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Immunity (Cambridge, Mass.), ISSN 1074-7613, 04/2017, Volume 46, Issue 4, pp. 596 - 608
... at both pro-memory and pro-effector genes in MP cells, indicative of multipotency. Polycomb repressive complex 2 deficiency impaired clonal expansion and TE cell differentiation, but minimally impacted CD8+ memory T cell maturation... 
PRC2 | Polycomb repressive complex 2 | CD8+ T cell differentiation | H3K27ac | plasticity | terminal differentiation | epigenetics | FOXO1 | H3K27me3 | EZH2 | T cell differentiation | CD8 | BET | IDENTITY | DNA METHYLATION | MEMORY | H3 LYSINE 27 | IMMUNOLOGY | TRANSCRIPTION FACTOR | EXPRESSION | VIRAL-INFECTION | DIVISION | Chromatin - metabolism | Polycomb Repressive Complex 2 - genetics | Multipotent Stem Cells - metabolism | Immunoblotting | Multipotent Stem Cells - immunology | Cell Differentiation - genetics | Flow Cytometry | Forkhead Box Protein O1 - immunology | Chromatin - immunology | Gene Expression - immunology | Polycomb Repressive Complex 2 - immunology | CD8-Positive T-Lymphocytes - metabolism | Lysine - metabolism | Immunologic Memory - genetics | Immunologic Memory - immunology | Forkhead Box Protein O1 - metabolism | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Histones - immunology | Mice, Inbred C57BL | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Cell Differentiation - immunology | Models, Immunological | Animals | Enhancer of Zeste Homolog 2 Protein - immunology | Histones - metabolism | CD8-Positive T-Lymphocytes - immunology | Methylation | Polycomb Repressive Complex 2 - metabolism | Chromatin - genetics | Forkhead Box Protein O1 - genetics | Lysine - immunology | Chromatin | Transcription factors | Profiling | CD8 antigen | Genes | Developmental plasticity | Differentiation (biology) | Effector cells | Cytotoxicity | Infections | Lymphocytes T | Genomes | Immunity | Immunology | FOXO1 protein | Lymphocytes | DNA methylation | Deposition | Antigens | Immunological memory | Memory cells | Cell survival | Cytokines | Maturation | Cell division | T cell receptors | Longevity | Cell differentiation | Gene expression | Survival | Polycomb group proteins | Gene silencing | Stem cells | Epigenetics | Viral infections | CD8+ T cell differentiation
Journal Article
Journal Article
Journal Article
Nature medicine, ISSN 1546-170X, 2012, Volume 18, Issue 2, pp. 298 - 302
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2012, Volume 109, Issue 13, pp. 5028 - 5033
.... Polycomb repressive complex 2 (PRC2) has been implicated in self-renewal and cancer progression, and its components are overexpressed in many cancers... 
Lymphocytes | Myeloid leukemia | Leukemia | Stem cells | Genetic loci | Mice | Null set | Embryonic stem cells | Pluripotent stem cells | Cells | Epigenetics | Polycomb group proteins | Mouse model | Myeloid-lymphoid leukemia protein | H3K79 METHYLATION | DEVELOPMENTAL REGULATORS | mouse model | MULTIDISCIPLINARY SCIENCES | METHYLTRANSFERASE GENE EZH2 | TRANSCRIPTION | PLURIPOTENCY | polycomb group proteins | CANCER | epigenetics | MAINTENANCE | MYC | EMBRYONIC STEM-CELLS | MYELOID-LEUKEMIA | myeloid-lymphoid leukemia protein | Oncogene Proteins, Fusion - metabolism | Cell Proliferation | Leukemia - pathology | Genetic Loci - genetics | Genome - genetics | Gene Expression Profiling | Histone-Lysine N-Methyltransferase - deficiency | Chromatin Immunoprecipitation | Precancerous Conditions - pathology | Genes, Neoplasm - genetics | Leukemia - genetics | Repressor Proteins - metabolism | Cytoprotection | Mice, Inbred C57BL | Gene Silencing | Gene Expression Regulation, Leukemic | Polycomb-Group Proteins | Precancerous Conditions - genetics | Proto-Oncogene Proteins c-myc - metabolism | Disease Progression | Down-Regulation - genetics | Enhancer of Zeste Homolog 2 Protein | Phenotype | Polycomb Repressive Complex 2 | Animals | Histone-Lysine N-Methyltransferase - metabolism | Histones - metabolism | Methylation | Proteins | Epigenetic inheritance | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Health aspects | Cancer | Biological Sciences
Journal Article
eLife, ISSN 2050-084X, 2012, Volume 1, Issue 1, p. e00005
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 11/2010, Volume 107, Issue 45, pp. 19266 - 19271
Journal Article