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Nature Medicine, ISSN 1078-8956, 11/2016, Volume 22, Issue 11, pp. 1277 - 1284
Bacterial infection is highly prevalent in patients who have had a stroke. Despite the potential contribution of micro-aspiration in post-stroke pneumonia, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | VENTILATOR-ASSOCIATED PNEUMONIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROBIOTA | CELL BIOLOGY | STROKE | ASPIRATION PNEUMONIA | TRAUMATIC BRAIN-INJURY | RESISTANCE | CENTRAL-NERVOUS-SYSTEM | STAPHYLOCOCCUS-AUREUS | COMPLICATIONS | DYSFUNCTION | Enterococcus faecalis | Bacteremia - immunology | Gram-Positive Bacterial Infections - immunology | Humans | Middle Aged | Male | Infarction, Middle Cerebral Artery - immunology | Pneumonia, Bacterial - metabolism | Gram-Positive Bacterial Infections - metabolism | Bacteremia - microbiology | Adrenergic beta-Antagonists - pharmacology | Urinary Tract Infections - metabolism | Bacterial Infections - immunology | Gram-Positive Bacterial Infections - microbiology | Aged, 80 and over | Female | Urinary Tract Infections - microbiology | Zonula Occludens-1 Protein - metabolism | Receptors, Adrenergic, beta - metabolism | Bacterial Infections - microbiology | Stroke - immunology | Disease Models, Animal | Permeability - drug effects | Pneumonia, Bacterial - microbiology | Specific Pathogen-Free Organisms | Blood Culture | Intestine, Small - microbiology | Computational Biology | Bacterial Translocation - immunology | Gastrointestinal Microbiome - genetics | Goblet Cells - metabolism | Bacteremia - metabolism | Animals | Sequence Analysis, RNA | Intestine, Small - cytology | Microbiota - genetics | Intestine, Small - drug effects | RNA, Ribosomal, 16S - genetics | Pneumonia, Bacterial - immunology | Aged | High-Throughput Nucleotide Sequencing | Mice | Intestine, Small - metabolism | Urinary Tract Infections - immunology | Bacterial Infections - metabolism | Goblet Cells - cytology | Stroke (Disease) | Ribosomal RNA | Bacteria, Pathogenic | Physiological aspects | Genetic aspects | Virulence (Microbiology) | Identification and classification | Stroke | Pneumonia | Bacterial infections
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2007, Volume 98, Issue 3, pp. 512 - 520
The plasminogen activation system is part of the fibrinolysis which is tightly regulated and protected against dysfunction by various activators and... 
Theme Issue Article | Bacterial infection | Inflammation | Plasminogen | Plasminogen activator inhibitor | Urokinase/receptor | BORRELIA-BURGDORFERI | ALPHA-ENOLASE | OUTER SURFACE PROTEIN | BINDING-PROTEIN | bacterial infection | BLOOD MONONUCLEAR-CELLS | plasminogen | GROUP-A STREPTOCOCCI | inflammation | YERSINIA-PESTIS | urokinase/receptor | UROKINASE RECEPTOR | PERIPHERAL VASCULAR DISEASE | plasminogen activator inhibitor | HEMATOLOGY | HELICOBACTER-PYLORI | PESTIS PLASMINOGEN-ACTIVATOR | Borrelia Infections - blood | Bacterial Infections - enzymology | Tissue Plasminogen Activator - metabolism | Humans | Plasminogen Activators - metabolism | Metalloendopeptidases - metabolism | Plasminogen - metabolism | Meningitis, Bacterial - blood | Receptors, Urokinase Plasminogen Activator | Borrelia Infections - microbiology | Plasminogen Activator Inhibitor 1 - metabolism | Bacterial Infections - microbiology | Disease Models, Animal | Pneumonia, Bacterial - blood | Bacteria - metabolism | Meningitis, Bacterial - microbiology | Pneumonia, Bacterial - microbiology | Meningitis, Bacterial - enzymology | Signal Transduction | Pneumonia, Bacterial - enzymology | Receptors, Cell Surface - metabolism | Fibrinolysis | Animals | Carrier Proteins - metabolism | Helicobacter pylori - metabolism | Urokinase-Type Plasminogen Activator - metabolism | Sepsis - enzymology | Bacteria - enzymology | Bacterial Proteins - metabolism | Bacteria - pathogenicity | Mice | Sepsis - blood | Bacterial Infections - blood | Borrelia Infections - enzymology | Sepsis - microbiology | Streptokinase - metabolism
Journal Article
PLoS Pathogens, ISSN 1553-7366, 11/2011, Volume 7, Issue 11, p. e1002357
Transition row metal ions are both essential and toxic to microorganisms. Zinc in excess has significant toxicity to bacteria, and host release of Zn(II) at... 
