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polymerase (17) 17
reactive oxygen species - metabolism (17) 17
biochemistry (16) 16
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mutation (16) 16
plant extracts - pharmacology (16) 16
poly polymerase 1 (16) 16
tumors (16) 16
adp (15) 15
cell proliferation - drug effects (15) 15
cytochromes c - metabolism (15) 15
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mitochondria - drug effects (15) 15
nutrition & dietetics (15) 15
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phosphorylation (15) 15
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Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e22447
Background: Although enzyme replacement therapy (ERT) is available for several lysosomal storage disorders, the benefit of this treatment to the skeletal... 
MECHANISM | GENE | MULTIDISCIPLINARY SCIENCES | ARYLSULFATASE-B | JOINT DISEASE | BONE | IDENTIFICATION | Bone and Bones - pathology | Chondrocytes - pathology | Enzyme Replacement Therapy | Anti-Inflammatory Agents - pharmacology | Humans | Mucopolysaccharidosis VI - pathology | Motor Activity - drug effects | Rats | Trachea - drug effects | Bone and Bones - drug effects | Mucopolysaccharidosis VI - therapy | Trachea - pathology | Cartilage, Articular - pathology | Chondrocytes - drug effects | Gait - drug effects | Animals | Anti-Inflammatory Agents - therapeutic use | Cartilage, Articular - drug effects | Mucopolysaccharidosis VI - physiopathology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Trachea - abnormalities | Enzymes | Medical research | Tumor necrosis factor | Collagen | Medicine, Experimental | Mucopolysaccharidosis | Gene therapy | Health aspects | Biopharmaceutics | Therapy | Animal models | Deformation | Motor activity | Disorders | N-acetyl-galactosamine | Clinical trials | Lysosomal storage diseases | Systematic review | Cartilage | Angiogenesis | Bone growth | Computed tomography | Rodents | Computer architecture | Toll-like receptors | Ceramide | Bones | Bioindicators | TRANCE protein | Trachea | Recombinant | Cytokines | Poly(ADP-ribose) polymerase | Cystic fibrosis | Inflammation | Cartilage (articular) | TLR4 protein | Tumor necrosis factor-α | Crohns disease | Medicine | Serum levels | Rheumatoid arthritis | Chondrocytes | Biomarkers | Skeletal system | Combined treatment | Bone | Apoptosis
Journal Article
The Prostate, ISSN 0270-4137, 09/2019, Volume 79, Issue 12, pp. 1471 - 1486
Background The 25th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held in Carlsbad, CA, from 26 to 28 October 2018. Methods The PCF Scientific... 
diagnosis | tumor biology | androgen receptor | prognosis | therapy | ENDOCRINOLOGY & METABOLISM | UROLOGY & NEPHROLOGY | Prostate cancer | Signal transduction | Medical research | Wnt protein | Ribose | Immunotherapy | Stem cells | Poly(ADP-ribose) polymerase | Nervous system | Biology
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 2009, Volume 47, Issue 8, pp. 2013 - 2021
The MDM2 proto-oncogene is overexpressed in many human tumors. Although MDM2 inhibits tumor-suppressor function of p53, there exists a p53-independent role for... 
MDM2 | Ubiquitination | Hispolon | p21 | p53 | APOPTOSIS | PROTEIN | RAS | FOOD SCIENCE & TECHNOLOGY | DNA-DAMAGE | ANTISENSE THERAPY | PROLIFERATION | PATHWAY | P53 ACTIVATION | GENE-EXPRESSION | TOXICOLOGY | MDM2 ONCOGENE | Proto-Oncogene Proteins c-mdm2 - genetics | Immunoprecipitation | Caspase 7 - biosynthesis | Apoptosis - drug effects | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Urinary Bladder Neoplasms - enzymology | Proto-Oncogene Proteins c-mdm2 - physiology | Catechols - isolation & purification | Mitogen-Activated Protein Kinase 1 - chemistry | Breast Neoplasms - enzymology | Flow Cytometry | Antibiotics, Antineoplastic - chemistry | Urinary Bladder Neoplasms - pathology | Catechols - pharmacology | Female | Mitogen-Activated Protein Kinase 3 - chemistry | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Tumor Suppressor Protein p53 - metabolism | Enzyme Induction | Urinary Bladder Neoplasms - drug therapy | Cell Nucleus - ultrastructure | Breast Neoplasms - drug therapy | Poly(ADP-ribose) Polymerases - metabolism | Breast Neoplasms - pathology | Cell Line, Tumor | Indicators and Reagents | Cell Cycle - drug effects | Cell Nucleus - drug effects | Agaricales - chemistry | Ubiquitin | Phosphates | Medical colleges | Phosphatidylinositol | Ligases | Pharmacy | Breast cancer | Automated teller machines | Tumor proteins | Bladder cancer
Journal Article
Archives of Pharmacal Research, ISSN 0253-6269, 8/2011, Volume 34, Issue 8, pp. 1363 - 1372
Journal Article
Kaohsiung Journal of Medical Sciences, ISSN 1607-551X, 10/2017, Volume 33, Issue 10, pp. 486 - 495
Rheumatoid arthritis is a common autoimmune disease, however, available regimes exert little influence on it's long-term prognosis. The aim of the current... 
Securidaca inappendiculata | Fibroblast-like synoviocytes | Xanthones | Rheumatoid arthritis | p65 | Fibroblast‐like synoviocytes | RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | ACTIVATION | ADJUVANT-INDUCED ARTHRITIS | SECURIDACA-INAPPENDICULATA | PATHOGENESIS | DICHLOROMETHANE FRACTION | Fibroblast-like | INFLAMMATION | DISEASE | synoviocytes | Apoptosis - drug effects | Humans | NF-KappaB Inhibitor alpha - genetics | NF-kappa B - metabolism | Xanthones - pharmacology | Transcription Factor RelA - genetics | Pyrrolidines - pharmacology | Synoviocytes - drug effects | Arthritis, Rheumatoid - metabolism | Synoviocytes - metabolism | Thiocarbamates - pharmacology | I-kappa B Kinase - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Antirheumatic Agents - pharmacology | Cell Line | Signal Transduction | Gene Expression Regulation | p38 Mitogen-Activated Protein Kinases - genetics | I-kappa B Kinase - genetics | X-Linked Inhibitor of Apoptosis Protein - genetics | Arthritis, Rheumatoid - pathology | Arthritis, Rheumatoid - genetics | Poly(ADP-ribose) Polymerases - metabolism | Poly(ADP-ribose) Polymerases - genetics | NF-kappa B - genetics | Transcription Factor RelA - metabolism | NF-KappaB Inhibitor alpha - metabolism | Synoviocytes - pathology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Cell Proliferation - drug effects
Journal Article
Physiological Reviews, ISSN 0031-9333, 01/2007, Volume 87, Issue 1, pp. 315 - 424
Journal Article