X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (10998) 10998
Newspaper Article (368) 368
Newsletter (79) 79
Book Chapter (20) 20
Magazine Article (18) 18
Trade Publication Article (4) 4
Book / eBook (3) 3
Dissertation (3) 3
Government Document (3) 3
Conference Proceeding (2) 2
Reference (2) 2
Web Resource (2) 2
Report (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (5899) 5899
humans (5621) 5621
polyethylene glycols - chemistry (4615) 4615
pharmacology & pharmacy (4059) 4059
male (3311) 3311
polyethylene glycol (3236) 3236
mice (2892) 2892
nanoparticles (2762) 2762
female (2755) 2755
drug delivery systems (2498) 2498
pharmacokinetics (1999) 1999
rats (1890) 1890
polyethylene glycols - pharmacokinetics (1793) 1793
cancer (1754) 1754
chemistry, multidisciplinary (1647) 1647
drugs (1596) 1596
cell line, tumor (1578) 1578
drug-delivery (1503) 1503
polyethylene glycols - administration & dosage (1479) 1479
particle size (1431) 1431
drug carriers - chemistry (1308) 1308
tissue distribution (1274) 1274
liposomes (1203) 1203
nanoscience & nanotechnology (1175) 1175
analysis (1167) 1167
nanoparticles - chemistry (1140) 1140
vehicles (1086) 1086
in-vitro (1084) 1084
micelles (1058) 1058
delivery (1048) 1048
polyethylene glycols (1027) 1027
tumors (992) 992
adult (961) 961
polyethylene glycols - therapeutic use (955) 955
chemotherapy (949) 949
solubility (938) 938
rats, sprague-dawley (936) 936
middle aged (913) 913
poly (908) 908
mice, inbred balb c (906) 906
doxorubicin (889) 889
proteins (878) 878
in-vivo (871) 871
materials science, biomaterials (867) 867
polyethylene glycols - pharmacology (863) 863
polyethylene-glycol (861) 861
polymers (842) 842
oncology (839) 839
therapy (820) 820
drug delivery (811) 811
research (809) 809
biochemistry & molecular biology (783) 783
treatment outcome (777) 777
medicine (724) 724
permeability (713) 713
drug delivery systems - methods (706) 706
drug carriers (705) 705
biodistribution (697) 697
antineoplastic agents - administration & dosage (682) 682
polyols (679) 679
toxicity (679) 679
pharmacy (677) 677
bioavailability (674) 674
mice, nude (674) 674
pegylation (669) 669
health aspects (668) 668
cell survival - drug effects (654) 654
cells (641) 641
engineering, biomedical (633) 633
antineoplastic agents - pharmacokinetics (632) 632
biological availability (632) 632
care and treatment (616) 616
doxorubicin - administration & dosage (616) 616
recombinant proteins (612) 612
cytotoxicity (604) 604
polymers - chemistry (597) 597
nanotechnology (596) 596
half-life (570) 570
aged (568) 568
dose-response relationship, drug (567) 567
pharmacology/toxicology (566) 566
polyethylene (566) 566
release (555) 555
antineoplastic agents - chemistry (544) 544
chemistry, medicinal (543) 543
interferon-alpha - therapeutic use (542) 542
drug stability (541) 541
polyethylene glycols - adverse effects (541) 541
hydrogen-ion concentration (540) 540
ethylene glycol (539) 539
original research (532) 532
paclitaxel (529) 529
pharmacology (529) 529
cancer therapies (528) 528
peptides (527) 527
molecular weight (520) 520
liposomes - chemistry (514) 514
antiviral agents - therapeutic use (499) 499
hepatitis c, chronic - drug therapy (499) 499
medicine, research & experimental (499) 499
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (11414) 11414
Japanese (96) 96
Chinese (77) 77
Russian (21) 21
German (13) 13
French (12) 12
Polish (5) 5
Spanish (5) 5
Hungarian (3) 3
Portuguese (3) 3
Slovak (2) 2
Arabic (1) 1
Korean (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Scientific reports, ISSN 2045-2322, 2015, Volume 5, Issue 1, p. 11337
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 1, p. e82331
Brain cancer is a devastating disease affecting many people worldwide. Effective treatment with chemotherapeutics is limited due to the presence of the... 
