Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2478) 2478
Publication (235) 235
Book Chapter (7) 7
Book Review (7) 7
Conference Proceeding (5) 5
Data Set (1) 1
Magazine Article (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1498) 1498
polylysine - pharmacology (1222) 1222
humans (961) 961
polylysine - chemistry (642) 642
index medicus (612) 612
mice (548) 548
pharmacology & pharmacy (486) 486
biochemistry & molecular biology (416) 416
rats (415) 415
polylysine (393) 393
male (332) 332
cells, cultured (299) 299
peptides - pharmacology (277) 277
polylysine - analogs & derivatives (272) 272
female (271) 271
kinetics (255) 255
cell line (245) 245
polylysine - metabolism (224) 224
cells (190) 190
transfection (184) 184
chemistry, multidisciplinary (181) 181
cell survival - drug effects (173) 173
materials science, biomaterials (172) 172
molecular weight (169) 169
expression (164) 164
in-vitro (164) 164
delivery (159) 159
poly-l-lysine (157) 157
time factors (157) 157
gene transfer techniques (150) 150
hydrogen-ion concentration (149) 149
nanoparticles (149) 149
cell line, tumor (148) 148
in-vivo (148) 148
cell biology (146) 146
lysine (135) 135
polyethylene glycols - chemistry (135) 135
polylysine - administration & dosage (132) 132
dna (131) 131
dose-response relationship, drug (130) 130
cattle (129) 129
drug delivery systems (129) 129
particle size (128) 128
gene delivery (127) 127
biotechnology & applied microbiology (123) 123
in vitro techniques (123) 123
molecular sequence data (123) 123
engineering, biomedical (122) 122
phosphorylation (120) 120
biophysics (118) 118
peptides (117) 117
mice, inbred balb c (114) 114
poly (112) 112
proteins (111) 111
surface properties (111) 111
amino acid sequence (108) 108
cell adhesion - drug effects (105) 105
tumor cells, cultured (105) 105
poly i-c - pharmacology (104) 104
rats, sprague-dawley (103) 103
research article (100) 100
polymers (99) 99
immunology (98) 98
medicine, research & experimental (95) 95
therapy (93) 93
rabbits (91) 91
research (91) 91
plasmid dna (90) 90
article (89) 89
dna - chemistry (89) 89
carboxymethylcellulose sodium - pharmacology (88) 88
polymers - chemistry (88) 88
cell adhesion (87) 87
analysis (84) 84
protamines - pharmacology (84) 84
binding (83) 83
cell proliferation - drug effects (82) 82
nanoparticles - chemistry (81) 81
peptides - chemistry (81) 81
heparin - pharmacology (80) 80
protein binding (80) 80
cell differentiation - drug effects (79) 79
drug carriers (79) 79
drug-delivery (79) 79
cancer (78) 78
gene therapy (77) 77
neurosciences (77) 77
transfection - methods (76) 76
endocytosis (75) 75
anti-bacterial agents - pharmacology (74) 74
dna - administration & dosage (74) 74
drug carriers - chemistry (74) 74
liposomes (74) 74
cations (73) 73
dna - metabolism (73) 73
polymer science (73) 73
hela cells (72) 72
structure-activity relationship (71) 71
capsules (70) 70
gene expression (70) 70
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2440) 2440
Russian (15) 15
Chinese (13) 13
Japanese (6) 6
French (3) 3
Spanish (2) 2
German (1) 1
Italian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text The key role of the scaffold on the efficiency of dendrimer nanodrugs
by Caminade, Anne-Marie and Fruchon, Severine and Turrin, Cedric-Olivier and Poupot, Mary and Ouali, Armelle and Maraval, Alexandrine and Garzoni, Matteo and Maly, Marek and Furer, Victor L and Kovalenko, Valeri and Majoral, Jean-Pierre and Pavan, Giovanni M and Poupot, Remy
Nature Communications, ISSN 2041-1723, 07/2015, Volume 6, Issue 1, p. 7722
Dendrimers are well-defined macromolecules whose highly branched structure is reminiscent of many natural structures, such as trees, dendritic cells, neurons... 
