X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (12661) 12661
Book Chapter (134) 134
Dissertation (129) 129
Conference Proceeding (23) 23
Magazine Article (10) 10
Publication (4) 4
Book / eBook (2) 2
Book Review (2) 2
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
pluripotency (12071) 12071
stem cells (7991) 7991
animals (5293) 5293
humans (5178) 5178
differentiation (4538) 4538
cell biology (3989) 3989
mice (3729) 3729
gene expression (3480) 3480
cell differentiation (3458) 3458
expression (2579) 2579
embryonic stem cells (2559) 2559
multidisciplinary sciences (2338) 2338
self-renewal (2191) 2191
stem cell transplantation (2190) 2190
medicine (2031) 2031
proteins (1947) 1947
developmental biology (1909) 1909
cell & tissue engineering (1828) 1828
cell culture (1720) 1720
embryos (1700) 1700
embryo cells (1651) 1651
cells, cultured (1643) 1643
fibroblasts (1615) 1615
biochemistry & molecular biology (1608) 1608
science (1584) 1584
biology (1570) 1570
embryonic stem cells - cytology (1564) 1564
research (1477) 1477
research article (1477) 1477
genes (1448) 1448
transcription factors (1437) 1437
analysis (1427) 1427
cell line (1388) 1388
female (1380) 1380
embryonic stem cells - metabolism (1340) 1340
inhibitory postsynaptic potentials (1330) 1330
transplantation (1308) 1308
induced pluripotent stem cells (1295) 1295
embryonic stem-cells (1251) 1251
regeneration (1236) 1236
mouse (1227) 1227
pluripotent stem cells - cytology (1210) 1210
cell proliferation (1188) 1188
gene-expression (1173) 1173
generation (1140) 1140
biotechnology & applied microbiology (1137) 1137
male (1137) 1137
cancer (1129) 1129
embryonic structures (1126) 1126
induced pluripotent stem cells - cytology (1105) 1105
signal transduction (1101) 1101
transcription (1101) 1101
in-vitro (1097) 1097
genomes (1094) 1094
oncology (1045) 1045
induced pluripotent stem cells - metabolism (1030) 1030
stem-cells (994) 994
pluripotent stem cells - metabolism (990) 990
medicine, research & experimental (988) 988
dna methylation (959) 959
nanog (946) 946
oct-4 protein (924) 924
mutation (923) 923
apoptosis (898) 898
chromatin (880) 880
epigenetics (877) 877
genetic aspects (869) 869
deoxyribonucleic acid--dna (849) 849
pluripotent stem-cells (829) 829
neurons (826) 826
cardiomyocytes (813) 813
gene expression regulation, developmental (813) 813
activation (809) 809
kinases (803) 803
cell differentiation - genetics (802) 802
genetics & heredity (785) 785
cell cycle (771) 771
allografts (761) 761
induction (761) 761
hematology (756) 756
progenitor cells (756) 756
genetics (753) 753
mesenchyme (727) 727
gene (726) 726
life sciences (713) 713
physiological aspects (711) 711
proliferation (704) 704
cell differentiation - physiology (693) 693
transcription factors - metabolism (692) 692
rodents (689) 689
octamer transcription factor-3 - metabolism (671) 671
ribonucleic acid--rna (670) 670
methylation (651) 651
oct4 (651) 651
neural stem cells (646) 646
tissue engineering (638) 638
gene expression profiling (637) 637
es cells (629) 629
culture (613) 613
medical research (609) 609
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (12832) 12832
Japanese (72) 72
Chinese (36) 36
French (27) 27
German (20) 20
Portuguese (15) 15
Polish (13) 13
Korean (10) 10
Spanish (10) 10
Icelandic (2) 2
Slovenian (2) 2
Czech (1) 1
Persian (1) 1
Russian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Development (Cambridge), ISSN 1477-9129, 2017, Volume 144, Issue 7, pp. 1221 - 1234
Mouse embryonic stem (ES) cells are locked into self- renewal by shielding from inductive cues. Release from this ground state in minimal conditions offers a... 
