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1. Full Text Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management—A KDIGO consensus report
by Eckardt, Kai-Uwe and Alper, Seth L and Antignac, Corinne and Bleyer, Anthony J and Chauveau, Dominique and Dahan, Karin and Deltas, Constantinos and Hosking, Andrew and Kmoch, Stanislav and Rampoldi, Luca and Wiesener, Michael and Wolf, Matthias T and Devuyst, Olivier and Kidney Disease: Improving Global Outcomes
Kidney International, ISSN 0085-2538, 10/2015, Volume 88, Issue 4, pp. 676 - 683
Rare autosomal dominant tubulointerstitial kidney disease is caused by mutations in the genes encoding uromodulin (UMOD), hepatocyte nuclear factor-1 beta... 
kidney disease | uromodulin | hepatocyte nuclear factor-1β | genetics | mucin-1 | renin | UMOD GENE | TAMM-HORSFALL PROTEIN | RENAL-DISEASE | JUVENILE HYPERURICEMIC NEPHROPATHY | HEPATOCYTE NUCLEAR FACTOR-1-BETA | HYPERTENSIVE PATIENTS | CELL CARCINOMA | SERUM URIC-ACID | MEDULLARY CYSTIC-DISEASE | UROLOGY & NEPHROLOGY | hepatocyte nuclear factor-1 beta | Predictive Value of Tests | Humans | Kidney Diseases - diagnosis | Polycystic Kidney, Autosomal Dominant - therapy | Gout - diagnosis | Nephrology - standards | Kidney Diseases - genetics | Uromodulin - classification | Uromodulin - deficiency | Polycystic Kidney, Autosomal Dominant - genetics | DNA Mutational Analysis | Hyperuricemia - therapy | Uromodulin - genetics | Genetic Predisposition to Disease | Kidney Diseases - classification | Hyperuricemia - diagnosis | Hyperuricemia - classification | Terminology as Topic | Treatment Outcome | Consensus | Hyperuricemia - genetics | Gout - therapy | Phenotype | Polycystic Kidney, Autosomal Dominant - diagnosis | Kidney Diseases - therapy | Gout - classification | Gout - genetics | Polycystic Kidney, Autosomal Dominant - classification | Mutation
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2. Full Text Renal replacement therapy for autosomal dominant polycystic kidney disease (ADPKD) in Europe: prevalence and survival--an analysis of data from the ERA-EDTA Registry
by Spithoven, Edwin M and Kramer, Anneke and Meijer, Esther and Orskov, Bjarne and Wanner, Christoph and Abad, Jose M and Aresté, Nuria and de la Torre, Ramón Alonso and Caskey, Fergus and Couchoud, Cécile and Finne, Patrik and Heaf, James and Hoitsma, Anies and de Meester, Johan and Pascual, Julio and Postorino, Maurizio and Ravani, Pietro and Zurriaga, Oscar and Jager, Kitty J and Gansevoort, Ron T and de Los Ángeles García Bazaga, M and Metcalfe, W and Roigo, E and Quirós, J. R and Budde, K and Chauveau, D and Devuyst, O and Ecder, T and Eckardt, K. U and Gansevoort, R. T and Köttgen, A and Ong, A. C and Petzold, K and Pirson, Y and Remuzzi, G and Torra, R and Sandford, R. N and Serra, A. L and Tesar, V and Walz, G and Wüthrich, R. P and Antignac, C and Bindels, R and Emma, F and Maxwell, P. H and Ronco, P and Schaefer, F and ERA-EDTA Registry and EuroCYST Consortium and WGIKD and on behalf of the ERA-EDTA Registry
Nephrology, dialysis, transplantation, ISSN 0931-0509, 2014, Volume 29, Issue Suppl. 4, pp. iv15 - iv25
Autosomal dominant polycystic kidney disease (ADPKD) is the fourth most common renal disease requiring renal replacement therapy (RRT). Still, there are few... 
