X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (10457) 10457
Publication (1136) 1136
Book Review (795) 795
Book Chapter (107) 107
Conference Proceeding (41) 41
Magazine Article (6) 6
Newspaper Article (6) 6
Book / eBook (4) 4
Dissertation (4) 4
Data Set (2) 2
Paper (2) 2
Trade Publication Article (2) 2
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (9163) 9163
animals (4776) 4776
humans (4340) 4340
mice (2052) 2052
biochemistry & molecular biology (1968) 1968
poly (1927) 1927
female (1647) 1647
base sequence (1542) 1542
poly polymerase (1514) 1514
poly polymerases - metabolism (1353) 1353
apoptosis (1313) 1313
male (1294) 1294
molecular sequence data (1268) 1268
poly a - genetics (1202) 1202
rna, messenger - genetics (1177) 1177
cell biology (1102) 1102
oncology (1083) 1083
amino acid sequence (1000) 1000
rats (961) 961
cell line (958) 958
expression (944) 944
proteins (924) 924
genes (920) 920
rna, messenger - metabolism (920) 920
gene expression (905) 905
protein biosynthesis (897) 897
cancer (879) 879
cell line, tumor (873) 873
biotechnology & applied microbiology (872) 872
analysis (857) 857
cloning, molecular (823) 823
research (811) 811
cells, cultured (783) 783
dna (769) 769
apoptosis - drug effects (758) 758
poly a - metabolism (747) 747
transcription, genetic (743) 743
mutation (737) 737
rna - genetics (702) 702
cells (671) 671
microbiology (647) 647
activation (624) 624
rna (624) 624
kinetics (592) 592
poly i-c - pharmacology (591) 591
immunology (584) 584
poly polymerases - genetics (571) 571
pharmacology & pharmacy (566) 566
transfection (556) 556
genetic aspects (554) 554
rna, messenger (542) 542
multidisciplinary sciences (537) 537
dna damage (522) 522
protein (520) 520
genetics & heredity (518) 518
molecular weight (515) 515
article (499) 499
gene (496) 496
poly polymerase-1 (473) 473
poly polymerase inhibitors (470) 470
dna repair (468) 468
enzymes (468) 468
nucleic acid hybridization (467) 467
in-vitro (444) 444
in-vivo (431) 431
biotechnology (428) 428
signal transduction (428) 428
tumors (419) 419
gene expression regulation (414) 414
physiological aspects (410) 410
dna - genetics (409) 409
polymers (396) 396
bacteria (392) 392
health aspects (386) 386
time factors (384) 384
research article (382) 382
poly a - isolation & purification (381) 381
oxidative stress (379) 379
deoxyribonucleic acid--dna (378) 378
inhibition (371) 371
blotting, northern (369) 369
blotting, western (368) 368
cell survival - drug effects (368) 368
escherichia-coli (357) 357
breast cancer (351) 351
mice, inbred c57bl (350) 350
gene-expression (347) 347
messenger-rna (344) 344
biosynthesis (343) 343
phosphorylation (342) 342
identification (337) 337
chemotherapy (334) 334
medicine (333) 333
escherichia coli - genetics (332) 332
antineoplastic agents - pharmacology (329) 329
caspases - metabolism (327) 327
rna - isolation & purification (324) 324
biophysics (321) 321
polymerase chain reaction (319) 319
tumor cells, cultured (311) 311
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (10360) 10360
Russian (51) 51
Chinese (26) 26
German (21) 21
Japanese (20) 20
French (15) 15
Polish (7) 7
Korean (3) 3
Spanish (2) 2
Ukrainian (2) 2
Czech (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Biological Chemistry, ISSN 0021-9258, 11/2008, Volume 283, Issue 48, pp. 33394 - 33405
Micro-RNAs are similar to 21-25-nucleotide-long noncoding RNAs that regulate gene expression primarily at the post-transcriptional level in animals. Here, we... 
