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The EMBO Journal, ISSN 0261-4189, 12/2007, Volume 26, Issue 24, pp. 5020 - 5032
The signaling lipid molecule 15‐deoxy‐delta 12,14‐prostaglandin J2 (15d‐PGJ2) has multiple cellular functions, including anti‐inflammatory and antineoplastic... 
15d‐PGJ2 | translation | proliferation | inflammation | eIF4A | Translation | Inflammation | Proliferation | 15d-PGJ2 | TRANSFORMATION SUPPRESSOR PDCD4 | KAPPA-B ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | BINDING-PROTEIN | INITIATION CODON | CELL BIOLOGY | HEPATITIS-C VIRUS | PATHWAY | STRESS GRANULE FORMATION | PRODUCT PATEAMINE-A | RNA HELICASE EIF4A | Tumor Necrosis Factor-alpha - metabolism | Arachidonic Acid - metabolism | Protein Biosynthesis | Sodium Compounds - metabolism | Hypoglycemic Agents - metabolism | Humans | TNF Receptor-Associated Factor 2 - genetics | Cytoplasmic Granules - chemistry | PPAR gamma - metabolism | Anti-Inflammatory Agents - metabolism | Chromans - metabolism | Poly(A)-Binding Proteins - metabolism | Prostaglandin D2 - metabolism | Cytoplasmic Granules - metabolism | Eukaryotic Initiation Factor-2 - metabolism | Prostaglandin D2 - analogs & derivatives | T-Cell Intracellular Antigen-1 | Eukaryotic Initiation Factor-4A - genetics | Emetine - metabolism | Enzyme Inhibitors - metabolism | Poly(A)-Binding Proteins - genetics | Gene Expression Regulation | TNF Receptor-Associated Factor 2 - metabolism | Protein Synthesis Inhibitors - metabolism | Thiazolidinediones - metabolism | Arsenites - metabolism | Dinoprostone - metabolism | Eukaryotic Initiation Factor-2 - genetics | Inflammation - genetics | Cyclopentanes - metabolism | Signal Transduction - physiology | Prostaglandins A - metabolism | HeLa Cells | Eukaryotic Initiation Factor-4A - metabolism | Lipids | Cellular biology | Molecular biology | Binding sites | Inflammatory diseases | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 02/2016, Volume 7, Issue 1, pp. 10660 - 10660
Embryonic stem cells (ESCs) represent a transient biological state, where pluripotency is coupled with fast proliferation. ESCs display a constitutively active... 
GENOMIC INSTABILITY | PROTEIN | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | IN-VIVO | SELF-RENEWAL | PLURIPOTENCY | HOMOLOGOUS RECOMBINATION | DARK SIDE | CYCLE | REVERSAL | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 3, pp. 520 - 533
The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its co-factor Mtr4p/hMTR4, which links to... 
RNA exosome | PAXT connection | nuclear RNA decay | poly(A) tail | NEXT complex | TELOMERASE RNA | MESSENGER-RNA | CRYPTIC UNSTABLE TRANSCRIPTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RNA-QUALITY-CONTROL | MOLECULAR ARCHITECTURE | TARGETING COMPLEX | POLY(A)-BINDING PROTEIN | 3'-END MATURATION | POLY(A) TAIL LENGTH | BINDING-PROTEINS | CELL BIOLOGY | RNA Helicases - metabolism | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Humans | RNA, Messenger - metabolism | Cell Nucleus - metabolism | HEK293 Cells | Exosome Multienzyme Ribonuclease Complex - metabolism | RNA Helicases - genetics | Exosome Multienzyme Ribonuclease Complex - genetics | Nuclear Proteins - genetics | Poly(A)-Binding Protein I - genetics | Binding Sites | RNA-Binding Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Carrier Proteins - antagonists & inhibitors | Poly(A)-Binding Protein I - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Poly A - genetics | Transcription Factors - genetics | RNA Stability - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Poly A - metabolism | Carrier Proteins - metabolism | Cell Nucleus - genetics | Nuclear Proteins - antagonists & inhibitors | Poly(A)-Binding Protein I - antagonists & inhibitors | Protein Binding | HeLa Cells | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Zinc compounds | RNA | Molecular biology | Protein binding | Index Medicus
Journal Article
FEBS Journal, ISSN 1742-464X, 03/2015, Volume 282, Issue 5, pp. 874 - 890
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2009, Volume 36, Issue 4, pp. 571 - 582
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2016, Volume 44, Issue 12, pp. 5743 - 5757
DNA double-strand breaks (DSBs) are toxic lesions, which if improperly repaired can result in cell death or genomic instability. DSB repair is usually... 
