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The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 06/2015, Volume 353, Issue 3, pp. 446 - 457
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 28, pp. 10209 - 10214
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 5, pp. 664 - 678
Recurrent fusions of ETS genes are considered driving mutations in a diverse array of cancers, including Ewing's sarcoma, acute myeloid leukemia, and prostate... 
TRANSCRIPTION FACTORS | ANDROGEN RECEPTOR | EWS GENE | ONCOLOGY | TMPRSS2-ERG FUSION | EWINGS-SARCOMA TRANSLOCATION | DNA-LIGASE IV | ERG | EXPRESSION | TUMORS | PROGRESSION | CELL BIOLOGY | Oncogene Proteins, Fusion - metabolism | Humans | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Male | Recombinant Fusion Proteins - metabolism | Oncogene Proteins, Fusion - chemistry | Prostatic Neoplasms - genetics | Transfection | Chromatin Immunoprecipitation | RNA Interference | Time Factors | DNA-Activated Protein Kinase - metabolism | Mass Spectrometry | HEK293 Cells | Antineoplastic Agents - pharmacology | Genes, Reporter | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - pathology | Catalytic Domain | Neoplasm Invasiveness | Enzyme Inhibitors - pharmacology | Models, Molecular | Gene Fusion | Tumor Burden | Mice, SCID | Chick Embryo | Piperazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors | Xenograft Model Antitumor Assays | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | Mice, Nude | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Protein Conformation | Mice | Mice, Inbred BALB C | DNA Damage | Poly (ADP-Ribose) Polymerase-1 | Cell Movement | Enzymes | Sarcoma | Leukemia | DNA | Genetic aspects | Prostate cancer | Protein kinases | Cancer | Index Medicus | DNA-PKcs | PARP1 | TMPRSS2 | Prostate | Rearrangement
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 43, pp. 18475 - 18480
Many proteins that respond to DNA damage are recruited to DNA lesions. We used a proteomics approach that coupled isotopic labeling with chromatin... 
Chromatin | Ultraviolet lasers | RNA | DNA damage | DNA | Stem cells | HeLa cells | Histones | Antibodies | Lesions | Damage signaling | MEL-18 | Polycomb repressive complex 1 | Polycomb repressive complex 2 | B lymphoma Mo-MLV insertion region 1 homolog (BMI1) | MONOUBIQUITINATED FANCD2 | MULTIDISCIPLINARY SCIENCES | damage signaling | polycomb repressive complex 1 | polycomb repressive complex 2 | DOUBLE-STRAND BREAKS | BRCA1 | IDENTIFICATION | REPAIR PROTEINS | CAENORHABDITIS-ELEGANS | GENE | PATHWAY | ATM | CELL | Chromatin - metabolism | Caenorhabditis elegans - metabolism | Humans | Mi-2 Nucleosome Remodeling and Deacetylase Complex - metabolism | Polycomb-Group Proteins | Caenorhabditis elegans - radiation effects | Ultraviolet Rays - adverse effects | Poly Adenosine Diphosphate Ribose - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Chromatin - radiation effects | DNA Repair | Proteomics | DNA Damage | HeLa Cells | In Vitro Techniques | Repressor Proteins - metabolism | Development and progression | Lymphomas | Cellular signal transduction | Genetic aspects | Research | Properties | Proteins | Mammals | DNA repair | Mass spectrometry | Cells | Binding sites | Index Medicus | Histone deacetylase | Transcription | proteomics | NuRD protein | Poly(ADP-ribose) polymerase | Mass spectroscopy | polycomb group proteins | DNA-directed RNA polymerase | Mammalian cells | Metastases | DNA helicase | Nucleoli | DNA-binding protein | Lasers | Ribose | Nucleosomes | Biological Sciences
Journal Article
Journal Article
Nature, ISSN 0028-0836, 09/2011, Volume 477, Issue 7366, pp. 616 - 622
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 7, pp. 2783 - 2788
Journal Article
Nature, ISSN 0028-0836, 04/2005, Volume 434, Issue 7035, pp. 913 - 917
Journal Article