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1. Full Text Bacterial Coinfection in Influenza: A Grand Rounds Review
by Chertow, Daniel S and Memoli, Matthew J
JAMA, ISSN 0098-7484, 01/2013, Volume 309, Issue 3, pp. 275 - 282
Bacterial coinfection complicated nearly all influenza deaths in the 1918 influenza pandemic and up to 34% of 2009 pandemic influenza A(H1N1) infections... 
UNITED-STATES | MEDICINE, GENERAL & INTERNAL | COMMUNITY-ACQUIRED PNEUMONIA | ADVISORY-COMMITTEE | STREPTOCOCCUS-PNEUMONIAE | VIRUS | RESPIRATORY-TRACT COMPLICATIONS | PANDEMIC INFLUENZA | STAPHYLOCOCCUS-AUREUS | GLOBAL MORTALITY | H1N1 INFLUENZA | Community-Acquired Infections - diagnosis | Influenza Vaccines - administration & dosage | Coinfection | Humans | Middle Aged | Critical Illness | Male | Influenza, Human - complications | Staphylococcal Infections - complications | Anti-Bacterial Agents - therapeutic use | Community-Acquired Infections - drug therapy | Pneumonia, Bacterial - mortality | Fatal Outcome | Influenza A Virus, H1N1 Subtype | Influenza, Human - mortality | Influenza, Human - diagnosis | Community-Acquired Infections - complications | Influenza, Human - therapy | Community-Acquired Infections - mortality | Staphylococcal Infections - drug therapy | Pneumonia, Bacterial - complications | Pneumonia, Bacterial - diagnosis | Morbidity | Staphylococcal Infections - mortality | Staphylococcal Infections - diagnosis | Critical Care | Pneumonia, Bacterial - drug therapy | Staphylococcus infections | Systematic review | Immunization | Pandemics | Swine flu
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2. Full Text An international multicenter retrospective study of Pseudomonas aeruginosa nosocomial pneumonia: Impact of multidrug resistance
by Micek, Scott T and Wunderink, Richard G and Kollef, Marin H and Chen, Catherine and Rello, Jordi and Chastre, Jean and Antonelli, Massimo and Welte, Tobias and Clair, Bernard and Ostermann, Helmut and Calbo, Esther and Torres, Antoni and Menichetti, Francesco and Schramm, Garrett E and Menon, Vandana
Critical Care, ISSN 1364-8535, 05/2015, Volume 19, Issue 1, p. 219
Introduction: Pseudomonas aeruginosa nosocomial pneumonia (Pa-NP) is associated with considerable morbidity, prolonged hospitalization, increased costs, and... 
HOSPITALIZED-PATIENTS | INFECTIONS | RISK-FACTORS | VENTILATOR-ASSOCIATED PNEUMONIA | ACQUIRED PNEUMONIA | CARE-ASSOCIATED PNEUMONIA | BACTEREMIA | CARBAPENEMASE | PREVALENCE | PATHOGENS | CRITICAL CARE MEDICINE | Pseudomonas aeruginosa - isolation & purification | Humans | Middle Aged | Cross Infection - mortality | Male | Pseudomonas Infections - mortality | Hospital Mortality - trends | Anti-Bacterial Agents - therapeutic use | Pneumonia, Bacterial - mortality | Adult | Female | Retrospective Studies | Pseudomonas Infections - drug therapy | Pseudomonas Infections - diagnosis | Mortality - trends | Pneumonia, Bacterial - diagnosis | Pseudomonas aeruginosa - drug effects | Cross Infection - drug therapy | Internationality | Hospitalization - trends | Cross Infection - diagnosis | Pneumonia, Bacterial - drug therapy | Aged | Anti-Bacterial Agents - pharmacology | Drug Resistance, Multiple, Bacterial - drug effects | Medical research | Drug resistance in microorganisms | Pneumonia | Bacterial pneumonia | Mortality | Medicine, Experimental | Diabetes | Comparative analysis | France | Health aspects | Risk factors | Patient safety | Multidrug resistant organisms | Drug resistance | Research
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3. Full Text Costs of Healthcare- and Community-Associated Infections With Antimicrobial-Resistant Versus Antimicrobial-Susceptible Organisms
by Matthew J. Neidell and Bevin Cohen and Yoko Furuya and Jennifer Hill and Christie Y. Jeon and Sherry Glied and Elaine L. Larson
Clinical Infectious Diseases, ISSN 1058-4838, 9/2012, Volume 55, Issue 6, pp. 807 - 815
Objective. We compared differences in the hospital charges, length of hospital stay, and mortality between patients with healthcare- and community-associated... 
