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Pharmacological Research, ISSN 1043-6618, 12/2014, Volume 90, pp. 25 - 35
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2004, Volume 109, Issue 1, pp. 1 - 8
Heme oxygenase‐1 (HO‐1), an inducible enzyme that catalyzes oxidative degradation of heme to form biliverdin, carbon monoxide and free iron, may protect tumor... 
heme oxygenase‐1 | zinc protoporphyrin | macromolecular therapeutics | tumor targeting/EPR effect | D‐amino acid oxidase | Macromolecular therapeutics | D-amino acid oxidase | Tumor targeting/EPR effect | Heme oxygenase-1 | Zinc protoporphyrin | HUMAN BRAIN-TUMORS | CANCER-CHEMOTHERAPY | INDUCED APOPTOSIS | NITRIC-OXIDE SYNTHASE | heme oxygenase-1 | MACROMOLECULAR DRUGS | MESSENGER-RNA | ONCOLOGY | GENE-EXPRESSION | SOLID TUMOR | HYDROGEN-PEROXIDE PRODUCTION | TARGETED DELIVERY | Oxidants - pharmacology | Body Weight | Reactive Oxygen Species - metabolism | Oxidative Stress | Coloring Agents - pharmacology | Annexin A5 - pharmacology | Humans | Male | Metalloporphyrins - pharmacology | Oxygen - metabolism | Dose-Response Relationship, Drug | Antineoplastic Agents - pharmacology | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Polyethylene Glycols - pharmacology | Oxidation-Reduction | Hydrogen Peroxide - pharmacology | Etoposide - pharmacology | Tetrazolium Salts - pharmacology | Cisplatin - pharmacology | Hydrogen Peroxide - metabolism | Mitomycin - pharmacology | Neoplasms - drug therapy | Proline - chemistry | Drug Synergism | Animals | Cell Line, Tumor | Mice | Thiazoles - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Camptothecin - pharmacology | Doxorubicin - pharmacology | Apoptosis
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2014, Volume 171, Issue 11, pp. 2751 - 2766
Background and Purpose Cardiovascular risk is higher in men and postmenopausal women compared with premenopausal women. This may be due to sex differences in... 
porcine coronary artery (PCA) | gap junctions | endothelium‐derived hyperpolarization (EDH) | nitric oxide (NO) | intermediate‐conductance calcium‐activated K+ channel (IKca) | connexin (Cx) | bradykinin | hydrogen peroxide (H2O2) | small‐conductance calcium‐activated K+ channel (SKca) | sex differences | endothelium-derived hyperpolarization (EDH) | small-conductance calcium-activated K+ channel (SKc(a)) | MESENTERIC-ARTERIES | CA2+-ACTIVATED K+ CHANNELS | ACTIVATED POTASSIUM CHANNELS | intermediate-conductance calcium-activated K+ channel (IKca) | HYPERPOLARIZING FACTOR | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | PIG CAROTID-ARTERY | HYDROGEN-PEROXIDE | DEPENDENT RELAXATIONS | GENDER-DIFFERENCES | SMALL-CONDUCTANCE | Catalase - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Coronary Vessels - physiology | Glycyrrhetinic Acid - analogs & derivatives | Hydrogen Peroxide - pharmacology | Male | Sex Characteristics | Apamin - pharmacology | Indomethacin - pharmacology | Vasodilation | Connexins - metabolism | Endothelium, Vascular - physiology | Carbenoxolone - pharmacology | Glycyrrhetinic Acid - pharmacology | Animals | Gap Junctions - physiology | Swine | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Female | Bradykinin - pharmacology | Polyethylene Glycols - pharmacology | Pyrazoles - pharmacology | Postmenopausal women | Hydrogen peroxide | Nitric oxide | Arteries | Endothelium | Research Papers | small-conductance calcium-activated K+ channel (SKca)
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2011, Volume 37, Issue 3, pp. 353 - 357
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 21, pp. 5591 - 5604
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2012, Volume 56, Issue 11, pp. 5728 - 5734
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 03/2013, Volume 57, Issue 3, pp. 1312 - 1322
Journal Article
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9760, pp. 165 - 177
Summary The approval of febuxostat, a non-purine-analogue inhibitor of xanthine oxidase, by the European Medicines Agency and the US Food and Drug... 