MALIGNANT GLIOMA | CELLS | TRANSPORT | MULTIDISCIPLINARY SCIENCES | BARRIER | METASTASES | ADRIAMYCIN | BIODISTRIBUTION | MODEL | CHEMOTHERAPY | PACLITAXEL | Doxorubicin - blood | Glutathione - pharmacokinetics | Doxorubicin - therapeutic use | Capillaries - pathology | Humans | Brain Neoplasms - pathology | Body Weight - drug effects | Polyethylene Glycols - therapeutic use | Drug Delivery Systems | Brain - blood supply | Glutathione - pharmacology | Time Factors | Doxorubicin - analogs & derivatives | Female | Polyethylene Glycols - pharmacology | Glutathione - therapeutic use | Tissue Distribution - drug effects | Glutathione - analogs & derivatives | Endothelial Cells - metabolism | Polyethylene Glycols - pharmacokinetics | Treatment Outcome | Brain Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Brain - drug effects | Animals | Mice, Nude | Glioblastoma - pathology | Survival Analysis | Brain - pathology | Cell Proliferation - drug effects | Mice | Brain Neoplasms - ultrastructure | Endothelial Cells - pathology | Glioblastoma - drug therapy | Doxorubicin - pharmacology | Glutathione - blood | Drugs | Plasma physics | Drug delivery systems | Anthracyclines | Thiols | Gliomas | Brain tumors | Drug therapy | Cancer | Vehicles | Nuclear medicine | Bioluminescence | Neurosciences | Brain cancer | Glioblastoma | Drug delivery | Metastasis | Cancer therapies | Doxorubicin | Antioxidants | Blood-brain barrier | Inhibition | Xenobiotics | Glutathione | Medical treatment | Pharmacology | Breast cancer | Disease control | Endothelial cells | Studies | Chemotherapy | Brain research | Diffusion barriers | Medical prognosis | Pharmacokinetics | Tumors
Journal Article
Acta biomaterialia, ISSN 1742-7061, 2016, Volume 30, pp. 144 - 154
...-tocopherol polyethylene glycol 1000 succinate-poly(lactide) (pD-TPGS-PLA/NPs). To target liver cancer cells, galactosamine was conjugated on the prepared... 
Liver targeting | Dopamine polymerization | Surface modification | Cancer nanotechnology | Galactosylated nanoparticles | Taxoids - pharmacology | Nanoparticles - chemistry | Humans | Vitamin E - analogs & derivatives | Polyethylene Glycols - chemistry | Lactic Acid - pharmacokinetics | Liver Neoplasms, Experimental - metabolism | Carcinoma, Hepatocellular - drug therapy | Polyesters | Indoles - pharmacology | Vitamin E - chemistry | Lactic Acid - pharmacology | Liver Neoplasms, Experimental - pathology | Polyethylene Glycols - pharmacology | Taxoids - chemistry | Lactic Acid - chemistry | Vitamin E - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Hep G2 Cells | Taxoids - pharmacokinetics | Xenograft Model Antitumor Assays | Animals | Liver Neoplasms, Experimental - drug therapy | Mice, Nude | Carcinoma, Hepatocellular - pathology | Polymers - pharmacokinetics | Polymers - pharmacology | Indoles - pharmacokinetics | Polymers - chemistry | Mice | Drug Delivery Systems - methods | Indoles - chemistry | Carcinoma, Hepatocellular - metabolism | Vitamin E - pharmacology | Drugs | Liver cancer | Drug delivery systems | Docetaxel | Vehicles | Nanoparticles | Polyethylene glycol | Tocopherols | Polymerization | Polyols | Nanotechnology | Surgical implants | Biomedical materials | In vivo testing | Liver | In vivo tests | Palladium | Tumors | Cancer
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 20, pp. 5414 - 5424
... (ECM-targeting liposomes), crosslinked from methoxy-poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide-co-histidine... 
Advanced Basic Science | Dentistry | Tumor ECM-induced targeting | Intracellular drug delivery | Liposomes | Polymers | Cancer therapy | MATERIALS SCIENCE, BIOMATERIALS | STERICALLY STABILIZED LIPOSOMES | ENGINEERING, BIOMEDICAL | DOXORUBICIN | ECM-induced targeting | PHARMACOKINETICS | POLY(ETHYLENE GLYCOL) | SENSITIVE LIPOSOMES | DESTABILIZATION | IN-VIVO | Tumor | SYSTEMS | BEARING | COMPLEXATION | Humans | Extracellular Matrix - metabolism | Polyethylene Glycols - chemistry | Doxorubicin - chemistry | Acrylamides - pharmacokinetics | Biotin - chemistry | Tissue Distribution | Female | Antineoplastic Agents - pharmacokinetics | Disease Models, Animal | Biotin - pharmacokinetics | Extracellular Matrix - drug effects | HCT116 Cells | Polyethylene Glycols - pharmacokinetics | Antineoplastic Agents - chemistry | Doxorubicin - pharmacokinetics | Acrylamides - chemistry | Neoplasms - drug therapy | Liposomes - chemistry | Animals | Mice, Nude | Polymers - pharmacokinetics | Polymers - chemistry | Mice | Mice, Inbred BALB C | Drug Delivery Systems - methods | Liposomes - pharmacokinetics | Biotin - analogs & derivatives | Hydrogen-Ion Concentration | Drugs | Ethylene glycol | Drug delivery systems | Hydrogen | Antineoplastic agents | Vehicles | Antimitotic agents | Crosslinked polymers | Histidine | Polymer industry | Drug therapy | Hydrogen-ion concentration | Health aspects | Cancer | Biomedical engineering | Polyols | Polyethylene glycol | Index Medicus
Journal Article
Journal Article
Clinical cancer research, ISSN 1557-3265, 2010, Volume 16, Issue 24, pp. 6139 - 6149
...) and thiolyated polyethylene glycol to the surface of 27-nm colloidal gold particles, was tested in a phase I dose escalation clinical trial in advanced stage cancer patients... 