Hospital costs | Hospitals | Cost estimates | Antimicrobials | Hospital admissions | Urinary tract infections | Infections | Censorship | ARTICLES AND COMMENTARIES | Staphylococcus aureus | Length of stay | MORTALITY | INFECTIOUS DISEASES | ESCHERICHIA-COLI | EUROPEAN HOSPITALS | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | IMMUNOLOGY | METHICILLIN-RESISTANCE | ENTEROCOCCUS | BACTEREMIA | STAPHYLOCOCCUS-AUREUS | BURDEN | BLOOD-STREAM INFECTIONS | Cross Infection - economics | Community-Acquired Infections - epidemiology | Length of Stay - economics | Urinary Tract Infections - mortality | Humans | Middle Aged | Cross Infection - mortality | Drug Resistance, Bacterial | Bacteremia - mortality | Male | Urinary Tract Infections - economics | Bacteremia - economics | Pneumonia, Bacterial - economics | Case-Control Studies | Bacteremia - microbiology | Hospital Charges - statistics & numerical data | Pneumonia, Bacterial - mortality | Aged, 80 and over | Adult | Female | Urinary Tract Infections - microbiology | Retrospective Studies | Bacterial Infections - microbiology | Length of Stay - statistics & numerical data | Cross Infection - epidemiology | Databases, Factual | Community-Acquired Infections - mortality | Pneumonia, Bacterial - microbiology | Bacterial Infections - economics | Community-Acquired Infections - economics | Pneumonia, Bacterial - epidemiology | Urinary Tract Infections - epidemiology | Health Care Costs | Cross Infection - microbiology | Bacterial Infections - epidemiology | Survival Analysis | Bacteremia - epidemiology | New York City - epidemiology | Aged | Community-Acquired Infections - microbiology | Bacterial Infections - mortality | Infection | Blood-borne diseases | Care and treatment | Economic aspects | Research | Drug resistance | Medical care, Cost of | and Commentaries
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4. Full Text Mortality due to KPC carbapenemase-producing Klebsiella pneumoniae infections: Systematic review and meta-analysis: Mortality due to KPC Klebsiella pneumoniae infections
by Ramos-Castañeda, Jorge A and Ruano-Ravina, Alberto and Barbosa-Lorenzo, Raquel and Paillier-Gonzalez, Jaime E and Saldaña-Campos, Javier C and Salinas, Diego F and Lemos-Luengas, Elkin V
Journal of Infection, ISSN 0163-4453, 05/2018, Volume 76, Issue 5, pp. 438 - 448
Introduction: KPC carbapenemase-producing Klebsiella pneumoniae (KPC-KP) has become a major public health challenge. Accordingly, this study sought to use a... 
