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Journal of Controlled Release, ISSN 0168-3659, 03/2012, Volume 158, Issue 3, pp. 470 - 478
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2017, Volume 259, pp. 76 - 82
PLGA nanotherapeutics though representing a most promising platform for targeted cancer therapy are confronted with low stability and insufficient tumor cell... 
Coating | PLGA nanoparticles | Nanomedicine | Lung cancer | Docetaxel | DOXORUBICIN | POLYMERIC MICELLES | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | VITAMIN-E TPGS | BREAST-CANCER | THERAPY | IN-VIVO | PHARMACOLOGY & PHARMACY | CLINICAL TRANSLATION | ANTICANCER DRUG-DELIVERY | PROTEIN DELIVERY | Hyaluronic Acid - therapeutic use | Lung Neoplasms - drug therapy | Drug Carriers - therapeutic use | Nanoparticles - chemistry | Humans | Lung Neoplasms - metabolism | Drug Carriers - administration & dosage | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Polyglycolic Acid - therapeutic use | Drug Carriers - chemistry | Lactic Acid - pharmacokinetics | Taxoids - therapeutic use | Nanoparticles - therapeutic use | Antineoplastic Agents - pharmacokinetics | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Taxoids - chemistry | A549 Cells | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Lactic Acid - chemistry | Hyaluronic Acid - chemistry | Antineoplastic Agents - chemistry | Hyaluronic Acid - pharmacokinetics | Taxoids - pharmacokinetics | Taxoids - administration & dosage | Animals | Polyglycolic Acid - pharmacokinetics | Tumor Burden - drug effects | Mice, Nude | Polyglycolic Acid - chemistry | Cell Line, Tumor | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Lactic Acid - therapeutic use | Antimitotic agents | Chemotherapy | Antineoplastic agents | Hyaluronic acid | Cancer
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 05/2017, Volume 523, Issue 1, pp. 300 - 309
Metastasis impedes the successful chemotherapy for breast cancer. In this study, an Akt inhibitor (quercetin, Qu) was co-delivered with a chemotherapeutic... 
Metastasis docetaxel | Breast cancer | Akt/MMP-9 pathway | Hyaluronic acid | Quercetin | MMP-9 EXPRESSION | TARGETED DRUG-DELIVERY | POLYMERIC MICELLES | CELLULAR UPTAKE | COLON-CANCER | TUMOR XENOGRAFTS | IN-VIVO | COMBINATION CHEMOTHERAPY | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | PI3K/AKT SIGNALING PATHWAY | Alct/MMP-9 pathway | Polyethylenes - administration & dosage | Antioxidants - chemistry | Nanoparticles - chemistry | Apoptosis - drug effects | Matrix Metalloproteinase Inhibitors - administration & dosage | Matrix Metalloproteinase Inhibitors - pharmacokinetics | Antineoplastic Agents - administration & dosage | Breast Neoplasms | Polyethylenes - pharmacokinetics | Lactic Acid - pharmacokinetics | Matrix Metalloproteinase 9 - metabolism | Quercetin - pharmacokinetics | Imines - chemistry | Quercetin - administration & dosage | Female | Antineoplastic Agents - pharmacokinetics | Proto-Oncogene Proteins c-akt - metabolism | Lactic Acid - administration & dosage | Polyethylenes - chemistry | Wound Healing - drug effects | Imines - administration & dosage | Polyglycolic Acid - administration & dosage | Taxoids - chemistry | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Lactic Acid - chemistry | Quercetin - chemistry | Hyaluronic Acid - chemistry | Matrix Metalloproteinase Inhibitors - chemistry | Antineoplastic Agents - chemistry | Hyaluronic Acid - pharmacokinetics | Imines - pharmacokinetics | Taxoids - pharmacokinetics | Cell Movement - drug effects | Taxoids - administration & dosage | Animals | Polyglycolic Acid - pharmacokinetics | Polyglycolic Acid - chemistry | Antioxidants - administration & dosage | Cell Line, Tumor | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Antioxidants - pharmacokinetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Nanoparticles | Chemotherapy | Cancer cells | Metastasis | Cancer
Journal Article
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 11/2012, Volume 109, Issue 11, pp. 2920 - 2931
Journal Article
Journal Article
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 01/2016, Volume 29, pp. 248 - 260
Despite advances in polymeric nanoparticles (NPs) as effective delivery systems for anticancer drugs, rapid clearance from blood and poor penetration capacity... 