CELLS | NANOPARTICLES | ACTIVATION | DESIGN | RECOGNITION | MULTIDISCIPLINARY SCIENCES | MONOCYTES | PHOSPHORUS-CONTAINING DENDRIMERS | Polylysine - pharmacology | Silanes - chemistry | Nanoparticles - chemistry | Biocompatible Materials - chemistry | Humans | Aza Compounds - chemistry | Polylysine - chemistry | Aza Compounds - pharmacology | Biocompatible Materials - pharmacology | Polypropylenes - pharmacology | Molecular Dynamics Simulation | Bone Density Conservation Agents - pharmacology | Monocytes - drug effects | Flow Cytometry | Diphosphonates - chemistry | Dendrimers - chemistry | Polypropylenes - chemistry | Molecular Structure | Dendrimers - pharmacology | Silanes - pharmacology | Diphosphonates - pharmacology | Bone Density Conservation Agents - chemistry | Chemical Sciences | Coordination chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text pH-responsive, lysine-based hydrogels for the oral delivery of a wide size range of molecules
by Watkins, Kira A and Chen, Rongjun
International Journal of Pharmaceutics, ISSN 0378-5173, 01/2015, Volume 478, Issue 2, pp. 496 - 503
Hydrogels synthesized from poly( -lysine isophthalamide) (PLP) crosslinked with -lysine methyl ester were investigated as drug delivery systems for a wide size... 
Oral drug delivery | Amphiphilic | Hydrogels | pH-responsive | Controlled release | COMPLEXATION HYDROGELS | TRANSIT | DESIGN | DRUG-DELIVERY | DOSAGE FORMS | INSULIN | NANOPARTICLES | IN-VITRO | PSEUDO-PEPTIDES | SYSTEMS | PHARMACOLOGY & PHARMACY | Hemolysis - drug effects | Phthalic Acids - chemistry | Dextrans - chemistry | Polylysine - chemistry | Fluorescein-5-isothiocyanate - chemistry | Dextrans - pharmacology | Phthalic Acids - pharmacology | Fluorescein - chemistry | Lysine - analogs & derivatives | Polylysine - pharmacology | Fluorescein-5-isothiocyanate - pharmacology | Administration, Oral | Fluorescein-5-isothiocyanate - analogs & derivatives | Peptide Hydrolases - chemistry | Erythrocytes - drug effects | Animals | Lysine - pharmacology | Fluorescein - pharmacology | Polymers - pharmacology | Drug Liberation | Polymers - chemistry | Sheep | Hydrogels - pharmacology | Lysine - chemistry | Hydrogels - chemistry | Hydrogen-Ion Concentration | Lysine
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Effective Gene Delivery Using Stimulus-Responsive Catiomer Designed with Redox-Sensitive Disulfide and Acid-Labile Imine Linkers
by Cai, Xiaojun and Dong, Chunyan and Dong, Haiqing and Wang, Gangmin and Pauletti, Giovanni M and Pan, Xiaojing and Wen, Huiyun and Mehl, Isaac and Li, Yongyong and Shi, Donglu
Biomacromolecules, ISSN 1525-7797, 04/2012, Volume 13, Issue 4, pp. 1024 - 1034
A dual stimulus-responsive mPEG-SS-PLL15-glutaraldehyde star (mPEG-SS-PLL15-star) catiomer is developed and biologically evaluated. The catiomer system... 