TRANSPORT PROTEIN ZNUA | PSAA MUTANTS | CRYSTAL-STRUCTURE | ESCHERICHIA-COLI | MICROBIOLOGY | BINDING PROTEIN | STREPTOCOCCUS-PNEUMONIAE | VIROLOGY | DOUBLE-BLIND | HYDROGEN-PEROXIDE | METAL-IONS | YOUNG-CHILDREN | PARASITOLOGY | Pneumococcal Infections - metabolism | Oxidative Stress | Adhesins, Bacterial - chemistry | Lipoproteins - genetics | Zinc - metabolism | Adhesins, Bacterial - genetics | Bacterial Proteins - chemistry | Zinc - chemistry | Adhesins, Bacterial - metabolism | Pneumococcal Infections - immunology | Streptococcus pneumoniae - metabolism | Lipoproteins - metabolism | Ion Transport - drug effects | Pneumococcal Infections - microbiology | Bacterial Adhesion - drug effects | Streptococcus pneumoniae - physiology | Binding, Competitive | Streptococcus pneumoniae - drug effects | Neutrophils - immunology | Lipoproteins - chemistry | Manganese - chemistry | Immunity, Innate | Mucous Membrane - metabolism | Animals | Manganese - metabolism | Protein Binding | Bacterial Proteins - metabolism | Mice | Zinc - pharmacology | Pneumonia | Bacterial pneumonia | Physiological aspects | Zinc in the body | Bacteria | Research | Health aspects | Risk factors | Protein binding | Competition | Oxidative stress | Bacterial infections | Toxicity | Ear diseases | Experiments | Zinc | Developing countries--LDCs | Stress | Streptococcus infections | Proteins | Ratios | Binding sites | Immune system | Developing countries | LDCs
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2014, Volume 143, Issue 2, pp. 225 - 245
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2011, Volume 7, Issue 8, p. e1002192
A significant number of environmental microorganisms can cause serious, even fatal, acute and chronic infections in humans. The severity and outcome of each... 
SYSTEM | DROSOPHILA-MELANOGASTER | MICROBIOLOGY | BACTERIAL | HOMOSERINE LACTONES | PATHOGENICITY | VIROLOGY | BURKHOLDERIA-PSEUDOMALLEI | GENETIC ADAPTATION | PSEUDOMONAS QUINOLONE SIGNAL | CYSTIC-FIBROSIS PATIENTS | AERUGINOSA ENCODES | PARASITOLOGY | Acute Disease | Quorum Sensing - physiology | Humans | Bacterial Proteins - genetics | Pneumonia, Bacterial - metabolism | Gene Expression Regulation, Bacterial - physiology | Pseudomonas Infections - genetics | Pseudomonas Infections - metabolism | Animals | Pseudomonas aeruginosa - genetics | Pseudomonas aeruginosa - pathogenicity | Pseudomonas aeruginosa - metabolism | Trans-Activators - genetics | Bacterial Proteins - metabolism | Pneumonia, Bacterial - genetics | Trans-Activators - metabolism | Mice | Mutation | Acetophenones - metabolism | Chronic Disease | Drosophila melanogaster | Disease Models, Animal | Infection | Phenotype | Chronic diseases | Physiological aspects | Genetic aspects | Research | Gene expression | Health aspects | Scholarships & fellowships | Microorganisms | Microbiology | Bacteria | Infections | Bacteriology | Molecular weight | Acetophenones | Biotechnology | Quorum Sensing | Trans-Activators | Pneumonia, Bacterial | Bacterial Proteins | Life Sciences | Computer Science | Pseudomonas aeruginosa | Pseudomonas Infections | Gene Expression Regulation, Bacterial
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2011, Volume 7, Issue 8, p. e1002204
Klebsiella pneumoniae causes significant morbidity and mortality worldwide, particularly amongst hospitalized individuals. The principle mechanism for... 
CELLULOSE SYNTHESIS | ESCHERICHIA-COLI | CLONING VEHICLES | MICROBIOLOGY | CYCLIC DIGUANYLATE | PILZ DOMAIN | SIGNAL-TRANSDUCTION | VIROLOGY | INTENSIVE-CARE-UNIT | PSEUDOMONAS-AERUGINOSA | SALMONELLA-TYPHIMURIUM | PHASE VARIATION | PARASITOLOGY | Amino Acid Sequence | Phosphoric Diester Hydrolases - metabolism | Phosphorus-Oxygen Lyases - genetics | Transcriptional Activation | Bacterial Proteins - genetics | Molecular Sequence Data | Escherichia coli Proteins - metabolism | Phosphoric Diester Hydrolases - genetics | Fimbriae, Bacterial - genetics | Biofilms | DNA, Bacterial - genetics | Cyclic GMP - analogs & derivatives | Plasmids | Gene Deletion | Cyclic GMP - genetics | Klebsiella pneumoniae - genetics | Escherichia coli Proteins - genetics | Klebsiella pneumoniae - growth & development | Protein Binding | Bacterial Proteins - metabolism | Klebsiella pneumoniae - metabolism | Gene Expression Regulation, Bacterial | Phosphorus-Oxygen Lyases - metabolism | Fimbriae, Bacterial - metabolism | Klebsiella | Polymerase chain reaction | Usage | Gene mutations | Physiological aspects | Research | Microbial mats | Proteins | Medical equipment | Antibiotics | E coli | Pathogenesis | Standard deviation | Nosocomial infections | Gene expression | Experiments | Urogenital system | Bacteriology | Deoxyribonucleic acid--DNA | Deoxyribonucleic acid | DNA
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2008, Volume 14, Issue 3, pp. 275 - 281
Journal Article