Interstitial penetration | Dual coating | Polymeric nanoparticles | Chitosan oligosaccharide | Poly (ethylene glycol)-poly (d,l-lactic acid) (PEG-PDLLA) | Tumor accumulation | CORE NANOPARTICLES | DRUG | MATERIALS SCIENCE, BIOMATERIALS | DEEP PENETRATION | ENGINEERING, BIOMEDICAL | DELIVERY-SYSTEMS | BIOLOGICAL-ACTIVITIES | PEG CHAIN-LENGTH | SURFACE-CHARGE | Poly (ethylene glycol)-poly (D,L-lactic acid) (PEG-PDLLA) | IN-VITRO | CATIONIC NANOPARTICLES | Nanoparticles - chemistry | Humans | Polyglycolic Acid - pharmacology | Polyethylene Glycols - chemistry | Breast Neoplasms - metabolism | Oligosaccharides - pharmacology | Lactic Acid - pharmacokinetics | Oligosaccharides - chemistry | Chitosan - pharmacology | Polyesters | Female | Lactic Acid - pharmacology | Polyethylene Glycols - pharmacology | Oligosaccharides - pharmacokinetics | Lactic Acid - chemistry | Polyethylene Glycols - pharmacokinetics | Breast Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Chitosan - chemistry | Polyglycolic Acid - pharmacokinetics | Breast Neoplasms - pathology | Chitosan - pharmacokinetics | Mice, Nude | Polyglycolic Acid - chemistry | Polymers - pharmacokinetics | Polymers - pharmacology | Cell Line, Tumor | Polymers - chemistry | Mice | Mice, Inbred BALB C | Lactic acid | Coatings | Polyethylene glycol | Tumors | Drugs | Nanoparticles | Yuan (China) | Drug delivery systems | Nanotechnology | Vehicles | Penetration | Cationic | Interstitials | Charge | Coating | Oligosaccharides
Journal Article
Annals of Biomedical Engineering, ISSN 0090-6964, 1/2017, Volume 45, Issue 1, pp. 297 - 305
Controlled drug delivery systems, that include sequential and/or sustained drug delivery, have been utilized to enhance the therapeutic effects of many current... 
Biomedicine, general | Biomedical Engineering | Biochemistry, general | Controlled delivery | Biomedicine | PLGA | Composite materials | Classical Mechanics | Differential delivery | Alginate | Biological and Medical Physics, Biophysics | Extrusion printing | SYSTEM | ENGINEERING, BIOMEDICAL | TISSUE | RELEASE PROFILES | TABLETS | MATRICES | BONE REGENERATION | MULTIPLE-DRUGS | Alginates - pharmacology | Fluorescent Dyes - chemistry | Fluorescent Dyes - pharmacokinetics | Lactic Acid - chemistry | Humans | Polyglycolic Acid - pharmacology | Delayed-Action Preparations - chemistry | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Hexuronic Acids - pharmacokinetics | Lactic Acid - pharmacokinetics | Glucuronic Acid - pharmacology | Polyglycolic Acid - pharmacokinetics | Alginates - chemistry | Delayed-Action Preparations - pharmacology | Polyglycolic Acid - chemistry | Delayed-Action Preparations - pharmacokinetics | HEK293 Cells | Fluorescent Dyes - pharmacology | Glucuronic Acid - chemistry | Lactic Acid - pharmacology | Printing, Three-Dimensional | Alginates - pharmacokinetics | Hexuronic Acids - pharmacology | Drugs | Proteins | Drug delivery systems | Pharmacy | Therapeutics | Stem cells | Computer-aided design | 3D printing | Homeopathy | Materia medica and therapeutics | Vehicles | Biomedical engineering | Sequential delivery | Toxicity | Control systems | Tubes | Devices | Controlled Delivery | Differential Delivery | Composite Materials
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2012, Volume 157, Issue 1, pp. 149 - 159
Journal Article
by Mu, L and Feng, S.S
Journal of Controlled Release, ISSN 0168-3659, 01/2003, Volume 86, Issue 1, pp. 33 - 48
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2007, Volume 122, Issue 1, pp. 1 - 9
Journal Article