ADPKD | Prevalence | Renal replacement therapy | Epidemiology | Survival | MORTALITY | renal replacement therapy | MULTICENTER | COST-ANALYSIS | PROGNOSIS | survival | PERITONEAL-DIALYSIS | TRANSPLANTATION | TRIAL | epidemiology | prevalence | UROLOGY & NEPHROLOGY | COMPLICATIONS | Humans | Middle Aged | Polycystic Kidney, Autosomal Dominant - therapy | Europe - epidemiology | Male | Survival Rate | Renal Replacement Therapy - mortality | Polycystic Kidney, Autosomal Dominant - mortality | Renal Dialysis - mortality | Time Factors | Registries - statistics & numerical data | Female | Aged | Index Medicus
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3. Full Text Autosomal dominant polycystic kidney disease: the changing face of clinical management
by Ong, Albert C M, Prof and Devuyst, Olivier, Prof and Knebelmann, Bertrand, Prof and Walz, Gerd, Prof and ERA-EDTA Working Grp Inherited Kid and ERA-EDTA Working Group for Inherited Kidney Diseases
The Lancet, ISSN 0140-6736, 2015, Volume 385, Issue 9981, pp. 1993 - 2002
Summary Autosomal dominant polycystic kidney disease is the most common inherited kidney disease and accounts for 7–10% of all patients on renal replacement... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | ADPKD | GENE | VOLUME | RENAL-FUNCTION | RECEPTOR | LEFT-VENTRICULAR MASS | MUTATIONS | CYST GROWTH | PROGRESSION | PRIMARY CILIA | Genetic Testing | Prognosis | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Polycystic Kidney, Autosomal Dominant - therapy | Protein-Serine-Threonine Kinases - genetics | Male | Mutation - genetics | Forecasting | TRPP Cation Channels - genetics | Young Adult | Polycystic Kidney, Autosomal Dominant - diagnosis | Adolescent | Polycystic Kidney, Autosomal Dominant - etiology | Adult | Female | Signal Transduction - physiology | Aged | Child | Cyclic AMP - metabolism | Medical colleges | Development and progression | Polycystic kidney disease | Studies | Kidney diseases | Disease management | Epidemiology | Patients
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4. Full Text Autosomal dominant polycystic kidney disease: the last 3 years
by Torres, Vicente E and Harris, Peter C
Kidney International, ISSN 0085-2538, 07/2009, Volume 76, Issue 2, pp. 149 - 168
Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal monogenic disorder. It has large inter- and intra-familial variability... 
polycystin-2 | polycystin-1 | ADPKD | PKD2 | polycystic kidney disease | PKD1 | Polycystin-2 | Polycystin-1 | Polycystic kidney disease | RENAL EPITHELIAL-CELLS | ENDOTHELIAL DYSFUNCTION | LIVER CYST | PROMOTER POLYMORPHISM | HAN-SPRD RATS | MOLECULAR DIAGNOSTICS | CONVERTING ENZYME-INHIBITION | CYST FORMATION | UROLOGY & NEPHROLOGY | HEPATIC CYSTOGENESIS | ENDOPLASMIC-RETICULUM | Genetic Variation | Polycystic Kidney, Autosomal Dominant - genetics | Humans | Polycystic Kidney, Autosomal Dominant - therapy | Polycystic Kidney, Autosomal Dominant - pathology | Female | Male | TRPP Cation Channels - genetics
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5. Full Text Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
by Chapman, Arlene B and Devuyst, Olivier and Eckardt, Kai-Uwe and Gansevoort, Ron T and Harris, Tess and Horie, Shigeo and Kasiske, Bertram L and Odland, Dwight and Pei, York and Perrone, Ronald D and Pirson, Yves and Schrier, Robert W and Torra, Roser and Torres, Vicente E and Watnick, Terry and Wheeler, David C and Conference Participants
Kidney International, ISSN 0085-2538, 07/2015, Volume 88, Issue 1, pp. 17 - 27
Autosomal-dominant polycystic kidney disease (ADPKD) affects up to 12 million individuals and is the fourth most common cause for renal replacement therapy... 
diagnosis | ADPKD | patient support | end-stage renal disease | management | polycystic kidney disease | End-stage renal disease | Diagnosis | Management | Patient support | Polycystic kidney disease | FOLLOW-UP | LIVER-DISEASE | NATIVE NEPHRECTOMY | PREIMPLANTATION GENETIC DIAGNOSIS | UNRUPTURED INTRACRANIAL ANEURYSMS | UROLOGY & NEPHROLOGY | CYST INFECTION | LONG-ACTING SOMATOSTATIN | LEFT-VENTRICULAR MASS | QUALITY-OF-LIFE | RENAL REPLACEMENT THERAPY | Humans | Polycystic Kidney, Autosomal Dominant - therapy | Consensus | Disease Progression | Kidney Failure, Chronic - therapy | Kidney Failure, Chronic - prevention & control | Polycystic Kidney, Autosomal Dominant - diagnosis | Hypertension - complications | Polycystic Kidney, Autosomal Dominant - physiopathology | Hypertension - therapy | Hypertension - diagnosis | Polycystic Kidney, Autosomal Dominant - complications | Kidney Failure, Chronic - etiology
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6. Targeted Therapies for Autosomal Dominant Polycystic Kidney Disease
by Stayner, C and Brooke, DG and Bates, M and Eccles, MR
CURRENT MEDICINAL CHEMISTRY, ISSN 0929-8673, 2019, Volume 26, Issue 17, pp. 3081 - 3102
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common life-threatening genetic disease in humans, affecting approximately 1 in... 