DRUG | POLYMERS | POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | LOW-MOLECULAR-WEIGHT | TRANSFECTION EFFICIENCY | CHEMISTRY, ORGANIC | MICELLES | POLYMERIZATION | POLYETHYLENIMINE | BLOCK-COPOLYMER | DNA POLYPLEXES | Cross-Linking Reagents - pharmacology | Humans | Polyethylene Glycols - chemistry | Polylysine - chemistry | Cross-Linking Reagents - chemical synthesis | Cations - pharmacology | Disulfides - chemistry | Surface Properties | HEK293 Cells | Imines - chemistry | Disulfides - pharmacology | Molecular Structure | Glutaral - chemistry | Polyethylene Glycols - pharmacology | Cations - chemical synthesis | Cell Survival - drug effects | Gene Transfer Techniques | Cations - chemistry | Cross-Linking Reagents - chemistry | Genetic Vectors - chemistry | Oxidation-Reduction | Genetic Vectors - chemical synthesis | Imines - pharmacology | Polylysine - genetics | Particle Size | Genetic Vectors - pharmacology | Glutaral - pharmacology | HeLa Cells
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Multifunctional hydrogel-based scaffold for improving the functionality of encapsulated therapeutic cells and reducing inflammatory response
by Acarregui, Argia and Herrån, Enara and Igartua, Manoli and Blanco, Francisco Javier and Pedraz, José Luis and Orive, Gorka and Hernandez, Rosa Maria
Acta Biomaterialia, ISSN 1742-7061, 10/2014, Volume 10, Issue 10, pp. 4206 - 4216
Since the introduction of cell immunoisolation as an alternative to protect transplanted cells from host immune attack, much effort has been made to develop... 
Poly(lactic-co-glycolic) acid | Dexamethasone | Alginate Hydrogel-based scaffolds | Cell encapsulation | Xenotransplantation | DRUG | PORCINE SERTOLI-CELLS | STEM-CELLS | MATERIALS SCIENCE, BIOMATERIALS | PLGA-MICROSPHERES | ENGINEERING, BIOMEDICAL | RELEASE | ALGINATE MICROCAPSULES | DELIVERY | FOREIGN-BODY RESPONSE | TISSUE-RESPONSE | Dexamethasone - chemistry | Inflammation - pathology | Polylysine - analogs & derivatives | Capsules - pharmacology | Rats, Inbred F344 | Polyglycolic Acid - pharmacology | Delayed-Action Preparations - chemistry | Male | Polylysine - chemistry | Microspheres | Inflammation - metabolism | Dexamethasone - pharmacology | Delayed-Action Preparations - pharmacology | Cells, Immobilized - transplantation | Lactic Acid - pharmacology | Alginates - pharmacology | Cell Line | Polylysine - pharmacology | Lactic Acid - chemistry | Anti-Inflammatory Agents - pharmacology | Cells, Immobilized - metabolism | Rats | Capsules - chemistry | Cell Transplantation | Animals | Anti-Inflammatory Agents - chemistry | Alginates - chemistry | Polyglycolic Acid - chemistry | Inflammation - prevention & control | Mice | Hydrogels - pharmacology | Hydrogels - chemistry | Surgical implants | Hydrogels | Implantation | Constants | Inflammatory response | Alginates | Proposals | Scaffolds
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Synergistic Effect of Nod1 and Nod2 Agonists with Toll-Like Receptor Agonists on Human Dendritic Cells To Generate Interleukin-12 and T Helper Type 1 Cells
by Hiroyuki Tada and Setsuya Aiba and Ken-Ichiro Shibata and Toshiaki Ohteki and Haruhiko Takada
Infection and Immunity, ISSN 0019-9567, 12/2005, Volume 73, Issue 12, pp. 7967 - 7976
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
INFECTIOUS DISEASES | HUMAN MONOCYTIC CELLS | LIPOTEICHOIC ACID | MURAMYL DIPEPTIDE | HOST RECOGNITION | WALL COMPONENTS | IFN-GAMMA | ADJUVANT ACTIVITY | DIAMINOPIMELIC ACID | IMMUNOLOGY | BACTERIAL PEPTIDOGLYCAN | CUTTING EDGE | Adjuvants, Immunologic - pharmacology | Diaminopimelic Acid - pharmacology | Dendritic Cells - immunology | Humans | RNA, Messenger - analysis | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | Th1 Cells - immunology | Th1 Cells - metabolism | Dendritic Cells - drug effects | Toll-Like Receptors - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Polylysine - pharmacology | Poly I-C - pharmacology | Cytokines - metabolism | Interleukin-12 - metabolism | Nod2 Signaling Adaptor Protein | Adaptor Proteins, Signal Transducing - agonists | Toll-Like Receptors - agonists | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | Drug Synergism | Diaminopimelic Acid - analogs & derivatives | Intracellular Signaling Peptides and Proteins - agonists | Toll-Like Receptors - genetics | Adaptor Proteins, Signal Transducing - genetics | Lipid A - pharmacology | Nod1 Signaling Adaptor Protein | Adaptor Proteins, Signal Transducing - metabolism | Oligodeoxyribonucleotides - pharmacology | Oligopeptides - pharmacology | Host Response and Inflammation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Nanogel-Conjugated Reverse Transcriptase Inhibitors and Their Combinations as Novel Antiviral Agents with Increased Efficacy against HIV‑1 Infection
by Senanayake, T. H and Gorantla, S and Makarov, E and Lu, Y and Warren, G and Vinogradov, S. V
Molecular Pharmaceutics, ISSN 1543-8384, 12/2015, Volume 12, Issue 12, pp. 4226 - 4236
Nucleoside reverse transcriptase inhibitors (NRTIs) are an integral part of the current antiretroviral therapy (ART), which dramatically reduced the mortality... 
HIV-1 | macrophages | nucleoside reverse transcriptase inhibitors | prodrugs of zidovudine | humanized mouse (hu-PBL) HIV model | abacavir | nanogel conjugates | mitochondrial toxicity | epsilon-polylysine | lamivudine | MEDICINE, RESEARCH & EXPERIMENTAL | BIODISTRIBUTION | TOXICITY | DELIVERY | ACTIVATED NUCLEOSIDE ANALOGS | NANOPARTICLES | IN-VITRO | ZIDOVUDINE | PHARMACOLOGY & PHARMACY | TYPE-1 | BRAIN | Anti-HIV Agents - pharmacology | Dideoxynucleosides - pharmacology | Polylysine - pharmacology | HIV-1 - drug effects | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Reverse Transcriptase Inhibitors - pharmacology | Zidovudine - pharmacology | Polyethyleneimine - pharmacology | Hep G2 Cells | Drug Therapy, Combination - methods | Animals | HIV Infections - drug therapy | Lamivudine - pharmacology | Mice | Polyethylene Glycols - pharmacology | Index Medicus | humanized mouse (hu-PBL)HIV model | prodrugs of Zidovudine | Abacavir | Lamivudine
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Poly(I:C) as cancer vaccine adjuvant: Knocking on the door of medical breakthroughs
by Ammi, Rachid and De Waele, Jorrit and Willemen, Yannick and Van Brussel, Ilse and Schrijvers, Dorien M and Lion, Eva and Smits, Evelien L.J
Pharmacology and Therapeutics, ISSN 0163-7258, 02/2015, Volume 146, pp. 120 - 131
Although cancer vaccination has yielded promising results in patients, the objective response rates are low. The right choice of adjuvant might improve the... 
Cancer vaccine | Adjuvant | TLR | Poly(I:C) | Poly-ICLC | Anti-tumor immunity | DENDRITIC CELLS | COMBINED IMMUNIZATION | POLYRIBOINOSINIC-POLYRIBOCYTIDYLIC ACID | OVARIAN-CANCER | TOLL-LIKE RECEPTOR-3 | T-CELL RESPONSES | NK CELLS | L-LYSINE | POLYCYTIDYLIC ACID | PHARMACOLOGY & PHARMACY | PHASE-I | Carboxymethylcellulose Sodium - therapeutic use | Polylysine - pharmacology | Carboxymethylcellulose Sodium - analogs & derivatives | Poly I-C - pharmacology | Adjuvants, Immunologic - pharmacology | Polylysine - analogs & derivatives | Cancer Vaccines - pharmacology | Humans | Polylysine - therapeutic use | Cancer Vaccines - therapeutic use | Animals | Carboxymethylcellulose Sodium - pharmacology | Poly I-C - therapeutic use | Adjuvants, Immunologic - therapeutic use | Cancer vaccines
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Resynthesis of phosphatidylinositol 4,5-bisphosphate mediates adaptation of the caffeine response in rat taste receptor cells
by Fang-li Zhao and Scott Herness
The Journal of Physiology, ISSN 0022-3751, 01/2009, Volume 587, Issue 2, pp. 363 - 377
Caffeine, a prototypic bitter stimulus, produces several physiological actions on taste receptor cells that include inhibition of K IR and K V potassium... 
