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Journal of Controlled Release, ISSN 0168-3659, 12/2015, Volume 220, Issue Pt A, pp. 529 - 544
Hypoxia is a characteristic of cancer and plays a key role in tumorigenesis, angiogenesis and resistance to cancer therapies. SiRNA treatment is effective... 
siRNA delivery | Hypoxia | Quantum dots | pH-responsive | SYSTEMIC DELIVERY | DESIGN | BIODISTRIBUTION | CHEMISTRY, MULTIDISCIPLINARY | CO-DELIVERY | IN-VITRO | METABOLISM | CISPLATIN | RESISTANCE | PHARMACOLOGY & PHARMACY | HUMAN HEAD | EXPRESSION | RNA, Small Interfering - genetics | Deoxyglucose - metabolism | Humans | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Glucose Transporter Type 1 - metabolism | RNAi Therapeutics - adverse effects | Liver Neoplasms - therapy | Gene Transfer Techniques - adverse effects | Oxygen - metabolism | Thioctic Acid - metabolism | Cell Hypoxia | RNA, Small Interfering - chemistry | Peptides - metabolism | MCF-7 Cells | Time Factors | Cadmium Compounds - toxicity | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Liver Neoplasms - pathology | Lysine - metabolism | Tellurium - toxicity | Polyethylene Glycols - metabolism | Cadmium Compounds - chemistry | Liver Neoplasms - genetics | Cell Survival | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Tellurium - chemistry | Tellurium - metabolism | Tumor Burden | Hydrazones - metabolism | RNAi Therapeutics - methods | Hep G2 Cells | Xenograft Model Antitumor Assays | Animals | Quantum Dots | Mice, Nude | Liver Neoplasms - metabolism | Mice, Inbred BALB C | Cadmium Compounds - metabolism | Hydrogen-Ion Concentration | RNA, Small Interfering - metabolism | Nuclear magnetic resonance spectroscopy | Genetic engineering | Hydrogen-ion concentration | Mass spectrometry | Polyols | Tumors | Drugstores | Liquid chromatography | Sulfates | Surface active agents | Lysine | Polyethylene glycol | Pharmacy | Cancer | Index Medicus
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 79 - 10
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2015, Volume 60, Issue 2, pp. 208 - 219
Eukaryotic cells possess numerous dynamic membrane-less organelles, RNP granules, enriched in RNA and RNA-binding proteins containing disordered regions. We... 
TRANSITION | EUKARYOTIC STRESS GRANULES | CELL-FREE FORMATION | PRION-LIKE DOMAINS | NUCLEOLI | BEHAVIOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGIONS | BODIES | P GRANULES | AGGREGATION | CELL BIOLOGY | Organelles - chemistry | Fluorescence Recovery After Photobleaching | Humans | Polyethylene Glycols - chemistry | Amyloid - chemistry | Cytoplasmic Granules - chemistry | Molecular Mimicry | Amyloid - metabolism | Protein Aggregation, Pathological - pathology | Solutions | Cytoplasmic Granules - metabolism | Escherichia coli - metabolism | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - genetics | Protein Aggregation, Pathological - genetics | RNA - metabolism | Sodium Chloride - chemistry | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amyloid - genetics | Gene Expression | Recombinant Proteins - chemistry | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - metabolism | Recombinant Proteins - genetics | RNA - chemistry | Intrinsically Disordered Proteins - genetics | Heterogeneous Nuclear Ribonucleoprotein A1 | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - chemistry | Escherichia coli - genetics | Intrinsically Disordered Proteins - chemistry | Protein Binding | Organelles - metabolism | Protein Aggregation, Pathological - metabolism | Intrinsically Disordered Proteins - metabolism | Fluorescence | Marine biology | Chemical properties | RNA | Binding proteins | Protein binding | Yuan (China)
Journal Article
Diabetes, ISSN 0012-1797, 12/2016, Volume 65, Issue 12, pp. 3765 - 3775
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 09/2016, Volume 238, pp. 139 - 148
Therapeutic nanoparticles (NPs) approved for clinical use in solid tumor therapy provide only modest improvements in patient survival, in part due to... 