Internal Medicine | URATE OXIDASE | MEDICINE, GENERAL & INTERNAL | SERUM URATE | XANTHINE-OXIDASE | PEGLOTICASE PGL THERAPY | DOUBLE-BLIND | PURINE SELECTIVE INHIBITOR | EVIDENCE BASED RECOMMENDATIONS | FEBUXOSTAT TMX-67 | ASPERGILLUS-FLAVUS | TREATMENT-FAILURE GOUT | Recombinant Fusion Proteins - pharmacology | Urate Oxidase - pharmacology | United States | Humans | Gout - drug therapy | Thiazoles - administration & dosage | Drug Approval | Thiazoles - adverse effects | Interleukin 1 Receptor Antagonist Protein - pharmacology | Interleukin-1 - antagonists & inhibitors | United States Food and Drug Administration | Xanthine Oxidase - antagonists & inhibitors | Polyethylene Glycols - pharmacology | Uric Acid - metabolism | Drug Administration Schedule | Febuxostat | Antibodies, Monoclonal - pharmacology | Europe | Enzyme Inhibitors - pharmacology | Clinical Trials as Topic | Gout Suppressants - adverse effects | Randomized Controlled Trials as Topic | Gout Suppressants - administration & dosage | Gout - metabolism | Uricosuric Agents - pharmacology | Gout Suppressants - pharmacology | Thiazoles - pharmacology | Drug therapy | Gout | Cardiovascular disease | Heart attacks | Metabolites | Primary care | Urate oxidase | Crystals | Clinical trials | Data processing | Inflammation | Proximal tubules | Uric acid | Drug development | Kidney | Reviews | Interleukin 1 | Xanthine oxidase
Journal Article
Circulation, ISSN 0009-7322, 04/2004, Volume 109, Issue 14, pp. 1795 - 1801
Background - Isoforms of the NADPH oxidase contribute to vascular superoxide anion (.O-2(-)) formation and limit NO bioavailability. We hypothesized that the... 
Hypertension | Stress, oxidative | Angiotensin | Endothelium | endothelium | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | stress, oxidative | SUPEROXIDE-PRODUCTION | INVOLVEMENT | ANGIOTENSIN-II | DEFICIENT MICE | NAD(P)H OXIDASE | DISEASE | angiotensin | TETRAHYDROBIOPTERIN | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | hypertension | EXPRESSION | SMOOTH-MUSCLE CELLS | Angiotensin II - blood | Male | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt - pharmacology | Hypertension, Renovascular - physiopathology | Quinazolines | Endothelium, Vascular - enzymology | Glycoproteins - pharmacology | Cytochromes b - deficiency | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Superoxides - metabolism | Aorta | Indoles - pharmacology | Membrane Glycoproteins | Cardiomyopathy, Hypertrophic - etiology | Organ Culture Techniques | Disease Models, Animal | Polyethylene Glycols - pharmacology | NADPH Oxidases | Superoxide Dismutase - pharmacology | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Hypertension, Renovascular - enzymology | Mice, Inbred C57BL | Endothelium, Vascular - physiopathology | Enzyme Inhibitors - pharmacology | Protein Kinase C - antagonists & inhibitors | Tyrphostins - pharmacology | Antioxidants - pharmacology | NADPH Oxidase 2 | Mice, Knockout | Proto-Oncogene Proteins c-akt | Animals | Hypertension, Renovascular - complications | Bacterial Toxins - pharmacology | Cytochromes b - genetics | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Vasodilation - drug effects | Nitric Oxide - metabolism | Cytochromes b - physiology
Journal Article
Dental Materials, ISSN 0109-5641, 2012, Volume 28, Issue 5, pp. 561 - 572
Abstract Objectives Calcium and phosphate ion-releasing resin composites are promising for remineralization. However, there has been no report on incorporating... 