BITTER STIMULI | PHYSIOLOGY | POTASSIUM CURRENTS | INTRACELLULAR CALCIUM | RECTIFYING K+ CHANNELS | PATCH-CLAMP | TRANSDUCTION | MAMMALIAN TASTE | NEUROSCIENCES | VOLTAGE-DEPENDENT CURRENTS | SWEET TASTANTS | PIP2 | Taste Buds - physiology | Tetradecanoylphorbol Acetate - pharmacology | Male | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Phospholipase C beta - antagonists & inhibitors | Delayed Rectifier Potassium Channels - physiology | Protein Kinase C - metabolism | Delayed Rectifier Potassium Channels - drug effects | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Phosphatidylinositol Phosphates - pharmacology | Caffeine - pharmacology | Chromones - pharmacology | Taste Buds - drug effects | Polylysine - pharmacology | Serum Albumin, Bovine - pharmacology | Potassium Channels, Inwardly Rectifying - drug effects | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Rats | Taste Buds - cytology | Sulfonamides - pharmacology | Taste - physiology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Phosphatidylinositol 4,5-Diphosphate - antagonists & inhibitors | Rats, Sprague-Dawley | Patch-Clamp Techniques | Animals | Taste - drug effects | Androstadienes - pharmacology | Potassium Channels, Inwardly Rectifying - physiology | Phosphatidylinositol 4,5-Diphosphate - pharmacology | Phosphatidylinositol 4,5-Diphosphate - biosynthesis | Benzylamines - pharmacology | Physiological aspects | Phosphatidylinositol | Serum albumin | Calcium-binding proteins | Protein kinases | Caffeine | Index Medicus | Neuroscience
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Effect of Cell-Photosensitizer Binding and Cell Density on Microbial Photoinactivation
by Tatiana N. Demidova and Michael R. Hamblin
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2005, Volume 49, Issue 6, pp. 2329 - 2335
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
Photosensitizing Agents - chemistry | Escherichia coli - drug effects | Porphyrins - chemistry | Photosensitizing Agents - metabolism | Polylysine - chemistry | Candida albicans - metabolism | Porphyrins - metabolism | Candida albicans - growth & development | Rose Bengal - pharmacology | Rose Bengal - metabolism | Microbial Sensitivity Tests | Polylysine - metabolism | Tolonium Chloride - metabolism | Photosensitizing Agents - pharmacology | Rose Bengal - chemistry | Candida albicans - drug effects | Light | Escherichia coli - metabolism | Radiation-Sensitizing Agents - chemistry | Escherichia coli - growth & development | Staphylococcus aureus - metabolism | Polylysine - pharmacology | Radiation-Sensitizing Agents - pharmacology | Porphyrins - pharmacology | Tolonium Chloride - chemistry | Radiation-Sensitizing Agents - metabolism | Tolonium Chloride - pharmacology | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Mechanisms of Action | Physiological Effects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text The Natural Antimicrobial Peptide Subtilosin Acts Synergistically with Glycerol Monolaurate, Lauric Arginate, and Δ-Poly-l-Lysine against Bacterial Vaginosis-Associated Pathogens but Not Human Lactobacilli
by Katia Sutyak Noll and Mark N. Prichard and Arkady Khaykin and Patrick J. Sinko and Michael L. Chikindas
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2012, Volume 56, Issue 4, pp. 1756 - 1761