Carbapenemase | Bacterial resistance | Mortality | Klebsiella pneumoniae | KPC | MOLECULAR CHARACTERIZATION | ACUTE KIDNEY INJURY | INFECTIOUS DISEASES | RISK-FACTORS | K.-PNEUMONIAE | POLYMYXIN-B | NOSOCOMIAL OUTBREAK | GRAM-NEGATIVE BACTERIA | INTENSIVE-CARE-UNIT | EXTENSIVELY DRUG-RESISTANT | BLOOD-STREAM INFECTIONS | Public Health | Klebsiella Infections - drug therapy | Klebsiella pneumoniae - drug effects | Humans | Bacteremia - drug therapy | Bacteremia - mortality | Clinical Trials as Topic | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Klebsiella pneumoniae - pathogenicity | Pneumonia, Bacterial - mortality | Klebsiella pneumoniae - enzymology | Bacterial Proteins - metabolism | Klebsiella Infections - mortality | Pneumonia, Bacterial - drug therapy | beta-Lactamases - metabolism | Brazil - epidemiology | Cross Infection - epidemiology | Medical research | Pneumonia | Analysis | Bacterial pneumonia | Medicine, Experimental | Drug resistance | Health aspects | Epidemiology
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5. Full Text Timing and impact of infections in acute pancreatitis
by Besselink, M. G and van Santvoort, H. C and Boermeester, M. A and Nieuwenhuijs, V. B and van Goor, H and Dejong, C. H. C and Schaapherder, A. F and Gooszen, H. G and van Ramshorst, B and Bollen, T. L and Weusten, B. L and Timmer, R and Akkermans, L. M and Cirkel, G. A and Zeguers, V and Roeterdink, A and Rijnhart, H. G and Schwartz, M. P and van Leeuwen, M. S and Ridwan, B. U and Witteman, B. J and Kruyt, P. M and van Laarhoven, C. J and xler, T. A and Ploeg, R. J and Hofker, H. S and Kruijt Spanjer, M. R and Buitenhuis, H. T and van Vliet, S. U and Ramcharan, S and Nooteboom, A and Jansen, J. B and Bongaerts, G. T and Buscher, H. C and Brink, M. A and Mundt, M and Frankhuisen, R and Consten, E. C and van Ruler, O and Gouma, D. J and Bruno, M. J and Rutten, J. P and Tan, A. C and Rosman, C and Ootes, L and Houben, B and Haasnoot, A and van Eijck, C. H and van der Wal, J. B. C and van 't Hof, G and Kuipers, E. J and Wahab, P and Spillenaar Bilgen, E. J and van Embden, P and Kubben, F. J and van der Harst, E and Lange, J. F and Wijffels, N. A and van Walraven, L. A and Cuesta, M. A and Mulder, C. J and Dutch Acute Pancreatitis Study Grp and Dutch Acute Pancreatitis Study Group and for the Dutch Acute Pancreatitis Study Group
British journal of surgery, ISSN 0007-1323, 2009, Volume 96, Issue 3, pp. 267 - 273
BACKGROUND: Although infected necrosis is an established cause of death in acute pancreatitis, the impact of bacteraemia and pneumonia is less certain.... 
MORTALITY | SURGERY | CONTROLLED-TRIAL | ENTERAL NUTRITION | NECROSIS | ACUTE NECROTIZING PANCREATITIS | DOUBLE-BLIND | NEEDLE-ASPIRATION HELPFUL | COMPLICATIONS | ANTIBIOTIC-TREATMENT | ORGAN FAILURE | Enteral Nutrition - methods | Acute Disease | Prognosis | Humans | Middle Aged | Gram-Positive Bacterial Infections - mortality | Pancreatitis, Acute Necrotizing - mortality | Bacteremia - mortality | Male | Pancreatitis - mortality | Pneumonia, Bacterial - prevention & control | Anti-Bacterial Agents - therapeutic use | Bacteremia - prevention & control | Time Factors | Pneumonia, Bacterial - mortality | Adult | Female | Aged | Mycoses - mortality | Pancreatitis - microbiology | Gram-Negative Bacterial Infections - mortality
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6. Full Text Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness
by David M. Morens and Jeffery K. Taubenberger and Anthony S. Fauci
The Journal of Infectious Diseases, ISSN 0022-1899, 10/2008, Volume 198, Issue 7, pp. 962 - 970
Background. Despite the availability of published data on 4 pandemics that have occurred over the past 120 years, there is little modern information on the... 
