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Nature Chemical Biology, ISSN 1552-4450, 09/2015, Volume 11, Issue 9, pp. 705 - 712
Actin-targeting macrolides comprise a large, structurally diverse group of cytotoxins isolated from remarkably dissimilar micro- and macroorganisms. In spite... 
BACTERIAL SYMBIONT | GENE-CLUSTER | CYTOTOXIC MACROLIDES | NATURAL-PRODUCT DISCOVERY | CYANOBACTERIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNTHASES | IN-SITU HYBRIDIZATION | SPONGE THEONELLA-SWINHOEI | IDENTIFICATION | ANTIFUNGAL MACROLIDE | Cyanobacteria - genetics | Deltaproteobacteria - metabolism | Multigene Family | Peptides | Actins - metabolism | Bacterial Proteins - chemistry | Cyanobacteria - metabolism | Molecular Sequence Data | Polyketides - chemistry | Small Molecule Libraries - metabolism | Polyketides - metabolism | Polyketide Synthases - metabolism | Macrolides - chemistry | Pyrans - chemistry | Pyrans - metabolism | Base Sequence | Actins - chemistry | Symbiosis | Gene Expression | Bacterial Proteins - genetics | Macrolides - metabolism | Biological Evolution | Small Molecule Libraries - chemistry | Polyketide Synthases - chemistry | Animals | Deltaproteobacteria - genetics | Theonella - microbiology | Protein Binding | Bacterial Proteins - metabolism | Polyketide Synthases - genetics | Enzymes | Bacteria | Biosynthesis | Metabolism | Polyketide Synthases/metabolism | Actins/metabolism | Macrolides/chemistry | Polyketide Synthases/chemistry | Life Sciences | Cyanobacteria/metabolism | Deltaproteobacteria/genetics | Bacterial Proteins/chemistry | Macrolides/metabolism | Actins/chemistry | Polyketide Synthases/genetics | Deltaproteobacteria/metabolism | Small Molecule Libraries/metabolism | Theonella/microbiology | Cyanobacteria/genetics | Pyrans/metabolism | Small Molecule Libraries/chemistry | Microbiology and Parasitology | Bacterial Proteins/metabolism | Polyketides/chemistry | Polyketides/metabolism | Bacterial Proteins/genetics | Pyrans/chemistry
Journal Article
Science, ISSN 0036-8075, 10/2009, Volume 326, Issue 5952, pp. 589 - 592
Journal Article
The Plant Cell, ISSN 1040-4651, 9/2004, Volume 16, Issue 9, pp. 2499 - 2513
Isolates of the rice blast fungus Magnaporthe grisea that carry the gene encoding Avirulence Conferring Enzyme1 (ACE1) are specifically recognized by rice... 
Enzymes | Barley | Pathogens | Reverse transcriptase polymerase chain reaction | Introns | Genomics | Genes | Biosynthesis | Genomes | Rice | BIOCHEMISTRY & MOLECULAR BIOLOGY | III EFFECTOR | CLADOSPORIUM-FULVUM | ELICITOR PROTEINS | PLANT SCIENCES | CELL BIOLOGY | BIOSYNTHETIC GENE-CLUSTER | GENOME SEQUENCE | HOST-SELECTIVE TOXINS | BLAST FUNGUS | MOLECULAR-CLONING | ADENYLATION DOMAINS | AVIRULENCE GENE | Magnaporthe - enzymology | DNA, Complementary - genetics | Immunity, Innate - genetics | Molecular Sequence Data | Peptide Synthases - isolation & purification | Amino Acid Sequence - genetics | Phylogeny | Recombinant Fusion Proteins - metabolism | Peptide Synthases - genetics | Polyketide Synthases - metabolism | Oryza - genetics | Oryza - microbiology | Plant Diseases - genetics | Cytoplasm - genetics | Gene Expression Regulation, Fungal - genetics | Fungal Proteins - isolation & purification | Plant Leaves - enzymology | Magnaporthe - genetics | DNA, Complementary - analysis | Cytoplasm - enzymology | Base Sequence - genetics | Signal Transduction - genetics | Fungal Proteins - genetics | Oryza - enzymology | Macromolecular Substances | Peptide Synthases - metabolism | Polyketide Synthases - isolation & purification | Plant Leaves - genetics | Recombinant Fusion Proteins - genetics | Polyketide Synthases - genetics | Fungal Proteins - metabolism | Genetic aspects | Pathogenic microorganisms | Research | Structure | Plant immunology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2009, Volume 106, Issue 34, pp. 14558 - 14563
Fungi produce numerous low molecular weight molecules endowed with a multitude of biological activities. However, mining the fullgenome sequences of fungi... 
Fungi | Polyketides | Lichens | Microorganisms | Metabolites | RNA | Genes | Coculture techniques | Multigene family | Biosynthesis | Streptomyces | Lecanoric acid | Orsellinic acid | Genome mining | ANTIBIOTICS | ACID | lecanoric acid | MULTIDISCIPLINARY SCIENCES | SYNTHASE GENES | SECONDARY METABOLOME | DISCOVERY | orsellinic acid | PROTEINS | EXPRESSION | genome mining | ZEARALENONE | Aspergillus nidulans - genetics | Oligonucleotide Array Sequence Analysis | Mycelium - ultrastructure | Gene Expression Profiling | Chromatography, High Pressure Liquid | Phylogeny | Aspergillus nidulans - metabolism | Salicylates - chemistry | Mycelium - metabolism | Polyketide Synthases - metabolism | Ecosystem | Salicylates - analysis | Molecular Structure | Actinobacteria - physiology | Gene Expression Regulation, Fungal | Microscopy, Electron, Scanning | Polyketide Synthases - classification | Actinobacteria - ultrastructure | Zearalenone - chemistry | Actinobacteria - classification | Fungal Proteins - genetics | Macrolides - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Aspergillus nidulans - ultrastructure | Blotting, Northern | Genome, Fungal - genetics | Zearalenone - metabolism | Mutation | Polyketide Synthases - genetics | Mycelium - genetics | Fungal Proteins - metabolism | Physiological aspects | Microbiological synthesis | Aspergillus | Genetic aspects | Research | Cathepsin K | Gene clusters | Mycelia | Electron microscopy | polyketides | Mining | Polyketide synthase | Polymerase chain reaction | Secondary metabolites | Mycobionts | Actinomycetes | Dialysis | Models | Communication | Biological Sciences
Journal Article