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Journal of Controlled Release, ISSN 0168-3659, 2007, Volume 123, Issue 1, pp. 19 - 26
Polymeric micelles were constructed from poly( -lactic acid) (PLA; 3K)- -poly(ethylene glycol) (PEG; 2K)- -poly( -histidine) (polyHis; 5K) as a tumor... 
Flower-like micelle | Triggered drug release | Poly( l-histidine)- b-PEG- b-poly( l-lactic acid) triblock copolymer | Tumor pH | Poly(l-histidine)-b-PEG-b-poly(l-lactic acid) triblock copolymer | ASSOCIATIVE POLYMERS | SENSITIVE POLYMERIC MICELLES | SOLID TUMORS | poly(L-histidine)-b-PEG-b-poly(L-lactic acid) triblock copolymer | BLOCK-COPOLYMER MICELLES | CHEMISTRY, MULTIDISCIPLINARY | triggered drug release | IN-VITRO | DEPENDENT AGGREGATION | ACETATE NANOPARTICLES PAN | PHARMACOLOGY & PHARMACY | tumor pH | POORLY SOLUBLE DRUGS | EXTRACELLULAR PH | DRUG-DELIVERY SYSTEMS | flower-like micelle | Histidine - administration & dosage | Cell Survival - drug effects | Polymers - administration & dosage | Lactic Acid - chemistry | Humans | Polyethylene Glycols - chemistry | Antineoplastic Agents - administration & dosage | Antineoplastic Agents - chemistry | Polyethylene Glycols - administration & dosage | Neoplasms - drug therapy | Hydrogen-Ion Concentration - drug effects | Micelles | Cell Line, Tumor | Polyesters | Polymers - chemistry | Histidine - chemistry | Neoplasms - pathology | Lactic Acid - administration & dosage | Cell Survival - physiology | Drugs | Ethylene glycol | Drug delivery systems | Block copolymers | Organic acids | Vehicles | Tumors | Index Medicus | Poly(L-histidine)-b-PEG-b-poly(L-lactic acid) triblock copolymer
Journal Article
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 2014, Volume 32, Issue 13, pp. 1302 - 1308
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 03/2017, Volume 12, pp. 2117 - 2127
The blood-brain barrier is a formidable obstacle for glioma chemotherapy due to its compact structure and drug efflux ability. In this study, a dual-targeting... 
Biodegradable polymersomes | Angiopep-2 | Glioma treatment | Dual targeting | Doxorubicin | SOLID TUMORS | PENETRATION | NANOSCIENCE & NANOTECHNOLOGY | dual targeting | glioma treatment | BLOOD-BRAIN-BARRIER | CHEMOTHERAPY | ADJUVANT TEMOZOLOMIDE | GLIOBLASTOMA | PHARMACOLOGY & PHARMACY | biodegradable polymersomes | doxorubicin | RADIOTHERAPY | BLOCK-COPOLYMER | DENSITY-LIPOPROTEIN RECEPTOR | Rats, Wistar | Drug Carriers - administration & dosage | Male | Polyethylene Glycols - chemistry | Doxorubicin - chemistry | Drug Carriers - chemistry | Peptides - administration & dosage | Antibiotics, Antineoplastic - chemistry | Polyesters - administration & dosage | Antibiotics, Antineoplastic - pharmacokinetics | Doxorubicin - administration & dosage | Peptides - chemistry | Receptors, LDL - metabolism | Permeability | Blood-Brain Barrier - drug effects | Polyethylene Glycols - administration & dosage | Blood-Brain Barrier - metabolism | Antibiotics, Antineoplastic - administration & dosage | Polyesters - chemistry | Animals | Drug Carriers - pharmacokinetics | Cryoelectron Microscopy - methods | Drug Delivery Systems - methods | Glioma - drug therapy | Hydrogen-Ion Concentration | Drugs | Ethylene glycol | Usage | Drug delivery systems | Gliomas | Physiological aspects | Research | Drug therapy | Vehicles | Index Medicus
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 04/2014, Volume 464, Issue 1-2, pp. 178 - 184
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2010, Volume 16, Issue 24, pp. 6139 - 6149
Purpose: A novel nanomedicine, CYT-6091, constructed by simultaneously binding recombinant human tumor necrosis factor alpha (rhTNF) and thiolyated... 
TRIAL | TUMOR-NECROSIS-FACTOR | INTERFERON-GAMMA | ONCOLOGY | RTNF-ALPHA | ADVANCED MALIGNANT DISEASE | TNF-ALPHA | ISOLATED LIMB PERFUSION | MELPHALAN | SOFT-TISSUE SARCOMA | FACTOR-ALPHA | Neoplasms - metabolism | Injections, Intravenous | Nanoparticles - chemistry | Gold Colloid - administration & dosage | Humans | Middle Aged | Polyethylene Glycols - adverse effects | Male | Polyethylene Glycols - chemistry | Recombinant Proteins - pharmacokinetics | Antineoplastic Agents - administration & dosage | Recombinant Proteins - adverse effects | Dose-Response Relationship, Drug | Young Adult | Gold Colloid - pharmacokinetics | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Recombinant Proteins - chemistry | Gold Colloid - adverse effects | Gold Colloid - chemistry | Antineoplastic Agents - chemistry | Polyethylene Glycols - administration & dosage | Recombinant Proteins - administration & dosage | Neoplasms - drug therapy | Maximum Tolerated Dose | Tumor Necrosis Factor-alpha - adverse effects | Tumor Necrosis Factor-alpha - chemistry | Adolescent | Tumor Necrosis Factor-alpha - administration & dosage | Aged | Nanoparticles - administration & dosage | Tumor Necrosis Factor-alpha - pharmacokinetics | Neoplasms - pathology | Index Medicus
Journal Article