Pathology | Epidemics | Viral pneumonia | Pandemics | Autopsies | Lungs | Pneumococcal pneumonia | Bacterial pneumonia | Bacteria | Viruses | A VIRUS | PNEUMOCOCCUS | INFECTIOUS DISEASES | RESPIRATORY-TRACT | X-RAY | ASIAN INFLUENZA | INFECTION | COMPLICATIONS | PATHOLOGY | EPIDEMIC | EXPRESSION | Lung - pathology | Time Factors | Autopsy | Disease Outbreaks | Humans | Pneumonia, Bacterial - mortality | Influenza, Human - mortality | Lung - immunology | Influenza A Virus, H5N1 Subtype - isolation & purification | Pneumonia | United States | Influenza | Patient outcomes | Emergency management | Influence | Reports
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7. Full Text Macrolides and Mortality in Critically Ill Patients With Community-Acquired Pneumonia: A Systematic Review and Meta-Analysis
by Sligl, Wendy I and Asadi, Leyla and Eurich, Dean T and Tjosvold, Lisa and Marrie, Thomas J and Majumdar, Sumit R
Critical Care Medicine, ISSN 0090-3493, 02/2014, Volume 42, Issue 2, pp. 420 - 432
OBJECTIVE:Some studies suggest better outcomes with macrolide therapy for critically ill patients with community-acquired pneumonia. To further explore this,... 
Community-Acquired Pneumonia | Critical Care | Intensive Care | Macrolide | Mortality | Systematic Review | COMBINATION ANTIBIOTIC-THERAPY | HOSPITALIZED-PATIENTS | INTERNATIONAL-COHORT | intensive care | VENTILATOR-ASSOCIATED PNEUMONIA | critical care | community-acquired pneumonia | systematic review | INTENSIVE-CARE-UNIT | mortality | PNEUMOCOCCAL PNEUMONIA | INFECTIOUS-DISEASES-SOCIETY | ELDERLY-PATIENTS | EPIDEMIOLOGY | macrolide | SEVERE SEPSIS | CRITICAL CARE MEDICINE | Anti-Bacterial Agents - therapeutic use | Community-Acquired Infections - mortality | Community-Acquired Infections - drug therapy | Humans | Pneumonia, Bacterial - mortality | Critical Illness | Pneumonia, Bacterial - drug therapy | Macrolides - therapeutic use
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8. Full Text Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study
by Lambert, Marie-Laurence, Dr and Suetens, Carl, MD and Savey, Anne, MD and Palomar, Mercedes, MD and Hiesmayr, Michael, Prof and Morales, Ingrid, MD and Agodi, Antonella, Prof and Frank, Uwe, Prof and Mertens, Karl, MSc and Schumacher, Martin, Prof and Wolkewitz, Martin, PhD
Lancet Infectious Diseases, The, ISSN 1473-3099, 2011, Volume 11, Issue 1, pp. 30 - 38
Summary Background Patients admitted to intensive-care units are at high risk of health-care-associated infections, and many are caused by... 
