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Advanced Drug Delivery Reviews, ISSN 0169-409X, 11/2013, Volume 65, Issue 13-14, pp. 1667 - 1685
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2012, Volume 109, Issue 30, pp. 11987 - 11992
Monofunctional platinum(II) complexes of general formula cis-[Pt(NH₃)₂(N-heterocycle)Cl]Cl bind DNA at a single site, inducing little distortion in the double... 
Cell culture techniques | HT29 cells | Reactivity | Platinum | DNA | Cell lines | Antineoplastics | Ligands | Kinetics | Adducts | X-ray crystallography | Metals in medicine | Cancer therapy | DNA damage | Transcription inhibition | cancer therapy | RESPONSES | COMPLEX | CISPLATIN | MULTIDISCIPLINARY SCIENCES | KINETIC CONTROL | metals in medicine | ADDUCTS | CIS-DIAMMINEDICHLOROPLATINUM(II) | transcription inhibition | Phenanthridines - chemistry | Crystallography, X-Ray | Drug Discovery - methods | Platinum Compounds - chemistry | Platinum Compounds - pharmacokinetics | Phenanthridines - pharmacology | Organoplatinum Compounds - pharmacology | Antineoplastic Agents - metabolism | Luciferases | Organoplatinum Compounds - metabolism | Organoplatinum Compounds - pharmacokinetics | Inhibitory Concentration 50 | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Deoxyguanine Nucleotides - metabolism | Molecular Structure | Gene Expression Regulation, Neoplastic - drug effects | Organoplatinum Compounds - chemistry | Phenanthridines - pharmacokinetics | Models, Molecular | DNA - metabolism | Antineoplastic Agents - chemistry | Genetic Vectors | Phenanthridines - metabolism | Platinum Compounds - pharmacology | Platinum Compounds - metabolism | Antimitotic agents | Composition | Platinum compounds | Physiological aspects | Genetic aspects | DNA binding proteins | Research | Antineoplastic agents | Health aspects | Pharmaceutical chemistry | Biological Sciences | Physical Sciences
Journal Article