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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 28, pp. 10287 - 10292
Bone is a favorable microenvironment for tumor growth and a frequent destination for metastatic cancer cells. Targeting cancers within the bone marrow remains... 
Nanoparticles | Femur | Emulsions | Antineoplastics | Multiple myeloma | Fluorescence | Bones | Pretreatment | Polymers | Cancer | Alendronate-PLGA-PEG | Targeting nanomedicine | Bisphosphonate | Bone metastasis | MULTIPLE-MYELOMA | CELLS | DEXAMETHASONE | ACTIVATION | bone metastasis | VIVO | MULTIDISCIPLINARY SCIENCES | BORTEZOMIB | ANTITUMOR-ACTIVITY | targeting nanomedicine | IN-VITRO | THERAPY | PATHWAY | alendronate-PLGA-PEG | bisphosphonate | Neoplasm Transplantation | Polyglycolic Acid - chemical synthesis | Nanoparticles - chemistry | Humans | Polyglycolic Acid - pharmacology | Polyethylene Glycols - chemistry | Boronic Acids - chemistry | Bone Neoplasms - pathology | Alendronate - chemistry | Bone Neoplasms - metabolism | Drug Delivery Systems | Neoplasms, Experimental - pathology | Multiple Myeloma - drug therapy | Heterografts | Antineoplastic Agents - pharmacology | Bone Neoplasms - drug therapy | Lactic Acid - pharmacology | Tumor Microenvironment - drug effects | Bortezomib | Lactic Acid - chemistry | Nanoparticles - ultrastructure | Polyethylene Glycols - pharmacokinetics | Antineoplastic Agents - chemistry | Multiple Myeloma - metabolism | Xenograft Model Antitumor Assays | Pyrazines - chemistry | Multiple Myeloma - pathology | Animals | Mice, Nude | Polyglycolic Acid - chemistry | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Polyethylene Glycols - chemical synthesis | Lactic Acid - chemical synthesis | Neoplasms, Experimental - metabolism | Pyrazines - pharmacology | Neoplasms, Experimental - drug therapy | Boronic Acids - pharmacology | Index Medicus | Biological Sciences | Physical Sciences
Journal Article
Biomaterials, ISSN 0142-9612, 2008, Volume 30, Issue 8, pp. 1627 - 1634
Journal Article
Journal Article
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 01/2016, Volume 29, pp. 248 - 260
Despite advances in polymeric nanoparticles (NPs) as effective delivery systems for anticancer drugs, rapid clearance from blood and poor penetration capacity... 
Interstitial penetration | Dual coating | Polymeric nanoparticles | Chitosan oligosaccharide | Poly (ethylene glycol)-poly (d,l-lactic acid) (PEG-PDLLA) | Tumor accumulation | CORE NANOPARTICLES | DRUG | MATERIALS SCIENCE, BIOMATERIALS | DEEP PENETRATION | ENGINEERING, BIOMEDICAL | DELIVERY-SYSTEMS | BIOLOGICAL-ACTIVITIES | PEG CHAIN-LENGTH | SURFACE-CHARGE | Poly (ethylene glycol)-poly (D,L-lactic acid) (PEG-PDLLA) | IN-VITRO | CATIONIC NANOPARTICLES | Nanoparticles - chemistry | Humans | Polyglycolic Acid - pharmacology | Polyethylene Glycols - chemistry | Breast Neoplasms - metabolism | Oligosaccharides - pharmacology | Lactic Acid - pharmacokinetics | Oligosaccharides - chemistry | Chitosan - pharmacology | Polyesters | Female | Lactic Acid - pharmacology | Polyethylene Glycols - pharmacology | Oligosaccharides - pharmacokinetics | Lactic Acid - chemistry | Polyethylene Glycols - pharmacokinetics | Breast Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Chitosan - chemistry | Polyglycolic Acid - pharmacokinetics | Breast Neoplasms - pathology | Chitosan - pharmacokinetics | Mice, Nude | Polyglycolic Acid - chemistry | Polymers - pharmacokinetics | Polymers - pharmacology | Cell Line, Tumor | Polymers - chemistry | Mice | Mice, Inbred BALB C | Lactic acid | Coatings | Polyethylene glycol | Tumors | Drugs | Nanoparticles | Yuan (China) | Drug delivery systems | Nanotechnology | Vehicles | Penetration | Cationic | Interstitials | Charge | Coating | Oligosaccharides
Journal Article
Journal Article
Annals of Biomedical Engineering, ISSN 0090-6964, 1/2017, Volume 45, Issue 1, pp. 297 - 305
Controlled drug delivery systems, that include sequential and/or sustained drug delivery, have been utilized to enhance the therapeutic effects of many current... 
Biomedicine, general | Biomedical Engineering | Biochemistry, general | Controlled delivery | Biomedicine | PLGA | Composite materials | Classical Mechanics | Differential delivery | Alginate | Biological and Medical Physics, Biophysics | Extrusion printing | SYSTEM | ENGINEERING, BIOMEDICAL | TISSUE | RELEASE PROFILES | TABLETS | MATRICES | BONE REGENERATION | MULTIPLE-DRUGS | Alginates - pharmacology | Fluorescent Dyes - chemistry | Fluorescent Dyes - pharmacokinetics | Lactic Acid - chemistry | Humans | Polyglycolic Acid - pharmacology | Delayed-Action Preparations - chemistry | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Hexuronic Acids - pharmacokinetics | Lactic Acid - pharmacokinetics | Glucuronic Acid - pharmacology | Polyglycolic Acid - pharmacokinetics | Alginates - chemistry | Delayed-Action Preparations - pharmacology | Polyglycolic Acid - chemistry | Delayed-Action Preparations - pharmacokinetics | HEK293 Cells | Fluorescent Dyes - pharmacology | Glucuronic Acid - chemistry | Lactic Acid - pharmacology | Printing, Three-Dimensional | Alginates - pharmacokinetics | Hexuronic Acids - pharmacology | Drugs | Proteins | Drug delivery systems | Pharmacy | Therapeutics | Stem cells | Computer-aided design | 3D printing | Homeopathy | Materia medica and therapeutics | Vehicles | Biomedical engineering | Sequential delivery | Toxicity | Control systems | Tubes | Devices | Controlled Delivery | Differential Delivery | Composite Materials
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 35, Issue 6, pp. 1932 - 1943
Journal Article
Biomaterials, ISSN 0142-9612, 2006, Volume 27, Issue 28, pp. 4894 - 4903
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2012, Volume 441, Issue 3, pp. 813 - 821
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 03/2016, Volume 225, pp. 230 - 239
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 09/2017, Volume 60, pp. 244 - 255
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2009, Volume 106, Issue 3, pp. 870 - 875
Journal Article