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Journal Article
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2012, Volume 8, Issue 1, pp. 71 - 80
Abstract The in vivo efficacy of doxorubicin (DOX)-loaded poly(γ-benzyl l -glutamate)- block -hyaluronan (PBLG23 - b -HYA10 )-based polymersomes (PolyDOX) was... 
Internal Medicine | Hyaluronan | Ehrlich ascites tumor (EAT) | Antitumor activity | Doxorubicin | Polymersomes | MEDICINE, RESEARCH & EXPERIMENTAL | BLOCK-COPOLYMERS | SOLID TUMORS | DRUG-DELIVERY | RECEPTOR | NANOSCIENCE & NANOTECHNOLOGY | VASCULAR-PERMEABILITY | CANCER | CARRIERS | PACLITAXEL | LIPOSOMAL DOXORUBICIN | ENDOCYTOSIS HARE | Doxorubicin - blood | Doxorubicin - therapeutic use | Drug Carriers - adverse effects | Hyaluronic Acid - therapeutic use | Nanoparticles - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Drug Carriers - administration & dosage | Polyglutamic Acid - administration & dosage | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Nanoparticles - adverse effects | Drug Carriers - chemistry | Polyglutamic Acid - analogs & derivatives | Antineoplastic Agents - adverse effects | Female | Hyaluronic Acid - blood | Hyaluronic Acid - adverse effects | Doxorubicin - administration & dosage | Endocytosis - immunology | Technetium - chemistry | Rabbits | Hyaluronic Acid - administration & dosage | Hyaluronic Acid - chemistry | Carcinoma, Ehrlich Tumor - drug therapy | Doxorubicin - chemical synthesis | Polyglutamic Acid - blood | Polyglutamic Acid - chemistry | Animals | Hyaluronic Acid - analogs & derivatives | Antineoplastic Agents - blood | Hyaluronan Receptors - immunology | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Polyglutamic Acid - therapeutic use | Neoplasms, Experimental - drug therapy | Doxorubicin - adverse effects | Polyglutamic Acid - adverse effects | Anthracyclines | Ascites | Hyaluronic acid | Tumors | Polymers | Chemical Sciences
Journal Article
Journal Article
INTERNATIONAL JOURNAL OF NANOMEDICINE, ISSN 1178-2013, 2017, Volume 12, pp. 6477 - 6486
Diabetic cerebral infarction is with poorer prognosis and high rates of mortality. Ginsenoside Rg1 (Rg1) has a wide variety of therapeutic values for central... 
blood-brain barrier | MIGRATION | poly-gamma-glutamic acid | ARTERY OCCLUSION | QUANTIFICATION | OX26 | NANOSCIENCE & NANOTECHNOLOGY | PROVIDES NEUROPROTECTION | DELIVERY | ENDOTHELIAL PROGENITOR CELLS | IN-VITRO | VASCULAR COMPLICATIONS | ginsenoside Rg1 | PHARMACOLOGY & PHARMACY | DYSFUNCTION | TRIPTOLIDE | Cerebral Infarction - drug therapy | Diabetes Mellitus, Experimental - drug therapy | Nanoparticles - chemistry | Male | Polyglutamic Acid - analogs & derivatives | Cerebral Infarction - physiopathology | Neuroprotective Agents - pharmacokinetics | Ginsenosides - administration & dosage | Diabetes Mellitus, Experimental - complications | Neuroprotective Agents - administration & dosage | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Brain - physiopathology | Blood-Brain Barrier - drug effects | Rats, Sprague-Dawley | Brain - drug effects | Particle Size | Polyglutamic Acid - chemistry | Animals | Receptors, Transferrin - immunology | Cerebral Infarction - etiology | Drug Liberation | Nanoparticles - administration & dosage | Drug Delivery Systems - methods | Dynamic Light Scattering | Ginsenosides - pharmacokinetics | Nanoparticles | Drug delivery systems | Diabetes | Ischemia | Hemodialysis | Molecular weight | blood brain barrier | transferrin receptor | Diabetic cerebral infarction | Ginsenoside Rg1 nanoparticle
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 03/2017, Volume 51, pp. 246 - 257
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 2015, Volume 71, Issue 4, pp. 411 - 423
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 2011, Volume 416, Issue 1, pp. 365 - 375
Poly(lactide- co-glycolide) (PLGA) nanoparticles (NPs) with surface poly-(γ-glutamic acid) (γ-PGA) were applied to enhance the transport of saquinavir (SQV)... 