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
LISTERIA-MONOCYTOGENES | GARDNERELLA-VAGINALIS | IN-VITRO | DESIGN | BACILLUS-SUBTILIS | VIRUS TYPE-1 EXPRESSION | ANAEROBIC-BACTERIA | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | INFECTION | DRUG-COMBINATION | PREGNANCY | Polylysine - pharmacology | Humans | Bacteria - drug effects | Peptides, Cyclic - pharmacology | Monoglycerides - pharmacology | Arginine - analogs & derivatives | Drug Synergism | Microbial Sensitivity Tests | Lactobacillus - drug effects | Vaginosis, Bacterial - microbiology | Arginine - pharmacology | Bacteriocins - pharmacology | Female | Laurates - pharmacology | Anti-Bacterial Agents - pharmacology | Gardnerella vaginalis - drug effects | Kinetics | Susceptibility
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Antimicrobial activity and cell selectivity of synthetic and biosynthetic cationic polymers
by Venkatesh, Mayandi and Barathi, Veluchamy Amutha and Goh, Eunice Tze Leng and Anggara, Raditya and Fazil, Mobashar Hussain Urf Turabe and Ng, Alice Jie Ying and Harini, Sriram and Aung, Thet Tun and Fox, Stephen John and Liu, Shouping and Yang, Liang and Barkham, Timothy Mark Sebastian and Loh, Xian Jun and Verma, Navin Kumar and Beuerman, Roger W and Lakshminarayanan, Rajamani
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 2017, Volume 61, Issue 10
The mammalian and microbial cell selectivity of synthetic and biosynthetic cationic polymers has been investigated. Among the polymers with peptide backbones,... 
Antimicrobial activity | Membrane selectivity | Cell selectivity | Rapid bactericidal activity | Cationic polymers | Superior biocompatibility index | Topical bacterial infections | superior biocompatibility index | EFFICACY | cationic polymers | rapid bactericidal activity | BIOFILMS | MICROBIOLOGY | antimicrobial activity | cell selectivity | membrane selectivity | ANTISEPTICS | STRATEGIES | STAPHYLOCOCCUS | PEPTIDES | WOUNDS | RESISTANCE | CHLORHEXIDINE | PHARMACOLOGY & PHARMACY | topical bacterial infections | POVIDONE-IODINE | Cell Line | Polylysine - pharmacology | Rabbits | Staphylococcal Infections - drug therapy | Keratitis - microbiology | Pseudomonas Infections - drug therapy | Humans | Antimicrobial Cationic Peptides - pharmacology | Polyethyleneimine - pharmacology | Aziridines - pharmacology | Pseudomonas aeruginosa - drug effects | Microbial Sensitivity Tests | Animals | Candida albicans - drug effects | Candidiasis - drug therapy | Fibroblasts - drug effects | Allylamine - pharmacology | Polymers - chemistry | Anti-Bacterial Agents - pharmacology | Staphylococcus aureus - drug effects | Keratitis - drug therapy | Cell Membrane - drug effects | Disease Models, Animal
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Polymersomes from Polypeptide Containing Triblock Co‐ and Terpolymers for Drug Delivery against Pancreatic Cancer: Asymmetry of the External Hydrophilic Blocks
by Iatrou, Hermis and Dimas, Konstantinos and Gkikas, Manos and Tsimblouli, Chrisida and Sofianopoulou, Sosanna
Macromolecular Bioscience, ISSN 1616-5187, 09/2014, Volume 14, Issue 9, pp. 1222 - 1238
Well‐defined amphiphilic polymers of the ABA and ABC type are synthesized, where A is poly(L‐lysine hydrochloride) (PLL), B is poly(γ‐benzyl‐(d7) L‐glutamate)... 