SURVIVAL | C/EBP-ALPHA | MICRORNA FUNCTION | THERAPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | TUMOR-SUPPRESSOR | TARGETS | DEGRADATION | HUMAN HEPATOCELLULAR CARCINOMAS | EXPRESSION | Lung Neoplasms - drug therapy | Histone Deacetylases - biosynthesis | Antibiotics, Antineoplastic - pharmacology | Caspase 7 - biosynthesis | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Apoptosis - genetics | MicroRNAs - metabolism | Proto-Oncogene Proteins - biosynthesis | RNA, Neoplasm - metabolism | Receptors, Growth Factor - genetics | Caspase 3 - genetics | Caspase 3 - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Lung Neoplasms - genetics | Forkhead Transcription Factors - biosynthesis | Histone Deacetylases - genetics | Caspase 7 - genetics | Cell Survival | Proto-Oncogene Proteins c-met | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Poly(ADP-ribose) Polymerases - biosynthesis | Down-Regulation - drug effects | Forkhead Transcription Factors - genetics | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Down-Regulation - genetics | Animals | Poly(ADP-ribose) Polymerases - genetics | Repressor Proteins - biosynthesis | Mice, Nude | Myeloid Cell Leukemia Sequence 1 Protein | Receptors, Growth Factor - biosynthesis | Cell Line, Tumor | Proto-Oncogene Proteins c-pim-1 - genetics | RNA, Neoplasm - genetics | Mice | MicroRNAs - genetics | Poly (ADP-Ribose) Polymerase-1 | Proto-Oncogene Proteins c-bcl-2 - genetics | Proto-Oncogene Proteins c-pim-1 - biosynthesis | Doxorubicin - pharmacology | Cell Movement | Index Medicus | RNA-Mediated Regulation and Noncoding Rnas
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2012, Volume 189, Issue 11, pp. 5304 - 5313
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 02/2014, Volume 208, Issue 1, pp. 47 - 57
HIMOXOL (methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate) is a synthetic derivative of oleanolic acid (OA). HIMOXOL revealed the highest cytotoxic effect among... 
Breast cancer | Autophagy | HIMOXOL | Apoptosis | SIGNALING PATHWAYS | ACTIVATED PROTEIN-KINASE | TRITERPENOIDS | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | SUPPRESSES MIGRATION | DEATH | PROSTATE-CANCER | PHARMACOLOGY & PHARMACY | TOXICOLOGY | MULTIDRUG-RESISTANCE | NF-KAPPA-B | Cell Cycle - genetics | Microtubule-Associated Proteins - genetics | Apoptosis - drug effects | Microtubule-Associated Proteins - metabolism | Humans | Oleanolic Acid - analogs & derivatives | Caspase 3 - metabolism | Caspase 8 - metabolism | Cell Survival - genetics | Oleanolic Acid - pharmacology | Apoptosis - genetics | NF-kappa B - metabolism | Autophagy - drug effects | Breast Neoplasms - metabolism | Caspase 8 - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Cell Death - genetics | Caspase 3 - genetics | Apoptosis Regulatory Proteins - genetics | Female | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Autophagy - genetics | Cell Death - drug effects | bcl-2-Associated X Protein - genetics | Beclin-1 | Cell Survival - drug effects | Membrane Proteins - genetics | bcl-2-Associated X Protein - metabolism | Up-Regulation - genetics | Signal Transduction - genetics | Breast Neoplasms - drug therapy | Apoptosis Regulatory Proteins - metabolism | Up-Regulation - drug effects | Poly(ADP-ribose) Polymerases - metabolism | Breast Neoplasms - genetics | Poly(ADP-ribose) Polymerases - genetics | NF-kappa B - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Mitogen-Activated Protein Kinases - genetics | Poly (ADP-Ribose) Polymerase-1 | Cell Cycle - drug effects | Proto-Oncogene Proteins c-bcl-2 - genetics | Mitogen-Activated Protein Kinases - metabolism | Tumor proteins | Cancer cells | Index Medicus
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2015, Volume 373, Issue 18, pp. 1697 - 1708
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2010, Volume 185, Issue 12, pp. 7573 - 7582
In mammals, IFN regulatory factor (IRF) 3 is a critical player in modulating transcription of type I IFN and IFN-stimulated genes (ISGs). In this study, we... 
TRANSCRIPTION FACTORS | ANTIVIRAL RESPONSE | DOUBLE-STRANDED-RNA | ONCORHYNCHUS-MYKISS | INNATE IMMUNE-RESPONSE | FUNCTIONAL-ANALYSIS | PARALICHTHYS-OLIVACEUS | INDEPENDENT ACTIVATION | IMMUNOLOGY | NF-KAPPA-B | ATLANTIC SALMON | Cell Nucleus - immunology | Mammals - genetics | Transcription, Genetic - drug effects | Interferons - immunology | Interferon Regulatory Factor-3 - genetics | Fish Proteins - genetics | Goldfish - genetics | Phosphorylation - genetics | STAT1 Transcription Factor - metabolism | Cell Nucleus - metabolism | Mammals - immunology | Up-Regulation - physiology | Phosphorylation - immunology | Interferons - genetics | Phosphorylation - drug effects | Active Transport, Cell Nucleus - genetics | Interferon Regulatory Factor-3 - immunology | Fish Proteins - biosynthesis | Mammals - metabolism | Poly I-C - pharmacology | Goldfish - metabolism | Fish Proteins - immunology | STAT1 Transcription Factor - genetics | Goldfish - immunology | STAT1 Transcription Factor - immunology | Up-Regulation - drug effects | Animals | Cell Nucleus - genetics | Active Transport, Cell Nucleus - drug effects | Interferon Regulatory Factor-3 - biosynthesis | Interferons - metabolism | Transcription, Genetic - immunology | Active Transport, Cell Nucleus - immunology | Mutation | Transcription, Genetic - genetics | Evolution, Molecular | Interferon Inducers - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 06/2013, Volume 73, Issue 12, pp. 3683 - 3691
Replication stress and DNA damage activate the ATR-Chk1 checkpoint signaling pathway that licenses repair and cell survival processes. In this study, we... 
