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plicamycin - analogs & derivatives (164) 164
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Clinical Cancer Research, ISSN 1078-0432, 08/2016, Volume 22, Issue 16, pp. 4105 - 4118
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, p. e35130
Deregulated activity of transcription factors (TFs) of the Sp/KLF family, like Sp1, Sp3 and Sp4, and consequent overexpression of Sp-regulated genes occur... 
COMBINATORIAL BIOSYNTHESIS | ANDROGEN RECEPTOR | PANCREATIC-CANCER | DRUG MITHRAMYCIN | BIOLOGY | ACCELERATES TUMOR-FORMATION | CELL-CYCLE PROGRESSION | TOLFENAMIC ACID | ANTITUMOR-ACTIVITY | PRODUCER STREPTOMYCES-ARGILLACEUS | ENDOTHELIAL GROWTH-FACTOR | Prostatic Neoplasms - metabolism | Antibiotics, Antineoplastic - pharmacology | Humans | Male | Prostate - metabolism | Prostate - pathology | Prostatic Neoplasms - genetics | Antibiotics, Antineoplastic - chemistry | Neoplasm Metastasis - drug therapy | Prostate - drug effects | Plicamycin - pharmacokinetics | Gene Expression Regulation, Neoplastic - drug effects | Antibiotics, Antineoplastic - pharmacokinetics | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - pathology | Plicamycin - therapeutic use | Sp Transcription Factors - metabolism | Plicamycin - pharmacology | Plicamycin - analogs & derivatives | Neoplasm Metastasis - genetics | Animals | Antibiotics, Antineoplastic - therapeutic use | Mice, Nude | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Sp Transcription Factors - genetics | Care and treatment | Genes | DNA binding proteins | Metastasis | Analysis | Genetically modified organisms | Genetic aspects | Genetic engineering | Nucleotide sequencing | Drug therapy | Prostate cancer | Protein binding | DNA sequencing | Cancer | Cell proliferation | Drugs | Cell culture | Animal models | Deregulation | Transcription factors | Toxicity | Oncology | Biosynthesis | Cancer therapies | Metastases | Ovarian cancer | Gene sequencing | Anticancer properties | Proteins | Angiogenesis | Xenografts | Inhibition | Deoxyribonucleic acid--DNA | Nucleotide sequence | Cultures | Pharmacology | Gene expression | Sp1 protein | Biological activity | Polymerase chain reaction | Overexpression | Pancreatic cancer | Antitumor activity | Plasma levels | Prostate | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e104687
Journal Article
Oncotarget, ISSN 1949-2553, 05/2016, Volume 7, Issue 21, pp. 30935 - 30950
Tumor initiating cells (TICs), responsible for tumor initiation, and cancer stem cells (CSCs), responsible for tumor expansion and propagation, are often... 
Myxoid liposarcoma | Mithralog EC-8042 | Cancer stem cells | DIG-MSK | Mesenchymal stem cells | COMBINATORIAL BIOSYNTHESIS | PROTEIN | mithralog EC-8042 | TRANSCRIPTION FACTOR SP1 | DOWN-REGULATION | ANTITUMOR-ACTIVITY | CANCER | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | IN-VITRO | THERAPY | mesenchymal stem cells | cancer stem cells | myxoid liposarcoma | EXPRESSION | Sarcoma, Experimental - metabolism | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Drug Resistance, Neoplasm | Sp1 Transcription Factor - metabolism | Antineoplastic Agents - therapeutic use | SOXB1 Transcription Factors - metabolism | ATP-Binding Cassette Transporters - metabolism | Female | Antineoplastic Agents - pharmacokinetics | Plicamycin - pharmacokinetics | Gene Expression Regulation, Neoplastic - drug effects | NF-kappa B p50 Subunit - metabolism | Plicamycin - therapeutic use | Receptor, Notch1 - metabolism | Mice, SCID | Proto-Oncogene Proteins c-myc - metabolism | Doxorubicin - pharmacokinetics | Plicamycin - analogs & derivatives | Sarcoma, Experimental - drug therapy | Xenograft Model Antitumor Assays | Sarcoma, Experimental - genetics | Animals | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Fluorescent Antibody Technique | Cell Line, Tumor | Mice, Inbred NOD | Cell Proliferation - drug effects
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 08/2014, Volume 219, pp. 123 - 132
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 1/2018, Volume 102, Issue 2, pp. 857 - 869
Journal Article