Human brain-microvascular endothelial cell | Saquinavir | Human astrocyte | Poly-(γ-glutamic acid) | Poly(lactide- co-glycolide) | Blood–brain barrier | Blood-brain barrier | Poly(lactide-co-glycolide) | Poly-(gamma-glutamic acid) | POLY(GAMMA-GLUTAMIC ACID) | DRUG-DELIVERY | BIODEGRADABLE NANOPARTICLES | SULFOPROPYLMETHACRYLATE COPOLYMER NANOPARTICLES | SOLID LIPID NANOPARTICLES | PLIGA-BASED MICROPARTICLES | IN-VITRO | ELECTROPHORETIC MOBILITY | METHYLMETHACRYLATE-SULFOPROPYLMETHACRYLATE | PHARMACOLOGY & PHARMACY | INCREASED PERMEABILITY | Molecular Weight | Models, Chemical | Nanoparticles - chemistry | Coculture Techniques | Humans | Drug Carriers - chemistry | Polyglutamic Acid - analogs & derivatives | Polyglactin 910 - pharmacokinetics | Polyglutamic Acid - pharmacokinetics | Polyglutamic Acid - biosynthesis | Ornithine Decarboxylase - biosynthesis | Surface Properties | Biological Transport - drug effects | Polyglactin 910 - chemistry | Drug Carriers - metabolism | Saquinavir - chemistry | Drug Compounding - methods | Endothelial Cells - metabolism | Endocytosis - drug effects | Nanoparticles - ultrastructure | Solubility | Drug Carriers - chemical synthesis | Blood-Brain Barrier - metabolism | Particle Size | Polyglutamic Acid - chemistry | Saquinavir - pharmacokinetics | Astrocytes - metabolism | Antiviral agents | Amino acids | Glutamate | Endothelium
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 9, pp. 2801 - 2811
Abstract Complexing agents such as diethylene triamine pentaacetic acid (DTPA) are known to disrupt intestinal tight junctions and inhibit intestinal proteases... 
Advanced Basic Science | Dentistry | Proteolytic inhibition | Oral protein delivery | Molecular dynamic simulation | Complexing agent | Adherens junction | MATERIALS SCIENCE, BIOMATERIALS | ACID | ENGINEERING, BIOMEDICAL | CHITOSAN | RATS | PEPTIDE | AGENT | INJECTION | DRUGS | PH | Nanoparticles - chemistry | Rats, Wistar | Tomography, Emission-Computed, Single-Photon | Biological Availability | Tomography, X-Ray Computed | Insulin - blood | Spectroscopy, Fourier Transform Infrared | Diabetes Mellitus, Experimental - blood | Protease Inhibitors - pharmacology | Pentetic Acid - chemistry | Protective Agents - pharmacology | Injections, Subcutaneous | Chitosan - chemical synthesis | Insulin - pharmacology | Tissue Distribution - drug effects | Administration, Oral | Rats | Insulin - administration & dosage | Electric Impedance | Cell Adhesion - drug effects | Static Electricity | Polyglutamic Acid - chemical synthesis | Molecular Dynamics Simulation | Blood Glucose - drug effects | Particle Size | Polyglutamic Acid - chemistry | Animals | Chitosan - chemistry | Diabetes Mellitus, Experimental - pathology | Absorption - drug effects | Drug Delivery Systems - methods | Insulin - pharmacokinetics | Nanoparticles | Biological products | Surface active agents | Blood sugar | Proteases | Permeability | Polyamines | Glutamate | Insulin | Diabetes therapy
Journal Article
Biomaterials, ISSN 0142-9612, 2009, Volume 31, Issue 10, pp. 2882 - 2892
Journal Article