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Science Translational Medicine, ISSN 1946-6234, 11/2014, Volume 6, Issue 261, pp. 261ra151 - 261ra151
Translating the recent success of chimeric antigen receptor (CAR) T cell therapy for hematological malignancies to solid tumors will necessitate overcoming... 
MEDICINE, RESEARCH & EXPERIMENTAL | LOCALIZATION | OVEREXPRESSION | CHIMERIC ANTIGEN RECEPTORS | ADENOCARCINOMAS | HIGH-AFFINITY | MONOCLONAL-ANTIBODY | ANTITUMOR-ACTIVITY | EXPRESSION | CANCER | LYMPHOCYTES | CELL BIOLOGY | Mesothelioma - immunology | Pleural Neoplasms - genetics | Cell Proliferation | Mesothelioma - pathology | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Receptors, Antigen, T-Cell - biosynthesis | CD4-Positive T-Lymphocytes - immunology | Pleural Neoplasms - metabolism | Time Factors | HEK293 Cells | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Receptors, Antigen, T-Cell - immunology | Cell Differentiation | Pleural Neoplasms - pathology | Lung Neoplasms - genetics | Immunotherapy, Adoptive - methods | Mesothelioma - therapy | Pleural Neoplasms - immunology | Transduction, Genetic | Lymphocyte Activation | CD4-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - transplantation | Lung Neoplasms - therapy | Mesothelioma - genetics | Mice, SCID | Pleural Neoplasms - therapy | GPI-Linked Proteins - metabolism | Xenograft Model Antitumor Assays | Lung Neoplasms - immunology | Animals | Mesothelioma - metabolism | CD4-Positive T-Lymphocytes - transplantation | Cell Line, Tumor | Mice, Inbred NOD | Receptors, Antigen, T-Cell - genetics | Chimerism | Cytotoxicity, Immunologic | Genetic Therapy - methods | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus
Journal Article
Pathology, ISSN 0031-3025, 02/2013, Volume 45, Issue 2, pp. 116 - 126
BAP1 (BRCA1-Associated Protein 1) was initially identified as a protein that binds to BRCA1. BAP1 is a tumour suppressor that is believed to mediate its... 
pathology | familial cancer | uveal melanoma | skin | diagnosis | inherited tumour susceptibility | melanoma | 3p21 loss syndrome | atypical Spitz tumour | germline mutation | BAP1 | Pathology | Inherited tumour susceptibility | Melanoma | Uveal melanoma | Atypical Spitz tumour | Familial cancer | Germline mutation | Skin | Diagnosis | PLEURAL MESOTHELIOMA | DNA-DAMAGE RESPONSE | BRCA1-ASSOCIATED PROTEIN-1 | RENAL-CELL CARCINOMA | BREAST-CANCER | POLYCOMB GROUP PROTEINS | SPITZ NEVI | HISTONE DEACETYLASE INHIBITORS | MALIGNANT MESOTHELIOMA | MYELODYSPLASTIC SYNDROMES | Neoplasms - metabolism | Carcinoma, Neuroendocrine - diagnosis | Melanoma - diagnosis | Humans | Lung Neoplasms - metabolism | Meningioma - genetics | Neoplasms - diagnosis | Paraganglioma - diagnosis | Adenocarcinoma - metabolism | Neoplasms - genetics | DNA Mutational Analysis | Melanoma - genetics | Gene Deletion | Nevus, Epithelioid and Spindle Cell - genetics | Skin Neoplasms - diagnosis | Tumor Suppressor Proteins - genetics | Biomarkers, Tumor - metabolism | Adenocarcinoma - genetics | Uveal Neoplasms - metabolism | Carcinoma, Neuroendocrine - metabolism | Lung Neoplasms - genetics | Melanoma - metabolism | Uveal Neoplasms - genetics | Genetic Predisposition to Disease | Meningioma - metabolism | Paraganglioma - genetics | Carcinoma, Neuroendocrine - genetics | Mesothelioma - diagnosis | Mesothelioma - genetics | Nevus, Epithelioid and Spindle Cell - metabolism | Ubiquitin Thiolesterase - genetics | Skin Neoplasms - metabolism | Immunohistochemistry - methods | Nevus, Epithelioid and Spindle Cell - diagnosis | Adenocarcinoma - diagnosis | Mesothelioma - metabolism | Paraganglioma - metabolism | Skin Neoplasms - genetics | Uveal Neoplasms - diagnosis | Biomarkers, Tumor - genetics | Meningioma - diagnosis | Mutation | Lung Neoplasms - diagnosis
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 4, pp. 407 - 416
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, pp. e0121071 - e0121071
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2006, Volume 12, Issue 19, pp. 5777 - 5785
Purpose: The DNA methylation paradox, manifested as derepression of cancer-testis antigens, and silencing of tumor suppressors during malignant transformation,... 