Infectious Disease | MORTALITY | INFECTIOUS DISEASES | METAANALYSIS | REAPPRAISAL | VENTILATOR-ASSOCIATED PNEUMONIA | BACTEREMIA | SURVEILLANCE | HOSPITALS | NOSOCOMIAL INFECTION | CRITICALLY-ILL PATIENTS | BLOOD-STREAM INFECTIONS | Humans | Middle Aged | Bacteria - drug effects | Cross Infection - mortality | Drug Resistance, Bacterial | Bacteremia - mortality | Male | Bacteremia - microbiology | Anti-Bacterial Agents - therapeutic use | Pneumonia, Bacterial - mortality | Bacteria - classification | Adult | Female | Length of Stay - statistics & numerical data | Intensive Care Units | Pneumonia, Bacterial - microbiology | Europe | Bacteremia - drug therapy | Treatment Outcome | Cross Infection - drug therapy | Bacteria - isolation & purification | Cross Infection - microbiology | Pneumonia, Bacterial - drug therapy | Aged | Anti-Bacterial Agents - pharmacology | Cohort Studies | Drug resistance in microorganisms | Medical research | Pneumonia | Care and treatment | Pain | Bacterial pneumonia | Patient outcomes | Environmental health | Medicine, Experimental | Cross infection | Nosocomial infections | Public health | Pathogens | Mortality | Data processing | Drug resistance | Risk factors | Infection | Pathogenicity | Microorganisms | Oxacillin | Cephalosporins | Models | Ceftazidime | Life Sciences | Other
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9. Full Text Complicated Skin and Skin-Structure Infections and Catheter-Related Bloodstream Infections: Noninferiority of Linezolid in a Phase 3 Study
by Mark H. Wilcox and Kenneth J. Tack and Emilio Bouza and Daniel L. Herr and Bernhard R. Ruf and M. Marian Ijzerman and Rodney V. Croos-Dabrera and Mark J. Kunkel and Charles Knirsch
Clinical Infectious Diseases, ISSN 1058-4838, 1/2009, Volume 48, Issue 2, pp. 203 - 212
Background. Catheter-related bloodstream infection (CRBSI) causes substantial morbidity and mortality, but few randomized, controlled studies have been... 
Control groups | Pathogens | Health outcomes | Microbiology | Mortality | Articles and Commentaries | Infections | Dosage | Catheters | Bacteremia | Blood | INFECTIOUS DISEASES | MULTICENTER | SAFETY | MICROBIOLOGY | IMMUNOLOGY | INTENSIVE-CARE UNIT | ATTRIBUTABLE MORTALITY | VANCOMYCIN | COSTS | BACTEREMIA | DOUBLE-BLIND | CRITICALLY-ILL PATIENTS | NOSOCOMIAL PNEUMONIA | Linezolid | Humans | Middle Aged | Cross Infection - mortality | Gram-Positive Bacterial Infections - mortality | Bacteremia - mortality | Male | Oxazolidinones - adverse effects | Skin Diseases, Bacterial - drug therapy | Oxazolidinones - therapeutic use | Anti-Bacterial Agents - therapeutic use | Acetamides - therapeutic use | Acetamides - adverse effects | Aged, 80 and over | Catheter-Related Infections - mortality | Adult | Female | Anti-Bacterial Agents - adverse effects | Bacteremia - drug therapy | Gram-Negative Bacterial Infections - drug therapy | Skin Diseases, Bacterial - mortality | Cross Infection - drug therapy | Catheter-Related Infections - drug therapy | Vancomycin - adverse effects | Vancomycin - therapeutic use | Adolescent | Aged | Gram-Positive Bacterial Infections - drug therapy | Gram-Negative Bacterial Infections - mortality | Infectious skin diseases | Blood-borne diseases | Care and treatment | Dosage and administration | Research | Index Medicus
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10. Full Text Antibiotic Treatment Strategies for Community-Acquired Pneumonia in Adults
by Postma, Douwe F and van Werkhoven, Cornelis H and van Elden, Leontine J.R and Thijsen, Steven F.T and Hoepelman, Andy I.M and Kluytmans, Jan A.J.W and Boersma, Wim G and Compaijen, Clara J and van der Wall, Eva and Prins, Jan M and Oosterheert, Jan J and Bonten, Marc J.M and CAP-START Study Grp and CAP-START Study Group
The New England Journal of Medicine, ISSN 0028-4793, 04/2015, Volume 372, Issue 14, pp. 1312 - 1323
Antimicrobial choices for community-acquired pneumonia in hospitalized patients who do not require ICU-level care continue to be debated. In this trial,... 
