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Kidney International, ISSN 0085-2538, 05/2013, Volume 83, Issue 5, pp. 855 - 864
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, p. e0177934
Increased intracellular cyclic AMP (cAMP) in renal tubular epithelia accelerates the progression of polycystic kidney disease (PKD). Thus, decreasing cAMP... 
SOM230 | SOMATOSTATIN ANALOGS | ACTIVATION | INHIBITION | CYSTOGENESIS | MULTIDISCIPLINARY SCIENCES | GROWTH | KINASE | CONGENITAL HEPATIC-FIBROSIS | LIVER-DISEASE | PROGRESSION | Liver - pathology | Kidney - pathology | Ribosomal Protein S6 Kinases - metabolism | Somatostatin - adverse effects | Heart - physiology | Humans | Body Weight - drug effects | Polycystic Kidney, Autosomal Recessive - physiopathology | Ki-67 Antigen - metabolism | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Insulin - blood | Phosphoproteins - metabolism | Glucagon - blood | Somatostatin - pharmacology | Polycystic Kidney, Autosomal Recessive - pathology | Kidney - metabolism | Drug Interactions | Hyperglycemia - chemically induced | Liver - drug effects | Polycystic Kidney, Autosomal Recessive - drug therapy | Hydrocortisone - blood | Cyclic AMP - metabolism | Kidney - physiopathology | Disease Models, Animal | Somatostatin - analogs & derivatives | Kidney - drug effects | Liver - metabolism | Octreotide - adverse effects | Rats | Octreotide - therapeutic use | Octreotide - pharmacology | Animals | Receptor, IGF Type 1 - blood | Heart - drug effects | Somatostatin - therapeutic use | Blood Glucose - metabolism | Polycystic Kidney, Autosomal Recessive - metabolism | Insulin-Like Growth Factor I - metabolism | Care and treatment | Patient outcomes | Body weight | Analysis | Cyclic adenylic acid | G proteins | Health aspects | Polycystic kidney disease | Disorders | Colleges & universities | Hormones | Incidence | Anticancer properties | Proteins | Hyperglycemia | Medical science | Cell growth | Education | Inhibition | Liver diseases | Splicing | Ducts | Cyclic AMP | Metabolism | Gene expression | Insulin | Bile duct | Nephropathy | Cysts | Fibrosis | Mutation | Endocrinology | Clear cell-type renal cell carcinoma | Kidney transplantation | Cell proliferation | Animal models | Medical services | Homeostasis | Clinical trials | Stimulation | Insulin-like growth factors | Kinases | Urology | Analogs | Rodents | Primates | Safety | Age | Congenital diseases | Argipressin | Nutrition | Secretion | Health | Risk reduction | Pharmacology | Rivers | Chemical compounds | Vasopressin | Medicine | Antitumor activity | Kidney diseases | Tumors
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0131677
Journal Article
Gastroenterology, ISSN 0016-5085, 2007, Volume 132, Issue 3, pp. 1104 - 1116
Background & Aims: In polycystic liver diseases (PCLDs), increased cholangiocyte proliferation and fluid secretion are key features and cholangiocyte adenosine... 
Gastroenterology and Hepatology | KIDNEY-DISEASE | MOLECULAR CHARACTERIZATION | CYST FORMATION | CYCLIC ADENOSINE | TYROSINE KINASE INHIBITION | SOMATOSTATIN RECEPTORS | CELL-PROLIFERATION | HAN-SPRD RATS | ORTHOLOGOUS MODEL | GASTROENTEROLOGY & HEPATOLOGY | BILIARY EPITHELIUM | Cysts - etiology | Bile Ducts - metabolism | Bile Duct Diseases - etiology | Liver Diseases - pathology | Dose-Response Relationship, Drug | Polycystic Kidney, Autosomal Recessive - pathology | Cysts - metabolism | Liver - drug effects | Time Factors | Bile Duct Diseases - metabolism | Polycystic Kidney, Autosomal Recessive - complications | Liver Diseases - etiology | Liver Cirrhosis - metabolism | Polycystic Kidney, Autosomal Recessive - drug therapy | Receptors, Somatostatin - metabolism | Cyclic AMP - metabolism | Organ Culture Techniques | Disease Models, Animal | Liver Cirrhosis - etiology | Cysts - prevention & control | Kidney - drug effects | Liver Cirrhosis - prevention & control | Bile Ducts - drug effects | Liver - metabolism | Liver Diseases - prevention & control | Rats | Octreotide - therapeutic use | Cysts - pathology | Octreotide - pharmacology | Rats, Sprague-Dawley | Disease Progression | Gastrointestinal Agents - pharmacology | Animals | Bile Duct Diseases - prevention & control | Gastrointestinal Agents - therapeutic use | Receptors, Somatostatin - drug effects | Cell Proliferation - drug effects | Liver Diseases - metabolism | Polycystic Kidney, Autosomal Recessive - metabolism | Bile Duct Diseases - pathology | Adenosine | Analysis
Journal Article
Journal Article