lung cancer | clinical trial | esophageal cancer | mesothelioma | epigenetics | 5-aza-2′-deoxycytidine | NY-ESO-1 | CELLS | HISTONE DEACETYLASE INHIBITOR | DNA METHYLATION | ONCOLOGY | IMMUNOTHERAPY | 5-AZA-2'-DEOXYCYTIDINE DECITABINE | ANTIGENS | TESTIS GENES | REFRACTORY SOLID TUMORS | PROMOTER | Lung Neoplasms - drug therapy | Genes, p16 - physiology | Pleural Neoplasms - genetics | DNA Modification Methylases - antagonists & inhibitors | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Transcriptional Activation | Male | Neoplasm Proteins - metabolism | Pleural Neoplasms - drug therapy | Pleural Neoplasms - metabolism | Esophageal Neoplasms - metabolism | Antigens, Neoplasm - metabolism | Adult | Antimetabolites, Antineoplastic - pharmacology | Female | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Proteins - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Azacitidine - analogs & derivatives | Mesothelioma - genetics | Mesothelioma - drug therapy | Azacitidine - pharmacology | Maximum Tolerated Dose | Carcinoma, Squamous Cell - drug therapy | Mesothelioma - metabolism | Esophageal Neoplasms - genetics | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Esophageal Neoplasms - drug therapy
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2011, Volume 17, Issue 14, pp. 4719 - 4730
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2015, Volume 125, Issue 6, pp. 2317 - 2334
Mast cells (MCs) have been identified in various tumors; however, the role of these cells in tumorigenesis remains controversial. Here, we quantified MCs in... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | C-KIT GENE | TUMOR PROGRESSION | INFLAMMATION | MOUSE MODEL | DEFICIENT | LUNG ADENOCARCINOMA | FACTOR-KAPPA-B | MICE | PROMOTES | Tryptases - metabolism | Colonic Neoplasms - genetics | Adenocarcinoma - pathology | Lung Neoplasms - diet therapy | Colonic Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Pleural Cavity - metabolism | Lung Neoplasms - pathology | Male | Interleukin-1beta - genetics | Pleural Effusion, Malignant - genetics | Proto-Oncogene Proteins c-kit - metabolism | Pleural Effusion, Malignant - pathology | Proto-Oncogene Proteins c-kit - antagonists & inhibitors | Colonic Neoplasms - metabolism | Pleural Effusion, Malignant - drug therapy | Adenocarcinoma - metabolism | Interleukin-1beta - metabolism | Mast Cells - metabolism | Proto-Oncogene Proteins c-kit - genetics | Adenocarcinoma - genetics | Benzamides - pharmacology | Tryptases - genetics | Lung Neoplasms - genetics | Pleural Effusion, Malignant - metabolism | Mice, Transgenic | Pyrimidines - pharmacology | Mice, SCID | Adenocarcinoma - drug therapy | Imatinib Mesylate | Piperazines - pharmacology | Animals | Colonic Neoplasms - pathology | Mast Cells - pathology | Cell Line, Tumor | Mice, Inbred NOD | Mice | Protein Kinase Inhibitors - pharmacology | Pleural Cavity - pathology | Studies | Flow cytometry | Rodents | Mortality | Melanoma | Cancer therapies | Tumors | Cancer | Angiogenesis | Oncology | Immunology | Cardiology | Vascular Biology
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