NONINFERIORITY | MEDICINE, GENERAL & INTERNAL | DESIGN | THERAPY | MANAGEMENT | ATYPICAL PATHOGENS | CLINICAL-TRIALS | GUIDELINES | BETA-LACTAM MONOTHERAPY | AZITHROMYCIN | ECONOMIC BURDEN | Length of Stay | Community-Acquired Infections - mortality | Administration, Oral | Humans | Middle Aged | Fluoroquinolones - therapeutic use | Male | Cross-Over Studies | Anti-Bacterial Agents - therapeutic use | Community-Acquired Infections - drug therapy | Pneumonia, Bacterial - mortality | Intention to Treat Analysis | Adult | Female | Pneumonia, Bacterial - drug therapy | Aged | Drug Therapy, Combination | Macrolides - therapeutic use | beta-Lactams - therapeutic use | Pneumonia | Usage | Community-acquired infections | Bacterial pneumonia | Beta lactam antibiotics | Drug therapy, Combination | Research | Drug therapy | Health aspects | Motivation | Antibiotics | Mortality | Adults | Patients
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11. Full Text Deaths from bacterial pneumonia during 1918-19 influenza pandemic
by Brundage, John F and Shanks, G. Dennis
Emerging Infectious Diseases, ISSN 1080-6040, 08/2008, Volume 14, Issue 8, pp. 1193 - 1199
Deaths during the 1918-19 influenza pandemic have been attributed to a hypervirulent influenza strain. Hence, preparations for the next pandemic focus almost... 
INFECTIOUS DISEASES | STREPTOCOCCUS-PNEUMONIAE | VIRUS | DISEASE | STAPHYLOCOCCUS-AUREUS | 20TH-CENTURY | PREPAREDNESS | IMMUNOLOGY | EPIDEMIC | VACCINES | INSIGHTS | History, 20th Century | Humans | Pneumonia, Bacterial - complications | Virulence | Influenza, Human - epidemiology | Influenza, Human - complications | Pneumonia, Bacterial - epidemiology | Disease Outbreaks | Pneumonia, Bacterial - mortality | Influenza, Human - mortality | Influenza, Human - history | Orthomyxoviridae - pathogenicity | Pneumonia, Bacterial - history | Prevention | Antiviral agents | Development and progression | Care and treatment | Health aspects | Influenza | epidemiology | opportunistic infections | public health practice | bacterial pneumonia | infection control | history | Historical Review | pandemic | mass immunization
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12. Full Text Prognostic Accuracy of the SOFA Score, SIRS Criteria, and qSOFA Score for In-Hospital Mortality Among Adults With Suspected Infection Admitted to the Intensive Care Unit
by Raith, Eamon P and Udy, Andrew A and Bailey, Michael and McGloughlin, Steven and MacIsaac, Christopher and Bellomo, Rinaldo and Pilcher, David V and CORE and ANZICS and Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes and Resource Evaluation (CORE) and for the Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes and Resource Evaluation (CORE)
JAMA, ISSN 0098-7484, 01/2017, Volume 317, Issue 3, pp. 290 - 300
IMPORTANCE: The Sepsis-3 Criteria emphasized the value of a change of 2 or more points in the Sequential [Sepsis-related] Organ Failure Assessment (SOFA)... 
CLINICAL-CRITERIA | MEDICINE, GENERAL & INTERNAL | AUSTRALIA | NEW-ZEALAND | INTERNATIONAL CONSENSUS DEFINITIONS | SEPTIC SHOCK SEPSIS-3 | RISK | ORGAN FAILURE | ANZROD MODEL | PREDICTION | Prognosis | Hospital Mortality | Systemic Inflammatory Response Syndrome | Area Under Curve | Humans | Middle Aged | Intensive Care Units - statistics & numerical data | Male | Australia - epidemiology | Sepsis - mortality | Pneumonia, Bacterial - mortality | Adult | Female | Organ Dysfunction Scores | ROC Curve | Retrospective Studies | Length of Stay - statistics & numerical data | New Zealand - epidemiology | Infection | Intensive care units | Care and treatment | Critically ill | Management | Diagnosis | Health aspects | Intensive care | Adults | Infections | Patient admissions | Mortality
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