Nanoparticles | Intravital microscopy | Multiple particle tracking (MPT) | PEG density | Surface plasmon resonance (SPR) | Tumor tissue penetration | SOLID TUMORS | DEEP PENETRATION | CHEMISTRY, MULTIDISCIPLINARY | PHASE-III TRIAL | BREAST-CANCER | DELIVERY-SYSTEM | IN-VIVO | PHARMACOLOGY & PHARMACY | EXTRACELLULAR-MATRIX | HUMAN MUCUS | Neoplasms - metabolism | Nanoparticles - analysis | Humans | Polyethylene Glycols - analysis | Drug Carriers - analysis | Albumin-Bound Paclitaxel - administration & dosage | Antineoplastic Agents - administration & dosage | Polyglycolic Acid - analysis | Breast - metabolism | Breast Neoplasms - metabolism | Antineoplastic Agents - metabolism | Nanoparticles - metabolism | Surface Properties | Doxorubicin - analogs & derivatives | Female | Doxorubicin - metabolism | Polyglycolic Acid - metabolism | Diffusion | Lactic Acid - analysis | Doxorubicin - administration & dosage | Albumin-Bound Paclitaxel - metabolism | Polyethylene Glycols - metabolism | Drug Carriers - metabolism | Lactic Acid - metabolism | Proteoglycans - metabolism | Breast Neoplasms - drug therapy | Polyethylene Glycols - administration & dosage | Neoplasms - drug therapy | Particle Size | Collagen - metabolism | Animals | Breast - drug effects | Mice, Nude | Cell Line, Tumor | Mice | Laminin - metabolism | Drug Combinations | Drugs | Ethylene glycol | Drug delivery systems | Drug therapy | Drug approval | Tumors | Vehicles | Medical colleges | Cancer | multiple particle tracking (MPT) | tumor tissue penetration | surface plasmon resonance (SPR) | nanoparticles | intravital microscopy
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2008, Volume 3, Issue 4, pp. e2069 - e2069
Journal Article
Circulation Research, ISSN 0009-7330, 04/2012, Volume 110, Issue 9, pp. 1217 - 1225
RATIONALE:The function of Nox4, a source of vascular H2O2, is unknown. Other Nox proteins were identified as mediators of endothelial dysfunction. OBJECTIVE:We... 
Hypertension | Angiogenesis | Carbon monoxide | Nitric oxide | Redox regulation | INDUCED ACTIVATION | nitric oxide | CARDIAC & CARDIOVASCULAR SYSTEMS | redox regulation | angiogenesis | carbon monoxide | ANGIOTENSIN-II | BLOOD-PRESSURE | NAD(P)H OXIDASE | ENDOTHELIAL-CELLS | IN-VIVO | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HYDROGEN-PEROXIDE | HEMATOLOGY | hypertension | UP-REGULATION | Catalase - pharmacology | Heme Oxygenase-1 - metabolism | Humans | NADPH Oxidases - metabolism | Male | Ischemia - genetics | Carbonates - pharmacology | RNA, Messenger - metabolism | NADPH Oxidases - deficiency | Time Factors | NADPH Oxidases - genetics | Carbonates - metabolism | Hemin - pharmacology | Hypertension - enzymology | Hypertension - genetics | Ischemia - pathology | Cytoprotection | Disease Models, Animal | Muscle, Skeletal - blood supply | NADH, NADPH Oxidoreductases - genetics | Hypertension - pathology | Hydrogen Peroxide - metabolism | Mice, Knockout | Human Umbilical Vein Endothelial Cells - enzymology | Organometallic Compounds - metabolism | Mice | Oxidative Stress - drug effects | Endothelial Cells - pathology | Endothelial Cells - enzymology | Hypertrophy | Ischemia - enzymology | Boranes - metabolism | Transfection | NADH, NADPH Oxidoreductases - deficiency | Hypertension - chemically induced | NF-E2-Related Factor 2 - genetics | Membrane Proteins - metabolism | Nitric Oxide Synthase Type III - metabolism | Angiotensin II | Polyethylene Glycols - pharmacology | Carbon Dioxide - metabolism | Mice, Inbred C57BL | Cells, Cultured | Boranes - pharmacology | Antioxidants - pharmacology | Ischemia - physiopathology | NADPH Oxidase 4 | Hypertension - physiopathology | NADPH Oxidase 1 | Animals | Lung - blood supply | Neovascularization, Physiologic | Organometallic Compounds - pharmacology | Apoptosis | Endothelial Cells - drug effects
Journal Article
Blood, ISSN 0006-4971, 2013, Volume 122, Issue 15, pp. 2757 - 2764
Journal Article