FIDELITY | REPAIR PATHWAY | RESECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CTIP | LIGASE-III | DOUBLE-STRAND BREAKS | DIRECTED REPAIR | BRCA1 | DNA-POLYMERASE-THETA | DAMAGE | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Humans | DNA Breaks, Double-Stranded | DNA-Directed DNA Polymerase - genetics | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | BRCA2 Protein - antagonists & inhibitors | BRCA1 Protein - metabolism | Base Sequence | DNA End-Joining Repair | Replication Protein A - genetics | Replication Protein A - antagonists & inhibitors | Biological Assay | Osteoblasts - cytology | Epithelial Cells - cytology | Nuclear Proteins - genetics | Fibroblasts - metabolism | Recombinational DNA Repair | Nuclear Proteins - metabolism | Replication Protein A - metabolism | DNA - metabolism | DNA-Binding Proteins - genetics | Sequence Homology, Nucleic Acid | BRCA1 Protein - genetics | Carrier Proteins - genetics | Poly(ADP-ribose) Polymerases - metabolism | Sequence Alignment | BRCA2 Protein - metabolism | Carrier Proteins - metabolism | Poly(ADP-ribose) Polymerases - genetics | BRCA1 Protein - antagonists & inhibitors | Cell Line, Tumor | Fibroblasts - cytology | DNA-Directed DNA Polymerase - metabolism | Mutation | Osteoblasts - metabolism | BRCA2 Protein - genetics | RNA, Small Interfering - metabolism | Index Medicus | Genome Integrity, Repair and
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 05/2005, Volume 20, Issue 5, pp. 848 - 857
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 05/2010, Volume 29, Issue 9, pp. 1585 - 1599
Journal Article
Science, ISSN 0036-8075, 8/2007, Volume 317, Issue 5842, pp. 1224 - 1227
Cellular internal ribosome entry sites (IRESs) are untranslated segments of mRNA transcripts thought to initiate protein synthesis in response to environmental... 
Yeasts | Cell growth | Messenger RNA | Peptide initiation factors | Five prime untranslated regions | RNA | Genes | Ribosomes | Reports | Open reading frames | Cells | COMPLEX | CELLULAR MESSENGER-RNAS | PROTEIN | PATHWAY | INITIATION-FACTOR | MULTIDISCIPLINARY SCIENCES | GROWTH | MECHANISMS | EIF4G | SACCHAROMYCES-CEREVISIAE | Adaptation, Physiological | Protein Biosynthesis | Saccharomyces cerevisiae - genetics | Saccharomyces cerevisiae Proteins - biosynthesis | 5' Untranslated Regions - genetics | 5' Untranslated Regions - metabolism | Peptide Chain Initiation, Translational | Eukaryotic Initiation Factor-4G - metabolism | RNA Caps - metabolism | RNA, Messenger - metabolism | Saccharomyces cerevisiae - metabolism | Nuclear Proteins - biosynthesis | Poly(A)-Binding Proteins - metabolism | Trans-Activators - genetics | Genes, Fungal | RNA, Fungal - genetics | Trans-Activators - biosynthesis | Nuclear Proteins - genetics | Nucleic Acid Conformation | RNA, Fungal - chemistry | RNA, Messenger - genetics | Nuclear Proteins - metabolism | Saccharomyces cerevisiae Proteins - genetics | RNA, Fungal - metabolism | Poly A - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Glucose - metabolism | RNA, Messenger - chemistry | Trans-Activators - metabolism | Eukaryotic Initiation Factor-4G - genetics | Saccharomyces cerevisiae - growth & development | Protein biosynthesis | Research | Yeast fungi | Genetic translation | Proteins | Signal transduction | Yeast | Mutation | Molecular biology | Stress | Index Medicus
Journal Article