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Nature chemical biology, ISSN 1552-4469, 08/2015, Volume 11, Issue 9, pp. 705 - 712
Actin-targeting macrolides comprise a large, structurally diverse group of cytotoxins isolated from remarkably dissimilar micro- and macroorganisms. In spite... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cyanobacteria - genetics | Deltaproteobacteria - metabolism | Multigene Family | Peptides | Actins - metabolism | Bacterial Proteins - chemistry | Cyanobacteria - metabolism | Molecular Sequence Data | Polyketides - chemistry | Small Molecule Libraries - metabolism | Polyketides - metabolism | Polyketide Synthases - metabolism | Macrolides - chemistry | Pyrans - chemistry | Pyrans - metabolism | Base Sequence | Actins - chemistry | Symbiosis | Gene Expression | Bacterial Proteins - genetics | Macrolides - metabolism | Biological Evolution | Small Molecule Libraries - chemistry | Polyketide Synthases - chemistry | Animals | Deltaproteobacteria - genetics | Theonella - microbiology | Protein Binding | Bacterial Proteins - metabolism | Polyketide Synthases - genetics | Enzymes | Bacteria | Biosynthesis | Metabolism | Index Medicus | Polyketide Synthases/metabolism | Actins/metabolism | Macrolides/chemistry | Polyketide Synthases/chemistry | Life Sciences | Cyanobacteria/metabolism | Deltaproteobacteria/genetics | Bacterial Proteins/chemistry | Macrolides/metabolism | Actins/chemistry | Polyketide Synthases/genetics | Deltaproteobacteria/metabolism | Small Molecule Libraries/metabolism | Theonella/microbiology | Cyanobacteria/genetics | Pyrans/metabolism | Small Molecule Libraries/chemistry | Microbiology and Parasitology | Bacterial Proteins/metabolism | Polyketides/chemistry | Polyketides/metabolism | Bacterial Proteins/genetics | Pyrans/chemistry
Journal Article
Journal Article
Journal of organic chemistry, ISSN 0022-3263, 11/2012, Volume 77, Issue 22, pp. 9933 - 9953
Journal Article
Biochemistry (Easton), ISSN 0006-2960, 12/2014, Volume 53, Issue 49, pp. 7854 - 7865
Lactimidomycin (LTM, 1) and iso-migrastatin (iso-MGS, 2) belong to the glutarimide-containing polyketide family of natural products. We previously cloned and... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Multigene Family | Macrolides - isolation & purification | Antibiotics, Antineoplastic - pharmacology | Stereoisomerism | Humans | Bacterial Proteins - chemistry | Molecular Sequence Data | Polyketides - chemistry | Antibiotics, Antineoplastic - isolation & purification | Structure-Activity Relationship | Polyketides - metabolism | Polyketide Synthases - metabolism | Antibiotics, Antineoplastic - chemistry | Macrolides - chemistry | Base Sequence | Drug Design | Protein Engineering | Macrolides - pharmacology | Molecular Structure | Piperidones - isolation & purification | Recombinant Proteins - metabolism | Bacterial Proteins - antagonists & inhibitors | Cell Survival - drug effects | Polyketide Synthases - antagonists & inhibitors | Streptomyces - genetics | Bacterial Proteins - genetics | Gene Silencing | Antibiotics, Antineoplastic - biosynthesis | Recombinant Proteins - chemistry | Mutant Proteins - metabolism | Macrolides - metabolism | Piperidones - pharmacology | Neoplasms - drug therapy | Piperidones - chemistry | Polyketide Synthases - chemistry | Bioreactors | Models, Biological | Mutant Proteins - chemistry | Polyketides - isolation & purification | Cell Line, Tumor | Bacterial Proteins - metabolism | Streptomyces - enzymology | Piperidones - metabolism | Polyketide Synthases - genetics | Polyketides - pharmacology | Streptomyces | Physiological aspects | Biosynthesis | Analysis | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 10/2011, Volume 286, Issue 41, pp. 35562 - 35570
Journal Article