nanotechnology | pancreatic cancer | nanoparticles | polymersomes | polypeptides | Nanoparticles | Polypeptides | Pancreatic cancer | Polymersomes | Nanotechnology | MATERIALS SCIENCE, BIOMATERIALS | POLYMER SCIENCE | VESICLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOXORUBICIN | MICELLES | NANO | POLYETHYLENIMINATED FUNCTIONAL POLYMERS | IN-VIVO | SYSTEMS | DEGRADABLE CHIMERIC POLYMERSOMES | POLYOXYPROPYLENEDIAMINES | Paclitaxel - pharmacology | Pancreatic Neoplasms - metabolism | Antibiotics, Antineoplastic - pharmacology | Nanoparticles - chemistry | Humans | Polyethylene Glycols - chemistry | Polylysine - chemistry | Doxorubicin - chemistry | Drug Carriers - chemistry | Pancreatic Neoplasms - drug therapy | Polyglutamic Acid - analogs & derivatives | Paclitaxel - chemistry | Polyglutamic Acid - pharmacology | Antibiotics, Antineoplastic - chemistry | Polyethylene Glycols - pharmacology | Polylysine - pharmacology | Pancreatic Neoplasms - pathology | Antineoplastic Agents, Phytogenic - chemistry | Drug Carriers - chemical synthesis | Polyglutamic Acid - chemical synthesis | Drug Carriers - pharmacology | Polyglutamic Acid - chemistry | Polylysine - chemical synthesis | Cell Line, Tumor | Polyethylene Glycols - chemical synthesis | Antineoplastic Agents, Phytogenic - pharmacology | Doxorubicin - pharmacology | Drug Screening Assays, Antitumor | Invertebrates | Index Medicus | Surgical implants | Vesicles | Asymmetry | Hydrochlorides | Biocompatibility | In vitro testing | Polymers | Doxorubicin | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Synthesis and In Vivo Antitumor Efficacy of PEGylated Poly(l-lysine) Dendrimer−Camptothecin Conjugates
by Fox, Megan E and Guillaudeu, Steve and Fréchet, Jean M. J and Jerger, Katherine and Macaraeg, Nichole and Szoka, Francis C
Molecular Pharmaceutics, ISSN 1543-8384, 10/2009, Volume 6, Issue 5, pp. 1562 - 1572
Polymer conjugates of camptothecin (CPT) have been pursued as a solution to the difficulties present in treating cancers with CPT and its derivatives. Covalent... 
Camptothecin | Dendrimer | Drug delivery | PEG | Poly(L-lysine) | Colon carcinoma | DRUG-DELIVERY | TUNABLE MOLECULAR-WEIGHT | MACROMOLECULAR THERAPEUTICS | colon carcinoma | poly(L-lysine) | camptothecin | TUMOR-BEARING MICE | dendrimer | PHARMACOLOGY & PHARMACY | LYSINE DENDRIMERS | BOW-TIE HYBRIDS | ADVANCED SOLID MALIGNANCIES | POLYETHYLENE-GLYCOL | PHASE-I | BIOLOGICAL APPLICATIONS | Polylysine - analogs & derivatives | Humans | Camptothecin - chemical synthesis | Tissue Distribution | Female | Molecular Structure | Dendrimers - pharmacology | Camptothecin - analogs & derivatives | Polyethylene Glycols - pharmacology | Camptothecin - pharmacokinetics | Polylysine - pharmacology | Antineoplastic Agents, Phytogenic - chemical synthesis | Dendrimers - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Dendrimers - chemical synthesis | Drug Carriers - chemical synthesis | Polylysine - pharmacokinetics | Antineoplastic Agents, Phytogenic - toxicity | HT29 Cells | Animals | Mice, Nude | Polylysine - chemical synthesis | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Polyethylene Glycols - chemical synthesis | Antineoplastic Agents, Phytogenic - pharmacology | Camptothecin - pharmacology | Neoplasms, Experimental - drug therapy | Drug Screening Assays, Antitumor | Index Medicus | drug delivery
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery
by Plank, Christian and Mechtler, Karl and Szoka Jr, Francis C and Wagner, Ernst
Human Gene Therapy, ISSN 1043-0342, 08/1996, Volume 7, Issue 12, pp. 1437 - 1446
We have examined the complement-activating properties of synthetic cationic molecules and their complexes with DNA. Commonly used gene delivery vehicles... 