CHECKPOINT KINASE 1 | IN-VITRO | ONCOLOGY | XANTHINE DERIVATIVES | DNA-DAMAGE RESPONSE | PROTEIN-KINASE | TUMOR-CELLS | MYELOGENOUS LEUKEMIA-CELLS | RADIOSENSITIZING AGENT | MAMMALIAN-CELLS | CHK1 INHIBITOR | Protein Kinases - metabolism | Protein Kinases - genetics | Humans | Ovarian Neoplasms - pathology | Cell Survival - genetics | Deoxycytidine - pharmacology | Immunoblotting | Sulfones - pharmacology | Cell Cycle Proteins - antagonists & inhibitors | Dose-Response Relationship, Drug | Ovarian Neoplasms - genetics | RNA Interference | BRCA1 Protein - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Female | Antineoplastic Agents - pharmacology | Ovarian Neoplasms - metabolism | Phosphorylation - drug effects | cdc25 Phosphatases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Pyrazoles - pharmacology | Cell Survival - drug effects | Topotecan - pharmacology | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Signal Transduction - genetics | cdc25 Phosphatases - genetics | Ataxia Telangiectasia Mutated Proteins | Cisplatin - pharmacology | Pyrimidines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors | BRCA1 Protein - genetics | Poly(ADP-ribose) Polymerases - metabolism | BRCA2 Protein - metabolism | Signal Transduction - drug effects | Cell Line, Tumor | Benzimidazoles - pharmacology | Checkpoint Kinase 1 | Pyrazines - pharmacology | BRCA2 Protein - genetics | Deoxycytidine - analogs & derivatives | Index Medicus | homologous recombination | ovarian cancer | Poly(ADP-ribose) polymerase | veliparib | gemcitabine | BRCA1 | cisplatin | BRCA2 | topotecan
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e102148 - e102148
Spontaneously hypertensive rat (SHR) is a suitable model for studies of the complications of hypertension. It is known that activation of poly(ADP-ribose)... 
APOPTOSIS | SIGNALING PATHWAYS | OXIDATIVE STRESS | ACTIVATION | ENDOTHELIAL DYSFUNCTION | MULTIDISCIPLINARY SCIENCES | RATS | ANGIOTENSIN-II | ISCHEMIA-REPERFUSION | FAILURE | LEFT-VENTRICULAR HYPERTROPHY | Protein Kinase C - genetics | Phosphorylation | Natriuretic Peptide, Brain - metabolism | Heart Failure - physiopathology | Rats, Inbred WKY | Glycogen Synthase Kinase 3 beta | Hypertension - drug therapy | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Heart Failure - prevention & control | Hypertrophy, Left Ventricular - genetics | Piperidines - pharmacology | Forkhead Transcription Factors - metabolism | Isoenzymes - metabolism | Protein Kinase C - metabolism | Blood Pressure - drug effects | HSP90 Heat-Shock Proteins - genetics | Hypertension - genetics | Hypertrophy, Left Ventricular - drug therapy | Proto-Oncogene Proteins c-akt - metabolism | Heart Failure - etiology | Rats, Inbred SHR | Natriuretic Peptide, Brain - genetics | Signal Transduction | Isoenzymes - genetics | Hypertrophy, Left Ventricular - etiology | Rats | Heart Failure - genetics | Forkhead Transcription Factors - genetics | Glycogen Synthase Kinase 3 - metabolism | Nerve Tissue Proteins - genetics | Poly(ADP-ribose) Polymerase Inhibitors | Hypertension - physiopathology | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | Glycogen Synthase Kinase 3 - genetics | HSP90 Heat-Shock Proteins - metabolism | Hypertension - complications | Hypertrophy, Left Ventricular - physiopathology | Quinazolines - pharmacology | Heart | Brain | Protein kinase C | Poly(ADP-ribose) | AKT protein | Biochemistry | ADP | Blood | Proteins | Signal transduction | Ischemia | Forkhead protein | Blood pressure | Heart failure | Enzymes | Echocardiography | Chemistry | Inhibitors | Isoforms | Fibrosis | Hypertrophy | Hsp90 protein | Congestive heart failure | Kinases | Remodeling | Medical schools | Ribose | Rodents | Cardiology | Pharmaceutical sciences | Hypertension | Brain natriuretic peptide | AKT1 protein | Isoenzymes | Complications | Glycogen | Heat shock proteins | Extracellular signal-regulated kinase | Glycogen synthase kinase 3 | Poly(ADP-ribose) polymerase | Cardiomyocytes | Medicine | Polymerase | Collagen | Ventricle | Laboratory animals | Heat shock | Apoptosis | Index Medicus
Journal Article
Science Signaling, ISSN 1945-0877, 03/2011, Volume 4, Issue 166, pp. ra19 - ra19
Cancer cells acquire resistance to DNA-damaging therapeutic agents, such as cisplatin, but the genetic mechanisms through which this occurs remain unclear. We... 