Methylome | Rex1 | ES cells | Epiblast | Pluripotency | Transcriptome | DNA METHYLATION | NAIVE PLURIPOTENCY | TRANSCRIPTIONAL NETWORK | SELF-RENEWAL | DEVELOPMENTAL BIOLOGY | SPECIFICATION | GENOME | SUPER-ENHANCERS | EPIBLAST CELLS | PRIMED PLURIPOTENCY | GASTRULATING MOUSE EMBRYO | DNA methylation | Genomes | Extinction | Stem cells | 203 | Stem Cells and Regeneration
Journal Article
Development (Cambridge), ISSN 0950-1991, 01/2017, Volume 144, Issue 2, pp. 175 - 186
Journal Article
Cell Stem Cell, ISSN 1934-5909, 04/2016, Volume 18, Issue 4, pp. 481 - 494
The interconversion between naive and primed pluripotent states is accompanied by drastic epigenetic rearrangements. However, it is unclear whether intrinsic... 
methylation is sufficient to drive reprogramming to | are instead simply a reflection of discrete pluripotent | we show that blocking histone H3K4 | with more | findings show that discrete perturbation of H3K4 | it is unclear whether | determinant factors and EpiSC markers | indirectly regulate ESC transcription circuitry. These | naive embryonic stem cells (ESCs) within 3 days. Reverted | INDUCTION | naive pluripotency | The interconversion between naive and primed | competent chimeras | CELL BIOLOGY | generating germline | GROUND-STATE PLURIPOTENCY | ESCs reactivate the silenced X chromosome | PRIMED PLURIPOTENCY | pluripotent states is accompanied by drastic epigenetic | Importantly | H3K4 METHYLTRANSFERASE ACTIVITY | is highly efficient and synchronized | than 50% of treated EpiSCs exhibiting features of | which | of H3K4me1 at enhancers and represses lineage | and contribute to embryos following blastocyst injection | MOUSE EMBRYOS | inhibitor MM-401 reprograms mouse epiblast | to naive pluripotency or if distinct chromatin states | SELF-RENEWAL | states. Here | ACETYLTRANSFERASE MOF | CELL & TISSUE ENGINEERING | rearrangements. However | PRIMITIVE STREAK | CORE TRANSCRIPTIONAL NETWORK | methyltransferase MLL1 activity with the small | intrinsic epigenetic events can drive reprogramming | blocking MLL1 leads to global redistribution | X-CHROMOSOME INACTIVATION | molecule | stem cells (EpiSCs) to naive pluripotency. This reversion | Cell Line | Small Molecule Libraries - pharmacology | Germ Layers - drug effects | Myeloid-Lymphoid Leukemia Protein - metabolism | Myeloid-Lymphoid Leukemia Protein - deficiency | Histone-Lysine N-Methyltransferase - deficiency | Mouse Embryonic Stem Cells - drug effects | Mouse Embryonic Stem Cells - metabolism | Cellular Reprogramming - drug effects | Pluripotent Stem Cells - metabolism | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | Animals | Histone-Lysine N-Methyltransferase - metabolism | Pluripotent Stem Cells - drug effects | Mice | Oligopeptides - pharmacology | Myeloid-Lymphoid Leukemia Protein - antagonists & inhibitors
Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 12, p. e0210042
[This corrects the article DOI: 10.1371/journal.pone.0206844.]. 
Clustering | Regulators | Pluripotency
Journal Article
Cell Reports, ISSN 2211-1247, 07/2018, Volume 24, Issue 2, pp. 489 - 502
The genetic basis of naive pluripotency maintenance and loss is a central question in embryonic stem cell biology. Here, we deploy CRISPR-knockout-based... 
CRISPR | screening | exit from pluripotency | GATOR1 | Nprl2 | Tsc2 | Akt | naive pluripotency | mTORC2 | mTORC1 | GAP ACTIVITY | TRANSITION | TARGET | COMPLEX | GROUND-STATE PLURIPOTENCY | EMBRYONIC STEM-CELLS | GENETIC SCREENS | SELF-RENEWAL | DIFFERENTIATION | MTORC1 PATHWAY | CELL BIOLOGY
Journal Article