DEPENDENT PHAGOCYTOSIS | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | POLYMERIC IMMUNOGLOBULIN RECEPTOR | K DB BIOTECHNOLOGY & APPLIED MICROBIOLOGY | K KM GENETICS & HEREDITY | THERAPY | INVIVO | TRANSFERRIN | K QA MEDICINE, RESEARCH & EXPERIMENTAL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | PLASMID DNA | GENETICS & HEREDITY | CATIONIC LIPOSOME COMPLEXES | EXPRESSION | Glycine - analogs & derivatives | Fatty Acids, Monounsaturated - pharmacology | Injections, Intravenous | Genetic Vectors - administration & dosage | DNA, Recombinant - administration & dosage | Humans | Polylysine - chemistry | Quaternary Ammonium Compounds - chemistry | Glycine - chemistry | Cations - pharmacology | DNA, Recombinant - chemical synthesis | Fatty Acids, Monounsaturated - chemistry | Complement Activation - drug effects | Spermine - analogs & derivatives | Gene Transfer Techniques | Polylysine - pharmacology | Cations - chemistry | Genetic Vectors - chemistry | Spermine - chemistry | Phospholipids - chemistry | Phospholipids - pharmacology | Liposomes - chemistry | Animals | Genetic Vectors - pharmacology | Glycine - pharmacology | Phosphatidylethanolamines - pharmacology | Spermine - pharmacology | DNA, Recombinant - pharmacology | Sheep - blood | Phosphatidylethanolamines - chemistry | Quaternary Ammonium Compounds - pharmacology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Effect of functionalization of multilayered polyelectrolyte films on motoneuron growth
by VodouhĂȘ, Constant and Schmittbuhl, Matthieu and Boulmedais, Fouzia and Bagnard, Dominique and Vautier, Dominique and Schaaf, Pierre and Egles, Christophe and Voegel, Jean-Claude and Ogier, Joelle
Biomaterials, ISSN 0142-9612, 2005, Volume 26, Issue 5, pp. 545 - 554
We studied in vitro cell-substrate interaction of motoneurons with functionalized polylectrolyte films. Thin polylectrolyte films were built on glass by... 
Surface modification | Bioactivity | Growth factors | Nerve regeneration | Cell spreading | THIN-FILMS | MATERIALS SCIENCE, BIOMATERIALS | growth factors | ENGINEERING, BIOMEDICAL | surface modification | DEPOSITION | cell spreading | GUIDANCE | ADSORPTION | LAYERS | SEMAPHORINS | MOLECULES | IN-VITRO | bioactivity | CHONDROSARCOMA CELLS | nerve regeneration | SURFACES | Anions - pharmacology | Humans | DNA, Complementary - genetics | Nanostructures | Kidney | Brain-Derived Neurotrophic Factor - pharmacology | Polyglutamic Acid - pharmacology | Transfection | Neurites - ultrastructure | Motor Neurons - cytology | Microscopy, Atomic Force | Spinal Cord - cytology | Motor Neurons - drug effects | Semaphorin-3A - genetics | Polylysine - pharmacology | Cell Culture Techniques - instrumentation | Cells, Cultured | Semaphorin-3A - pharmacology | Materials Testing | Polyethyleneimine - pharmacology | Cell Adhesion - drug effects | Sulfonic Acids - pharmacology | Semaphorin-3A - administration & dosage | Brain-Derived Neurotrophic Factor - administration & dosage | Tissue Engineering - instrumentation | Polyamines - pharmacology | Animals | Image Processing, Computer-Assisted | Spectrum Analysis - methods | Polymers - pharmacology | Electrolytes - pharmacology | Mice
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights