X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (9192) 9192
Book Review (2647) 2647
Publication (1527) 1527
Book Chapter (195) 195
Conference Proceeding (39) 39
Dissertation (10) 10
Magazine Article (8) 8
Book / eBook (6) 6
Reference (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (7814) 7814
humans (6227) 6227
animals (4455) 4455
stem cells (4303) 4303
cell biology (2785) 2785
pluripotent stem-cells (2720) 2720
differentiation (2536) 2536
mice (2500) 2500
cell differentiation (2239) 2239
induced pluripotent stem cells - cytology (2014) 2014
induced pluripotent stem cells (1782) 1782
cells, cultured (1676) 1676
pluripotent stem cells - cytology (1658) 1658
induced pluripotent stem cells - metabolism (1601) 1601
pluripotency (1591) 1591
cell & tissue engineering (1554) 1554
article (1548) 1548
embryonic stem cells (1421) 1421
analysis (1344) 1344
gene expression (1290) 1290
cell line (1255) 1255
in-vitro (1240) 1240
expression (1233) 1233
generation (1215) 1215
transplantation (1193) 1193
cell differentiation - drug effects (1180) 1180
research (1162) 1162
pluripotent stem cells - metabolism (1117) 1117
biotechnology & applied microbiology (1092) 1092
medicine (1059) 1059
multidisciplinary sciences (1012) 1012
medicine, research & experimental (1002) 1002
embryonic stem cells - cytology (987) 987
biochemistry & molecular biology (955) 955
fibroblasts (941) 941
biology (920) 920
induced pluripotent stem cells - drug effects (895) 895
male (822) 822
developmental biology (813) 813
neurons (802) 802
female (796) 796
pluripotent stem cells - drug effects (789) 789
induction (771) 771
mouse (771) 771
pluripotent stem cells (746) 746
self-renewal (723) 723
neurosciences (710) 710
stem cell transplantation (684) 684
cell culture (683) 683
proteins (681) 681
embryonic stem cells - metabolism (673) 673
cardiomyocytes (671) 671
regeneration (635) 635
tissue engineering (631) 631
physiological aspects (611) 611
hematology (603) 603
cell differentiation - physiology (588) 588
genes (583) 583
mutation (576) 576
research article (571) 571
gene-expression (565) 565
human fibroblasts (558) 558
oncology (557) 557
progenitor cells (557) 557
pharmacology & pharmacy (552) 552
cell differentiation - genetics (548) 548
disease (543) 543
genetic aspects (539) 539
cancer (531) 531
induced pluripotent stem cells - physiology (526) 526
science (522) 522
models, biological (509) 509
review (507) 507
fibroblasts - cytology (505) 505
stem cell research (503) 503
cell proliferation (502) 502
embryos (501) 501
genetics (497) 497
health aspects (497) 497
stem-cells (493) 493
regenerative medicine (491) 491
signal transduction (481) 481
myocytes, cardiac - cytology (480) 480
medical research (477) 477
cell culture techniques (474) 474
life sciences (470) 470
cell culture techniques - methods (464) 464
cellular reprogramming (462) 462
drug discovery (458) 458
phenotype (456) 456
pluripotent stem cells - physiology (452) 452
embryonic stem-cells (449) 449
neurons - cytology (448) 448
culture (447) 447
transcription factors (447) 447
heart (443) 443
embryonic stem cells - drug effects (431) 431
models (425) 425
myocytes, cardiac - metabolism (420) 420
ips cells (418) 418
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (9220) 9220
Japanese (21) 21
French (9) 9
Chinese (7) 7
German (3) 3
Russian (3) 3
Spanish (3) 3
Korean (2) 2
Portuguese (2) 2
Italian (1) 1
Polish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2015, Volume 112, Issue 40, pp. 12516 - 12521
Human pluripotent stem cell-based in vitro models that reflect human physiology have the potential to reduce the number of drug failures in clinical trials and... 
Organoid | Toxicology | Differentiation | Tissue engineering | Machine learning | toxicology | HUMAN NEOCORTEX | tissue engineering | DEVELOPMENTAL NEUROTOXICITY | differentiation | HUMAN BRAIN | MULTIDISCIPLINARY SCIENCES | CLASSIFICATION | FATTY-ACIDS | machine learning | CANCER | organoid | IN-VITRO | HUMAN CEREBRAL-CORTEX | MICROGLIA | GENE-EXPRESSION | Embryonic Stem Cells - metabolism | Microglia - metabolism | Embryonic Stem Cells - cytology | Humans | Brain - growth & development | Support Vector Machine | Neural Stem Cells - cytology | Xenobiotics - pharmacology | Brain - metabolism | Neurogenesis - genetics | Mesenchymal Stromal Cells - cytology | Xenobiotics - classification | Gene Expression Regulation, Developmental | Cell Differentiation | Neurogenesis - drug effects | Culture Media, Serum-Free - pharmacology | Gene Ontology | Polyethylene Glycols - pharmacology | Microglia - cytology | Mesenchymal Stromal Cells - drug effects | Brain - cytology | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Microglia - drug effects | Endothelial Cells - metabolism | Cells, Cultured | Neural Stem Cells - drug effects | Mesenchymal Stromal Cells - metabolism | Cell Communication - genetics | Macrophages - cytology | Pluripotent Stem Cells - metabolism | Macrophages - metabolism | Embryonic Stem Cells - drug effects | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Cell Communication - drug effects | Macrophages - drug effects | Hydrogels - pharmacology | Neural Stem Cells - metabolism | Endothelial Cells - drug effects | Neurotoxicity | Stem cells | Gene expression | Biological assays | Bioinformatics | Artificial intelligence | Index Medicus | Biological Sciences
Journal Article
Nature, ISSN 0028-0836, 02/2011, Volume 470, Issue 7332, pp. 105 - 110
Studies in embryonic development have guided successful efforts to direct the differentiation of human embryonic and induced pluripotent stem cells (PSCs) into... 
VIVO | NEUROGENIN-3 | MULTIDISCIPLINARY SCIENCES | BETA-CELLS | ENDODERM | DEFINED CONDITIONS | GENERATION | SPECIFICATION | FATE | EFFICIENT DIFFERENTIATION | ENDOCRINE-CELLS | Body Patterning - drug effects | Intestines - drug effects | Wnt Proteins - pharmacology | Embryonic Stem Cells - cytology | Humans | Endoderm - embryology | Intestines - embryology | Organogenesis - drug effects | Intestines - anatomy & histology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Time Factors | Endoderm - cytology | Fibroblast Growth Factor 4 - pharmacology | Cell Culture Techniques | Culture Media - chemistry | Induced Pluripotent Stem Cells - cytology | Basic Helix-Loop-Helix Transcription Factors - genetics | Induced Pluripotent Stem Cells - drug effects | Cells, Cultured | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Microvilli - drug effects | Activins - pharmacology | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Endoderm - drug effects | Culture Media - pharmacology | Morphogenesis - drug effects | Wnt3 Protein | Wnt3A Protein | Intestines - cytology | Physiological aspects | Intestines | Genetic aspects | Health aspects | Endoderm | Stem cells | Proteins | Studies | Index Medicus | posterior endoderm | intestine | FGF | transplantation | colon | drug transport | Wnt | progenitor cell
Journal Article
Nature, ISSN 0028-0836, 05/2008, Volume 453, Issue 7194, pp. 519 - 523
In the three decades since pluripotent mouse embryonic stem (ES) cells were first described they have been derived and maintained by using various empirical... 
