Hypoxia | Platelets | Index Medicus
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2011, Volume 187, Issue 1, pp. 391 - 400
Journal Article