X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (7021) 7021
Publication (745) 745
Book Review (554) 554
Book Chapter (31) 31
Conference Proceeding (14) 14
Dissertation (9) 9
Reference (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (6732) 6732
animals (4587) 4587
humans (4197) 4197
platelet-derived growth factor - metabolism (3277) 3277
mice (2331) 2331
male (1823) 1823
cells, cultured (1712) 1712
platelet-derived growth factor (1653) 1653
rats (1422) 1422
receptors, platelet-derived growth factor - metabolism (1390) 1390
cell biology (1339) 1339
signal transduction (1338) 1338
female (1326) 1326
biochemistry & molecular biology (1277) 1277
expression (1219) 1219
phosphorylation (1207) 1207
receptor, platelet-derived growth factor beta - metabolism (1120) 1120
receptor, platelet-derived growth factor alpha - metabolism (1056) 1056
platelet-derived growth factor - pharmacology (1049) 1049
oncology (836) 836
cell line (776) 776
proto-oncogene proteins c-sis (744) 744
platelet-derived growth factor - genetics (685) 685
immunohistochemistry (680) 680
growth-factor (678) 678
cell proliferation (651) 651
middle aged (646) 646
adult (622) 622
activation (617) 617
gene expression (613) 613
cells (612) 612
pdgf (579) 579
growth factors (550) 550
proliferation (539) 539
angiogenesis (537) 537
rna, messenger - metabolism (537) 537
rats, sprague-dawley (522) 522
receptor, platelet-derived growth factor alpha - genetics (512) 512
proteins (509) 509
time factors (497) 497
cancer (484) 484
cell proliferation - drug effects (482) 482
mice, inbred c57bl (477) 477
signal transduction - drug effects (476) 476
research (473) 473
cell line, tumor (467) 467
muscle, smooth, vascular - metabolism (461) 461
aged (457) 457
in-vivo (448) 448
blotting, western (444) 444
article (435) 435
disease models, animal (435) 435
molecular sequence data (434) 434
fibroblasts - metabolism (433) 433
vascular endothelial growth factor a - metabolism (413) 413
muscle, smooth, vascular - cytology (412) 412
analysis (411) 411
imatinib mesylate (411) 411
abridged index medicus (410) 410
fibroblasts (404) 404
mutation (404) 404
transforming growth factor beta - metabolism (391) 391
differentiation (389) 389
gene-expression (382) 382
in-vitro (380) 380
transfection (377) 377
receptor, platelet-derived growth factor beta - genetics (373) 373
multidisciplinary sciences (363) 363
signal transduction - physiology (363) 363
neurosciences (362) 362
3t3 cells (357) 357
receptor (354) 354
receptors (353) 353
pathology (350) 350
physiology (345) 345
apoptosis (340) 340
medicine, research & experimental (332) 332
cell differentiation (326) 326
physiological aspects (324) 324
cell division - drug effects (323) 323
medicine (319) 319
dose-response relationship, drug (317) 317
rna, messenger - genetics (317) 317
amino acid sequence (314) 314
research article (312) 312
hematology (309) 309
protein binding (304) 304
rodents (303) 303
inhibition (302) 302
receptors, platelet-derived growth factor - genetics (301) 301
stem cells (296) 296
cell movement (294) 294
vascular endothelial growth factor (293) 293
cell division (292) 292
fibrosis (291) 291
kinases (291) 291
growth (290) 290
enzyme activation (286) 286
growth-factor receptor (282) 282
muscle, smooth, vascular - drug effects (281) 281
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (6699) 6699
Chinese (217) 217
Japanese (61) 61
Polish (14) 14
Russian (10) 10
French (7) 7
German (7) 7
Spanish (4) 4
Hungarian (3) 3
Finnish (1) 1
Italian (1) 1
Korean (1) 1
Serbian (1) 1
Swedish (1) 1
Turkish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature, ISSN 0028-0836, 2014, Volume 508, Issue 1, pp. 118 - 122
Treatment of BRAF(V600E) mutant melanoma by small molecule drugs that target the BRAF or MEK kinases can be effective, but resistance develops invariably(1,2).... 
GROWTH-FACTOR RECEPTOR | BRAF INHIBITOR | RAF INHIBITION | CELLS | MULTIDISCIPLINARY SCIENCES | IMPROVED SURVIVAL | DIFFERENTIATION | C-JUN | CANCER | EXPRESSION | EGFR | Receptor, Epidermal Growth Factor - genetics | Humans | Receptor Protein-Tyrosine Kinases - biosynthesis | Cellular Senescence - drug effects | Melanoma - enzymology | Antineoplastic Agents - administration & dosage | Receptor, Platelet-Derived Growth Factor beta - genetics | Indoles - administration & dosage | Mitogen-Activated Protein Kinase Kinases - metabolism | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | SOXE Transcription Factors - deficiency | Proto-Oncogene Proteins B-raf - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Epidermal Growth Factor - biosynthesis | Gene Library | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Transforming Growth Factor beta - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Transforming Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor beta - biosynthesis | Sulfonamides - administration & dosage | Drug Resistance, Neoplasm - drug effects | SOXE Transcription Factors - genetics | Proteins | Biopsy | Rodents | Genes | Melanoma | Mutation | Kinases | Drug resistance | Patients | Tumors | Index Medicus
Journal Article
Journal Article
Cell, ISSN 0092-8674, 01/2018, Volume 172, Issue 3, pp. 534 - 548.e19
Journal Article
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 08/2014, Volume 26, Issue 2, pp. 288 - 300
Journal Article
Cancer Research, ISSN 0008-5472, 06/2008, Volume 68, Issue 12, pp. 4774 - 4782
Inhibition of tumor angiogenesis through blockade of the vascular endothelial growth factor (VEGF) signaling pathway is a novel treatment modality in oncology.... 
CELLS | POTENT | ONCOLOGY | CRYSTAL-STRUCTURE | VEGF | KINASE INHIBITORS | TYROSINE KINASES | TUMOR ANGIOGENESIS | SORAFENIB | CANCER | ENDOTHELIAL GROWTH-FACTOR | Endothelium, Vascular - cytology | Pericytes - drug effects | Apoptosis - drug effects | Humans | Pericytes - cytology | Rats, Inbred F344 | Indoles - chemical synthesis | Endothelium, Vascular - drug effects | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor Receptor-2 - immunology | Enzyme Inhibitors - chemical synthesis | Neoplasms, Experimental - pathology | Tissue Distribution | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Enzyme Inhibitors - pharmacokinetics | Female | Molecular Structure | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Signal Transduction | Pericytes - metabolism | Cells, Cultured | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Rats | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Enzyme Inhibitors - therapeutic use | Xenograft Model Antitumor Assays | Animals | Endothelium, Vascular - metabolism | Mice, Nude | Blood Coagulation Factors - antagonists & inhibitors | Receptors, Fibroblast Growth Factor - metabolism | Indoles - pharmacokinetics | Indoles - therapeutic use | Cell Proliferation - drug effects | Mice | Neoplasms, Experimental - metabolism | Neoplasms, Experimental - drug therapy | Index Medicus
Journal Article
Journal Article
Journal Article