BREAST-CANCER | APOPTOSIS | PROTEIN | EPITHELIAL-CELLS | TELOMERASE | DNA-DAMAGE | TUMOR-SUPPRESSOR | DEATH | TARGET GENE | EXPRESSION | CELL BIOLOGY | Neoplasms - metabolism | G2 Phase - genetics | Transcriptional Activation - genetics | Humans | Transcriptional Activation - drug effects | Protein Inhibitors of Activated STAT - metabolism | DNA Repair - genetics | G2 Phase - drug effects | Neoplasms - genetics | Tumor Suppressor Proteins - genetics | Protein Inhibitors of Activated STAT - genetics | DNA Damage - genetics | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Nuclear Proteins - genetics | Gene Expression Regulation, Neoplastic - genetics | Cell Division - genetics | DNA Repair - drug effects | Tumor Suppressor Proteins - metabolism | Nuclear Proteins - metabolism | Cisplatin - pharmacology | Nerve Tissue Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Cell Division - drug effects | Neoplasms - drug therapy | Nerve Tissue Proteins - metabolism | Drug Resistance, Neoplasm - genetics | Poly(ADP-ribose) Polymerases - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Mice | Proto-Oncogene Proteins c-myc - genetics | Poly (ADP-Ribose) Polymerase-1 | Adaptor Proteins, Signal Transducing - metabolism | Drug Resistance, Neoplasm - drug effects | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 51, pp. E12005 - E12014
We isolated a strain of human mycoplasma that promotes lymphomagenesis in SCID mice, pointing to a p53-dependent mechanism similar to lymphomagenesis in... 
DnaK | Mycoplasma | DNA repair | Cancer | P53 | POLY(ADP-RIBOSE) POLYMERASE | APOPTOSIS | MULTIDISCIPLINARY SCIENCES | PARP | KAPPA-B | p53 | GENE | PATHWAY | COLORECTAL-CANCER | cancer | INFECTION | EXPRESSION | mycoplasma | Mycoplasma fermentans - genetics | Genes, Bacterial - genetics | Humans | Mycoplasma - pathogenicity | Antineoplastic Agents - therapeutic use | Phylogeny | Sequence Analysis, Protein | Adenosine Triphosphatases - classification | Cell Transformation, Neoplastic - genetics | DNA-Activated Protein Kinase - metabolism | Ubiquitin Thiolesterase - metabolism | Lymphoma - pathology | Mycoplasma fermentans - pathogenicity | Oncogenes | Disease Models, Animal | Molecular Chaperones - classification | Mycoplasma Infections - microbiology | HCT116 Cells | Bacterial Proteins - genetics | Carcinogenesis - genetics | Molecular Chaperones - genetics | Mycoplasma - genetics | Tumor Suppressor Protein p53 - metabolism | Lymphoma - genetics | Poly (ADP-Ribose) Polymerase-1 - metabolism | Lymphoma - microbiology | Mice, SCID | Cell Transformation, Neoplastic - metabolism | HSP70 Heat-Shock Proteins - metabolism | Animals | DNA, Bacterial - genetics | DNA Repair | Adenosine Triphosphatases - genetics | Bacterial Proteins - classification | Mice | Cell Transformation, Neoplastic - drug effects | Sequence Analysis | Health aspects | Transformation | Immunoprecipitation | Microbiology | p53 Protein | Paracrine signalling | Amino acids | Drug resistance | Gene sequencing | Anticancer properties | Proteins | Antitumor agents | DnaK protein | Bacteria | Repair | Deoxyribonucleic acid--DNA | Nucleotide sequence | Hsp70 protein | Poly(ADP-ribose) Polymerase 1 | DNA-dependent protein kinase | Transformations (mathematics) | Tumors
Journal Article