TRIAL | TUMOR-NECROSIS-FACTOR | INTERFERON-GAMMA | ONCOLOGY | RTNF-ALPHA | ADVANCED MALIGNANT DISEASE | TNF-ALPHA | ISOLATED LIMB PERFUSION | MELPHALAN | SOFT-TISSUE SARCOMA | FACTOR-ALPHA | Neoplasms - metabolism | Injections, Intravenous | Nanoparticles - chemistry | Gold Colloid - administration & dosage | Humans | Middle Aged | Polyethylene Glycols - adverse effects | Male | Polyethylene Glycols - chemistry | Recombinant Proteins - pharmacokinetics | Antineoplastic Agents - administration & dosage | Recombinant Proteins - adverse effects | Dose-Response Relationship, Drug | Young Adult | Gold Colloid - pharmacokinetics | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Recombinant Proteins - chemistry | Gold Colloid - adverse effects | Gold Colloid - chemistry | Antineoplastic Agents - chemistry | Polyethylene Glycols - administration & dosage | Recombinant Proteins - administration & dosage | Neoplasms - drug therapy | Maximum Tolerated Dose | Tumor Necrosis Factor-alpha - adverse effects | Tumor Necrosis Factor-alpha - chemistry | Adolescent | Tumor Necrosis Factor-alpha - administration & dosage | Aged | Nanoparticles - administration & dosage | Tumor Necrosis Factor-alpha - pharmacokinetics | Neoplasms - pathology
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0179431
.... NKTR-214 is a clinical-stage biologic that comprises interleukin-2 (IL2) protein bound by multiple releasable polyethylene glycol (PEG) chains... 
LIGAND-BINDING | ALPHA-RECEPTOR | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | COMPLEXES | REGULATORY T-CELLS | MODULATION THERAPIES | IL-2 | CYTOKINE | HIGH-DOSE INTERLEUKIN-2 | RENAL-CELL CARCINOMA | Neoplasms - metabolism | T-Lymphocytes, Regulatory - metabolism | Immunotherapy - methods | Interleukin-2 Receptor beta Subunit - metabolism | Interleukin Receptor Common gamma Subunit - metabolism | Transplantation, Homologous | T-Lymphocytes, Regulatory - immunology | STAT5 Transcription Factor - metabolism | Neoplasms - therapy | Interleukin Receptor Common gamma Subunit - agonists | CD8-Positive T-Lymphocytes - metabolism | Female | Interleukin-2 - analogs & derivatives | Phosphorylation - drug effects | Polyethylene Glycols - pharmacology | Models, Theoretical | Tumor Microenvironment - drug effects | Interleukin-2 - pharmacokinetics | Interleukin-2 Receptor beta Subunit - agonists | Mice, Inbred C57BL | Polyethylene Glycols - pharmacokinetics | Receptors, Interleukin-2 - metabolism | Mice, Inbred C3H | Tumor Microenvironment - immunology | T-Lymphocytes, Regulatory - drug effects | Algorithms | Animals | Interleukin-2 Receptor alpha Subunit - agonists | Interleukin-2 Receptor alpha Subunit - metabolism | Prodrugs - pharmacokinetics | Neoplasms - immunology | CD8-Positive T-Lymphocytes - drug effects | Cell Line, Tumor | Drug Liberation | Interleukin-2 - pharmacology | Mice, Inbred BALB C | Kinetics | CD8-Positive T-Lymphocytes - immunology | Prodrugs - pharmacology | Receptors, Interleukin-2 - agonists | Physiological aspects | Care and treatment | Interleukin-2 | Immunotherapy | Patient outcomes | Cancer | Polyethylenes | Conjugates | CD8 antigen | Interleukin | Lymphocytes T | Anticancer properties | Proteins | Biological effects | Cell activation | Immunology | Interleukin 2 | Lymphocytes | Polyethylene glycol | Modelling | Drug dosages | Immune system | Interleukin 2 receptors | Pharmacodynamics | Cytokines | Immunoregulation | Melanoma | Pharmacology | Affinity | Ligands | Mutation | Pharmacokinetics | In vitro methods and tests | Tumors
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 02/2015, Volume 55, Issue 2, pp. 152 - 158
Journal Article
Journal Article