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Gynecologic Oncology, ISSN 0090-8258, 2015, Volume 139, Issue 1, pp. 59 - 62
Abstract Purpose To determine the cost-effectiveness of olaparib, a PARP inhibitor, as maintenance therapy for platinum-sensitive (PS) recurrent ovarian... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | BRCA | PARP inhibitiors | Olaparib | Cost-effectiveness | Ovarian cancer | GYNECOLOGIC-ONCOLOGY-GROUP | STAGE-III | CHEMOTHERAPY | PACLITAXEL | OBSTETRICS & GYNECOLOGY | TRIAL | WOMEN | CISPLATIN | ONCOLOGY | Neoplasm Recurrence, Local - economics | United States | Humans | Neoplasm Recurrence, Local - drug therapy | Piperazines - economics | Phthalazines - economics | Antineoplastic Agents - therapeutic use | Models, Economic | Ovarian Neoplasms - genetics | Maintenance Chemotherapy - methods | Antineoplastic Combined Chemotherapy Protocols - economics | Genes, BRCA2 | Germ-Line Mutation | Female | Genes, BRCA1 | Paclitaxel - administration & dosage | Ovarian Neoplasms - drug therapy | Paclitaxel - economics | Decision Support Techniques | Carboplatin - administration & dosage | Piperazines - therapeutic use | Carboplatin - economics | Antineoplastic Agents - economics | Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use | Disease-Free Survival | Poly(ADP-ribose) Polymerase Inhibitors - economics | Phthalazines - therapeutic use | Ovarian Neoplasms - economics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cost-Benefit Analysis | Maintenance Chemotherapy - economics | Neoplasm Recurrence, Local - genetics | Relapse | Cost benefit analysis | Analysis | Diseases | Index Medicus
Journal Article
Journal Article
Journal Article
International Journal of Radiation Biology, ISSN 0955-3002, 01/2018, Volume 94, Issue 1, pp. 45 - 53
Journal Article
Journal of the Taiwan Institute of Chemical Engineers, ISSN 1876-1070, 03/2015, Volume 48, pp. 1 - 7
In this study, we suggest a workflow for the identification of potential leads targeted against poly(ADP-ribose) polymerase (PARP). To clarify the essential... 
Poly(ADP-ribose) polymerase-1 | Virtual screening | Pharmacophore modeling | Anticancer | Molecular docking | CELLS | APOPTOSIS | DNA-DAMAGE | DEPICTION | IDENTIFICATION | CANCER | ENGINEERING, CHEMICAL | POTENT | ONCOLOGY | DISEASE | PARP INHIBITORS
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 2019, Volume 141, Issue 13, pp. 5169 - 5181
DNA-encoded chemical libraries are increasingly used in pharmaceutical research because they enable the rapid discovery of synthetic protein ligands. Here we... 
CANCER-CELLS | POLY(ADP-RIBOSE) POLYMERASE PARP | DESIGN | ADP-RIBOSYLTRANSFERASES | PROTEIN | LIGANDS | DEACETYLASE SIRT6 | HIGHLY POTENT | SELECTION | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal Article
Experimental Neurology, ISSN 0014-4886, 05/2009, Volume 217, Issue 1, pp. 210 - 218
It is increasingly recognized that histological and functional outcomes after stroke are shaped by biologic sex. Emerging data suggests that ischemic cell... 
Stroke | Poly (ADP-ribose) polymerase 1 (PARP1) | Poly (ADP-ribose) polymers (PAR) | Middle cerebral artery occlusion | Sex | Estrogen | Apoptosis inducing factor (AIF) | APOPTOSIS-INDUCING FACTOR | POLY(ADP-RIBOSE) POLYMERASE | NITRIC-OXIDE SYNTHASE | FOCAL CEREBRAL-ISCHEMIA | NEUROSCIENCES | OXYGEN-GLUCOSE DEPRIVATION | CELL-DEATH | 2 DISTINCT PATHWAYS | PERINATAL BRAIN-INJURY | NEURONAL DEATH | ESTROGEN PLUS PROGESTIN | Enzyme-Linked Immunosorbent Assay - methods | Estradiol - blood | Stroke - complications | Male | Protein Transport - physiology | Sex Differentiation | Subcellular Fractions - pathology | Stroke - genetics | Poly Adenosine Diphosphate Ribose - genetics | Stroke - pathology | Reperfusion | Time Factors | Mice, Mutant Strains | Female | Apoptosis Inducing Factor - metabolism | Disease Models, Animal | Estradiol - administration & dosage | Ovariectomy - methods | Brain Infarction - physiopathology | Subcellular Fractions - metabolism | Mice, Knockout | Brain Infarction - etiology | Poly Adenosine Diphosphate Ribose - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Stroke - metabolism | Animals | Analysis of Variance | Nervous System Diseases - etiology | Poly(ADP-ribose) Polymerases - deficiency | Mice | Poly (ADP-Ribose) Polymerase-1 | Nitric Oxide - metabolism | Brain Infarction - genetics | Stroke (Disease) | Brain | Neurosciences | Neurons | Cell death | Nitric oxide | Injuries | Index Medicus | Apoptosis Inducing Factor (AIF) | Middle Cerebral Artery Occlusion | Poly (ADP-ribose) Polymers (PAR) | Poly (ADP-ribose) Polymerase 1 (PARP1)
Journal Article
Journal Article
Histopathology, ISSN 0309-0167, 12/2012, Volume 61, Issue 6, pp. 1089 - 1105
Mascolo M, Ilardi G, Romano M F, Celetti A, Siano M, Romano S, Luise C, Merolla F, Rocco A, Vecchione M L, De Rosa G & Staibano S 
(2012) Histopathology 
... 
PARP‐1 | stem cells | prognosis | CAF‐1 p60 | oral cancer | CAF-1 p60 | Prognosis | Oral cancer | PARP-1 | Stem cells | HEAD | PROTEIN | BIOLOGICAL BEHAVIOR | PROLIFERATION | HUMAN-PAPILLOMAVIRUS | PATHOLOGY | DNA-REPLICATION | CELL BIOLOGY | STEM-LIKE CELLS | SQUAMOUS-CELL CARCINOMA | CLINICAL-VALUE | EXPRESSION | Predictive Value of Tests | Up-Regulation | Nestin | Follow-Up Studies | Carcinoma, Squamous Cell - metabolism | Humans | Middle Aged | Male | Mouth Neoplasms - metabolism | Chromatin Assembly Factor-1 - metabolism | Carcinoma, Squamous Cell - diagnosis | Mouth Neoplasms - diagnosis | Carcinoma, Squamous Cell - mortality | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Survival Rate | Mouth Neoplasms - mortality | Disease Progression | Nerve Tissue Proteins - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Neoplasm Metastasis - diagnosis | Aged | Intermediate Filament Proteins - metabolism | Immunohistochemistry | Medical colleges | Squamous cell carcinoma | Chromatin | RNA | Analysis | Metastasis | Tumor proteins | Intermediate filament proteins | Papillomavirus infections | Mouth cancer | Human papillomavirus | Rodents | Cancer | Index Medicus | poly(ADP-ribose) polymerase 1 | Tongue | Cell survival | RNA-mediated interference | Data processing | Population studies | Radioresistance | oral squamous cell carcinoma | Multivariate analysis | Western blotting | Chromatin remodeling | Cleft lip/palate | Metastases | CD44 antigen | Surgery | Palate | Original
Journal Article
Nature medicine, ISSN 1078-8956, 2017, Volume 23, Issue 4, pp. 517 - 525
Journal Article