Advanced Basic Science | Dentistry | Quaternary ammonium salt | Streptococcus mutans biofilm | Stress-bearing | Amorphous calcium phosphate | Tooth caries inhibition | Silver nanoparticles | Antibacterial nanocomposite | STREPTOCOCCUS-MUTANS | MATERIALS SCIENCE, BIOMATERIALS | RESIN-COMPOSITES | POLYMERIZATION | MODEL | SHRINKAGE-STRESS | RESTORATIVE MATERIALS | DEMINERALIZATION | DENTAL COMPOSITES | SECONDARY CARIES | DENTISTRY, ORAL SURGERY & MEDICINE | GAP SIZE | Nanocomposites - chemistry | Nanoparticles - chemistry | Humans | Composite Resins - chemistry | Polyethylene Glycols - chemistry | Elastic Modulus | Methacrylates - chemistry | Composite Resins - pharmacology | Glass - chemistry | Quaternary Ammonium Compounds - chemistry | Bacterial Load - drug effects | Fluorides - chemistry | Anti-Bacterial Agents - chemistry | Methacrylates - pharmacology | Bacterial Adhesion - drug effects | Lactic Acid - analysis | Calcium Phosphates - pharmacology | Biofilms - drug effects | Bisphenol A-Glycidyl Methacrylate - chemistry | Microscopy, Electron, Transmission | Silver - pharmacology | Pliability | Microbial Viability - drug effects | Polyurethanes - chemistry | Silver - chemistry | Calcium Phosphates - chemistry | Materials Testing | Streptococcus mutans - drug effects | Polymethacrylic Acids - chemistry | Acrylic Resins - chemistry | Fluorides - pharmacology | Dental Materials - pharmacology | Dental Materials - chemistry | Anti-Bacterial Agents - pharmacology | Quaternary Ammonium Compounds - pharmacology | Phosphates | Nanoparticles | Biological products | Tissue engineering | Stem cells | Calcium phosphate | Antibacterial agents | silver nanoparticles | quaternary ammonium salt | tooth caries inhibition | amorphous calcium phosphate | stress-bearing
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 37, pp. 9877 - 9887
Abstract P-glycoprotein (P-gp) mediated drug efflux has been recognized as a key factor contributing to the multidrug resistance (MDR) in tumor cells. To... 
Advanced Basic Science | Dentistry | P-glycoprotein | pH-sensitive | Copolymer micelles | d-α-tocopheryl polyethylene glycol succinate | Hyaluronic acid | Multidrug resistance | D-α-tocopheryl polyethylene glycol succinate | PH-sensitive | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | SELF-ASSEMBLED NANOPARTICLES | D-alpha-tocopheryl polyethylene glycol succinate | DRUG-RESISTANCE | POLYMERIC MICELLES | CANCER | HYALURONIC-ACID | VITAMIN-E TPGS | IRON-OXIDE | IN-VITRO | INTRACELLULAR DELIVERY | TARGETED DELIVERY | Doxorubicin - therapeutic use | Histidine - pharmacology | Antibiotics, Antineoplastic - pharmacology | Drug Resistance, Multiple - drug effects | Humans | Vitamin E - analogs & derivatives | Delayed-Action Preparations - chemistry | Hyaluronic Acid - pharmacology | Polyethylene Glycols - chemistry | MCF-7 Cells | Delayed-Action Preparations - pharmacology | Micelles | Female | Vitamin E - chemistry | Doxorubicin - administration & dosage | Polyethylene Glycols - pharmacology | Hyaluronic Acid - chemistry | Breast Neoplasms - drug therapy | Antibiotics, Antineoplastic - administration & dosage | Animals | Antibiotics, Antineoplastic - therapeutic use | Mice, Nude | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Cell Line, Tumor | Mice, Inbred BALB C | Histidine - chemistry | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | Vitamin E - pharmacology | Drug resistance in microorganisms | Anthracyclines | Histidine | Hydrogen-ion concentration | Polyols | Polyethylene glycol
Journal Article