MAINTENANCE | ACTIVATION | COMMITMENT | MECHANISM | TERATOCARCINOMA | MULTIDISCIPLINARY SCIENCES | PLURIPOTENCY | MOUSE ES CELLS | DIFFERENTIATION | EXPRESSION | PROTEIN-KINASE INHIBITORS | Embryonic Stem Cells - metabolism | Diphenylamine - pharmacology | Embryonic Stem Cells - cytology | Diphenylamine - analogs & derivatives | STAT3 Transcription Factor - deficiency | Benzamides - pharmacology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Cell Survival - drug effects | Pluripotent Stem Cells - cytology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Cells, Cultured | Pyrimidines - pharmacology | Glycogen Synthase Kinase 3 - metabolism | Regeneration - physiology | Pluripotent Stem Cells - metabolism | Regeneration - drug effects | Animals | MAP Kinase Signaling System - drug effects | Embryonic Stem Cells - drug effects | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cell Differentiation - drug effects | Pluripotent Stem Cells - drug effects | Cell Proliferation - drug effects | Mice | Pyridines - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Morphogenesis | Cytokines | Influence | Regeneration (Biology) | Research | Genetic transcription | Embryonic stem cells | Properties | Protein kinases | Proteins | Signal transduction | Cyclin-dependent kinases | Stem cells | Cell cycle | Kinases | Apoptosis | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 10/2012, Volume 111, Issue 9, pp. 1125 - 1136
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2015, Volume 17, Issue 8, pp. 994 - 1003
The use of human pluripotent stem cells for in vitro disease modelling and clinical applications requires protocols that convert these cells into relevant... 
DIRECTED DIFFERENTIATION | IN-VIVO | MOUSE | DEFINITIVE ENDODERM | GROWTH-FACTOR | HUMAN BLASTOCYSTS | STROMAL CELLS | WNT | CULTURE | LINES | CELL BIOLOGY | Coculture Techniques | Humans | Endothelial Cells - transplantation | Glycogen Synthase Kinase 3 beta | Cell Lineage - drug effects | Dose-Response Relationship, Drug | Human Umbilical Vein Endothelial Cells - physiology | Transfection | Time Factors | Gene Expression Regulation, Developmental | Transcription, Genetic | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-sis - pharmacology | Myocytes, Smooth Muscle - transplantation | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - physiology | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Biomarkers - metabolism | Cell Line | Induced Pluripotent Stem Cells - enzymology | Induced Pluripotent Stem Cells - drug effects | Induced Pluripotent Stem Cells - physiology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Myocytes, Smooth Muscle - enzymology | Induced Pluripotent Stem Cells - transplantation | Myocytes, Smooth Muscle - physiology | Gene Expression Profiling - methods | Muscle, Smooth, Vascular - transplantation | Glycogen Synthase Kinase 3 - metabolism | Mice, SCID | Muscle, Smooth, Vascular - cytology | Metabolomics - methods | Bone Morphogenetic Protein 4 - pharmacology | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Cell Differentiation - drug effects | Mice, Inbred NOD | Protein Kinase Inhibitors - pharmacology | Endothelial Cells - enzymology | Muscle, Smooth, Vascular - enzymology | Neovascularization, Physiologic | Endothelial Cells - drug effects | Usage | Cell research | Growth | Stem cells | Muscle cells | Research | Cell differentiation | Endothelium | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, pp. e18293 - e18293
Background: The production of cardiomyocytes from human induced pluripotent stem cells (hiPSC) holds great promise for patient-specific cardiotoxicity drug... 
