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Journal Article
Journal Article
Archives of toxicology, ISSN 1432-0738, 11/2014, Volume 90, Issue 2, pp. 291 - 304
.... We have investigated the role of TP53 in cytochrome P450 (CYP)-mediated metabolic activation of three polycyclic aromatic hydrocarbons (PAHs... 
Benzo[ a ]pyrene | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Cytochrome P450 | Carcinogen metabolism | DNA adducts | Pharmacology/Toxicology | Tumour suppressor p53 | Biomedicine general | Benzo[a]pyrene | Life Sciences & Biomedicine | Toxicology | Science & Technology | DNA Damage - drug effects | Cell Survival - drug effects | Cytochrome P-450 CYP1B1 - genetics | Inactivation, Metabolic | Polycyclic Aromatic Hydrocarbons - pharmacokinetics | Benzo(a)pyrene - toxicity | Polycyclic Aromatic Hydrocarbons - toxicity | Humans | Tumor Suppressor Protein p53 - metabolism | Cytochrome P-450 CYP1B1 - metabolism | NAD(P)H Dehydrogenase (Quinone) - genetics | Cytochrome P-450 CYP1A1 - metabolism | HCT116 Cells - drug effects | Tumor Suppressor Protein p53 - genetics | Carcinogens - toxicity | DNA Adducts | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cytochrome P-450 Enzyme Inducers - poisoning | DNA Damage - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Receptors, Aryl Hydrocarbon - metabolism | Cytochrome P-450 Enzyme Inducers - pharmacology | Toxicity Tests | Cytochrome P-450 Enzyme Inducers - toxicity | Metabolites | Benzopyrene | Analysis | Cytochrome P-450 | Physiological aspects | Tumor proteins | Xenobiotics | Cells | Cytochrome | Carcinogens | Polycyclic aromatic hydrocarbons | Tumors | Index Medicus | Toxicokinetics and Metabolism | Cell Survival | HCT116 Cells | Polycyclic Aromatic Hydrocarbons | Benzo(a)pyrene | NAD(P)H Dehydrogenase (Quinone) | Journal Article | Cytochrome P-450 Enzyme Inducers | Tumor Suppressor Protein p53 | Research Support, Non-U.S. Gov't | Cytochrome P-450 CYP1B1 | Cytochrome P-450 CYP1A1 | DNA Damage | Receptors, Aryl Hydrocarbon | Basic Helix-Loop-Helix Transcription Factors
Journal Article
Drug metabolism and disposition, ISSN 1521-009X, 03/2020, Volume 48, Issue 3, pp. 160 - 168
Polycyclic aromatic hydrocarbons (PAHs) are potent carcinogens and are a primary risk factor for the development of lung and other aerodigestive tract cancers in smokers... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | N-Acetylglucosamine | Glycosyltransferase | Detoxification | Glycosylation | Glucose | Tissues | Metabolism | Risk analysis | Risk factors | Microsomes | Xylose | Carcinogens | Polycyclic aromatic hydrocarbons | Smoking | Index Medicus
Journal Article
Journal Article