CANCER-CELLS | CHEMISTRY, MEDICINAL | RENAL CYSTS | targeted therapies | DRUG-DELIVERY | HEPATIC CYSTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | kidney disease | PKD1 REGION | LIVER-DISEASE | BLOOD-PRESSURE | autosomal disease | ADPKD | kidney-specific therapy | SOMATOSTATIN ANALOG | INHIBITION | polycystic kidney disease | Autosomal dominant polycystic kidney disease | PHARMACOLOGY & PHARMACY | PROGRESSION | End-stage renal disease | Regulatory agencies | Animal models | Kidneys | Calcium | Toxicity | Hemodialysis | Polycystic kidney | Medical services | Feasibility studies | Clinical trials | Polycystic kidney disease 1 protein | Transplantation | FDA approval | Patients | Polycystin-2 | Dialysis | Kidney diseases | Calcium ions | Kidney transplantation
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7. Full Text Autosomal Dominant Polycystic Kidney Disease: Core Curriculum 2016
by Chebib, Fouad T., MD and Torres, Vicente E., MD, PhD
American Journal of Kidney Diseases, ISSN 0272-6386, 2015, Volume 67, Issue 5, pp. 792 - 810
Nephrology | PREIMPLANTATION GENETIC DIAGNOSIS | TREATMENT OPTIONS | ADPKD | MANAGEMENT | ANEURYSMS | VOLUME | UROLOGY & NEPHROLOGY | CYST INFECTION | OUTCOMES | LIVER-DISEASE | RENAL REPLACEMENT THERAPY | Nephrolithiasis - etiology | Nephrolithiasis - therapy | Polycystic Kidney, Autosomal Dominant - epidemiology | Kidney - pathology | Humans | Polycystic Kidney, Autosomal Dominant - therapy | Hypertension - drug therapy | Kidney Transplantation | Antihypertensive Agents - therapeutic use | Genetic Counseling | TRPP Cation Channels - genetics | Urinary Tract Infections - drug therapy | Hypertension - etiology | Kidney Failure, Chronic - therapy | Radiography | Kidney - diagnostic imaging | Polycystic Kidney, Autosomal Dominant - diagnosis | Urinary Tract Infections - etiology | Disease Management | Polycystic Kidney, Autosomal Dominant - complications | Kidney Failure, Chronic - etiology | Renal Dialysis
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8. Full Text Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease
by Torres, Vicente E and Chapman, Arlene B and Devuyst, Olivier and Gansevoort, Ron T and Grantham, Jared J and Higashihara, Eiji and Perrone, Ronald D and Krasa, Holly B and Ouyang, John and Czerwiec, Frank S and TEMPO 3 4 Trial Investigators
The New England Journal of Medicine, ISSN 0028-4793, 12/2012, Volume 367, Issue 25, pp. 2407 - 2418
In this trial, patients with autosomal dominant polycystic kidney disease were randomly assigned to tolvaptan, a vasopressin V 2 -receptor antagonist, or... 
MEDICINE, GENERAL & INTERNAL | VOLUME PROGRESSION | VASOPRESSIN V-2-RECEPTOR ANTAGONIST | ORAL TOLVAPTAN | HYPONATREMIA | RENAL-FUNCTION | OPC-41061 | LONG-ACTING SOMATOSTATIN | V2 RECEPTOR ANTAGONIST | CYST GROWTH | SIROLIMUS | Drugs | Dose-response relationship (Biochemistry) | Product/Service Evaluations | Drug therapy | Polycystic kidney disease | Studies | Nuclear magnetic resonance--NMR | Kidney diseases | Cysts | Rodents | Index Medicus | Abridged Index Medicus
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9. Full Text Molecular pathways and therapies in autosomal-dominant polycystic kidney disease
by Saigusa, Takamitsu and Darwin Bell, P
Physiology, ISSN 1548-9213, 2015, Volume 30, Issue 3, pp. 195 - 207
Autosomal-dominant polycystic kidney disease (ADPKD) is the most prevalent inherited renal disease, characterized by multiple cysts that can eventually lead to... 
CONDITIONAL INACTIVATION | PHYSIOLOGY | COLLECTING DUCT CELLS | RENIN-ANGIOTENSIN SYSTEM | SIGNALING PATHWAY | CYST EPITHELIAL-CELLS | CFTR INHIBITORS | PLANAR CELL POLARITY | RENAL-DISEASE | LIVER-DISEASE | BETA-CATENIN | Polycystic Kidney, Autosomal Dominant - epidemiology | Predictive Value of Tests | Genetic Predisposition to Disease | Genetic Testing | Kidney - drug effects | Kidney - pathology | Signal Transduction | Humans | Polycystic Kidney, Autosomal Dominant - therapy | Risk Factors | Treatment Outcome | Molecular Targeted Therapy | TRPP Cation Channels - genetics | Polycystic Kidney, Autosomal Dominant - metabolism | Kidney - metabolism | Phenotype | Animals | Polycystic Kidney, Autosomal Dominant - genetics | Polycystic Kidney, Autosomal Dominant - diagnosis | Mutation | Cilia | Reviews
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