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Protein Science, ISSN 0961-8368, 01/2013, Volume 22, Issue 1, pp. 22 - 34
A variety of antiprion compounds have been reported that are effective in ex vivo and in vivo treatment experiments. However, the molecular mechanisms for most... 
Action mechanism | Anti-prion compounds | Medical chaperones | Prion protein | BIOCHEMISTRY & MOLECULAR BIOLOGY | INFECTIVITY | CONFORMATIONS | SCRAPIE | REPLICATION | INHIBITION | PRPSC | action mechanism | DISEASE | TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY | ACCUMULATION | medical chaperones | anti-prion compounds | DERIVATIVES | prion protein | Surface Plasmon Resonance | Carbazoles - chemistry | Molecular Chaperones - metabolism | Nitriles - pharmacology | Protein Conformation - drug effects | Molecular Chaperones - chemistry | Aminopyridines - chemistry | Pentosan Sulfuric Polyester - chemistry | Pentosan Sulfuric Polyester - pharmacology | Quinacrine - pharmacology | Piperidines - pharmacology | Quinacrine - chemistry | Molecular Structure | Catechin - pharmacology | Binding Sites - drug effects | Molecular Chaperones - pharmacology | Amides - pharmacology | Prions - metabolism | Piperidines - chemistry | Magnetic Resonance Spectroscopy | Congo Red - pharmacology | Prions - chemistry | Prions - antagonists & inhibitors | Animals | Aminopyridines - pharmacology | Nitriles - chemistry | Amides - chemistry | Catechin - analogs & derivatives | Mice | Carbazoles - pharmacology | Congo Red - chemistry | Catechin - chemistry | Nuclear magnetic resonance spectroscopy | Universities and colleges | Chemical properties | Precipitation (Meteorology) | Prions | Protein binding | Proteins | Binding sites
Journal Article
Biomaterials, ISSN 0142-9612, 09/2018, Volume 178, pp. 351 - 362
Journal Article
Journal Article
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 05/2010, Volume 99, Issue 5, pp. 2386 - 2398
The silicon phthalocyanine Pc 4 is a second‐generation photosensitizer that has several properties superior to other photosensitizers currently approved by the... 
micelle | nanoparticles | biocompatibility | controlled delivery | formulation | cancer | polymeric drug delivery systems | Nanoparticles | Controlled delivery | Polymeric drug delivery systems | Formulation | Micelle | Biocompatibility | Cancer | CHEMISTRY, MEDICINAL | TARGETED PHOTODYNAMIC THERAPY | DRUG-DELIVERY | POLYMERIC MICELLES | ZINC(II) PHTHALOCYANINE | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLE PLATFORMS | POLYION COMPLEX MICELLES | PHTHALOCYANINE PHOTOSENSITIZERS | PHARMACOLOGY & PHARMACY | COPOLYMER | LIPOSOMES | Organosilicon Compounds - pharmacology | Apoptosis - drug effects | Apoptosis - radiation effects | Photochemotherapy - methods | Biocompatible Materials - chemistry | Humans | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Indoles - administration & dosage | Photosensitizing Agents - administration & dosage | Organosilicon Compounds - administration & dosage | Photosensitizing Agents - pharmacology | Micelles | Drug Compounding | Indoles - pharmacology | Polyethylene Glycols - pharmacology | Cell Survival - drug effects | Solubility | Biocompatible Materials - pharmacology | Cell Survival - radiation effects | Drug Carriers - pharmacology | Particle Size | Polyesters - pharmacology | Polyesters - chemistry | Cell Line, Tumor | Photosensitizing Agents - pharmacokinetics | Indoles - pharmacokinetics | Organosilicon Compounds - pharmacokinetics
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 01/2016, Volume 30, pp. 144 - 154
imaging and biodistribution analysis of nude mice bearing HepG2 tumors after tail vein injection of free IR-780, or IR-780 loaded TPGS-PLA/NPs or... 
Liver targeting | Dopamine polymerization | Surface modification | Cancer nanotechnology | Galactosylated nanoparticles | Taxoids - pharmacology | Nanoparticles - chemistry | Humans | Vitamin E - analogs & derivatives | Polyethylene Glycols - chemistry | Lactic Acid - pharmacokinetics | Liver Neoplasms, Experimental - metabolism | Carcinoma, Hepatocellular - drug therapy | Polyesters | Indoles - pharmacology | Vitamin E - chemistry | Lactic Acid - pharmacology | Liver Neoplasms, Experimental - pathology | Polyethylene Glycols - pharmacology | Taxoids - chemistry | Lactic Acid - chemistry | Vitamin E - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Hep G2 Cells | Taxoids - pharmacokinetics | Xenograft Model Antitumor Assays | Animals | Liver Neoplasms, Experimental - drug therapy | Mice, Nude | Carcinoma, Hepatocellular - pathology | Polymers - pharmacokinetics | Polymers - pharmacology | Indoles - pharmacokinetics | Polymers - chemistry | Mice | Drug Delivery Systems - methods | Indoles - chemistry | Carcinoma, Hepatocellular - metabolism | Vitamin E - pharmacology | Drugs | Liver cancer | Drug delivery systems | Docetaxel | Vehicles | Nanoparticles | Polyethylene glycol | Tocopherols | Polymerization | Polyols | Nanotechnology | Surgical implants | Biomedical materials | In vivo testing | Liver | In vivo tests | Palladium | Tumors | Cancer
Journal Article
Journal Article
Journal Article
Theranostics, ISSN 1838-7640, 2018, Volume 8, Issue 6, pp. 1558 - 1574
The combination of chemotherapy with photodynamic therapy (PDT) has attracted broad attention as it can overcome limitations of conventional chemo-treatment by... 
Hypoxia relieve | Oxygen generation | Manganese dioxide nanoparticles | Combination therapy | Theranostics | Multifunctional nanoparticles | MEDICINE, RESEARCH & EXPERIMENTAL | DRUG-DELIVERY | manganese dioxide nanoparticles | HYPOXIA | SEMICONDUCTING POLYMER | CANCER-THERAPY | PHOTOTHERMAL THERAPY | oxygen generation | ALBUMIN-MNO2 NANOPARTICLES | RESISTANCE | combination therapy | theranostics | SOLID TUMOR MICROENVIRONMENT | MICE | hypoxia relieve | MNO2 NANOPARTICLES | Oxygen - pharmacology | Photosensitizing Agents - chemistry | Nanoparticles - chemistry | Humans | Oxides - chemistry | Porphyrins - chemistry | Magnetic Resonance Imaging - methods | Polyethylene Glycols - chemistry | Doxorubicin - chemistry | Photoacoustic Techniques | Photochemotherapy | Oxygen - metabolism | Breast Neoplasms - metabolism | Drug Carriers | Breast Neoplasms - therapy | Photosensitizing Agents - pharmacology | Theranostic Nanomedicine - methods | MCF-7 Cells | Nanoparticles - therapeutic use | Oxygen - chemistry | Female | Antineoplastic Agents - pharmacology | Manganese Compounds - chemistry | Drug Compounding - methods | Porphyrins - pharmacology | Antineoplastic Agents - chemistry | Xenograft Model Antitumor Assays | Oxides - pharmacology | Polyesters - chemistry | Animals | Breast Neoplasms - pathology | Mice, Nude | Cell Line, Tumor | Combined Modality Therapy - methods | Mice | Manganese Compounds - pharmacology | Doxorubicin - pharmacology
Journal Article