DEFINED MEDIUM | MESODERM | MULTIDISCIPLINARY SCIENCES | ENDODERM | CARDIOMYOCYTE DIFFERENTIATION | INDUCTION | LINES | FUNCTIONAL-PROPERTIES | Body Patterning - drug effects | Oxygen - pharmacology | Antigens, CD34 - metabolism | Polyvinyl Alcohol - pharmacology | Humans | Fibroblast Growth Factor 2 - pharmacology | Mesoderm - drug effects | Mesoderm - cytology | Cell Culture Techniques - methods | Embryoid Bodies - metabolism | Embryoid Bodies - cytology | Adult | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Cell Line | Insulin - pharmacology | Induced Pluripotent Stem Cells - drug effects | Myocytes, Cardiac - cytology | Transgenes - genetics | Fetal Blood - cytology | Cell Adhesion - drug effects | Bone Morphogenetic Protein 4 - pharmacology | Genetic Vectors - genetics | Embryoid Bodies - drug effects | Animals | Myocytes, Cardiac - drug effects | Cell Differentiation - drug effects | Fibroblasts - drug effects | Culture Media - pharmacology | Myocytes, Cardiac - metabolism | Cell Proliferation - drug effects | Fibroblasts - cytology | Mice | Electrophysiological Phenomena - drug effects | Physiological aspects | Bone morphogenetic proteins | Fibroblast growth factors | Embryonic stem cells | Analysis | Drugs | Neonates | Neuropathology | Variability | Embryo cells | Alcohol | Drug development | Blood | Contraction | Regeneration (physiology) | Engineering | Cord blood | Efficiency | Calcium-binding protein | Fibroblasts | Long QT syndrome | Modelling | Polyvinyl alcohol | Heart diseases | Biomedical engineering | Fibroblast growth factor 2 | CD34 antigen | Bone morphogenetic protein 4 | Anemia | Cardiomyocytes | Insulin | Embryos | Coronary artery disease | Medicine | Regeneration | Troponin | Troponin I | Plasmids | Stem cells | Epigenetics | Mutation | Differentiation | Pluripotency | Index Medicus | Coronary heart disease
Journal Article
Nature, ISSN 0028-0836, 06/2015, Volume 522, Issue 7555, pp. 216 - 220
Multiple sclerosis involves an aberrant autoimmune response and progressive failure of remyelination in the central nervous system. Prevention of neural... 
MYELIN BASIC-PROTEIN | TRANSCRIPTS | GLUCOCORTICOIDS | MULTIPLE-SCLEROSIS | LYSOLECITHIN | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | SPINAL-CORD | CENTRAL-NERVOUS-SYSTEM | DIFFERENTIATION | OLIGODENDROCYTE PROGENITOR CELLS | Oligodendroglia - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Cerebellum - drug effects | Myelin Sheath - drug effects | Male | Receptors, Glucocorticoid - metabolism | Demyelinating Diseases - metabolism | MAP Kinase Signaling System | Myelin Sheath - metabolism | Oligodendroglia - drug effects | Female | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Demyelinating Diseases - drug therapy | Disease Models, Animal | Multiple Sclerosis - metabolism | Germ Layers - drug effects | Germ Layers - pathology | Encephalomyelitis, Autoimmune, Experimental - pathology | Lysophosphatidylcholines | Pluripotent Stem Cells - cytology | Germ Layers - metabolism | Tissue Culture Techniques | Cerebellum - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Cerebellum - pathology | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Animals | Cell Differentiation - drug effects | Miconazole - pharmacology | Pluripotent Stem Cells - drug effects | Multiple Sclerosis - pathology | Mice | Clobetasol - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Multiple Sclerosis - drug therapy | Medical research | Myelination | Multiple sclerosis | Stem cells | Physiological aspects | Medicine, Experimental | Research | Drugs | Proteins | Blood-brain barrier | Laboratories | Rodents | Clinical trials | FDA approval | Gene expression | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 3, pp. E291 - E299
Protein transduction domains (PTDs) are powerful nongenetic tools that allow intracellular delivery of conjugated cargoes to modify cell behavior. Their use in... 
Human embryonic stem cells | Transduction | Cell-penetrating peptides | Differentiation | Heparin-binding domain | differentiation | transduction | MULTIDISCIPLINARY SCIENCES | MECHANISMS | HEPARIN | MAMMALIAN-CELLS | IPS CELLS | PLURIPOTENT STEM-CELLS | cell-penetrating peptides | heparin-binding domain | MACROPIN